CN114788554A - Nutritional composition for regulating immunity of aquatic animals and preparation method thereof - Google Patents

Nutritional composition for regulating immunity of aquatic animals and preparation method thereof Download PDF

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Publication number
CN114788554A
CN114788554A CN202210355986.9A CN202210355986A CN114788554A CN 114788554 A CN114788554 A CN 114788554A CN 202210355986 A CN202210355986 A CN 202210355986A CN 114788554 A CN114788554 A CN 114788554A
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China
Prior art keywords
parts
polysaccharide powder
aquatic animals
nutritional composition
immunity
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Pending
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CN202210355986.9A
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Chinese (zh)
Inventor
张超
易明启
李继仁
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Nori Shanghai Bioengineering Co ltd
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Nori Shanghai Bioengineering Co ltd
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Priority to CN202210355986.9A priority Critical patent/CN114788554A/en
Publication of CN114788554A publication Critical patent/CN114788554A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/153Nucleic acids; Hydrolysis products or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2292Thymosin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Physiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a nutritional composition for regulating immunity of aquatic animals and a preparation method thereof, and relates to a nutritional composition for the aquatic animals. Comprises 20-30 parts of cordyceps polysaccharide powder, 10-15 parts of ganoderan powder, 8-12 parts of fermented astragalus polysaccharide powder, 10-12 parts of lentinan, 5-10 parts of thymosin and 3-6 parts of adenosine triphosphate. The invention can treat immune diseases of aquatic animals, has obvious curative effect, improves the immunity of the aquatic animals and increases the resistance.

Description

Nutritional composition for regulating immunity of aquatic animals and preparation method thereof
Technical Field
The invention relates to a nutritional composition for aquatic animals, in particular to a nutritional composition for regulating immunity of the aquatic animals and a preparation method thereof.
Background
A plurality of aquatic animals are delicious and are favorite foods, such as penaeus vannamei, crayfish, weever in California and the like, but the aquatic animals are easily damaged by viruses, and in order to improve the immunity of the aquatic animals, the invention designs the nutritional composition for regulating the immunity of the aquatic animals and the preparation method thereof.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the nutritional composition for regulating the immunity of the aquatic animals and the preparation method thereof, so that the nutritional composition can be used for treating immune diseases of the aquatic animals, has an obvious curative effect, improves the immunity of the aquatic animals and increases the resistance.
In order to achieve the purpose, the invention is realized by the following technical scheme: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20-30 parts, Ganoderma polysaccharide powder 10-15 parts, fermented Astragalus polysaccharide powder 8-12 parts, lentinan 10-12 parts, thymosin 5-10 parts, and adenosine triphosphate 3-6 parts.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 20 parts of cordyceps sinensis polysaccharide powder, 10 parts of ganoderma lucidum polysaccharide powder, 8 parts of fermented astragalus polysaccharide powder, 10 parts of lentinan, 5 parts of thymosin and 3 parts of adenosine triphosphate.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 30 parts of cordyceps sinensis polysaccharide powder, 15 parts of ganoderma lucidum polysaccharide powder, 12 parts of fermented astragalus polysaccharide powder, 12 parts of lentinan, 10 parts of thymosin and 6 parts of adenosine triphosphate.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 25 parts of cordyceps sinensis polysaccharide powder, 12 parts of ganoderma lucidum polysaccharide powder, 10 parts of fermented astragalus polysaccharide powder, 11 parts of lentinan, 8 parts of thymosin and 5 parts of adenosine triphosphate.
A method for preparing a nutritional composition for regulating immunity of aquatic animals comprises the following steps: mixing Cordyceps polysaccharide powder, Ganoderma polysaccharide powder, fermented Astragalus polysaccharide powder, lentinan, thymosin and adenosine triphosphate, and stirring at room temperature.
The invention has the beneficial effects that: the preparation method is simple, and the prepared nutritional composition has the effects of resisting viruses, eliminating evil, strengthening body resistance and regulating immunity, has obvious curative effect on immune diseases of aquatic animals, and can improve immunity and enhance resistance.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
The technical scheme adopted by the specific implementation mode is as follows: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20-30 parts, Ganoderma polysaccharide powder 10-15 parts, fermented Astragalus polysaccharide powder 8-12 parts, lentinan 10-12 parts, thymosin 5-10 parts, and adenosine triphosphate 3-6 parts. The preparation method comprises the following steps: mixing Cordyceps polysaccharide powder, Ganoderma polysaccharide powder, fermented Astragalus polysaccharide powder, lentinan, thymosin and adenosine triphosphate, and stirring at room temperature.
The cordyceps sinensis polysaccharide powder in the specific embodiment is a high-molecular polysaccharide, and is an internationally recognized immunomodulator. Cordyceps polysaccharide has anticancer activity, and can inhibit tumor and enhance resistance of organism to various bacteria, viruses, fungi and parasites.
The secondary metabolite of mycelia of fungus belonging to Ganoderma of Polyporaceae can improve immunity, accelerate blood microcirculation, improve oxygen supply capacity, reduce ineffective oxygen consumption of body in static state, eliminate in vivo free radicals, and improve cell membrane sealing degree.
The fermented Astragalus polysaccharides comprise hexuronic acid, glucose, fructose, rhamnose, arabinose, galacturonic acid and glucuronic acid, and can be used as immunopotentiator or regulator.
Lentinan is an effective active component extracted from high-quality lentinus edodes sporocarp, is a main effective component of lentinus edodes, is a host immunity enhancer (HDP), and has the functions of resisting virus and tumor, regulating immune function, stimulating the formation of interferon and the like according to clinical and pharmacological researches.
Thymosin has the function of regulating and enhancing the cellular immune function of human body.
Adenosine triphosphate is formed by connecting adenine, ribose and 3 phosphate groups, releases more energy during hydrolysis, and is the most direct energy source in organisms.
The composition of the specific embodiment has obvious curative effects on immune diseases of aquatic animals such as white spot virus of south America white shrimp, quince pestivirus of crayfish, herpes virus of weever in California, reovirus, rainbow virus, nocardia virus and the like, and can improve immunity and enhance resistance.
Example 1: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20 g, Ganoderma polysaccharide powder 10 g, fermented Astragalus polysaccharide powder 8 g, lentinan 10 g, thymosin 5 g, and adenosine triphosphate 3 g.
Example 2: the nutritional composition for regulating the immunity of aquatic animals comprises 30 g of cordyceps sinensis polysaccharide powder, 15 g of ganoderma lucidum polysaccharide powder, 12 g of fermented astragalus polysaccharide powder, 12 g of lentinan, 10 g of thymosin and 6 g of adenosine triphosphate.
Example 3: the nutritional composition for regulating the immunity of the aquatic animals comprises 25 g of cordyceps sinensis polysaccharide powder, 12 g of ganoderan powder, 10 g of fermented astragalus polysaccharide powder, 11 g of lentinan, 8 g of thymosin and 5 g of adenosine triphosphate.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, and such changes and modifications are within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (4)

1. A nutritional composition for regulating immunity of aquatic animals is characterized by comprising 20-30 parts of cordyceps sinensis polysaccharide powder, 10-15 parts of ganoderma lucidum polysaccharide powder, 8-12 parts of fermented astragalus polysaccharide powder, 10-12 parts of lentinan, 5-10 parts of thymosin and 3-6 parts of adenosine triphosphate.
2. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 20 parts of cordyceps sinensis polysaccharide powder, 10 parts of ganoderma lucidum polysaccharide powder, 8 parts of fermented astragalus polysaccharide powder, 10 parts of lentinan, 5 parts of thymosin and 3 parts of adenosine triphosphate.
3. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 30 parts of cordyceps sinensis polysaccharide powder, 15 parts of ganoderma lucidum polysaccharide powder, 12 parts of fermented astragalus polysaccharide powder, 12 parts of lentinan, 10 parts of thymosin and 6 parts of adenosine triphosphate.
4. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 25 parts of cordyceps sinensis polysaccharide powder, 12 parts of ganoderma lucidum polysaccharide powder, 10 parts of fermented astragalus polysaccharide powder, 11 parts of lentinan, 8 parts of thymosin and 5 parts of adenosine triphosphate.
CN202210355986.9A 2022-04-06 2022-04-06 Nutritional composition for regulating immunity of aquatic animals and preparation method thereof Pending CN114788554A (en)

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CN202210355986.9A CN114788554A (en) 2022-04-06 2022-04-06 Nutritional composition for regulating immunity of aquatic animals and preparation method thereof

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101683357A (en) * 2008-09-25 2010-03-31 天津生机集团股份有限公司 Astragalus polyose solution for aquatic animals and preparation method thereof
CN101703518A (en) * 2009-09-21 2010-05-12 青岛汉河动植物药业有限公司 Pharmaceutical composition of dsRNA and astragalus polysaccharide and application thereof
CN101961482A (en) * 2010-06-23 2011-02-02 天津生机集团股份有限公司 Immunity enhancer for aquatic animals
US20150265664A1 (en) * 2012-09-13 2015-09-24 Jiangzhong Pharmaceutical Co., Ltd. Traditional chinese medicine combination for regulating immune function and preparation method therefor
CN108835384A (en) * 2018-08-01 2018-11-20 中国海洋大学 A kind of prawn Chinese herbal medicine complex polysaccharide feedstuff additive for immunity enhancement

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101683357A (en) * 2008-09-25 2010-03-31 天津生机集团股份有限公司 Astragalus polyose solution for aquatic animals and preparation method thereof
CN101703518A (en) * 2009-09-21 2010-05-12 青岛汉河动植物药业有限公司 Pharmaceutical composition of dsRNA and astragalus polysaccharide and application thereof
CN101961482A (en) * 2010-06-23 2011-02-02 天津生机集团股份有限公司 Immunity enhancer for aquatic animals
US20150265664A1 (en) * 2012-09-13 2015-09-24 Jiangzhong Pharmaceutical Co., Ltd. Traditional chinese medicine combination for regulating immune function and preparation method therefor
CN108835384A (en) * 2018-08-01 2018-11-20 中国海洋大学 A kind of prawn Chinese herbal medicine complex polysaccharide feedstuff additive for immunity enhancement

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
顾德平等: "《水产动物用药技术问答》", vol. 1, 金盾出版社, pages: 174 - 175 *

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Application publication date: 20220726