CN101952298B - 用于过渡金属催化的交联偶合反应的配体及其使用方法 - Google Patents

用于过渡金属催化的交联偶合反应的配体及其使用方法 Download PDF

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CN101952298B
CN101952298B CN200880126921.5A CN200880126921A CN101952298B CN 101952298 B CN101952298 B CN 101952298B CN 200880126921 A CN200880126921 A CN 200880126921A CN 101952298 B CN101952298 B CN 101952298B
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CN101952298A (zh
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S·L·布赫瓦德
B·P·富斯
D·S·萨里
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Massachusetts Institute of Technology
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5022—Aromatic phosphines (P-C aromatic linkage)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
    • C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/006—Palladium compounds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN200880126921.5A 2007-12-12 2008-12-12 用于过渡金属催化的交联偶合反应的配体及其使用方法 Active CN101952298B (zh)

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US1317407P 2007-12-12 2007-12-12
US61/013174 2007-12-12
US8736808P 2008-08-08 2008-08-08
US61/087368 2008-08-08
PCT/US2008/086651 WO2009076622A2 (en) 2007-12-12 2008-12-12 Ligands for transition-metal-catalyzed cross-couplings, and methods of use thereof

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CN101952298B true CN101952298B (zh) 2015-06-17

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US (1) US7858784B2 (OSRAM)
EP (1) EP2231680B1 (OSRAM)
JP (1) JP5591714B2 (OSRAM)
CN (1) CN101952298B (OSRAM)
CA (1) CA2708369C (OSRAM)
WO (1) WO2009076622A2 (OSRAM)

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CN102241614B (zh) * 2011-05-10 2015-09-02 浙江建业化工股份有限公司 一种n-烃基取代酰胺化合物的合成方法
CN102516300A (zh) * 2011-11-09 2012-06-27 中山大学 一类膦配体及其对映体或消旋体及其制备方法
CN102557966A (zh) * 2011-12-23 2012-07-11 中国石油化工股份有限公司 一种制备防老剂dtpd的方法
WO2013159229A1 (en) * 2012-04-24 2013-10-31 Dalhousie University Silanyloxyaryl phosphine ligand and uses thereof in c-n cross-coupling
EP2859005B1 (en) 2012-06-08 2018-10-31 Massachusetts Institute of Technology Phosphine-ligated palladium sulfonate palladacycles
US9238665B2 (en) * 2012-07-06 2016-01-19 Sumitomo Chemical Company, Limited Method for producing aromatic compound
CN110003271B (zh) 2012-07-06 2022-05-03 住友化学株式会社 芳香族化合物的制备方法
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JP6123097B2 (ja) 2012-10-10 2017-05-10 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト チエノピリミジン化合物を製造するための方法
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WO2016094489A1 (en) 2014-12-10 2016-06-16 The Regents Of The University Of California Phosphorus ligands and methods of use
CN106588983B (zh) * 2015-10-14 2021-10-01 香港理工大学深圳研究院 咔唑基磷配体、及其制备方法和应用
CN105273006B (zh) * 2015-11-02 2017-09-19 盘锦格林凯默科技有限公司 2‑二环己基膦‑2,4,6‑三异丙基联苯的制备方法
US20170173569A1 (en) 2015-12-16 2017-06-22 Bruce H. Lipshutz Fe-ppm Pd, Cu and/or Ni Nanoparticle-Catalyzed Reactions in Water
WO2018081672A1 (en) 2016-10-31 2018-05-03 The Regents Of The University Of California Biaryl ligands for transition metal-catalyzed reactions
CN109956970A (zh) * 2017-12-26 2019-07-02 南开大学 联苯型三齿配体钌络合物及其制备方法和应用
CN110240616B (zh) 2018-03-07 2021-03-23 东莞市均成高新材料有限公司 三联芳单膦配体、它们的制备方法和在催化偶联反应中的用途
JP7041092B2 (ja) 2019-04-05 2022-03-23 日本化学工業株式会社 ビアリールホスフィンの製造方法
CN113019463B (zh) * 2021-05-25 2021-09-07 江苏欣诺科催化剂有限公司 钯复合催化剂及其制备方法和应用
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JP2011508726A (ja) 2011-03-17
CN101952298A (zh) 2011-01-19
US7858784B2 (en) 2010-12-28
CA2708369A1 (en) 2009-06-18
CA2708369C (en) 2017-04-04
US20090221820A1 (en) 2009-09-03
WO2009076622A3 (en) 2010-08-12
EP2231680A4 (en) 2012-05-30
JP5591714B2 (ja) 2014-09-17
EP2231680A2 (en) 2010-09-29
EP2231680B1 (en) 2018-03-28
WO2009076622A2 (en) 2009-06-18

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