CN101972469A - Immune preparation for aquatic animals - Google Patents
Immune preparation for aquatic animals Download PDFInfo
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- CN101972469A CN101972469A CN2010102569790A CN201010256979A CN101972469A CN 101972469 A CN101972469 A CN 101972469A CN 2010102569790 A CN2010102569790 A CN 2010102569790A CN 201010256979 A CN201010256979 A CN 201010256979A CN 101972469 A CN101972469 A CN 101972469A
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Abstract
The invention relates to an immune preparation for aquatic animals. The immune preparation comprises the following component in percentage by weight: 1-30% of vitamin C, 1-5% of small peptide, 10-20% of mannan oligosaccharides, 20-40% of yeast beta-glucan and the balance of a pharmaceutically acceptable auxiliary material serving as a carrier. The immune preparation is prepared by the following steps: weighing the components according to weight percentage, mixing the components, evenly stirring, and enabling the mixture to pass through a sieve with the granularity of 80 meshes, wherein the auxiliary material is one of anhydrous sugar, oral glucose and corn starch. The components of the preparation of the invention are organically combined and supplement each other, and the functions of the components can be expressed up to the hilt; and the immune preparation can be used externally or be taken orally, not only has anti-stress effect, but also can improve the ingestion rate of the aquatic animals, promote the growth of the aquatic animals, and greatly improve the immunity of aquatic animal organisms. The immune preparation has the advantages of reasonable formula, simple preparation, convenient use, obvious effect, no drug residue, harmlessness and environmental friendliness.
Description
Technical field
The present invention relates to a kind of aquatic animal medicine, particularly a kind of aquatic animal immune formulation.
Background technology
In recent years, along with raising scattered of aquatic animal moved towards intensive culture gradually.People have also reduced the immunity of aquatic animal body in the output that covets, cause various pathogenic microorganisms to be wreaked havoc.Some new diseases take place in succession, and a large amount of antibiotic and some chemicalses of using in breed, cause the microorganism drug resistance to increase, some have the medicine serious threat of " three cause " (teratogenesis, carcinogenic, mutagenesis) effect and aquatic animal and mankind itself's health.Improving the immunity of aquatic animal, is to reduce aquatic animal disease, guarantees the important behave of aquatic health growth and food safety.
Therefore, providing a kind of reasonable recipe, easy, the obvious results aquatic animal immune formulation of preparation, is one of this field scientific research technical staff important difficult problem of being badly in need of solving.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide a kind of reasonable recipe, simple, easy to use, the effect of preparation significantly, drug residue free and the aquatic animal immune formulation that can external can take orally again.
The technical scheme that this utility model adopted is for achieving the above object:
A kind of aquatic animal immune formulation, % is made up of following component uniform mixing by weight: vitamin C 1-30%, little peptide 1-5%, mannooligo saccharide 10-20%, yeast beta-dextran 20-40%, surplus is a carrier with the adjuvant that pharmaceutically is suitable for; Concrete implementation step: % takes by weighing above-mentioned each component by weight, mixes, and stirs, and crosses 80 mesh sieves, promptly makes.
% is made up of following component uniform mixing by weight: vitamin C 10%, and little peptide 2%, mannooligo saccharide 20%, yeast beta-dextran 20%, pharmaceutically the adjuvant of Shi Yonging is a carrier 48%; Concrete implementation step: % takes by weighing above-mentioned each component by weight, mixes, and stirs, and crosses 80 mesh sieves, promptly makes.
Described adjuvant is a kind of in no molasses sugar, oral glucose, the corn starch, preferred corn starch.
The characteristic of each component and effect in the product of the present invention:
Vitamin C (Vc) claim ascorbic acid again, owing to lack the enzyme of synthetic this vitamin in the aquatic animal bodies such as fish and shrimp, therefore can only take in from bait.In case lack, often cause animal blood capillary fragility to improve, permeability increases, stress the time be prone to the hemorrhage and subcutaneous hemorrhage of epidermis, visceral hemorrhage when serious causes anemia then.Can cause that also intestinal wall toughness reduces, elasticity and low in glossiness, the digestive juice secretion ability drop influences the digestion and the absorption of nutrient substance.It is bad to show skeleton development simultaneously, the sclerotin softness, and skeleton deformity, immunocompetence descends, and wound healing is slow.And the raising of cultivation density, the increasing of daily ration, feeding quantity, the deterioration of water quality, the thickening of bottom material of pond for breeding, the comprehensive function of the factors such as excessive interpolation of the short long agent of chemistry has more aggravated to culture the generation of aquatic animal stress disease.
Little peptide (SP) generally is meant the oligopeptide of being made up of 2～3 aminoacid, is that the animal degrade proteins is the intermediate product in the aminoacid process, is the proteinic important form of Animal nutrition.In the aquatic product feedstuff, add little peptide, can promote amino acid whose absorption and proteins deposited, improve aquatic animal absorbing mineral, promotion is ingested, and improves bait efficient, promotes the growth of aquatic animal, improve fertility performance, improve disease defence capability and immunity.Have the little Toplink inhibition of antibacterial activity and kill the intravital pathogenic microorganism of animal, reduce or eliminate the stress of disease, improve the health level of fish, improve survival rate the fish body.
Mannooligo saccharide (MOS) obtains from the separation of beer yeast cells wall.The basis of cell wall comprises the protein of 30% mannooligo saccharide, 30% glucose and 12.5%.MOS uses one of more oligosaccharide at present on animal, it mainly is to improve the animal body immunologic function by following three aspects: (1) promotes the propagation of animal intestinal back segment probiotics, particularly bacillus bifidus; (2) have immunological adjuvant and antigenic characteristic; (3) activate animal body body fluid and cellular immunization.Add an amount of mannooligo saccharide in the feedstuff, can promote the animal health growth, improve absorbance and the feed conversion rate of animal nutrient substance; Prevent diarrhoea, reduce the quantity of corrupt substances such as ammonia in the feces.Mannooligo saccharide is heat-resisting, stable, pollution-free, noresidue, is a kind of novel green feed additive.
Yeast beta-dextran mainly is present in the internal layer of yeast cell wall, and it plays an important role for the structural strength of keeping body inner cell wall.The polysaccharide that the active structure of beta glucan is made up of glucose unit, their great majority are by β-1,3 combination, and this is a Fructus Vitis viniferae sugar chain ways of connecting.It can activated macrophage, neutrophils etc., therefore can improve the content of leukin, the basic element of cell division and distinct antibodies, stimulates the immune system of body comprehensively.Thereby make body absorb, destroy and remove intravital pathogenic microorganism, and then improved the immunologic function of aquatic animal by phagocytosis.
The starch that is adopted: mainly play binding agent.
Each becomes to belong to pharmaceutical grade among the present invention, is the commercially available prod.
Preparation of the present invention can make an addition to various aquatic animals and grow seedlings and culture premix material, pellet, the semi-humid feedstuff that factory throws something and feeds, not only can take orally but also can external, for example:
(1) mix and raise: the 0.1%-0.3% by forage volume makes an addition in the feedstuff.
(2) sprinkle outside: after this product is diluted with breeding water, evenly splash in full pond, and consumption is 200～250 gram/mus rice, and logotype 3-5 days, preventive dose can reduce by half; Or according to practical situation interpolation as one sees fit.
The invention has the beneficial effects as follows: preparation of the present invention is with above-mentioned each composition organic assembling, complement each other, can bring into play the function of each component to greatest extent, can external oral administration again, not only has anti-stress effect, improve the grazing rate of aquatic animal, promote growth, improve the immunity of aquatic animal body simultaneously greatly.Reasonable recipe of the present invention, simple, easy to use, the effect of preparation significantly, drug residue free, harmless environmental protection.
The specific embodiment
Below in conjunction with preferred embodiment, details are as follows to the specific embodiment, feature that foundation this utility model provides:
Embodiment 1
Take by weighing vitamin C 10kg by weight, little peptide 2kg, mannooligo saccharide 10kg, yeast beta-dextran 20kg, corn starch 58kg; Mix, stir, cross 80 mesh sieves, promptly make a kind of aquatic animal immune formulation.
Described various composition is the commercially available prod.
Embodiment 2
Take by weighing vitamin C 20kg by weight, little peptide 5 kg, mannooligo saccharide 10 kg, yeast beta-dextran 20 kg, corn starch 45 kg; Mix, stir, cross 80 mesh sieves, promptly make.
Other is with embodiment 1.
Embodiment 3
Take by weighing vitamin C 10 kg by weight, little peptide 2 kg, mannooligo saccharide 20 kg, yeast beta-dextran 20 kg, corn starch 48 kg; Mix, stir, cross 80 mesh sieves, promptly make.
Other is with embodiment 1.
Embodiment 4
Take by weighing vitamin C 2kg by weight, little peptide 3 kg, mannooligo saccharide 15 kg, yeast beta-dextran 40 kg, corn starch 40 kg; Mix, stir, cross 80 mesh sieves, promptly make.
Other is with embodiment 1.
The clinical practice experiment embodiment:
Hebei one reservoir is put Ctenopharyngodon idellus kind 1.6 ten thousand tails in a suitable place to breed.The morbidity of last August 1 beginning Ctenopharyngodon idellus is dead, about every day dead 10 tails and be and slightly increase trend, August 8 dead Ctenopharyngodon idellus 18 tails, picking up the disease fish diagnoses, the visible gill filament of the naked eyes band that rots to turn white is yellow, most advanced and sophisticated cartilage exposes, and is stained with mud and mucus, the bacillus that microscopy is as seen elongated in a large number, slide.Went out with malicious aldehyde the same day and carried out dipping, mix 100 kg feedstuff feedings 1 time with preparation 300g of the present invention every day simultaneously, threw something and fed continuously 6 days, basic controlling is lived dead, and there is not other disease to take place when fishing for again, proves that this product strengthens organism immunity of aquatic livestock effect highly significant to October.
Above-mentioned detailed description of aquatic animal being carried out with immune formulation with reference to embodiment; be illustrative rather than determinate; can exemplify out several embodiment according to institute's limited range,, should belong within protection scope of the present invention therefore in the variation and the modification that do not break away under the general plotting of the present invention.
Claims (3)
1. aquatic animal immune formulation is characterized in that % is made up of following component uniform mixing by weight: vitamin C 1-30%, and little peptide 1-5%, mannooligo saccharide 10-20%, yeast beta-dextran 20-40%, surplus is a carrier with the adjuvant that pharmaceutically is suitable for; Concrete implementation step: % takes by weighing above-mentioned each component by weight, mixes, and stirs, and crosses 80 mesh sieves, promptly makes.
2. aquatic animal immune formulation according to claim 1, it is characterized in that % is made up of following component uniform mixing by weight: vitamin C 10%, little peptide 2%, mannooligo saccharide 20%, yeast beta-dextran 20%, pharmaceutically the adjuvant of Shi Yonging is a carrier 48%; Concrete implementation step: % takes by weighing above-mentioned each component by weight, mixes, and stirs, and crosses 80 mesh sieves, promptly makes.
3. aquatic animal immune formulation according to claim 1 and 2 is characterized in that described adjuvant is a kind of in no molasses sugar, oral glucose, the corn starch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102569790A CN101972469A (en) | 2010-08-19 | 2010-08-19 | Immune preparation for aquatic animals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102569790A CN101972469A (en) | 2010-08-19 | 2010-08-19 | Immune preparation for aquatic animals |
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| Publication Number | Publication Date |
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| CN101972469A true CN101972469A (en) | 2011-02-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010102569790A Pending CN101972469A (en) | 2010-08-19 | 2010-08-19 | Immune preparation for aquatic animals |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013053073A1 (en) * | 2011-10-10 | 2013-04-18 | Huang Daiyong | Mannan oligosaccharide-based gastrointestinal tract health factor composition |
| CN105767596A (en) * | 2016-03-17 | 2016-07-20 | 江苏富裕达粮食制品股份有限公司 | Anti-stress enhancer for macrobrachium rosenbergii and application thereof |
| CN107232610A (en) * | 2017-05-25 | 2017-10-10 | 杭州特悘衡康生物科技有限公司 | A kind of carbohydrate composition of beta glucan containing yeast and its application |
| CN110250340A (en) * | 2019-07-18 | 2019-09-20 | 无锡中顺生物技术有限公司 | A kind of complex polysaccharide of aquatic products and its application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053373A (en) * | 2007-05-08 | 2007-10-17 | 朱旺明 | Food attractant growth promoting agent for aquatic animals and its manufacturing technology |
-
2010
- 2010-08-19 CN CN2010102569790A patent/CN101972469A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053373A (en) * | 2007-05-08 | 2007-10-17 | 朱旺明 | Food attractant growth promoting agent for aquatic animals and its manufacturing technology |
Non-Patent Citations (2)
| Title |
|---|
| 伍惠生: "维生素C在水产养殖业的应用", 《河南水产》 * |
| 温周瑞等: "中草药对水产动物免疫作用研究进展", 《水利渔业》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013053073A1 (en) * | 2011-10-10 | 2013-04-18 | Huang Daiyong | Mannan oligosaccharide-based gastrointestinal tract health factor composition |
| CN105767596A (en) * | 2016-03-17 | 2016-07-20 | 江苏富裕达粮食制品股份有限公司 | Anti-stress enhancer for macrobrachium rosenbergii and application thereof |
| CN107232610A (en) * | 2017-05-25 | 2017-10-10 | 杭州特悘衡康生物科技有限公司 | A kind of carbohydrate composition of beta glucan containing yeast and its application |
| CN110250340A (en) * | 2019-07-18 | 2019-09-20 | 无锡中顺生物技术有限公司 | A kind of complex polysaccharide of aquatic products and its application |
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Application publication date: 20110216 |