CN101947099A - Integrated confocal microscopic rigid laryngoscope system - Google Patents
Integrated confocal microscopic rigid laryngoscope system Download PDFInfo
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- CN101947099A CN101947099A CN 201010288402 CN201010288402A CN101947099A CN 101947099 A CN101947099 A CN 101947099A CN 201010288402 CN201010288402 CN 201010288402 CN 201010288402 A CN201010288402 A CN 201010288402A CN 101947099 A CN101947099 A CN 101947099A
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Abstract
The invention belongs to the field of medical apparatuses and particularly discloses an integrated confocal microscopic rigid laryngoscope system, which comprises a rigid laryngoscope, wherein the rigid working end part of the rigid laryngoscope is provided with a confocal microscopic lens, a confocal laser head, a light guide optical fiber and an apparatus channel exit; the confocal microscopic lens and the confocal laser head are integrated on the rigid working end part; and the rigid laryngoscope is designed to be an integrated confocal microscopic rigid laryngoscope. In the integrated confocal microscopic rigid laryngoscope system, confocal microscopic technology and the rigid laryngoscope are combined effectively, the confocal microscopic lens and the confocal microscopic laser head are arranged in the structure of the rigid laryngoscope, the 448-nanometer blue laser beam emitted from the confocal microscopic laser head interacts with fluorescein sodium to amplify the suspicious lesions in the throat by over 1,000 times, and thus, a tool for performing real-time biopsy of throat mucosal lesions on an ultra microstructure is provided for doctors.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to the integrated confocal microscopy hard laryngoscope system of a kind of diagnosis and treatment laryngeal pathological process.
Prior art
Existing electron microscopic laryngoscope, the doctor can obtain the image effect of high-resolution and with the naked eye recognize some pathological changes of bottleneck throat, but be to use naked eyes to distinguish certain limitation is arranged, and can not see the ultrastructure of cell exactly.For the case that can not make a definite diagnosis, the doctor often will get biopsy at present.Get biopsy and observe pathological changes by the scope doctor exactly, by some pathological tissues of biopsy forceps gripping, deliver to Pathology Deparment, that takes off is organized in Pathology Deparment by multiple working procedure, examines under a microscope the form and the structure of cell at last, to determine the character of pathological changes.The whole long time of process need cost, be unfavorable for patient's timely diagnosis and treatment.
Because integrated confocal microscopy hard laryngoscope system combines burnt microtechnique of copolymerization and existing hard laryngoscope, can obtain the image of diseased region different depth level by focusing.Obtain dynamic physiology reaction in the 3-D solid structure of cell and the monitoring living cells by computer analysis and simulation, can to naked eyes the minute lesion that can not see diagnose, this is that traditional optical microscopy is not accomplished.Therefore, the integrated confocal microscopy hard laryngoscope system pool of developing that burnt microtechnique of a kind of copolymerization and existing hard laryngoscope combine is at the eyebrows and eyelashes.
Summary of the invention
The objective of the invention is to burnt microtechnique of copolymerization and hard laryngoscope are organically combined, by the Laser Scanning Confocal Microscope head throat's mucosa and pathological changes are carried out the microexamination diagnosis and treatment, a kind of integrated confocal microscopy hard laryngoscope system is proposed, this integrated confocal microscopy hard laryngoscope system throat's mucosa of biopsy in real time and pathological changes, can observe the macroscopical situation and the microcosmic situation of throat simultaneously, provide new platform for the doctor carries out real-time cell biopsy.
In order to reach above-mentioned technical purpose, the present invention is achieved through the following technical solutions:
Integrated confocal microscopy hard laryngoscope of the present invention system, comprise the burnt microlaryngoscope of integrated copolymerization, endoscopic cold light source main frame that is attached thereto and shooting main frame, and the shooting main frame monitor that links to each other with the shooting main frame, the burnt microlaryngoscope of described integrated copolymerization comprises hard work end, the cold light source input, data output end, instrument channel, described hard work end is provided with the Laser Scanning Confocal Microscope head, the confocal laser head, light-conductive optic fibre and instrument channel outlet, with the Laser Scanning Confocal Microscope head, the confocal laser head is integrated in hard work end the hard laryngoscope is designed to the burnt microlaryngoscope of integrated copolymerization, also be connected with the burnt micro-main frame of copolymerization on this integrated confocal microscopy hard laryngoscope, and focus on the burnt micro-monitor of copolymerization that micro-main frame links to each other together.
In the present invention, the diameter of described instrument channel is≤3.0mm, can allow the operating theater instruments of standard to enter throat and undergo surgery, and makes the burnt microlaryngoscope of integrated copolymerization not only have the function of diagnosis, also has the treatment function; Described hard work end diameter is smaller or equal to 10mm, and the end is smaller or equal to 200mm, and in addition, for fear of the damage mucosal tissue, blunt shape is processed in the burnt microlaryngoscope hard of integrated copolymerization work end tip portion.
In the present invention, it is the electronic CCD optical system of 1.5～3.0mm optical lens that its light path adopts diameter, and the CCD chip of electronic CCD optical system adopts size≤1/4 ", the CCD of at least 48 universal effect pixels, 100 ° of the angles of view or more than.
Further improvement as above-mentioned technology, the shooting center of described integrated confocal microscopy hard laryngoscope system connects a monitor, the burnt micro-main frame of copolymerization of described integrated confocal microscopy hard laryngoscope system has two kinds or above control model: first kind is to adopt touch monitor control model, realizes the burnt micro-functions such as unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording of copolymerization by the monitor with touch function; Second kind is to adopt the Keyboard Control pattern, connects keyboard by the burnt micro-main frame of copolymerization and controls, and realizes the burnt micro-functions such as unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording of copolymerization.
Compared with prior art, the invention has the beneficial effects as follows:
Integrated confocal microscopy hard laryngoscope of the present invention system, burnt microtechnique of copolymerization and hard laryngoscope are organically combined, under the effect of fluorescein sodium, the doctor presses close to throat by operating the burnt microlaryngoscope of integrated copolymerization, can be intracellular dynamically with 30 frame/seconds (fps) or above speed record, the burnt micro-main frame of copolymerization can be with 230fps or above speed photographic images, by integrated confocal microscopy hard laryngoscope system, the doctor can observe the macroscopical situation and the microcosmic situation of diseased region simultaneously, provides new platform for the doctor carries out real-time cell biopsy.
Description of drawings
Fig. 1 is an integrated confocal microscopy hard laryngoscope system schematic of the present invention.
Fig. 2 is the burnt microlaryngoscope structural representation of integrated copolymerization among the present invention.
Fig. 3 is the end view of the burnt microlaryngoscope of integrated copolymerization among the present invention.
Fig. 4 is the control mode sketch map one of integrated confocal microscopy hard laryngoscope of the present invention system.
Fig. 5 is the control mode sketch map two of integrated confocal microscopy hard laryngoscope of the present invention system.
Fig. 6 is the operation sketch map of integrated confocal microscopy hard laryngoscope of the present invention system.
The specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing:
As shown in Figure 1, integrated confocal microscopy hard laryngoscope of the present invention system comprises the burnt microlaryngoscope 1 of integrated copolymerization, bracing frame 8, light source main frame 2, shooting main frame 3, the burnt micro-main frame 4 of copolymerization, keyboard 5, the burnt micro-monitor 7 of shooting main frame monitor 6 and copolymerization is formed.
As shown in Figure 2, the burnt microlaryngoscope 1 of described integrated copolymerization comprises hard work end 11, cold light source joint 12, data output end 13, instrument channel 14, the diameter of described instrument channel 14 be≤3.0mm, can allow the operating theater instruments of standard to enter throat and undergo surgery, make the burnt microlaryngoscope of integrated copolymerization not only have the function of diagnosis, also have the treatment function; Described hard work end diameter is smaller or equal to 10mm, the end smaller or equal to 200mm. in addition, for fear of the damage mucosal tissue, blunt shape is processed in the burnt microlaryngoscope hard of integrated copolymerization work end tip portion.
In the present invention, the burnt microlaryngoscope 1 of described integrated copolymerization, its light path is that the employing diameter is the electronic CCD optical system of 1.5～3.0mm optical lens, the CCD chip of this electronic CCD optical system adopts size≤1/4 "; the CCD of at least 48 universal effect pixels, 100 ° of the angles of view or more than, described data output end 13 and hard work end 11 angles at 45; burnt microlaryngoscope 1 integral body of integrated copolymerization is gun type of gas burner, improves gripability and stability in the operative process effectively.
As shown in Figure 3, the first end of the hard work end 11 of the burnt microlaryngoscope 1 of described integrated copolymerization is provided with Laser Scanning Confocal Microscope head 131, confocal laser head 132, optical lens 133, light-conductive optic fibre 121 and instrument channel outlet 141.The burnt micro-main frame 4 of copolymerization can provide 1000 times or the above micro-function of scanning, focus on the keyboard 5 that micro-main frame 4 is connected together and carry out the burnt micro-control of copolymerization, function includes the burnt micro-unlatching switch of copolymerization at least, the freeze frame switch, amplify minification by-pass cock etc., focus on the monitor that micro-main frame 4 is connected together and can feed back all data parameters of the burnt microscan of copolymerization in real time, monitor its duty.
Fig. 4, Fig. 5 are the control mode sketch map of the burnt microlaryngoscope of integrated copolymerization of the present invention 1 system.The burnt micro-main frame 4 of copolymerization of the burnt microlaryngoscope of described integrated copolymerization 1 system provides two kinds or above control model: first kind is to adopt touch monitor control model, as shown in Figure 4, realize the burnt micro-functions such as unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording of copolymerization by monitor 71 with touch function; Second kind is to adopt the Keyboard Control pattern, as shown in Figure 5, connects keyboard 5 by the burnt micro-main frame 4 of copolymerization and controls, and realizes the burnt micro-functions such as unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording of copolymerization.
Fig. 6 is the operation sketch map of the burnt microlaryngoscope 1 of integrated copolymerization of the present invention.Carry out the confocal laser microscan, then before operation, the doctor need be to a certain amount of fluorescein sodium of patient infusion.In the art, bracing frame 8 is inserted in the patient oral cavity, feed the burnt microlaryngoscope of integrated copolymerization then and enter patient throat 9, under the effect of the 488nm blue laser beam that confocal laser head 132 sends, fluorescein sodium produces special image, image inputs to the burnt micro-main frame 4 of copolymerization via Laser Scanning Confocal Microscope head 131 to carry out Flame Image Process and makes 1000 times or above amplification demonstration, intracellular dynamically with 30fps or above speed record, with 230fps or above speed photographic images, mucosa or pathological changes to throat are carried out the diagnosis of microscopic level, help the doctor that pathological changes is made accurate judgement.
Claims (6)
1. integrated confocal microscopy hard laryngoscope system, comprise the hard laryngoscope, endoscopic cold light source main frame that is connected with the hard laryngoscope and shooting main frame, and the shooting main frame monitor that links to each other with the shooting main frame, described hard laryngoscope comprises hard work end, at least one instrument channel that is communicated with hard work end, cold light source input and data output end, it is characterized in that: described hard work end is provided with the Laser Scanning Confocal Microscope head, the confocal laser head, light-conductive optic fibre and instrument channel outlet, with the Laser Scanning Confocal Microscope head, the confocal laser head is integrated in hard work end the hard laryngoscope is designed to integrated confocal microscopy hard laryngoscope, also be connected with the burnt micro-main frame of copolymerization on this integrated confocal microscopy hard laryngoscope, and focus on the burnt micro-monitor of copolymerization that micro-main frame links to each other together.
2. integrated confocal microscopy hard laryngoscope according to claim 1 system is characterized in that: the diameter≤3.0mm of described instrument channel.
3. integrated confocal microscopy hard laryngoscope according to claim 1 and 2 system is characterized in that: described hard work end diameter≤10mm, hard work tip lengths≤200mm.
4. integrated confocal microscopy hard laryngoscope according to claim 3 system is characterized in that: described data output end and hard work end angle at 45.
5. integrated confocal microscopy hard laryngoscope according to claim 4 system, it is characterized in that: its light path adopts the electronic CCD optical system of diameter 1.5～3.0mm optical lens, the CCD chip of this electronic CCD optical system adopts size≤1/4 "; the CCD of at least 48 universal effect pixels, the angle of view 〉=100 °.
6. integrated confocal microscopy hard laryngoscope according to claim 1 system, it is characterized in that: the burnt micro-main frame of described copolymerization has two kinds or above control model: first kind is to adopt touch monitor control model, realizes the function of unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording that copolymerization Jiao is micro-by the monitor with touch function; Second kind is to adopt the Keyboard Control pattern, connects keyboard by the burnt micro-main frame of copolymerization and controls, and realizes the function of unlatching, freeze frame, the adjusting of amplification minification, grabgraf and video recording that copolymerization Jiao is micro-.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010288402 CN101947099A (en) | 2010-09-17 | 2010-09-17 | Integrated confocal microscopic rigid laryngoscope system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010288402 CN101947099A (en) | 2010-09-17 | 2010-09-17 | Integrated confocal microscopic rigid laryngoscope system |
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| CN101947099A true CN101947099A (en) | 2011-01-19 |
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| CN 201010288402 Pending CN101947099A (en) | 2010-09-17 | 2010-09-17 | Integrated confocal microscopic rigid laryngoscope system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147234A (en) * | 2015-11-02 | 2015-12-16 | 王文一 | Laryngeal surgical instrument |
| CN112545441A (en) * | 2020-11-30 | 2021-03-26 | 华中科技大学鄂州工业技术研究院 | Confocal micro-laryngoscope system with support limiting assembly |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101779972A (en) * | 2010-02-12 | 2010-07-21 | 广州市番禺区胆囊病研究所 | Confocal microscope and rigid choledochoscope integrated system |
| CN101803900A (en) * | 2010-02-12 | 2010-08-18 | 广州市番禺区胆囊病研究所 | Integrated confocal micro-rigid hysteroscope system |
| CN201831863U (en) * | 2010-09-17 | 2011-05-18 | 杨柳青 | Integrated confocal microscope hard laryngoscope system |
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2010
- 2010-09-17 CN CN 201010288402 patent/CN101947099A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101779972A (en) * | 2010-02-12 | 2010-07-21 | 广州市番禺区胆囊病研究所 | Confocal microscope and rigid choledochoscope integrated system |
| CN101803900A (en) * | 2010-02-12 | 2010-08-18 | 广州市番禺区胆囊病研究所 | Integrated confocal micro-rigid hysteroscope system |
| CN201831863U (en) * | 2010-09-17 | 2011-05-18 | 杨柳青 | Integrated confocal microscope hard laryngoscope system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147234A (en) * | 2015-11-02 | 2015-12-16 | 王文一 | Laryngeal surgical instrument |
| CN112545441A (en) * | 2020-11-30 | 2021-03-26 | 华中科技大学鄂州工业技术研究院 | Confocal micro-laryngoscope system with support limiting assembly |
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Application publication date: 20110119 |