CN101874861B - Medicament for treating and preventing heart diseases - Google Patents
Medicament for treating and preventing heart diseases Download PDFInfo
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- CN101874861B CN101874861B CN 200910250215 CN200910250215A CN101874861B CN 101874861 B CN101874861 B CN 101874861B CN 200910250215 CN200910250215 CN 200910250215 CN 200910250215 A CN200910250215 A CN 200910250215A CN 101874861 B CN101874861 B CN 101874861B
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Abstract
The invention discloses a medicament for treating and preventing heart diseases, a preparation method and an application method thereof. The medicament is prepared from the following raw materials by weight: 5 to 25 grams of Chinese angelica, 5 to 25 grams of saffron, 5 to 25 grams of rehmanniae praeparatum, 5 to 25 grams of chaff flower root, 10 to 30 grams of peach seed, 2 to 15 grams of szechuan lovage rhizome, 2 to 15 grams of platycodon root, 5 to 20 grams of red paeony root, 5 to 20 grams of fructus citri immaturus exsiccatus, 1 to 10 grams of Chinese thorowax root and 1 to 10 grams of liquorice root serving as ingredients A and 25 to 70 grams of root of red-rooted salvia, 20 to 50 grams of white paeony root, 60 to 100 grams of swordlike atractylodes rhizome, 20 to 50 grams of cortex magnoliae officinalis, 15 to 45 grams of cassia bark, 10 to 30 grams of cooked prepared common monkshood caughter root, 5 to 15 grams of liquorice root, 15 to 40 grams of szechuan lovage rhizome, 20 to 50 grams of peach seed and 10 to 30 grams of saffron serving as ingredients B. The medicament has the effects of tonifying blood and nourishing heart, nourishing qi and soothing the nerves, nourishing yin and falling fire, nourishing the heart and soothing the nerves, warming and invigorating heart-wang, soothing the nerves and relieving palpitation, inspiring heart-yang, activating function of qi for promoting diuresis, promoting blood circulation by removing blood stasis and regulating vital energy and removing obstruction in channels.
Description
Technical field
The present invention relates to medicine and preparation method thereof and the using method of a kind for the treatment of and prevention of cardiac, more particularly, relate to a kind of the treatment take Chinese medicine as raw material and the medicine of prevention of cardiac and preparation method thereof and using method.
Background technology
Cause the factor of outbreak of cardiovascular disease a lot, its pathogeny is also complicated, so, be called one of human main causes of death by modern medicine, and the cardiopathic medicine of research treatment is also a lot, such as nitroglycerin, be characterized in instant effect, remission to acute patient is evident in efficacy, but has certain side effect, also has some Chinese patent medicines, such as SUXIAO JIUXIN WAN, storax pill for treating coronary heart disease etc., also have instant effect, effective characteristics, but a kind of medicine only works for one type heart disease, is not suitable for the cardiac of other type.
Summary of the invention
One of purpose of the present invention provides medicine of a kind for the treatment of and prevention of cardiac and preparation method thereof and using method.
Two of purpose of the present invention is only to work for one type heart disease in order to solve existing a kind of Chinese patent medicine, be not suitable for the cardiopathic problem of other type, and a kind of overcome above-mentioned shortcoming, the suitable cardiopathic medicine of the cardiopathic treatment of polytype are provided.
This and other purpose of the present invention will be further reflected and elaborated by the following detailed description and explanation.
Solution of the present invention is based on motherland's medical science to the pathogenetic understanding of heart disease and Therapeutic Principle, achieve with reference to modern pharmacological research, in conjunction with modern about research data and long-term clinical practice, think and have inseparable relation between kidney and the heart, suffer from a deficiency of the kidney, blood stasis is the main mechanism of heart morbidity, invigorating kidney, promoting blood circulation is the cardiopathic effective way for the treatment of, the present invention is from motherland's medicine treasure-house, filter out blood circulation promoting and blood stasis dispelling, heart tonifying power, QI invigorating is empty, pure and impure remittance, the body resistance strengthening and constitution consolidating, the Chinese herbal medicine of medicated diet homology, with invigorating kidney, promoting blood circulation refinforce each other reach the treatment cardiopathic purpose.
The medicine for the treatment of of the present invention and prevention of cardiac is the medicine of being made by the raw material of following weight portion:
The A composition:
Radix Angelicae Sinensis 5-25 Stigma Croci 5-25 Radix Rehmanniae 5-25
Radix Achyranthis Bidentatae 5-25 Semen Persicae 10-30 Rhizoma Chuanxiong 2-15
Radix Platycodonis 2-15 Radix Paeoniae Rubra 5-20 Fructus Aurantii 5-20
Radix Bupleuri 1-10 Radix Glycyrrhizae 1-10
The B composition:
Radix Salviae Miltiorrhizae 25-70 Radix Paeoniae Alba 20-50 Rhizoma Atractylodis 60-100
Cortex Magnoliae Officinalis 20-50 Cortex Cinnamomi 15-45 Radix Aconiti Lateralis Preparata 10-30
Radix Glycyrrhizae 5-15 Rhizoma Chuanxiong 15-40 Semen Persicae 20-50
Stigma Croci 10-30.
Further, the medicine for the treatment of of the present invention and prevention of cardiac is the medicine of being made by the raw material of following weight portion:
The A composition:
Radix Angelicae Sinensis 10-20 Stigma Croci 10-20 Radix Rehmanniae 10-20
Radix Achyranthis Bidentatae 10-20 Semen Persicae 15-25 Rhizoma Chuanxiong 5-10
Radix Platycodonis 5-10 Radix Paeoniae Rubra 5-15 Fructus Aurantii 5-15
Radix Bupleuri 3-8 Radix Glycyrrhizae 3-8
The B composition:
Radix Salviae Miltiorrhizae 35-60 Radix Paeoniae Alba 30-50 Rhizoma Atractylodis 70-90
Cortex Magnoliae Officinalis 30-50 Cortex Cinnamomi 25-40 Radix Aconiti Lateralis Preparata 15-25
Radix Glycyrrhizae 8-15 Rhizoma Chuanxiong 20-30 Semen Persicae 30-50
Stigma Croci 15-25.
Be preferably, the medicine for the treatment of of the present invention and prevention of cardiac is the medicine of being made by the raw material of following weight portion:
The A composition:
Radix Angelicae Sinensis 15 Stigma Crocis 15 Radix Rehmanniae 15
Radix Achyranthis Bidentatae 15 Semen Persicaes 20 Rhizoma Chuanxiongs 8
Radix Platycodonis 8 Radix Paeoniae Rubra 10 Fructus Aurantiis 10
Radix Bupleuri 5 Radix Glycyrrhizaes 5
The B composition:
Radix Salviae Miltiorrhizae 50 Radix Paeoniae Albas 40 Rhizoma Atractylodis 80
Cortex Magnoliae Officinalis 40 Cortex Cinnamomis 30 Radix Aconiti Lateralis Preparata 20
Radix Glycyrrhizae 10 Rhizoma Chuanxiongs 25 Semen Persicaes 40
Stigma Croci 20.
The process for preparing medicine for the treatment of of the present invention and prevention of cardiac is that said medicine is cleaned, and A composition raw material is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, and the water cooking liquid of merging secondary obtains A composition medicinal liquid; Fine powder is cleaned, worn into to B composition raw material be mixed to get B composition medicine.
Be preferably, the process for preparing medicine for the treatment of of the present invention and prevention of cardiac is that said medicine is cleaned, and A composition raw material is added doubly decocting in water 1-2 hour of 2-3, repeats 2 times, and the water cooking liquid of merging secondary obtains A composition medicinal liquid; Fine powder is cleaned, worn into to B composition raw material be mixed to get B composition medicine.
The using method for the treatment of of the present invention and prevention of cardiac medicine is A composition medicinal liquid to be divided into five pairs of medicines eat one pair every day, divides and eats for three times, B composition medicine is taken after mixing it with water one time seven to ten gram, one day twice with warm water.
Medicine of the present invention has replenishing blood for nourishing heart, foster the spirit of nobility and calm the nerves, nourishing YIN to lower pathogenic fire, tranquilizing by nourishing the heart, warmly invigorating heart-YANG, calm the nerves and surely throb with fear, rouse oneself the effect of heart-yang, promote the circulation of qi and water, invigorating blood circulation what, regulating qi and dredging collateral.
The present invention compared with prior art and has the following advantages and good effect through clinical trial proof:
1, Chinese medicine of the present invention is comprehensively reconciled indication, and treating both the principal and secondary aspects of a disease reaches the healing rehabilitation, eliminates the how upper symptom in the past controlled respectively a kind of disease with multiple medicine, cure the symptoms, not the disease and side effect large, often cause new drug-induced disease and the drawback of complication;
2, indication instant effect, short treating period, effective percentage are reached 98%, cure and do not recur, follow up a case by regular visits to no recurrence in 2 years to curing patient's tracking;
3, nontoxic to human body, long-term taking is impairing the liver kidney no dependence not, and prevention of cardiac and body building health-care effect are arranged;
4, alleviate patient's financial burden, eliminate patient's Psychological phobia and mental suffering, improve the quality of living.
By the following specific examples further illustrate the invention, but embodiment only is used for explanation, can not limit the scope of the invention.
In the present invention, if not refer in particular to, all parts, amount, percentage ratio are unit of weight, and all raw materials all can be buied from market.
The specific embodiment
Embodiment 1
Take by weighing raw material by following proportioning:
The A composition:
Radix Angelicae Sinensis 15 grams, Stigma Croci 15 grams, the Radix Rehmanniae 15 grams, Radix Achyranthis Bidentatae 15 grams, Semen Persicae 20 grams, Rhizoma Chuanxiong 8 grams, Radix Platycodonis 8 grams, Radix Paeoniae Rubra 10 grams, Fructus Aurantii 10 grams, Radix Bupleuri 5 grams, Radix Glycyrrhizae 5 grams.
The B composition:
Radix Salviae Miltiorrhizae 50 grams, the Radix Paeoniae Alba 40 grams, Rhizoma Atractylodis 80 grams, Cortex Magnoliae Officinalis 40 grams, Cortex Cinnamomi 30 grams, Radix Aconiti Lateralis Preparata 20 grams, Radix Glycyrrhizae 10 grams, Rhizoma Chuanxiong 25 grams, Semen Persicae 40 grams, Stigma Croci 20 grams.
The process for preparing medicine for the treatment of of the present invention and prevention of cardiac is that said medicine is cleaned, and A composition raw material is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, and the water cooking liquid of merging secondary obtains A composition medicinal liquid; Fine powder is cleaned, worn into to B composition raw material be mixed to get B composition medicine.
The using method for the treatment of of the present invention and prevention of cardiac medicine is A composition medicinal liquid to be divided into five pairs of medicines eat one pair every day, divides and eats for three times, B composition medicine is taken after mixing it with water one time seven to ten gram, one day twice with warm water.
Embodiment 2
Take by weighing raw material by following proportioning:
The A composition:
Radix Angelicae Sinensis 18 grams, Stigma Croci 18 grams, the Radix Rehmanniae 18 grams, Radix Achyranthis Bidentatae 18 grams, Semen Persicae 24 grams, Rhizoma Chuanxiong 10 grams, Radix Platycodonis 10 grams, Radix Paeoniae Rubra 8 grams, Fructus Aurantii 8 grams, Radix Bupleuri 4 grams, Radix Glycyrrhizae 4 grams.
The B composition:
Radix Salviae Miltiorrhizae 60 grams, the Radix Paeoniae Alba 45 grams, Rhizoma Atractylodis 80 grams, Cortex Magnoliae Officinalis 45 grams, Cortex Cinnamomi 35 grams, Radix Aconiti Lateralis Preparata 22 grams, Radix Glycyrrhizae 13 grams, Rhizoma Chuanxiong 27 grams, Semen Persicae 45 grams, Stigma Croci 25 grams.
The process for preparing medicine for the treatment of of the present invention and prevention of cardiac is that said medicine is cleaned, and A composition raw material is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, and the water cooking liquid of merging secondary obtains A composition medicinal liquid; Fine powder is cleaned, worn into to B composition raw material be mixed to get B composition medicine.
The using method for the treatment of of the present invention and prevention of cardiac medicine is A composition medicinal liquid to be divided into five pairs of medicines eat one pair every day, divides and eats for three times, B composition medicine is taken after mixing it with water one time seven to ten gram, one day twice with warm water.
Embodiment 3
Take by weighing raw material by following proportioning:
The A composition:
Radix Angelicae Sinensis 16 grams, Stigma Croci 18 grams, the Radix Rehmanniae 13 grams, Radix Achyranthis Bidentatae 12 grams, Semen Persicae 28 grams, Rhizoma Chuanxiong 10 grams, Radix Platycodonis 10 grams, Radix Paeoniae Rubra 12 grams, Fructus Aurantii 12 grams, Radix Bupleuri 6 grams, Radix Glycyrrhizae 5 grams.
The B composition:
Radix Salviae Miltiorrhizae 45 grams, the Radix Paeoniae Alba 42 grams, Rhizoma Atractylodis 88 grams, Cortex Magnoliae Officinalis 43 grams, Cortex Cinnamomi 36 grams, Radix Aconiti Lateralis Preparata 18 grams, Radix Glycyrrhizae 11 grams, Rhizoma Chuanxiong 28 grams, Semen Persicae 50 grams, Stigma Croci 16 grams.
The process for preparing medicine for the treatment of of the present invention and prevention of cardiac is that said medicine is cleaned, and A composition raw material is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, and the water cooking liquid of merging secondary obtains A composition medicinal liquid; Fine powder is cleaned, worn into to B composition raw material be mixed to get B composition medicine.
The using method for the treatment of of the present invention and prevention of cardiac medicine is A composition medicinal liquid to be divided into five pairs of medicines eat one pair every day, divides and eats for three times, B composition medicine is taken after mixing it with water one time seven to ten gram, one day twice with warm water.
Embodiment 4: clinical
1, Lv Guifang, the woman 68 years old, lives the Jiaohe City, Jilin Province.Suffering from a heart complaint, it is bad to cure for many years.Introduced through others in 2002 and take this medicine, reporting the attitude of trying, taken five pairs of medicines after, it is pretty good that heart is felt, taken again five pairs of medicines, heart disease is violated so far.
2, Zhang Wen, the man 60 years old, lives Jilin Province's Yanji.Just have a heart disease during one's thirties, older after, more serious, what taskwork is not all done.Took this medicine in 2004, four pairs all right, and now what work can both have been done.
3, gold becomes, the man, and 52 years old, live the Yanji .2000 of Jilin Province and go to Korea S to do manual work, suffer from heart disease, behind the obstinate, it is all right to take seven pairs of this medicines.
4, willow, woman, 22 years old, Jilin Province's public relation student of institute.Suffer from congenital heart disease from little, the time and show effect, took this medicine in 1998 not recommit till now, it is fully good to have taken ten pairs of medicines.
5, Hao Yue, the woman, 16 years old, Changchun City honked the experimental school student.Have a heart disease, took medicine one month summer vacation calendar year 2001, so far the criminal of not having.
6, Qiao Xue, the woman, 17 years old, the chief personnel's of Changling county of Jilin province grains bureau daughter had a heart disease, and many places are cured bad, take this medicine ten and pay to the modern criminal of not having.
7, Hu Daocheng, the man 70 years old, lives the Tongliao City, Jilin Province.Have a heart disease during three teens, it is as excellent as before to take ten pairs of hearts of this medicine in 85 years.
8, Song Wenyuan, the man 65 years old, lives the inthe Shanmen area, Siping, Jilin province city.Suffer from heart disease for many years, have an injection to take medicine and do not feel any better, take seven pairs of heart disease recoveries from illness of this medicine.
9, Song Tiancheng, the man 46 years old, lives Benxi, Liaoning Province.Have a heart disease, many places are cured and not to be felt any better, and rear to take five pairs of this medicines all right.
10, Hao Li comes, and the man 42 years old, lives near No. 2 bridges in Dandong City, Liaoning Province.Checked and find to have a heart disease that it is just normal to take ten pairs of this medicines in 1988.
11, Meng Xiang, man, 52 years old, the Red Star farm hand of Heilongjiang Province.Having a heart disease, seeks medical advice and medicine in many places, also has no improvement, and rear 12 pairs of this medicines that take just do not commit excesses so far.
12, Jiang Liankui, man, 60 years old, Huhehaote rail man.Had a heart disease in 2005, it is all right to take 8 pairs of this medicines, so far the criminal of not having.
13, Yan Jie, the woman 40 years old, lives the Changchun City Lvyuan District.Have a heart disease, it is all right to take five pairs of this medicines.
14, Jiang Xiaotian, the man 58 years old, lives near the Qing Jiangxian of Zhejiang Province the second Machinery Plant of Light Industry.Suffered from a heart complaint in 96 years, and took 10 pairs of recoveries from illness of this medicine.
15, Wu Youcai, the man 58 years old, lives the Jixi, Heilongjiang city.Have a heart disease in one's early years, cure and do not take effect, rear ten pairs of this medicines that take, heart has just recovered, and does not violate so far.
Embodiment 5:
One, clinical data:
The case history that clinical verification is selected all meets the requirements of defined in the checking design, and take the case history of being in hospital as main, patient medical history is auxiliary, observes 150 examples, test group 100 examples wherein, and matched group 50 examples, each is organized sex, age and sees Table 1.Disease symptoms sees Table 2.
Each test group sex of table 1, age
Table 2 disease symptoms
Two, dosage and method:
Test group: medicine of the present invention, A composition medicinal liquid is divided into five pairs of medicines eats one pair every day, divide and eat for three times, B composition medicine is taken after mixing it with water one time seven to ten gram, one day twice with warm water.
Matched group: Radix Notoginseng is taken after mixing it with water, every day 3 times, and each 2 grams, the empty stomach warm boiled water, one month is a course for the treatment of.In test, cut out the medicine of other treatment coronary heart disease and angina pectoris class.
Three, criterion of therapeutical effect and judgement:
Recovery from illness: coronary heart disease and angina pectoris symptom complete obiteration.
Produce effects: coronary heart disease and angina pectoris symptom, the most of disappearance.
Invalid: coronary heart disease and angina pectoris symptom improve not obvious.
Therapeutic outcome is judged:
Efficient statistics and significance compare: the comparison sheet X of test group and matched group Different therapeutical effect
2The statistical processing methods of test:
The efficient statistics of table 3
Through X
2Check, the total effective rate of test group reaches 98%, and the matched group total effective rate is 66%, and test group and matched group Different therapeutical effect are remarkable.
Table 4 effectively compares the course for the treatment of
The effectively comparative analysis course for the treatment of: the test group treatment shortest time is 30-90 days, and what reach effective standard is 98%.
Matched group: treatment time reached more than 90 days, and what reach effective standard accounts for 66%, test group and matched group significant difference.
From this group clinical statistics, the total effective rate of medicine of the present invention, observing time the internal therapy rate be 98%.And the effective percentage of matched group medicine within observing time is 66%.
Statistical analysis is processed: both effective percentage have significant difference, and the effect of the treatment of test group is fast, and short treating period is better than the matched group medicine.
Claims (3)
1. the medicine of a treatment and prevention of cardiac is characterized in that it is the medicine of being made by the crude drug of following weight portion:
The A composition:
Radix Angelicae Sinensis 5-25 Stigma Croci 5-25 Radix Rehmanniae 5-25
Radix Achyranthis Bidentatae 5-25 Semen Persicae 10-30 Rhizoma Chuanxiong 2-15
Radix Platycodonis 2-15 Radix Paeoniae Rubra 5-20 Fructus Aurantii 5-20
Radix Bupleuri 1-10 Radix Glycyrrhizae 1-10
Wherein the A composition prepares as follows: the above-mentioned raw materials medicine is cleaned, A composition crude drug is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, the water cooking liquid of merging secondary obtains A composition medicinal liquid;
The B composition:
Radix Salviae Miltiorrhizae 25-70 Radix Paeoniae Alba 20-50 Rhizoma Atractylodis 60-100
Cortex Magnoliae Officinalis 20-50 Cortex Cinnamomi 15-45 Radix Aconiti Lateralis Preparata 10-30
Radix Glycyrrhizae 5-15 Rhizoma Chuanxiong 15-40 Semen Persicae 20-50
Stigma Croci 10-30
Wherein the B composition prepares as follows: fine powder is cleaned, worn into to B composition crude drug be mixed to get B composition medicine.
2. the medicine for the treatment of according to claim 1 and prevention of cardiac is characterized in that it is the medicine of being made by the crude drug of following weight portion:
The A composition:
Radix Angelicae Sinensis 10-20 Stigma Croci 10-20 Radix Rehmanniae 10-20
Radix Achyranthis Bidentatae 10-20 Semen Persicae 15-25 Rhizoma Chuanxiong 5-10
Radix Platycodonis 5-10 Radix Paeoniae Rubra 5-15 Fructus Aurantii 5-15
Radix Bupleuri 3-8 Radix Glycyrrhizae 3-8
Wherein the A composition prepares as follows: the above-mentioned raw materials medicine is cleaned, A composition crude drug is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, the water cooking liquid of merging secondary obtains A composition medicinal liquid;
The B composition:
Radix Salviae Miltiorrhizae 35-60 Radix Paeoniae Alba 30-50 Rhizoma Atractylodis 70-90
Cortex Magnoliae Officinalis 30-50 Cortex Cinnamomi 25-40 Radix Aconiti Lateralis Preparata 15-25
Radix Glycyrrhizae 8-15 Rhizoma Chuanxiong 20-30 Semen Persicae 30-50
Stigma Croci 15-25
Wherein the B composition prepares as follows: fine powder is cleaned, worn into to B composition crude drug be mixed to get B composition medicine.
3. the medicine for the treatment of according to claim 1 and prevention of cardiac is characterized in that it is the medicine of being made by the crude drug of following weight portion:
The A composition:
Radix Angelicae Sinensis 15 Stigma Crocis 15 Radix Rehmanniae 15
Radix Achyranthis Bidentatae 15 Semen Persicaes 20 Rhizoma Chuanxiongs 8
Radix Platycodonis 8 Radix Paeoniae Rubra 10 Fructus Aurantiis 10
Radix Bupleuri 5 Radix Glycyrrhizaes 5
Wherein the A composition prepares as follows: the above-mentioned raw materials medicine is cleaned, A composition crude drug is added doubly decocting in water 2-3 hour of 2-3, repeats 2 times, the water cooking liquid of merging secondary obtains A composition medicinal liquid;
The B composition:
Radix Salviae Miltiorrhizae 50 Radix Paeoniae Albas 40 Rhizoma Atractylodis 80
Cortex Magnoliae Officinalis 40 Cortex Cinnamomis 30 Radix Aconiti Lateralis Preparata 20
Radix Glycyrrhizae 10 Rhizoma Chuanxiongs 25 Semen Persicaes 40
Stigma Croci 20
Wherein the B composition prepares as follows: fine powder is cleaned, worn into to B composition crude drug be mixed to get B composition medicine.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1491706A (en) * | 2003-08-02 | 2004-04-28 | 浙江天一堂集团有限公司 | Soft capsule for removing blood stasis in chest and its preparing method |
CN1961928A (en) * | 2005-11-10 | 2007-05-16 | 杨文龙 | Blood circulation-activating stasis-removing medicament for treating blood stasis syndrome and preparation process thereof |
CN101537074A (en) * | 2008-03-21 | 2009-09-23 | 北京汉潮联创中药科技有限公司 | Chinese traditional medicine preparation for curing coronary heart disease with angina pectoris |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1491706A (en) * | 2003-08-02 | 2004-04-28 | 浙江天一堂集团有限公司 | Soft capsule for removing blood stasis in chest and its preparing method |
CN1961928A (en) * | 2005-11-10 | 2007-05-16 | 杨文龙 | Blood circulation-activating stasis-removing medicament for treating blood stasis syndrome and preparation process thereof |
CN101537074A (en) * | 2008-03-21 | 2009-09-23 | 北京汉潮联创中药科技有限公司 | Chinese traditional medicine preparation for curing coronary heart disease with angina pectoris |
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