CN103028062B - Traditional Chinese medicine for treating ankylosing spondylitis - Google Patents

Traditional Chinese medicine for treating ankylosing spondylitis Download PDF

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CN103028062B
CN103028062B CN201210587991.9A CN201210587991A CN103028062B CN 103028062 B CN103028062 B CN 103028062B CN 201210587991 A CN201210587991 A CN 201210587991A CN 103028062 B CN103028062 B CN 103028062B
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radix
chinese medicine
ankylosing spondylitis
traditional chinese
medicine
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CN201210587991.9A
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CN103028062A (en
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单文英
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Dan Wenying
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Abstract

The invention relates to traditional Chinese medicine for treating ankylosing spondylitis. The traditional Chinese medicine is prepared by 30-60g astragalus mongholicus, 10-20g rhizoma cibotii, 10-20g eucommia ulmoides, 6-10g dogwood, 10-15g fructus lycii, 10-20g loranthus parasiticus, 10-15g radix angelicae sinensis, 10-30g raw radix paeoniae alba, 10-15g radix clematidis, 20-50g honeysuckle stem, 30-60g hedyotis diffusa, 10-20g radix puerariae, 10-30g polygonum cuspidatum, 15-30g raw semen coicis, 10-15g medicinal cyathula root, 6-10g silkworm excrement, 6-10g liquorice, 2-3g cassia bark, 5-10g eupolyphaga, 6-15g lumbricus, and 10-20g zaocys dhumnade. The medicine is a pure traditional Chinese medicine preparation, and small in toxic and side effect, has a significant curative effect on the ankylosing spondylitis, and is suitable for clinical popularization and application.

Description

A kind of Chinese medicine for the treatment of ankylosing spondylitis
Technical field
The present invention relates to a kind of medicine for the treatment of ankylosing spondylitis, be specifically related to a kind of medicine of the treatment ankylosing spondylitis being prepared from by Chinese herbal medicine.
Background technology
Ankylosing spondylitis is a kind of rheumatic immune disease clinically, mainly invades sacroiliac joint, spinal column apophysis, the other soft tissue of spinal column and periphery joint etc., and more, disability rate is high, is to generally acknowledge refractory disease both at home and abroad for the touching difficulty of its course of disease.Existing treatment means adopts immunosuppressant and glucocorticoid etc. more, and patient's prolonged application is difficult to tolerance, and through clinical long-term observation, existing doctor trained in Western medicine technology and medicine can only mitigate the disease and can not cure, after drug withdrawal easily repeatedly or symptom before increase the weight of.Western medicine there is no desirable curative effect, and Chinese medicine is controlled ankylosing spondylitis more advantage, respond well, but lacks the medicine of this respect, can not meet the needs of clinical treatment.
Summary of the invention
In order to address the above problem, the invention provides a kind of Chinese medicine for the treatment of ankylosing spondylitis.
The present invention is achieved through the following technical solutions: a kind of Chinese medicine for the treatment of ankylosing spondylitis, medical material by following weight is prepared from: Radix Astragali 30-60g, Rhizoma Cibotii 10 ~ 20g, the Cortex Eucommiae 10 ~ 20g, Fructus Corni 6 ~ 10g, Fructus Lycii 10 ~ 15g, Herba Taxilli 10 ~ 20g, Radix Angelicae Sinensis 10 ~ 15g, Radix Paeoniae Alba 10 ~ 30g, Radix Clematidis 10 ~ 15g, Caulis Lonicerae 20 ~ 50g, Herba Hedyotidis Diffusae 30 ~ 60g, Radix Puerariae 10 ~ 20g, Rhizoma Polygoni Cuspidati 10 ~ 30g, Semen Coicis 15 ~ 30g, Radix Cyathulae 10 ~ 15g, Bombyx mori L. 6 ~ 10g, Radix Glycyrrhizae 6 ~ 10g, Cortex Cinnamomi 2 ~ 3g, , eupolyphaga 5-10g, Pheretima 6-15g, Zaocys 10-20g.
The present invention adopts and is prepared as follows method preparation: get above each taste, add the decocting of 8 times, 6 times amounts to boil twice, each two hours, merging filtrate, was concentrated into relative density and is 1.10-1.20, for subsequent use.
In we, Rhizoma Cibotii, the Cortex Eucommiae, Herba Taxilli, Fructus Corni, Fructus Lycii invigorating the liver and kidney enter governor vessel, bone and muscle strengthening, strong waist knee joint, wind-damp dispelling, diffusing impediment and relieving pain.Radix Angelicae Sinensis, Radix Astragali invigorating the spleen and benefiting QI, the essence of foster acquired essence nourishing congenital essence; Radix Puerariae, the Radix Paeoniae Alba, Radix Glycyrrhizae, the broken constipation of YIN type of Bombyx mori L., muscles and tendons relaxing to alleviate pain; Radix Clematidis leads to the twelve regular channels, expelling wind and removing dampness; More there is Rhizoma Polygoni Cuspidati, give birth to the quality goods of Semen Coicis repercussive by phlegm-damp.The turbid poison of Caulis Lonicerae, Herba Hedyotidis Diffusae solution meridians; Cortex Cinnamomi helps the fire of Yu's door, current QI and blood passages through which vital energy circulates, and the moon of Radix Achyranthis Bidentatae invigorating the liver and kidney, promoting blood circulation to remove obstruction in the collateral, two medicines share mends lower unit void, controls upward floating of YANG in deficiency condition; Mend Kidney-Yin void, press down the inflammation of asthenic fire, same to let the fire back to its origin.Eupolyphaga, Pheretima, Zaocys Drug Prepared from Insects blood circulation promoting and blood stasis dispelling, activate yang and walk to alter, and draws all medicines and enter Li Dabiao.Each medicine share plays expelling wind and removing dampness altogether, and nourishing the liver and kidney, promoting blood circulation to remove obstruction in the collateral reach the object for the treatment of ankylosing spondylitis jointly.
clinical data
Case source: get patient's 60 examples that are diagnosed as ankylosing spondylitis, be divided at random treatment group and matched group.Wherein matched group, male's 18 examples, women's 12 examples, course of disease 0.3-12, age 22-44 year; Treatment group male's 19 examples, women's 11 examples, course of disease 0.4-42 year, age 23-44 year, age, the sex no significant difference of each group.
Therapeutic Method: matched group gives oral salazosulfadimidine, by specification amount is taken.
Treatment group gives the medicine that the embodiment of the present invention 1 is prepared from, and a prescription is a consumption per day, and point morning, noon and afternoon take for three times.Within one month, be a course for the treatment of, further consultation after 2 courses for the treatment of.
Criterion of therapeutical effect:
With reference to " new Chinese medicine guideline of clinical investigations " standard formulation.Effective: remission is obvious, joint and spinal function range of activity increase, and it is normal that erythrocyte sedimentation rate recovers, and x-ray shows that bone lesion is improved or without development, recovers normal work and work.Effective: symptom alleviates substantially, joint and spinal function range of activity have increased slightly, and can't take care of oneself and transfer self-care to, and erythrocyte sedimentation rate reduces.Invalid: treat 2 more than the course for the treatment of, relatively front with treatment, each side is all without progressive.
Therapeutic outcome:
Therapeutic outcome is added up as following table
Group Number of cases Effective Effectively Invalid Effective percentage (%)
Treatment group 30 17 11 2 93.33
Matched group 30 9 10 9 63.33
As fully visible, the effective percentage of Drug therapy of the present invention, much larger than the effective percentage of matched group, illustrates that medicine of the present invention has significant curative effect.
The present invention is pure Chinese medicinal preparation, and toxic and side effects is little, evident in efficacy, and clinic is applied.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further.
Embodiment 1
Get Radix Astragali 45g, Rhizoma Cibotii 15g, Cortex Eucommiae 15g, Fructus Corni 8g, Fructus Lycii 13g, Herba Taxilli 15g, Radix Angelicae Sinensis 13g, Radix Paeoniae Alba 20g, Radix Clematidis 13g, Caulis Lonicerae 35g, Herba Hedyotidis Diffusae 45g, Radix Puerariae 15g, Rhizoma Polygoni Cuspidati 20g, Semen Coicis 25g, Radix Cyathulae 12g, Bombyx mori L. 8g, Radix Glycyrrhizae 8g, Cortex Cinnamomi 2.5g,, eupolyphaga 8g, Pheretima 10g, Zaocys 15g.Add 8 times, the decocting of 6 times of amounts boils twice, and each two hours, merging filtrate, was concentrated into relative density and is 1.10-1.20, for subsequent use.
Embodiment 2
Get Radix Astragali 30g, Rhizoma Cibotii 10g, Cortex Eucommiae 10g, Fructus Corni 6g, Fructus Lycii 10g, Herba Taxilli 10g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 10g, Radix Clematidis 10g, Caulis Lonicerae 20g, Herba Hedyotidis Diffusae 30g, Radix Puerariae 10g, Rhizoma Polygoni Cuspidati 10g, Semen Coicis 15g, Radix Cyathulae 10g, Bombyx mori L. 6g, Radix Glycyrrhizae 6g, Cortex Cinnamomi 2g,, eupolyphaga 5g, Pheretima 6g, Zaocys 10g, add 8 times, the decocting of 6 times of amounts boils twice, each two hours, merging filtrate, be concentrated into relative density and be 1.10-1.20, for subsequent use.
Embodiment 3
Get Radix Astragali 60g, Rhizoma Cibotii 20g, Cortex Eucommiae 20g, Fructus Corni 10g, Fructus Lycii 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 30g, Radix Clematidis 15g, Caulis Lonicerae 50g, Herba Hedyotidis Diffusae 60g, Radix Puerariae 20g, Rhizoma Polygoni Cuspidati 30g, Semen Coicis 30g, Radix Cyathulae 15g, Bombyx mori L. 10g, Radix Glycyrrhizae 10g, Cortex Cinnamomi 3g,, eupolyphaga 10g, Pheretima 15g, Zaocys 20g; Add the decocting of 8 times, 6 times amounts to boil twice, each two hours, merging filtrate, was concentrated into relative density and is 1.10-1.20, for subsequent use.

Claims (1)

1. treat a Chinese medicine composition for ankylosing spondylitis, be prepared from by the medical material of following weight: Radix Astragali 30-60g, Rhizoma Cibotii 10 ~ 20g, the Cortex Eucommiae 10 ~ 20g, Fructus Corni 6 ~ 10g, Fructus Lycii 10 ~ 15g, Herba Taxilli 10 ~ 20g, Radix Angelicae Sinensis 10 ~ 15g, Radix Paeoniae Alba 10 ~ 30g, Radix Clematidis 10 ~ 15g, Caulis Lonicerae 20 ~ 50g, Herba Hedyotidis Diffusae 30 ~ 60g, Radix Puerariae 10 ~ 20g, Rhizoma Polygoni Cuspidati 10 ~ 30g, Semen Coicis 15 ~ 30g, Radix Cyathulae 10 ~ 15g, Bombyx mori L. 6 ~ 10g, Radix Glycyrrhizae 6 ~ 10g, Cortex Cinnamomi 2 ~ 3g, eupolyphaga 5 ~ 10g, Pheretima 6 ~ 15g, Zaocys 10 ~ 20g.
CN201210587991.9A 2012-12-31 2012-12-31 Traditional Chinese medicine for treating ankylosing spondylitis Expired - Fee Related CN103028062B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101632737A (en) * 2008-07-23 2010-01-27 吉林一正药业集团有限公司 Medicament for relieving pain of human body and preparation method thereof
CN101987123A (en) * 2009-08-05 2011-03-23 吉林一正药业集团有限公司 Medicament for easing pain of human body and preparation method thereof
CN101987122A (en) * 2009-08-05 2011-03-23 吉林一正药业集团有限公司 Medicament for easing pain of human body and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101632737A (en) * 2008-07-23 2010-01-27 吉林一正药业集团有限公司 Medicament for relieving pain of human body and preparation method thereof
CN101987123A (en) * 2009-08-05 2011-03-23 吉林一正药业集团有限公司 Medicament for easing pain of human body and preparation method thereof
CN101987122A (en) * 2009-08-05 2011-03-23 吉林一正药业集团有限公司 Medicament for easing pain of human body and preparation method thereof

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