CN101952241B - 治疗维生素b12缺乏的方法 - Google Patents

治疗维生素b12缺乏的方法 Download PDF

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Publication number
CN101952241B
CN101952241B CN200880119724.0A CN200880119724A CN101952241B CN 101952241 B CN101952241 B CN 101952241B CN 200880119724 A CN200880119724 A CN 200880119724A CN 101952241 B CN101952241 B CN 101952241B
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CN
China
Prior art keywords
vitamin
pharmaceutical composition
snac
tablet
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880119724.0A
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English (en)
Chinese (zh)
Other versions
CN101952241A (zh
Inventor
C·卡斯特里
L·克拉吉
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Emisphere Technologies Inc
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Emisphere Technologies Inc
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Application filed by Emisphere Technologies Inc filed Critical Emisphere Technologies Inc
Publication of CN101952241A publication Critical patent/CN101952241A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN200880119724.0A 2007-11-02 2008-10-31 治疗维生素b12缺乏的方法 Expired - Fee Related CN101952241B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US98489807P 2007-11-02 2007-11-02
US60/984,898 2007-11-02
US2010808P 2008-01-09 2008-01-09
US61/020,108 2008-01-09
US8356608P 2008-07-25 2008-07-25
US61/083,566 2008-07-25
PCT/US2008/082064 WO2009059188A1 (en) 2007-11-02 2008-10-31 Method of treating vitamin b12 deficiency

Publications (2)

Publication Number Publication Date
CN101952241A CN101952241A (zh) 2011-01-19
CN101952241B true CN101952241B (zh) 2014-06-11

Family

ID=40591491

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880119724.0A Expired - Fee Related CN101952241B (zh) 2007-11-02 2008-10-31 治疗维生素b12缺乏的方法

Country Status (18)

Country Link
US (3) US8022048B2 (https=)
EP (1) EP2215047B1 (https=)
JP (1) JP5555634B2 (https=)
KR (1) KR101344369B1 (https=)
CN (1) CN101952241B (https=)
AU (1) AU2008318423B2 (https=)
BR (1) BRPI0817396C8 (https=)
CA (1) CA2704780C (https=)
CL (1) CL2010000434A1 (https=)
CO (1) CO6280475A2 (https=)
DK (1) DK2215047T3 (https=)
ES (1) ES2443817T3 (https=)
MX (1) MX2010004716A (https=)
NZ (1) NZ585080A (https=)
PL (1) PL2215047T3 (https=)
PT (1) PT2215047E (https=)
RU (1) RU2469728C2 (https=)
WO (1) WO2009059188A1 (https=)

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CA2790708A1 (en) * 2010-02-24 2011-09-01 Emisphere Technologies, Inc. Oral b12 therapy
MX377589B (es) 2010-12-16 2025-03-10 Novo Nordisk As Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico.
RU2602601C2 (ru) 2011-04-12 2016-11-20 Ново Нордиск А/С Дважды ацилированные производные glp-1
US8805208B2 (en) * 2012-02-03 2014-08-12 Tyco Electronics Subsea Communications Llc System and method for polarization de-multiplexing in a coherent optical receiver
DK2827845T3 (en) 2012-03-22 2019-04-01 Novo Nordisk As COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF
EP3542790B1 (en) 2012-03-22 2023-09-13 Novo Nordisk A/S Compositions comprising a delivery agent and preparation thereof
CN104203266B (zh) 2012-03-22 2017-12-26 诺和诺德股份有限公司 Glp‑1肽组合物及其制备
JP6517690B2 (ja) 2012-06-20 2019-05-22 ノヴォ ノルディスク アー／エス ペプチド及び送達剤を含む錠剤製剤
US20140309270A1 (en) 2013-04-11 2014-10-16 Richard Louis Price Diagnosis and treatment of a form of autistic spectrum disorder
US10098848B2 (en) 2013-04-11 2018-10-16 Richard Louis Price Inositol-containing comestible units and methods of treatment using the same
US9211284B2 (en) 2013-04-11 2015-12-15 Richard Louis Price Diagnosis and treatment of P.R.I.C.E. syndrome
US9603812B2 (en) 2013-04-11 2017-03-28 Richard Louis Price Treatment of autistic spectrum disorder
US20170348417A1 (en) 2013-04-11 2017-12-07 Richard Louis Price Treatment of attention deficit disorders and associated symptoms
JP6672140B2 (ja) 2013-05-02 2020-03-25 ノヴォ ノルディスク アー／エス Ｇｌｐ−１化合物の経口投薬
EP3928776B1 (en) 2016-04-22 2025-11-12 Spoke Sciences, Inc. Fast-acting plant-based medicinal compounds and nutritional supplements
EA201892396A1 (ru) 2016-12-02 2019-04-30 Ресептор Лайф Сайенсиз, Инк. Быстродействующие растительные лекарственные соединения и биологически активные добавки
MX2020003330A (es) * 2017-10-05 2020-07-28 Receptor Holdings Inc Composiciones de hierbas con mejor biodisponibilidad.
CA3078549A1 (en) * 2017-10-05 2019-04-11 Receptor Holdings, Inc. Rapid onset and extended action plant-based and synthetic cannabinoid formulations
PL3746111T3 (pl) 2018-02-02 2024-01-15 Novo Nordisk A/S Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową
AU2019385420A1 (en) 2018-11-19 2021-07-08 Spoke Sciences, Inc. N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions

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US20060116334A1 (en) * 2004-12-01 2006-06-01 Curt Hendrix Folate based composition for treatment of the cardiovascular system

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US20050186267A1 (en) * 2002-09-13 2005-08-25 Thompson Diane O. Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin
US20060116334A1 (en) * 2004-12-01 2006-06-01 Curt Hendrix Folate based composition for treatment of the cardiovascular system

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Also Published As

Publication number Publication date
HK1146480A1 (en) 2011-06-10
RU2469728C2 (ru) 2012-12-20
CA2704780A1 (en) 2009-05-07
US8288360B2 (en) 2012-10-16
EP2215047B1 (en) 2013-11-20
BRPI0817396A2 (pt) 2015-04-07
US20100016255A1 (en) 2010-01-21
DK2215047T3 (da) 2014-02-03
CO6280475A2 (es) 2011-05-20
PT2215047E (pt) 2014-01-20
AU2008318423B2 (en) 2013-12-05
MX2010004716A (es) 2010-12-17
US20110293589A1 (en) 2011-12-01
JP5555634B2 (ja) 2014-07-23
ES2443817T3 (es) 2014-02-20
KR101344369B1 (ko) 2013-12-24
KR20100126263A (ko) 2010-12-01
WO2009059188A1 (en) 2009-05-07
BRPI0817396C8 (pt) 2021-05-25
PL2215047T3 (pl) 2014-05-30
AU2008318423A1 (en) 2009-05-07
US20130040910A1 (en) 2013-02-14
BRPI0817396B1 (pt) 2019-04-24
RU2010118423A (ru) 2011-12-10
NZ585080A (en) 2012-05-25
CL2010000434A1 (es) 2011-01-28
JP2011502997A (ja) 2011-01-27
EP2215047A1 (en) 2010-08-11
US8022048B2 (en) 2011-09-20
BRPI0817396B8 (pt) 2020-02-04
US8557792B2 (en) 2013-10-15
CN101952241A (zh) 2011-01-19
BRPI0817396C1 (pt) 2020-11-17
EP2215047A4 (en) 2010-11-10
CA2704780C (en) 2014-06-10

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Granted publication date: 20140611