CN101961482A - Immunity enhancer for aquatic animals - Google Patents

Immunity enhancer for aquatic animals Download PDF

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Publication number
CN101961482A
CN101961482A CN2010102072843A CN201010207284A CN101961482A CN 101961482 A CN101961482 A CN 101961482A CN 2010102072843 A CN2010102072843 A CN 2010102072843A CN 201010207284 A CN201010207284 A CN 201010207284A CN 101961482 A CN101961482 A CN 101961482A
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Prior art keywords
parts
weight
immunity
immunity enhancer
component
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CN2010102072843A
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Chinese (zh)
Inventor
伦艳霞
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Tianjin Shengji Group Co Ltd
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Tianjin Shengji Group Co Ltd
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Priority to CN2010102072843A priority Critical patent/CN101961482A/en
Publication of CN101961482A publication Critical patent/CN101961482A/en
Pending legal-status Critical Current

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  • Fodder In General (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to an immunity enhancer for aquatic animals, which is characterized in that each 100 parts of immunity enhancer is prepared by uniformly mixing the following components: 1-10 parts of vitamin C, 1-5 parts of small peptide, 10-50 parts of astragalus polysaccharide of which the weight concentration is greater than 70% and balance of pharmaceutically applicable auxiliary material as a carrier. The preparation method of the immunity enhancer comprises the following steps: weighing each component of the composition in parts by weight, mixing, stirring uniformly, and sieving with a sieve of 80 meshes to obtain a finished product. The auxiliary material is one of anhydrous sugar, oral sugar and corn starch. The immunity enhancer of the invention has the advantages of organic combination of the components, reasonable formula, complementary action, simple preparation and obvious effect, can farthest exert the function of each component, not only can be applied externally but also can be taken orally, has anti-stress effect, improves the feeding efficiency, promotes the growth, simultaneously greatly improves the organic immunity of the aquatic animals, enhances the disease resisting capability, and improves the survival rate.

Description

The aquatic animal immunostimulant
Technical field
The present invention relates to a kind of immunostimulant, particularly relate to a kind of aquatic animal immunostimulant.
Background technology
Along with the raising of intensive culture degree, the deterioration of breeding environment, aquatic animal are being faced with increasing stressors, and, water pollution excessive as stocking density, abrupt change of climate, medicine irritation, long-distance transport, feed nutrition are improper etc.Slightly stress exert an influence to the growth of aquatic animal normal growth, serious its immunity of organisms that causes descends, and induces an illness even death.Therefore, reduce or eliminate the stressors of culturing fish and shrimp, except carrying out the scientific feeding management, also should in bait, add relevant immunostimulant as the case may be; From improving the aquatic products disease resistance.
Therefore, providing a kind of reasonable recipe, easy, the obvious results aquatic animal immunostimulant of preparation, is one of these those skilled in the art problem that should address.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, provide a kind of and can external can take the aquatic animal immunostimulant orally again.
The technical scheme that this utility model adopted is for achieving the above object:
A kind of aquatic animal immunostimulant, it is characterized in that forming by following component uniform mixing for unit of weight: vitamin C 1-10 part by each hundred parts, little peptide 1-5 part, astragalus polysaccharides 10-50 part, press the HPLC(high performance liquid chromatography) measure, described astragalus polysaccharides weight concentration is greater than 70%, and surplus is a carrier for the adjuvant that pharmaceutically is suitable for; Take by weighing each component of above-mentioned composition by weight, mix, stir, cross 80 mesh sieves.
By per hundred parts is that unit of weight is made up of following component uniform mixing: 9 parts of vitamin Cs; 1 part of little peptide, 20 parts of astragalus polysaccharidess, described astragalus polysaccharides weight concentration is greater than 70%, and surplus is a carrier for the adjuvant that pharmaceutically is suitable for; Take by weighing each component of above-mentioned composition by weight, mix, stir, cross 80 mesh sieves.
Described adjuvant is a kind of in no molasses sugar, oral glucose, the corn starch; Preferred corn starch.
The characteristic of each component and effect in the product of the present invention:
Vitamin C (Vc) claim ascorbic acid again, owing to lack the enzyme of synthetic this vitamin in the aquatic animal bodies such as fish and shrimp, therefore can only take in from bait.In case lack, often cause animal blood capillary fragility to improve, permeability increases, stress the time be prone to the hemorrhage and subcutaneous hemorrhage of epidermis, visceral hemorrhage when serious causes anemia then.Can cause that also intestinal wall toughness reduces, elasticity and low in glossiness, the digestive juice secretion ability drop influences the digestion and the absorption of nutrient substance.It is bad to show skeleton development simultaneously, the sclerotin softness, and skeleton deformity, immunocompetence descends, and wound healing is slow.And the raising of cultivation density, the increasing of daily ration, feeding quantity, the deterioration of water quality, the thickening of bottom material of pond for breeding, the comprehensive function of the factors such as excessive interpolation of the short long agent of chemistry has more aggravated to culture the generation of aquatic animal stress disease.
Little peptide (SP) generally is meant the oligopeptide of being made up of 2~3 aminoacid (Oli restrains opeptide), is that the animal degrade proteins is the intermediate product in the aminoacid process, is the proteinic important form of Animal nutrition.In the aquatic product feedstuff, add little peptide, can promote amino acid whose absorption and proteins deposited, improve aquatic animal absorbing mineral, promotion is ingested, and improves bait efficient, promotes the growth of aquatic animal, improve fertility performance, improve disease defence capability and immunity.Have the little Toplink inhibition of antibacterial activity and kill the intravital pathogenic microorganism of animal, reduce or eliminate the stress of disease, improve the health level of fish, improve survival rate the fish body.
Radix Astragali sweet in the mouth, warm in nature is returned lung, spleen channel.The effect that invigorating QI to consolidate the body surface resistance, promoting pus discharge and tissue regeneration strengthening are arranged.The pharmacological action of the Radix Astragali: the effect of enhancing human body immunity function; Anti-hepatic fibrosis, the liver protecting, transaminase lowering, the effect of digestive system aspects such as anti-alimentary tract ulcer; The ischemic nephropathy there is protective effect; Antitumaous effect, antibiotic and suppress virus function etc.Astragalus polysaccharides is the polysaccharide of glucose and arabinose, is the class material that content at most in the Radix Astragali, immunocompetence is stronger, has enhance immunity and antivirus action.
The starch that is adopted: mainly play binding agent.
Each component is pharmaceutical grade among the present invention.
Preparation of the present invention is applicable to various premix material, pellet, semi-humid feedstuff.When the raiser adds on a small quantity, also can be sprayed on the pellet surface, dry the back and use behind 10 times of the preparation dilute with waters of the present invention.Per 100 grams preparation of the present invention is prepared double centner bait, or splashes culturing the pond entirely after the preparation dissolving of the present invention, and consumption is 300~500 gram/mus rice; Logotype 3-5 days, preventive dose can reduce by half; Or according to practical situation interpolation as one sees fit.
The invention has the beneficial effects as follows: preparation of the present invention is with above-mentioned each component organic assembling, complement each other, can bring into play the function of each component to greatest extent, can external can take orally again, not only has anti-stress effect, improve grazing rate, promote growth, improve the immunity of aquatic animal body simultaneously greatly.
The specific embodiment
Below in conjunction with preferred embodiment, details are as follows to the specific embodiment, feature that foundation this utility model provides:
Every part of embodiment 1(is by 1 kilogram)
Take by weighing 9 kilograms of vitamin Cs by weight, 1 kilogram of little peptide, 20 kilograms of astragalus polysaccharidess, described astragalus polysaccharides weight concentration is greater than 70%, 70 kilograms of corn starchs; Mix, stir, cross 80 mesh sieves, promptly make a kind of aquatic animal immunostimulant.
Described adjuvant is a kind of in no molasses sugar, oral glucose, the corn starch.
Embodiment 2
Take by weighing 8 kilograms of vitamin Cs by weight; 2 kilograms of little peptides, 30 kilograms of astragalus polysaccharidess, 60 kilograms of corn starchs; Mix, stir, cross 80 mesh sieves.
Other is with embodiment 1.
Embodiment 3
Take by weighing 3 kilograms of vitamin Cs by weight; 4 kilograms of little peptides, 48 kilograms of astragalus polysaccharidess, 45 kilograms of corn starchs; Mix, stir, cross 80 mesh sieves.
Other is with embodiment 1.
The clinical practice experiment embodiment:
Yichun City Jiang Fengmao pool reservoir, area 2.13hm 2, mean depth 2.5m puts Ctenopharyngodon idellus winter sheet fingerling 1.6 ten thousand tails in a suitable place to breed.The morbidity of beginning in July 1 Ctenopharyngodon idellus is dead, and about every day dead 10 tails and be and slightly increase trend, dead Ctenopharyngodon idellus 18 tails picked up disease fish (about 1 kilogram/tail) and diagnosed July 8, were Ctenopharyngodon idellus " enteritis type " hemorrhagic disease and liver and gallbladder syndrome.Only carried out full storehouse with the sudden and violent blood of life the same day and splash, and mixed 100 kilogram of feed with preparation 100 grams of the present invention every day simultaneously and throw something and feed 1 time, threw something and fed continuously 6 days, basic controlling is lived dead, the practical function highly significant.
Above-mentioned detailed description of aquatic animal being carried out with immunostimulant with reference to embodiment; be illustrative rather than determinate; can exemplify out several embodiment according to institute's limited range,, should belong within protection scope of the present invention therefore in the variation and the modification that do not break away under the general plotting of the present invention.

Claims (3)

1. aquatic animal immunostimulant, it is characterized in that forming by following component uniform mixing for unit of weight: vitamin C 1-10 part by each hundred parts, little peptide 1-5 part, astragalus polysaccharides 10-50 part, described astragalus polysaccharides weight concentration is greater than 70%, and surplus is a carrier for the adjuvant that pharmaceutically is suitable for; Take by weighing each component of above-mentioned composition by weight, mix, stir, cross 80 mesh sieves.
2. aquatic animal immunostimulant according to claim 1 is characterized in that being made up of following component uniform mixing for unit of weight by per hundred parts: 9 parts of vitamin Cs; 1 part of little peptide, 20 parts of astragalus polysaccharidess, described astragalus polysaccharides weight concentration is greater than 70%, and surplus is a carrier for the adjuvant that pharmaceutically is suitable for; Take by weighing each component of above-mentioned composition by weight, mix, stir, cross 80 mesh sieves.
3. aquatic animal immunostimulant according to claim 1 and 2 is characterized in that described adjuvant is a kind of in no molasses sugar, oral glucose, the corn starch.
CN2010102072843A 2010-06-23 2010-06-23 Immunity enhancer for aquatic animals Pending CN101961482A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010102072843A CN101961482A (en) 2010-06-23 2010-06-23 Immunity enhancer for aquatic animals

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Application Number Priority Date Filing Date Title
CN2010102072843A CN101961482A (en) 2010-06-23 2010-06-23 Immunity enhancer for aquatic animals

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CN101961482A true CN101961482A (en) 2011-02-02

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511697A (en) * 2012-01-13 2012-06-27 河南工业大学 Special composite immune-enhancer for Yellow River carp
CN106173565A (en) * 2016-09-14 2016-12-07 中国水产科学研究院淡水渔业研究中心 A kind of compounding powder strengthening aquatic animal nonspecific immunity and preparation method thereof
CN106511626A (en) * 2016-12-07 2017-03-22 重庆文洪水产品养殖有限公司 Antioxidant antibiotic-free immunoenhancer for aquatic animals and preparation method of antioxidant antibiotic-free immunoenhancer
CN110463632A (en) * 2018-05-11 2019-11-19 南京农业大学 A kind of natural additive improving leech anti-heat stress ability
CN114788554A (en) * 2022-04-06 2022-07-26 诺立(上海)生物工程有限公司 Nutritional composition for regulating immunity of aquatic animals and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
李清等: "小肽对鲤鱼免疫力的影响", 《饲料研究》 *
温周瑞等: "中草药对水产动物免疫作用研究进展", 《水利渔业》 *
许明等: "黄芪多糖防治草鱼出血病的研究", 《安徽农业科学》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511697A (en) * 2012-01-13 2012-06-27 河南工业大学 Special composite immune-enhancer for Yellow River carp
CN106173565A (en) * 2016-09-14 2016-12-07 中国水产科学研究院淡水渔业研究中心 A kind of compounding powder strengthening aquatic animal nonspecific immunity and preparation method thereof
CN106511626A (en) * 2016-12-07 2017-03-22 重庆文洪水产品养殖有限公司 Antioxidant antibiotic-free immunoenhancer for aquatic animals and preparation method of antioxidant antibiotic-free immunoenhancer
CN110463632A (en) * 2018-05-11 2019-11-19 南京农业大学 A kind of natural additive improving leech anti-heat stress ability
CN114788554A (en) * 2022-04-06 2022-07-26 诺立(上海)生物工程有限公司 Nutritional composition for regulating immunity of aquatic animals and preparation method thereof

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Application publication date: 20110202