A kind of cordate houttuynia additive for farm animal feed and preparation method thereof
Technical field
The present invention relates to a kind of feed addictive and preparation method thereof, especially a kind of cordate houttuynia additive for farm animal feed and preparation method thereof.
Background technology
At present, additive for farm animal feed has a variety of, much all is artificial synthetic medicines such as employing antibiotic.Artificial synthetic medicine is not a natural material, has side effect, does not meet the pollution-free food theory of rising day by day now.In addition, synthetic drug uses a ups and downs process is all arranged generally, though the initial stage have good curative effect, yet along with the residual accumulation constantly of medicine, curative effect also just constantly descends, even loses curative effect.Moreover present feed addictive generally has only simple function, or is purpose with the weightening finish, or is purpose with the diseases prevention, does not also have multi-functional feed addictive.
Cordate houttuynia is the medical practice confirmation medicine food dual purpose plant useful and harmless to human and livestock health through several thousand, have stronger antibiotic, antiviral, improve effect such as body's immunity, especially diseases such as the stomach of humans and animals, lung, intestines there is special efficacy, there is data to show, from cordate houttuynia, extracted a kind of cancer-resisting substance abroad, except that to cancer of the stomach effectively, also medium and advanced lung cancer, the carcinoma of the rectum etc. is had certain curative effect and corrective action.At present, adopted cordate houttuynia in some feed addictives, but the content of cordate houttuynia is few, only plays booster action, and do not have the auxiliary material of employing and its compatibility, excite and improve its effect.Therefore, adopt the do not increase weight dual-use function of diseases prevention of the feed addictive of cordate houttuynia at present.Chen Yanling (2008) report, with (1) Chinese bulbul, golden cypress, the capsule of weeping forsythia, the bark of ash, dandelion, Da Ye green grass or young crops, the root of herbaceous peony, the bighead atractylodes rhizome, rhizoma atractylodis, dried orange peel, Poria cocos, garden burnet, granatum etc., (2) Radix Angelicae Sinensis, Poria cocos, the Radix Astragali, the root of herbaceous peony, the bighead atractylodes rhizome, rhizoma atractylodis, dried orange peel, hawthorn, cordate houttuynia etc. are formed feed addictive, with control group (not adding feed addictive) weanling pig is fed contrast test, the compound Chinese herb group improves 12.07%, 23.14% than control group average daily gain respectively as a result, but prevention diarrhoea does not have significant difference.Liu Jiancheng etc. are respectively Chinese medicine additive group, antibacterials and short long agent control group with compositions such as Chinese medicine compound prescription cordate houttuynia, honeysuckle, the root of large-flowered skullcap, Poria cocos, Radix Angelicae Sinensis, Radix Glycyrrhizaes.Raising relatively through 114 days 4 stages, the result shows: in omnidistance feeding experiment, the daily gain of Chinese medicine compound prescription group pig has improved 3.52% than control group; Though the diarrhea rate comparison reduces by 28.5% according to (9.4%), also has 7.2%.Ma Hanli (2005) report, with preparation Chinese herbal feed additives such as cordate houttuynia, Poria cocos, hawthorn, contrast the weanling pig of feeding with antibiotic, the result shows, though Chinese herbal feed additive group diarrhea rate (3.57%), antibiotic group (6.7%) have reduced by 69% and 42% than control group (11.61%) respectively, diarrhea rate also has 3.57% and 6.7%.Wang Junhui (2007) is with cordate houttuynia, Astragalus Root P.E, virginiamycin and they are hybridly prepared into the compound houttuynin preparation and blank is fed the weanling pig contrast test, there were significant differences for the total augment weight of test group and average daily gain and control group as a result, though the diarrhea rate of compound houttuynin preparation group is minimum in all test group, improved 52.2% than control group, but diarrhea rate also has 17.5%.There is test to add confirm for milking sow every day by every 1kg body weight and feeds the incidence of disease that the 2g pine needle meal can make the white scour of piglet and reduce, reduce to 28% from 89%, but also have 28%; The pine needle meal test of feeding that foreign trade Ji Chang in Zhuhai City, Guangdong Province carries out, survivability of chicks bring up to 75% from 68%, but survival rate is less than 80%.In a word, from above recently relevant Chinese medicine compound prescription feed addictive test, though the cordate houttuynia composition that added the people in the additive does not all fully excite its consummating function of cordate houttuynia, its prevention diarrhea rate does not all reach more than 95%.
Summary of the invention
The present invention will solve the shortcoming of above-mentioned prior art, provides a kind of based on cordate houttuynia, not only can promote livestock and poultry weightening finish but also cordate houttuynia additive for farm animal feed that can diseases prevention and preparation method thereof.This additive is based on cordate houttuynia, is equipped with the Chinese medicine compound prescription additive of six kinds of Chinese medicines combinations such as pine needle meal, Radix Isatidis, the Radix Astragali, honeysuckle, dandelion, can give full play to multi-functional effects such as its multicomponent, multi-level, treating different diseases with same method, complementary length; And aboundresources such as main ingredient amount cordate houttuynia, pine needle, good and cheap, determined curative effect is again green non-pollution, safety, avirulent pure natural medical, is the additive for farm animal feed of high-quality, the market development prospect is very good.
The present invention solves the technical scheme that its technical problem adopts: this cordate houttuynia additive for farm animal feed, comprise cordate houttuynia, its component also comprises pine needle, Radix Isatidis, the Radix Astragali, honeysuckle, dandelion, and the weight proportion of each component is as follows: 25 parts~40 parts of cordate houttuynias, 20 parts~40 parts in pine needle, 10 parts~20 parts of Radix Isatidis, 10 parts~20 parts of the Radixs Astragali, 5 parts~10 parts of honeysuckles, 10 parts~20 parts of dandelions.
The preparation method of this above-mentioned cordate houttuynia additive for farm animal feed, with above-mentioned component, every sample mixes after pulverizing and wearing into fine powder in proportion, gets final product.After component was worn into fine powder, thickness was at 12 orders~100 orders.During mixing, use the double helix cone-type mixer, carry out abundant mixing, mixture homogeneity CV ≦ 5%.
This additive is that the main 6 flavor Chinese herbal medicines such as pine needle, the Radix Astragali, honeysuckle, Radix Isatidis, dandelion that are equipped with are formed with the cordate houttuynia, exhausted pure natural, ecosystem, green Chinese herbal medicine additive for farm animal feed without chemical extraction, wherein cordate houttuynia, the Radix Astragali, honeysuckle, Radix Isatidis, dandelion etc. are the main traditional Chinese medicinal materials assortments of the expressly definite birds flu-preventing of health ministry, first stream (swine flu), SARS etc. for 5 kinds.Cordate houttuynia is the medical practice confirmation medicine food dual purpose plant useful and harmless to human and livestock health through several thousand, have stronger antibiotic, antiviral, improve effect such as body's immunity, especially diseases such as the stomach of humans and animals, lung, intestines there is special efficacy, there is data to show, from cordate houttuynia, extracted a kind of cancer-resisting substance abroad, except that to cancer of the stomach effectively, also medium and advanced lung cancer, the carcinoma of the rectum etc. is had certain curative effect and corrective action.See all have heat-clearing toxin-expelling functions from honeysuckle, Radix Isatidis, the dandelion of compatibility, Radix Isatidis poison during based on pestilence, honeysuckle is based on wind-heat influenza, pestilence heating, erysipelas, dandelion is based on jaundice with damp-heat pathogen, pyogenic infections, hot eyes, have treating the same disease with different methods, multicomponent with the cordate houttuynia compatibility, harrow point more, the inferior effect of multilayer, make additive be difficult for producing drug resistance.The Radix Astragali, pine needle consolidate and set upright, liver protecting, growth promotion are grown (similar plants hormone) effect of etc.ing, just in time complement each other with compatibility such as cordate houttuynia, effect such as complementation shortcoming.And this greatest drawback of synthetic drug such as antibiotic just, synthetic drug uses a ups and downs process is all arranged generally, though the initial stage have good curative effect, yet along with the residual accumulation constantly of medicine, curative effect also just constantly descends, even loses curative effect.
Additive multifunctionality of the present invention, the one, trophism: the contained protein of Chinese herbal medicine, vitamin etc. are to the nutritious effect of animal body.The 2nd, improve non-specific immunity: as can obviously improve lgE in the blood, lgM content after taking the Radix Astragali, and the 3rd, produce hormone-like effect: adjust body metabolism, can promote the cells physiological metabolism, can promote the poultry growth with the Radix Astragali, pine needle as the Radix Astragali.The 4th, anti-stress effect: prolong the animal survival ability, improve tolerance, just rna content increases in the anoxic animal cardiac muscle.The 5th, antibiotic effect: Gram-positive and negative germ are all had inhibition and killing action as cordate houttuynia, Radix Isatidis, honeysuckle, dandelion etc.; Improve the phagocytic activity of zooblast, enhancing antibody forms; And anti-virus, fungi, protozoon and spirochaete infection in advance.The function of Chinese herb feed additives such as pine needle also has vitaminoid action, dual regulation and complex function, and can improve the feed palatability, increases appetite, promotes to digest and assimilate, the oxidation of anti-feed and going mouldy.
The mechanism of action 1 of additive of the present invention, available nutrient are analyzed cordate houttuynia and are contained decanoy acetaldehyde, methylnonanone, laurene, capraldehyde, capric acid, also contain active ingredients such as cordarine, isoquercitin; The main active ingredient of Radix Isatidis be (R, S)--accuse according to spring (C
5H
7NOS); The main active ingredient of the Radix Astragali is Astragaloside IV; Honeysuckle is mainly chlorogenic acid, galuteolin; Dandelion is mainly caffeic acid; Pine needle contains a large amount of active materials such as abundant vitamin, multiple pigment and carrotene, hormone and bacteriocidin etc., is the additional source of good vitamin and natural colouring matter.
2, to action principle (1) the antipathogen effect of animal body, cordate houttuynia, Radix Isatidis, honeysuckle etc. have some virus, bacterium kills inhibitory action more by force.(2) regulate the immunity of organism effect, the glycoside that contains in this compound additive, alkaloid, polysaccharide, organic acid, volatile ingredient etc. can activate the immune system of body, improve the body anti-infection ability.(3) contain nutritional labelings such as enriching amino acid, organic acid, vitamin and polysaccharide in this compound additive of trophism, can directly be absorbed by body.(4) hormone-like effect, the plant hormone that contains in the pine needle meal, thus promote the poultry growth.(5) anti-stress effect, the Radix Astragali etc. have anti-stress effect, and can reduce the infringement that stress reaction causes body.(6) promote the effect of body metabolism, this additive is to improve the metabolic rate of body dry, and organic metabolism rate and apparent nitrogen stay rate etc., and can improve the concentration of materials such as protein in the blood, trace element.
The effect that the present invention is useful is: (1) has special efficacy to the common diarrhoeal diseases of livestock and poultry, and the prevention protective rate reaches more than 99%, and the death rate is zero; (2) the omnidistance average daily gain 0.74kg that feeds of live pig improves 7.2% than blank group 0.69 kg, and feed conversion rate improves more than 9.7%.(3) the average every plumage daily gain 43.7g of fryer improves 5.3% than blank group 41.5 g, and feed conversion rate improves 5.9%.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1: the weight proportion of feed addictive component is as follows: cordate houttuynia 25 grams, pine needle 20 grams, Radix Isatidis 10 grams, the Radix Astragali 10 grams, honeysuckle 5 grams, dandelion 10 grams.Above Chinese medicine is dry product.
The preparation method is as follows: with above Chinese medicine, get every sample pulverize wear into fine powder (requiring thickness) between the 12-100 order after, carry out abundant mixing (mixture homogeneity CV ≦ 5%) with the double helix cone-type mixer in proportion.During use, with fine powder additive of the present invention by 2-5% with can feed after animal and fowl fodder (daily ration) evenly mixes with feed processor group FSP50-34.
Embodiment 2: the weight proportion of feed addictive component is as follows: cordate houttuynia 30 grams, pine needle 30 grams, Radix Isatidis 15 grams, the Radix Astragali 15 grams, honeysuckle 7 grams, dandelion 10 grams.
Embodiment 3: the weight proportion of feed addictive component is as follows: cordate houttuynia 40 grams, pine needle 40 grams, Radix Isatidis 20 grams, the Radix Astragali 20 grams, honeysuckle 10 grams, dandelion 20 grams.
The contrast situation of additive of the present invention and other several frequently seen additive
1, cordate houttuynia compound feed additive and other common feed addictive are fattened comparison on the performance pig
Test method: the large-scale pig farm in the Lishui, select 30 age in days weanling pigs, 90 of " long white " pork pigs that a number equates, body weight is suitable, parity is close are divided into 6 groups at random by the hurdle, 15 every group.The 1st group is the cordate houttuynia compound additive; The 2nd group is the pine needle meal additive; The 3rd group is existing " Taihu Lake 3 is good " feed addictive commonly used; The 4th group (not containing cordate houttuynia) " big porker looses " additive (by paulownia leaves, fortune paulownia flower, black soya bean, fleece-flower root proportion of composing 5:4:2:1); The 5th group is antibiotics additive such as aureomycin etc.; The 6th group of not doping of basal diet organized in contrast.Method for breeding is raised routinely, carries out omnidistance observed and recorded by 130 days that deliver for sale since 30 age in days weanling pigs.The result sees following table for details.
Several additives of table 1 are fattened performance comparative measurements result (unit: head, kg, sky, %) pig
Group |
Number |
Fate |
Starting weight |
The end is heavy |
Total augment weight |
Average daily weightening finish |
Total feed consumption |
Feedstuff-meat ratio |
Diarrhea rate |
1
|
15
|
130
|
121.2
|
1555.8
|
1434.6
|
0.74
|
3859.0
|
2.69:1
|
0
|
2
|
15
|
130
|
120.6
|
1523.7
|
1403.1
|
0.72
|
3928.7
|
2.80:1
|
13.3
|
3
|
15
|
130
|
122.1
|
1543.1
|
1421.0
|
0.73
|
3836.7
|
2.70:1
|
6.0
|
4
|
15
|
130
|
121.5
|
1555.9
|
1434.4
|
0.74
|
3887.2
|
2.71:1
|
20.0
|
5
|
15
|
130
|
120.7
|
1520.3
|
1399.6
|
0.72
|
3932.9
|
2.81:1
|
33.3
|
6
|
15
|
130
|
121.4
|
1480.2
|
1351.3
|
0.69
|
3988.8
|
2.95:1
|
46.7
|
2, cordate houttuynia compound additive anti-diarrhoea of feed interpolation in the omnidistance breed of pig is used
For determining the anti-diarrhoea of this additive effect, large-scale pig farm enlarges contrast test in the Lishui, till from beginning behind the sows farrowing pig to delivering for sale, add nursing with 4%, 3.5%, 3%, 3% ratio respectively in sow in lactation, weanling pig, middle pig, hog grower feed, compare with conventional (not adding this additive) nursing, about every group 500, carry out omnidistance observed and recorded, the result is as follows:
The anti-diarrhoea of table 2 present embodiment additive comparative test result (unit: head, sky, %)
Group |
Number |
Fate |
The diarrhoea number |
Diarrhea rate |
Death toll |
The death rate |
1 interpolation group |
505 |
160 |
5 |
1.0 |
0 |
0 |
2 control groups (not adding) |
498 |
160 |
225 |
41.2 |
13 |
2.6 |
3, the cordate houttuynia compound additive adds diseases prevention and gaining effect investigation on fryer is cultured
Table 3 broiler fodder adds present embodiment protection effect (unit: plumage, sky, %)
Group |
The plumage number |
Fate |
Morbidity number (diarrhoea number) |
Death toll (diarrhoea) |
The death rate (diarrhoea) |
Incubation rate |
1 interpolation group |
500 |
49 |
35(5) |
10(0) |
2.0(0) |
99.6 |
2 control groups (not adding) |
500 |
49 |
318(123) |
35(25) |
7.0(5.0) |
93.0 |
Table 4 broiler fodder adds present embodiment weightening finish and food conversion effect
Group |
Average feed consumption rate (g/ plumage) |
Average weight gain (g/ plumage) |
Feedstuff-meat ratio |
Average daily gain (g/ plumage, day) |
1 interpolation group |
5150 |
2139 |
2.41:1 |
43.7 |
2 control groups |
5199 |
2033 |
2.56:1 |
41.5 |
Though the present invention is described by the reference preferred embodiment,, those skilled in the art should understand, and in the scope of claims, can do the various variation on form and the details.