CN101896856B - 用于光学层析成像的景深扩展 - Google Patents

用于光学层析成像的景深扩展 Download PDF

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CN101896856B
CN101896856B CN2008801200775A CN200880120077A CN101896856B CN 101896856 B CN101896856 B CN 101896856B CN 2008801200775 A CN2008801200775 A CN 2008801200775A CN 200880120077 A CN200880120077 A CN 200880120077A CN 101896856 B CN101896856 B CN 101896856B
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detector
interest
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lens
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CN101896856A (zh
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理查德·J·拉恩
约·W·哈延加
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VisionGate Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle

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  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
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CN2008801200775A 2007-10-22 2008-10-22 用于光学层析成像的景深扩展 Expired - Fee Related CN101896856B (zh)

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US11/876,658 2007-10-22
US11/876,658 US7787112B2 (en) 2007-10-22 2007-10-22 Depth of field extension for optical tomography
PCT/US2008/080726 WO2009055429A1 (en) 2007-10-22 2008-10-22 Depth of field extension for optical tomography

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CN101896856B true CN101896856B (zh) 2013-02-13

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US (2) US7787112B2 (enExample)
JP (1) JP2011503530A (enExample)
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WO (1) WO2009055429A1 (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008129541A2 (en) * 2007-04-19 2008-10-30 Ramot At Tel-Aviv University Ltd Optical imaging system with an extended depth-of-field and method for designing an optical imaging system
US11792538B2 (en) 2008-05-20 2023-10-17 Adeia Imaging Llc Capturing and processing of images including occlusions focused on an image sensor by a lens stack array
US8866920B2 (en) 2008-05-20 2014-10-21 Pelican Imaging Corporation Capturing and processing of images using monolithic camera array with heterogeneous imagers
WO2010044870A1 (en) 2008-10-14 2010-04-22 The Burnham Institute For Medical Research Automated scanning cytometry using chromatic aberration for multiplanar image acquisition
US8155420B2 (en) * 2009-05-21 2012-04-10 Visiongate, Inc System and method for detecting poor quality in 3D reconstructions
US8514491B2 (en) 2009-11-20 2013-08-20 Pelican Imaging Corporation Capturing and processing of images using monolithic camera array with heterogeneous imagers
US8860948B2 (en) * 2010-01-22 2014-10-14 Ben Gurion University of the Negev Research and Development Authority Ltd.; Bar Ilan University High resolution extended depth of field optical coherence tomography
WO2011097616A2 (en) * 2010-02-08 2011-08-11 Cornell University Fluorescence collection objective optical system and method
CN102144927B (zh) * 2010-02-10 2012-12-12 清华大学 基于运动补偿的ct设备和方法
BR112013000874A2 (pt) * 2010-07-16 2016-05-17 3M Innovative Properties Co sistema de inspeção de foco automático de alta resolução
US20140192238A1 (en) * 2010-10-24 2014-07-10 Linx Computational Imaging Ltd. System and Method for Imaging and Image Processing
US8878950B2 (en) 2010-12-14 2014-11-04 Pelican Imaging Corporation Systems and methods for synthesizing high resolution images using super-resolution processes
US9063074B2 (en) 2010-12-30 2015-06-23 Empire Technology Development Llc Analyzing tissue morphology in three dimensions
WO2012090035A1 (en) * 2010-12-30 2012-07-05 Empire Technology Development Llc Spectral analysis of tissue morphology in three dimensions
DE102011006033B4 (de) * 2011-03-24 2015-11-19 Pamas Partikelmess- und Analysesysteme GmbH Messvorrichtung zur Detektierung der Größe von Partikeln in einem strömenden Medium und Verfahren hierfür
CN102735609A (zh) * 2011-03-31 2012-10-17 西门子公司 一种体液成像系统、方法及景深扩展成像装置
CN102314683B (zh) * 2011-07-15 2013-01-16 清华大学 一种非平面图像传感器的计算成像方法和成像装置
US8761333B2 (en) 2011-08-12 2014-06-24 General Electric Company Low resolution scintillating array for CT imaging and method of implementing same
US8942341B2 (en) 2011-09-01 2015-01-27 General Electric Company Method of dose reduction for CT imaging and apparatus for implementing same
CN104081414B (zh) 2011-09-28 2017-08-01 Fotonation开曼有限公司 用于编码和解码光场图像文件的系统及方法
US10001622B2 (en) 2011-10-25 2018-06-19 Sanford Burnham Medical Research Institute Multifunction autofocus system and method for automated microscopy
US9961326B2 (en) * 2012-01-09 2018-05-01 Kla-Tencor Corporation Stereo extended depth of focus
WO2013126578A1 (en) 2012-02-21 2013-08-29 Pelican Imaging Corporation Systems and methods for the manipulation of captured light field image data
US9575304B2 (en) * 2012-06-25 2017-02-21 Huron Technologies International Inc. Pathology slide scanners for fluorescence and brightfield imaging and method of operation
US9100635B2 (en) 2012-06-28 2015-08-04 Pelican Imaging Corporation Systems and methods for detecting defective camera arrays and optic arrays
US20140002674A1 (en) * 2012-06-30 2014-01-02 Pelican Imaging Corporation Systems and Methods for Manufacturing Camera Modules Using Active Alignment of Lens Stack Arrays and Sensors
AU2013305770A1 (en) 2012-08-21 2015-02-26 Pelican Imaging Corporation Systems and methods for parallax detection and correction in images captured using array cameras
EP2888698A4 (en) 2012-08-23 2016-06-29 Pelican Imaging Corp PROPERTY-BASED HIGH-RESOLUTION MOTION ESTIMATION FROM LOW-RESOLUTION IMAGES RECORDED WITH AN ARRAY SOURCE
US20140092281A1 (en) 2012-09-28 2014-04-03 Pelican Imaging Corporation Generating Images from Light Fields Utilizing Virtual Viewpoints
CN102980875B (zh) * 2012-11-19 2015-04-22 深圳大学 大景深三维纳米分辨成像方法、光学组件及成像系统
CN102973246B (zh) * 2012-12-03 2014-12-03 中国科学院自动化研究所 自动处理景深的光学投影断层成像方法
US8866912B2 (en) 2013-03-10 2014-10-21 Pelican Imaging Corporation System and methods for calibration of an array camera using a single captured image
US9124831B2 (en) 2013-03-13 2015-09-01 Pelican Imaging Corporation System and methods for calibration of an array camera
US9578259B2 (en) 2013-03-14 2017-02-21 Fotonation Cayman Limited Systems and methods for reducing motion blur in images or video in ultra low light with array cameras
WO2014153098A1 (en) 2013-03-14 2014-09-25 Pelican Imaging Corporation Photmetric normalization in array cameras
US9438888B2 (en) 2013-03-15 2016-09-06 Pelican Imaging Corporation Systems and methods for stereo imaging with camera arrays
US9497429B2 (en) 2013-03-15 2016-11-15 Pelican Imaging Corporation Extended color processing on pelican array cameras
US10122993B2 (en) 2013-03-15 2018-11-06 Fotonation Limited Autofocus system for a conventional camera that uses depth information from an array camera
US9679360B2 (en) * 2013-05-10 2017-06-13 Trustees Of Princeton University High-resolution light-field imaging
WO2015048694A2 (en) 2013-09-27 2015-04-02 Pelican Imaging Corporation Systems and methods for depth-assisted perspective distortion correction
TWI508526B (zh) * 2013-10-01 2015-11-11 Wistron Corp 產生視角平移影像之方法及其可攜式電子設備
US10119808B2 (en) 2013-11-18 2018-11-06 Fotonation Limited Systems and methods for estimating depth from projected texture using camera arrays
US9456134B2 (en) 2013-11-26 2016-09-27 Pelican Imaging Corporation Array camera configurations incorporating constituent array cameras and constituent cameras
US9791705B1 (en) 2013-12-31 2017-10-17 Wavefront Research, Inc. Common aperture optical relay system
CN106605164B (zh) 2014-03-04 2020-04-24 诺瓦达克技术公司 用于宽带成像的中继透镜系统
WO2015134996A1 (en) 2014-03-07 2015-09-11 Pelican Imaging Corporation System and methods for depth regularization and semiautomatic interactive matting using rgb-d images
DE102014105759A1 (de) * 2014-04-24 2015-10-29 Sick Ag Kamera und Verfahren zur Erfassung eines bewegten Stroms von Objekten
GB2527359B (en) * 2014-06-20 2020-05-27 Lightpoint Medical Ltd Method and apparatus for imaging of low radiance objects
CN104224127A (zh) * 2014-09-17 2014-12-24 西安电子科技大学 基于相机阵列的光学投影断层成像装置及方法
CN113256730B (zh) 2014-09-29 2023-09-05 快图有限公司 用于阵列相机的动态校准的系统和方法
WO2016071020A1 (en) * 2014-11-06 2016-05-12 Sony Corporation Imaging system including lens with longitudinal chromatic aberration, endoscope and imaging method
US9706094B2 (en) 2014-12-05 2017-07-11 National Security Technologies, Llc Hyperchromatic lens for recording time-resolved phenomena
US9989773B2 (en) * 2015-03-30 2018-06-05 Novadaq Technologies, Inc. Multi-channel wide field imaging system and optical system for use therein
US9552961B2 (en) 2015-04-10 2017-01-24 International Business Machines Corporation Scanning transmission electron microscope having multiple beams and post-detection image correction
CN104865195B (zh) * 2015-05-04 2018-02-02 中国科学院自动化研究所 光学投影断层成像的检测方法
US10408676B2 (en) 2015-10-01 2019-09-10 Mission Support and Test Services, LLC Long-pulse-width variable-wavelength chirped pulse generator and method
US11069054B2 (en) 2015-12-30 2021-07-20 Visiongate, Inc. System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy
WO2017180513A1 (en) * 2016-04-11 2017-10-19 The Regents Of The University Of California Real-time, parallel x-ray tomosynthesis
CN107454377B (zh) * 2016-05-31 2019-08-02 深圳市微付充科技有限公司 一种利用相机进行三维成像的算法和系统
US10627310B2 (en) * 2016-10-04 2020-04-21 LiFodas Imaging system for multi-fiber connector inspection
FI20175410A1 (fi) * 2017-05-08 2018-11-09 Grundium Oy Laite ja menetelmä mikroskooppileikkeiden skannaamiseksi
US10445886B2 (en) * 2017-05-30 2019-10-15 General Electric Company Motion-gated medical imaging
CN111527397B (zh) 2017-11-09 2023-11-17 逆转光子公司 红外ir成像系统及其光学窗口遮蔽检测方法
CN108020509A (zh) * 2017-12-12 2018-05-11 佛山科学技术学院 一种光学投影层析成像的方法及其装置
CN108459417B (zh) * 2018-02-05 2020-06-26 华侨大学 一种单目窄带多光谱立体视觉系统及其使用方法
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US10659751B1 (en) * 2018-12-14 2020-05-19 Lyft Inc. Multichannel, multi-polarization imaging for improved perception
US12313627B2 (en) 2019-05-01 2025-05-27 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
WO2021055585A1 (en) 2019-09-17 2021-03-25 Boston Polarimetrics, Inc. Systems and methods for surface modeling using polarization cues
CN114766003B (zh) 2019-10-07 2024-03-26 波士顿偏振测定公司 用于利用偏振增强传感器系统和成像系统的系统和方法
WO2021108002A1 (en) 2019-11-30 2021-06-03 Boston Polarimetrics, Inc. Systems and methods for transparent object segmentation using polarization cues
CN113037212B (zh) * 2019-12-05 2022-10-18 致茂电子(苏州)有限公司 光电组件特性测量装置
US11060138B1 (en) * 2020-01-17 2021-07-13 Element Biosciences, Inc. Nucleic acid sequencing systems
CN115552486A (zh) 2020-01-29 2022-12-30 因思创新有限责任公司 用于表征物体姿态检测和测量系统的系统和方法
CN115428028A (zh) 2020-01-30 2022-12-02 因思创新有限责任公司 用于合成用于在包括偏振图像的不同成像模态下训练统计模型的数据的系统和方法
CN111505819B (zh) * 2020-05-21 2022-04-05 杨星瑶 显微仪器和利用数字序列图像进行重复定位与测量的方法
WO2021243088A1 (en) 2020-05-27 2021-12-02 Boston Polarimetrics, Inc. Multi-aperture polarization optical systems using beam splitters
CN111679422B (zh) * 2020-06-09 2023-11-03 腾讯科技（深圳）有限公司 显微镜、图像处理系统及图像处理方法
EP4211508B1 (en) * 2020-09-14 2025-11-26 Singular Genomics Systems, Inc. Methods and systems for multidimensional imaging
US11587246B2 (en) * 2020-10-30 2023-02-21 Mitutoyo Corporation Metrology system with projected pattern for points-from-focus type processes
US12020455B2 (en) 2021-03-10 2024-06-25 Intrinsic Innovation Llc Systems and methods for high dynamic range image reconstruction
US12069227B2 (en) 2021-03-10 2024-08-20 Intrinsic Innovation Llc Multi-modal and multi-spectral stereo camera arrays
US11290658B1 (en) 2021-04-15 2022-03-29 Boston Polarimetrics, Inc. Systems and methods for camera exposure control
US11954886B2 (en) 2021-04-15 2024-04-09 Intrinsic Innovation Llc Systems and methods for six-degree of freedom pose estimation of deformable objects
US12067746B2 (en) 2021-05-07 2024-08-20 Intrinsic Innovation Llc Systems and methods for using computer vision to pick up small objects
US12175741B2 (en) 2021-06-22 2024-12-24 Intrinsic Innovation Llc Systems and methods for a vision guided end effector
US12340538B2 (en) 2021-06-25 2025-06-24 Intrinsic Innovation Llc Systems and methods for generating and using visual datasets for training computer vision models
US12172310B2 (en) 2021-06-29 2024-12-24 Intrinsic Innovation Llc Systems and methods for picking objects using 3-D geometry and segmentation
US11689813B2 (en) 2021-07-01 2023-06-27 Intrinsic Innovation Llc Systems and methods for high dynamic range imaging using crossed polarizers
IL310281A (en) 2021-07-21 2024-03-01 Element Biosciences Inc Optical systems for nucleic acid sequencing and methods thereof
US12293535B2 (en) 2021-08-03 2025-05-06 Intrinsic Innovation Llc Systems and methods for training pose estimators in computer vision
CN118233617B (zh) * 2024-05-21 2024-08-27 浙江华诺康科技有限公司 一种双目成像设备的调节方法、装置和计算机设备

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485413B1 (en) * 1991-04-29 2002-11-26 The General Hospital Corporation Methods and apparatus for forward-directed optical scanning instruments
CN1383785A (zh) * 2002-06-14 2002-12-11 清华大学 一种带有自适应光程调节装置的光学相干层析成像系统
US6725073B1 (en) * 1999-08-17 2004-04-20 Board Of Regents, The University Of Texas System Methods for noninvasive analyte sensing
CN1875242A (zh) * 2003-10-27 2006-12-06 通用医疗公司 用于使用频域干涉测量法进行光学成像的方法和设备

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470373A (en) 1966-10-18 1969-09-30 Litton Systems Inc Method for analysis and identification of biologic entities by phosphorescence
US3497690A (en) 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
US3598471A (en) 1968-11-22 1971-08-10 Corning Glass Works Optical contrast enhancement system
US3657537A (en) 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
US3748468A (en) 1971-12-22 1973-07-24 Gen Electric Automatic electron microscope field counter
US3999047A (en) 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US3833762A (en) 1973-06-04 1974-09-03 Rockwell International Corp Solid state integrating, image motion compensating imager
US4200353A (en) 1974-06-05 1980-04-29 Robert Hoffman Modulation contrast microscope with three regions
US3960449A (en) 1975-06-05 1976-06-01 The Board Of Trustees Of Leland Stanford Junior University Measurement of angular dependence of scattered light in a flowing stream
US4081277A (en) 1976-10-08 1978-03-28 Eastman Kodak Company Method for making a solid-state color imaging device having an integral color filter and the device
US4175860A (en) 1977-05-31 1979-11-27 Rush-Presbyterian-St. Luke's Medical Center Dual resolution method and apparatus for use in automated classification of pap smear and other samples
US4183623A (en) 1977-10-11 1980-01-15 Haines Kenneth A Tomographic cross-sectional imaging using incoherent optical processing
US4293221A (en) 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4360885A (en) 1980-01-02 1982-11-23 Edgar Albert D Micro-optical tomography
DE3424108A1 (de) 1984-06-29 1986-01-09 Bernhard Prof. Dr.-Ing. 4300 Essen Schrader Probenanordnung zur spektrometrie, verfahren zur messung von lumineszenz und streuung und verwendung der probenanordnung
US4702598A (en) 1985-02-25 1987-10-27 Research Corporation Flow cytometer
JPS61275813A (ja) * 1985-05-31 1986-12-05 Nippon Kogaku Kk <Nikon> 高倍率顕微鏡対物レンズ
US5281517A (en) 1985-11-04 1994-01-25 Cell Analysis Systems, Inc. Methods for immunoploidy analysis
US4873653A (en) 1986-04-09 1989-10-10 Carl-Zeiss-Stiftung Microscope system for providing three-dimensional resolution
US4858128A (en) 1986-08-11 1989-08-15 General Electric Company View-to-view image correction for object motion
US4891829A (en) 1986-11-19 1990-01-02 Exxon Research And Engineering Company Method and apparatus for utilizing an electro-optic detector in a microtomography system
DE3905619C2 (de) 1988-02-23 2000-04-13 Olympus Optical Co Bildeingabe-/Ausgabevorrichtung
JPH0285747A (ja) * 1988-09-21 1990-03-27 Shimadzu Corp 断層像再構成装置
US5141609A (en) 1990-11-16 1992-08-25 The Trustees Of The Leland Stanford Junior University Method and device employing time-delayed integration for detecting sample components after separation
JPH0667095A (ja) * 1990-12-07 1994-03-11 Olympus Optical Co Ltd 走査型レーザ顕微鏡
US6134003A (en) 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US6111645A (en) 1991-04-29 2000-08-29 Massachusetts Institute Of Technology Grating based phase control optical delay line
US5956355A (en) 1991-04-29 1999-09-21 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a rapidly frequency-tuned laser
DE69227902T3 (de) 1991-04-29 2010-04-22 Massachusetts Institute Of Technology, Cambridge Vorrichtung für optische abbildung und messung
US6501551B1 (en) 1991-04-29 2002-12-31 Massachusetts Institute Of Technology Fiber optic imaging endoscope interferometer with at least one faraday rotator
US6564087B1 (en) 1991-04-29 2003-05-13 Massachusetts Institute Of Technology Fiber optic needle probes for optical coherence tomography imaging
JPH04337446A (ja) 1991-05-15 1992-11-25 Hitachi Ltd 微粒子計測方法、定量方法および微粒子計測装置
US5548395A (en) 1991-09-20 1996-08-20 Toa Medical Electronics Co., Ltd. Particle analyzer
US5241523A (en) * 1991-12-05 1993-08-31 Eastman Kodak Company Polarization-based auto-focus apparatus
US5333164A (en) 1991-12-11 1994-07-26 General Electric Company Method and apparatus for acquiring and processing only a necessary volume of radon data consistent with the overall shape of the object for efficient three dimensional image reconstruction
GB9218482D0 (en) 1992-09-01 1992-10-14 Dixon Arthur E Apparatus and method for scanning laser imaging of macroscopic samples
US5668887A (en) 1992-05-29 1997-09-16 Eastman Kodak Company Coating density analyzer and method using non-synchronous TDI camera
JP3327948B2 (ja) 1992-06-09 2002-09-24 オリンパス光学工業株式会社 光学像再構成装置
US5390226A (en) 1992-07-02 1995-02-14 General Electric Company Method and apparatus for pre-processing cone beam projection data for exact three dimensional computer tomographic image reconstruction of a portion of an object
US5312535A (en) 1992-07-17 1994-05-17 Beckman Instruments, Inc. Capillary electrophoresis detection
DE69333642T2 (de) 1992-07-31 2005-10-06 Fuji Photo Film Co., Ltd., Minami-Ashigara Verfahren und Vorrichtung zur Gewinnung dreidimensionaler Information von Proben
US6159686A (en) 1992-09-14 2000-12-12 Sri International Up-converting reporters for biological and other assays
US6026174A (en) 1992-10-14 2000-02-15 Accumed International, Inc. System and method for automatically detecting malignant cells and cells having malignancy-associated changes
US5402460A (en) 1993-08-02 1995-03-28 University Of Washington Three-dimensional microtomographic analysis system
JPH07120401A (ja) * 1993-09-03 1995-05-12 Olympus Optical Co Ltd 透明物体内の気泡検出装置
US6215587B1 (en) 1994-02-14 2001-04-10 Robert R. Alfano Microscope imaging inside highly scattering media
JPH07286953A (ja) 1994-04-19 1995-10-31 Toa Medical Electronics Co Ltd イメージングフローサイトメータ
WO1996009594A1 (en) 1994-09-20 1996-03-28 Neopath, Inc. Apparatus for automated identification of thick cell groupings on a biological specimen
US5552605A (en) 1994-11-18 1996-09-03 Picker International, Inc. Motion correction based on reprojection data
US5539800A (en) 1995-03-24 1996-07-23 The Regents Of The University Of California, Office Of Technology Transfer Pseudolocal tomography
US5710429A (en) 1995-04-06 1998-01-20 Alfano; Robert R. Ultrafast optical imaging of objects in or behind scattering media
US5582705A (en) 1995-05-19 1996-12-10 Iowa State University Research Foundation, Inc. Multiplexed capillary electrophoresis system
US6252979B1 (en) 1995-06-07 2001-06-26 Tripath Imaging, Inc. Interactive method and apparatus for sorting biological specimens
WO1997001167A1 (en) 1995-06-21 1997-01-09 Massachusetts Institute Of Technology Apparatus and method for accessing data on multilayered optical media
AU7386496A (en) 1995-10-02 1997-04-28 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The An epithelial protein and dna thereof for use in early cancer detection
FI97665C (fi) 1995-11-21 1997-01-27 Planmed Oy Menetelmät ja laitteet kohteen kuvantamisessa
US6165734A (en) 1995-12-12 2000-12-26 Applied Spectral Imaging Ltd. In-situ method of analyzing cells
FR2743462B1 (fr) 1996-01-04 1998-01-30 Commissariat Energie Atomique Dispositif de lecture de barrettes de detecteurs avec effet tdi
JPH09247545A (ja) 1996-03-11 1997-09-19 Matsushita Electric Ind Co Ltd スキャナ型電子カメラ
US6078681A (en) 1996-03-18 2000-06-20 Marine Biological Laboratory Analytical imaging system and process
JP3640461B2 (ja) 1996-04-03 2005-04-20 シスメックス株式会社 粒子分析装置
US6038067A (en) 1996-05-23 2000-03-14 The Regents Of The University Of California Scanning computed confocal imager
US5880838A (en) 1996-06-05 1999-03-09 California Institute Of California System and method for optically measuring a structure
US5915048A (en) 1996-06-05 1999-06-22 Zetetic Institute Method and apparatus for discriminating in-focus images from out-of-focus light signals from background and foreground light sources
US5673300A (en) 1996-06-11 1997-09-30 Wisconsin Alumni Research Foundation Method of registering a radiation treatment plan to a patient
US6047080A (en) 1996-06-19 2000-04-04 Arch Development Corporation Method and apparatus for three-dimensional reconstruction of coronary vessels from angiographic images
US6130958A (en) 1996-11-29 2000-10-10 Imaging Diagnostic Systems, Inc. Method for reconstructing the image of an object scanned with a laser imaging apparatus
DE19701036A1 (de) 1997-01-15 1998-07-16 Philips Patentverwaltung MR-Verfahren zur bildgestützten Überwachung der Verschiebung eines Objektes und MR-Anordnung zur Durchführung des Verfahrens
US5760901A (en) 1997-01-28 1998-06-02 Zetetic Institute Method and apparatus for confocal interference microscopy with background amplitude reduction and compensation
US6091983A (en) 1997-02-07 2000-07-18 Alfano; Robert R. Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents
JPH10260131A (ja) 1997-03-19 1998-09-29 Seitai Hikarijoho Kenkyusho:Kk 光計測装置
DE19714221A1 (de) 1997-04-07 1998-10-08 Zeiss Carl Fa Konfokales Mikroskop mit einem motorischen Scanningtisch
US5878103A (en) 1997-06-30 1999-03-02 Siemens Corporate Research, Inc. Adaptive detector masking for speed-up of cone beam reconstruction
US5909476A (en) 1997-09-22 1999-06-01 University Of Iowa Research Foundation Iterative process for reconstructing cone-beam tomographic images
US6540895B1 (en) 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
US6388809B1 (en) 1997-10-29 2002-05-14 Digital Optical Imaging Corporation Methods and apparatus for improved depth resolution use of out-of-focus information in microscopy
US6037579A (en) 1997-11-13 2000-03-14 Biophotonics Information Laboratories, Ltd. Optical interferometer employing multiple detectors to detect spatially distorted wavefront in imaging of scattering media
CA2310672A1 (en) 1997-11-19 1999-05-27 University Of Washington High throughput optical scanner
US6251615B1 (en) 1998-02-20 2001-06-26 Cell Analytics, Inc. Cell analysis methods
US6291824B1 (en) 1998-04-13 2001-09-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Apparatus and method for high-bandwidth optical tomography
US6248988B1 (en) 1998-05-05 2001-06-19 Kla-Tencor Corporation Conventional and confocal multi-spot scanning optical microscope
US6529614B1 (en) 1998-08-05 2003-03-04 California Institute Of Technology Advanced miniature processing handware for ATR applications
CA2340097C (en) 1998-08-14 2011-10-25 Global Technovations, Inc. On-site analyzer
JP2000121550A (ja) 1998-10-16 2000-04-28 Japan Science & Technology Corp ヘテロダイン検波による生体試料の画像検出方法及びその装置
US6640014B1 (en) 1999-01-22 2003-10-28 Jeffrey H. Price Automatic on-the-fly focusing for continuous image acquisition in high-resolution microscopy
US7450229B2 (en) 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US8005314B2 (en) 2005-12-09 2011-08-23 Amnis Corporation Extended depth of field imaging for high speed object analysis
US6249341B1 (en) 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6608682B2 (en) 1999-01-25 2003-08-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6975400B2 (en) 1999-01-25 2005-12-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
DE19931954A1 (de) 1999-07-10 2001-01-11 Leica Microsystems Beleuchtungseinrichtung für ein DUV-Mikroskop
WO2001011341A2 (en) 1999-08-05 2001-02-15 Cellomics, Inc. A system for cell-based screening
US6239871B1 (en) 1999-08-24 2001-05-29 Waters Investments Limited Laser induced fluorescence capillary interface
US7003143B1 (en) 1999-11-02 2006-02-21 Hewitt Charles W Tomographic microscope for high resolution imaging and method of analyzing specimens
US6775399B1 (en) 1999-11-17 2004-08-10 Analogic Corporation ROI segmentation image processing system
US6365367B1 (en) 1999-12-06 2002-04-02 Cellomics, Inc. Environmental chamber for the analysis of live cells
US6549308B1 (en) 2000-01-11 2003-04-15 Zebra Imaging, Inc. Unibiased light field models for rendering and holography
JP4994560B2 (ja) 2000-08-25 2012-08-08 アムニス コーポレイション 細胞などの小さな移動物体の速度測定
WO2002018537A2 (en) 2000-08-29 2002-03-07 Yeda Research And Development Co. Ltd. Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
WO2002035474A1 (en) 2000-10-27 2002-05-02 Praelux Incorporated Method and apparatus for screening chemical compounds
WO2002049080A2 (en) 2000-12-15 2002-06-20 Kla Tencor Corporation Method and apparatus for inspecting a substrate
US6944322B2 (en) 2001-03-28 2005-09-13 Visiongate, Inc. Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
US6591003B2 (en) 2001-03-28 2003-07-08 Visiongate, Inc. Optical tomography of small moving objects using time delay and integration imaging
US6522775B2 (en) * 2001-03-28 2003-02-18 Alan C. Nelson Apparatus and method for imaging small objects in a flow stream using optical tomography
US20060023219A1 (en) 2001-03-28 2006-02-02 Meyer Michael G Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
US6519355B2 (en) 2001-03-28 2003-02-11 Alan C. Nelson Optical projection imaging system and method for automatically detecting cells having nuclear and cytoplasmic densitometric features associated with disease
GB0112392D0 (en) 2001-05-22 2001-07-11 Medical Res Council Optical imaging appartus and associated specimen support means
WO2003003057A2 (en) 2001-06-27 2003-01-09 Bioview Ltd. System and method for capturing multi-color fish images
US6741730B2 (en) 2001-08-10 2004-05-25 Visiongate, Inc. Method and apparatus for three-dimensional imaging in the fourier domain
US6636623B2 (en) * 2001-08-10 2003-10-21 Visiongate, Inc. Optical projection imaging system and method for automatically detecting cells with molecular marker compartmentalization associated with malignancy and disease
US6842297B2 (en) 2001-08-31 2005-01-11 Cdm Optics, Inc. Wavefront coding optics
US6850587B1 (en) 2001-10-24 2005-02-01 Analogic Corporation Reprojection-based three-dimensional image reconstruction
US7283253B2 (en) 2002-03-13 2007-10-16 Applied Precision, Llc Multi-axis integration system and method
US7197355B2 (en) * 2002-04-19 2007-03-27 Visiongate, Inc. Variable-motion optical tomography of small objects
US7260253B2 (en) 2002-04-19 2007-08-21 Visiongate, Inc. Method for correction of relative object-detector motion between successive views
US7738945B2 (en) 2002-04-19 2010-06-15 University Of Washington Method and apparatus for pseudo-projection formation for optical tomography
US20050085708A1 (en) 2002-04-19 2005-04-21 University Of Washington System and method for preparation of cells for 3D image acquisition
US7811825B2 (en) 2002-04-19 2010-10-12 University Of Washington System and method for processing specimens and images for optical tomography
US6697508B2 (en) 2002-05-10 2004-02-24 Visiongate, Inc. Tomographic reconstruction of small objects using a priori knowledge
US6770893B2 (en) 2002-05-13 2004-08-03 Visiongate, Inc. Method and apparatus for emission computed tomography using temporal signatures
US20040008515A1 (en) 2002-06-11 2004-01-15 Applied Precision Fluorescence illumination optimization for three-dimensional microscopy
US7274809B2 (en) 2002-08-29 2007-09-25 Perceptronix Medical, Inc. And British Columbia Cancer Agency Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
ES2257705T3 (es) 2002-08-30 2006-08-01 Medical Research Council Tomografia por proyeccion optica.
EP1602065A4 (en) 2003-02-18 2009-01-07 Oklahoma Med Res Found EXPANSION DEPTH OF MICROSCOPY OF FOCUS
US7260251B2 (en) * 2003-03-31 2007-08-21 Cdm Optics, Inc. Systems and methods for minimizing aberrating effects in imaging systems
US20040197839A1 (en) 2003-04-04 2004-10-07 Bioview Ltd. Methods of detecting cancer cells in biological samples
US7408176B2 (en) 2003-06-19 2008-08-05 Applied Precision, Llc System and method employing photokinetic techniques in cell biology imaging applications
JP2005018236A (ja) * 2003-06-24 2005-01-20 Denso Wave Inc Ｒｆタグ読取機器
JP2005331394A (ja) * 2004-05-20 2005-12-02 Olympus Corp 画像処理装置
JP4556111B2 (ja) * 2004-09-02 2010-10-06 ソニー株式会社 情報処理装置
US20070258122A1 (en) 2004-10-06 2007-11-08 Bc Cancer Agency Computer-Tomography Microscope and Computer-Tomography Image Reconstruction Methods
US6991738B1 (en) 2004-10-13 2006-01-31 University Of Washington Flow-through drum centrifuge
US20060096358A1 (en) 2004-10-28 2006-05-11 University Of Washington Optical projection tomography microscope
US7494809B2 (en) 2004-11-09 2009-02-24 Visiongate, Inc. Automated cell sample enrichment preparation method
US20060099707A1 (en) 2004-11-09 2006-05-11 Nelson Alan C Automated cell preparation system and method
WO2006076671A2 (en) 2005-01-13 2006-07-20 Whitehead Institute For Biomedical Research Method and apparatus for uv imaging
US7224540B2 (en) 2005-01-31 2007-05-29 Datalogic Scanning, Inc. Extended depth of field imaging system using chromatic aberration
JP2007147952A (ja) * 2005-11-28 2007-06-14 Konica Minolta Opto Inc 撮像光学系位置調整方法
JP2007151631A (ja) * 2005-11-30 2007-06-21 Kyocera Corp 光断層イメージング装置
JPWO2007083755A1 (ja) * 2006-01-20 2009-06-11 住友電気工業株式会社 分析装置、真贋判定装置、真贋判定方法、及び地中探索方法
US7569789B2 (en) 2006-03-16 2009-08-04 Visiongate, Inc. Cantilevered coaxial flow injector apparatus and method for sorting particles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485413B1 (en) * 1991-04-29 2002-11-26 The General Hospital Corporation Methods and apparatus for forward-directed optical scanning instruments
US6725073B1 (en) * 1999-08-17 2004-04-20 Board Of Regents, The University Of Texas System Methods for noninvasive analyte sensing
CN1383785A (zh) * 2002-06-14 2002-12-11 清华大学 一种带有自适应光程调节装置的光学相干层析成像系统
CN1875242A (zh) * 2003-10-27 2006-12-06 通用医疗公司 用于使用频域干涉测量法进行光学成像的方法和设备

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