CN114788554A - Nutritional composition for regulating immunity of aquatic animals and preparation method thereof - Google Patents
Nutritional composition for regulating immunity of aquatic animals and preparation method thereof Download PDFInfo
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- CN114788554A CN114788554A CN202210355986.9A CN202210355986A CN114788554A CN 114788554 A CN114788554 A CN 114788554A CN 202210355986 A CN202210355986 A CN 202210355986A CN 114788554 A CN114788554 A CN 114788554A
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- 230000036039 immunity Effects 0.000 title claims abstract description 26
- 239000000203 mixture Substances 0.000 title claims abstract description 24
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 23
- 230000001105 regulatory effect Effects 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 150000004676 glycans Chemical class 0.000 claims abstract description 47
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 47
- 239000005017 polysaccharide Substances 0.000 claims abstract description 47
- 239000000843 powder Substances 0.000 claims abstract description 46
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 claims abstract description 16
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- IAJILQKETJEXLJ-KLVWXMOXSA-N (2s,3r,4r,5r)-2,3,4,5-tetrahydroxy-6-oxohexanoic acid Chemical compound O=C[C@H](O)[C@H](O)[C@@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-KLVWXMOXSA-N 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
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- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
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- 239000005715 Fructose Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
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- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- 241000519995 Stachys sylvatica Species 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
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- 239000003623 enhancer Substances 0.000 description 1
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- 235000013305 food Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 230000007236 host immunity Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000002955 immunomodulating agent Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
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- 230000000091 immunopotentiator Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
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- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
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- 230000003068 static effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/153—Nucleic acids; Hydrolysis products or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
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- Animal Husbandry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Birds (AREA)
- Physiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Insects & Arthropods (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a nutritional composition for regulating immunity of aquatic animals and a preparation method thereof, and relates to a nutritional composition for the aquatic animals. Comprises 20-30 parts of cordyceps polysaccharide powder, 10-15 parts of ganoderan powder, 8-12 parts of fermented astragalus polysaccharide powder, 10-12 parts of lentinan, 5-10 parts of thymosin and 3-6 parts of adenosine triphosphate. The invention can treat immune diseases of aquatic animals, has obvious curative effect, improves the immunity of the aquatic animals and increases the resistance.
Description
Technical Field
The invention relates to a nutritional composition for aquatic animals, in particular to a nutritional composition for regulating immunity of the aquatic animals and a preparation method thereof.
Background
A plurality of aquatic animals are delicious and are favorite foods, such as penaeus vannamei, crayfish, weever in California and the like, but the aquatic animals are easily damaged by viruses, and in order to improve the immunity of the aquatic animals, the invention designs the nutritional composition for regulating the immunity of the aquatic animals and the preparation method thereof.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the nutritional composition for regulating the immunity of the aquatic animals and the preparation method thereof, so that the nutritional composition can be used for treating immune diseases of the aquatic animals, has an obvious curative effect, improves the immunity of the aquatic animals and increases the resistance.
In order to achieve the purpose, the invention is realized by the following technical scheme: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20-30 parts, Ganoderma polysaccharide powder 10-15 parts, fermented Astragalus polysaccharide powder 8-12 parts, lentinan 10-12 parts, thymosin 5-10 parts, and adenosine triphosphate 3-6 parts.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 20 parts of cordyceps sinensis polysaccharide powder, 10 parts of ganoderma lucidum polysaccharide powder, 8 parts of fermented astragalus polysaccharide powder, 10 parts of lentinan, 5 parts of thymosin and 3 parts of adenosine triphosphate.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 30 parts of cordyceps sinensis polysaccharide powder, 15 parts of ganoderma lucidum polysaccharide powder, 12 parts of fermented astragalus polysaccharide powder, 12 parts of lentinan, 10 parts of thymosin and 6 parts of adenosine triphosphate.
Preferably, the nutritional composition for regulating the immunity of aquatic animals comprises 25 parts of cordyceps sinensis polysaccharide powder, 12 parts of ganoderma lucidum polysaccharide powder, 10 parts of fermented astragalus polysaccharide powder, 11 parts of lentinan, 8 parts of thymosin and 5 parts of adenosine triphosphate.
A method for preparing a nutritional composition for regulating immunity of aquatic animals comprises the following steps: mixing Cordyceps polysaccharide powder, Ganoderma polysaccharide powder, fermented Astragalus polysaccharide powder, lentinan, thymosin and adenosine triphosphate, and stirring at room temperature.
The invention has the beneficial effects that: the preparation method is simple, and the prepared nutritional composition has the effects of resisting viruses, eliminating evil, strengthening body resistance and regulating immunity, has obvious curative effect on immune diseases of aquatic animals, and can improve immunity and enhance resistance.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
The technical scheme adopted by the specific implementation mode is as follows: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20-30 parts, Ganoderma polysaccharide powder 10-15 parts, fermented Astragalus polysaccharide powder 8-12 parts, lentinan 10-12 parts, thymosin 5-10 parts, and adenosine triphosphate 3-6 parts. The preparation method comprises the following steps: mixing Cordyceps polysaccharide powder, Ganoderma polysaccharide powder, fermented Astragalus polysaccharide powder, lentinan, thymosin and adenosine triphosphate, and stirring at room temperature.
The cordyceps sinensis polysaccharide powder in the specific embodiment is a high-molecular polysaccharide, and is an internationally recognized immunomodulator. Cordyceps polysaccharide has anticancer activity, and can inhibit tumor and enhance resistance of organism to various bacteria, viruses, fungi and parasites.
The secondary metabolite of mycelia of fungus belonging to Ganoderma of Polyporaceae can improve immunity, accelerate blood microcirculation, improve oxygen supply capacity, reduce ineffective oxygen consumption of body in static state, eliminate in vivo free radicals, and improve cell membrane sealing degree.
The fermented Astragalus polysaccharides comprise hexuronic acid, glucose, fructose, rhamnose, arabinose, galacturonic acid and glucuronic acid, and can be used as immunopotentiator or regulator.
Lentinan is an effective active component extracted from high-quality lentinus edodes sporocarp, is a main effective component of lentinus edodes, is a host immunity enhancer (HDP), and has the functions of resisting virus and tumor, regulating immune function, stimulating the formation of interferon and the like according to clinical and pharmacological researches.
Thymosin has the function of regulating and enhancing the cellular immune function of human body.
Adenosine triphosphate is formed by connecting adenine, ribose and 3 phosphate groups, releases more energy during hydrolysis, and is the most direct energy source in organisms.
The composition of the specific embodiment has obvious curative effects on immune diseases of aquatic animals such as white spot virus of south America white shrimp, quince pestivirus of crayfish, herpes virus of weever in California, reovirus, rainbow virus, nocardia virus and the like, and can improve immunity and enhance resistance.
Example 1: a nutritional composition for regulating immunity of aquatic animals comprises Cordyceps polysaccharide powder 20 g, Ganoderma polysaccharide powder 10 g, fermented Astragalus polysaccharide powder 8 g, lentinan 10 g, thymosin 5 g, and adenosine triphosphate 3 g.
Example 2: the nutritional composition for regulating the immunity of aquatic animals comprises 30 g of cordyceps sinensis polysaccharide powder, 15 g of ganoderma lucidum polysaccharide powder, 12 g of fermented astragalus polysaccharide powder, 12 g of lentinan, 10 g of thymosin and 6 g of adenosine triphosphate.
Example 3: the nutritional composition for regulating the immunity of the aquatic animals comprises 25 g of cordyceps sinensis polysaccharide powder, 12 g of ganoderan powder, 10 g of fermented astragalus polysaccharide powder, 11 g of lentinan, 8 g of thymosin and 5 g of adenosine triphosphate.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, and such changes and modifications are within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (4)
1. A nutritional composition for regulating immunity of aquatic animals is characterized by comprising 20-30 parts of cordyceps sinensis polysaccharide powder, 10-15 parts of ganoderma lucidum polysaccharide powder, 8-12 parts of fermented astragalus polysaccharide powder, 10-12 parts of lentinan, 5-10 parts of thymosin and 3-6 parts of adenosine triphosphate.
2. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 20 parts of cordyceps sinensis polysaccharide powder, 10 parts of ganoderma lucidum polysaccharide powder, 8 parts of fermented astragalus polysaccharide powder, 10 parts of lentinan, 5 parts of thymosin and 3 parts of adenosine triphosphate.
3. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 30 parts of cordyceps sinensis polysaccharide powder, 15 parts of ganoderma lucidum polysaccharide powder, 12 parts of fermented astragalus polysaccharide powder, 12 parts of lentinan, 10 parts of thymosin and 6 parts of adenosine triphosphate.
4. The nutritional composition for regulating immunity of aquatic animals according to claim 1, comprising 25 parts of cordyceps sinensis polysaccharide powder, 12 parts of ganoderma lucidum polysaccharide powder, 10 parts of fermented astragalus polysaccharide powder, 11 parts of lentinan, 8 parts of thymosin and 5 parts of adenosine triphosphate.
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CN202210355986.9A CN114788554A (en) | 2022-04-06 | 2022-04-06 | Nutritional composition for regulating immunity of aquatic animals and preparation method thereof |
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CN202210355986.9A CN114788554A (en) | 2022-04-06 | 2022-04-06 | Nutritional composition for regulating immunity of aquatic animals and preparation method thereof |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101683357A (en) * | 2008-09-25 | 2010-03-31 | 天津生机集团股份有限公司 | Astragalus polyose solution for aquatic animals and preparation method thereof |
CN101703518A (en) * | 2009-09-21 | 2010-05-12 | 青岛汉河动植物药业有限公司 | Pharmaceutical composition of dsRNA and astragalus polysaccharide and application thereof |
CN101961482A (en) * | 2010-06-23 | 2011-02-02 | 天津生机集团股份有限公司 | Immunity enhancer for aquatic animals |
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