CN101953908A - Chinese medicinal composition for treating pain in waist and lower extremities and preparation method thereof - Google Patents
Chinese medicinal composition for treating pain in waist and lower extremities and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating pain in waist and lower extremities and a preparation method thereof. The Chinese medicinal composition comprises the following raw materials: dipsacus root, east asian tree fern rhizome, mulberry twig, suberect spatholobus stem, ground beeltle, earthworm, centipede, prepared common monkshood mother root, prepared kusnezoff monkshood root, white mustard seed, folium epimedii, herba pyrolae, and sward. The preparation method comprises the following steps of: weighting raw materials according to a formula, and decocting the raw materials in water twice, namely, in the first decoction process, adding the water in an amount which is 2 times the total amount of the raw materials, immersing the raw materials for 10 to 30 minutes, decocting the raw materials for 30 to 40 minutes, and filtering out the decoction, and in the second decoction process, adding the water in an amount which is 1 time the total amount of the raw materials, decocting the raw materials for 15 to 20 minutes, and filtering out decoction; and mixing the decoction of the primary decoction with that of the secondary decoction to obtain the Chinese medicinal composition. The Chinese medicinal composition serving as a pure Chinese medicinal preparation has the advantages of low cost, no toxic or side effect, convenient preparation and administration, suitability for popularization and use, reasonable formula structures of prescriptions and rigorous compatibility; and the clinical application practice proves that the Chinese medicinal composition has the obvious curative effect, is particularly suitable for treating pain in waist and lower extremities of middle and old-aged people and can quicken the remission of postoperative symptoms and reduce the occurrence of operation complications.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of Chinese medicine composition for the treatment of lumbago and skelalgia and preparation method thereof.
Background technology
Lumbago and skelalgia is the very common disease of middle-aged and elderly people, is common in diseases such as the described lumbar degenerative spondylitis of modern medicine, prolapse of lumbar intervertebral disc, lumbar spinal stenosis, lumbar spondylolisthesis, myofascitis of back, lumbar muscle strain, piriformis syndrome, superior giuteus nerve neuritis.It causes the walking and the obstacle of movable function, influences middle-aged and elderly people quality of life.Motherland's medical science belongs to primary disease categories such as " lumbago and skelalgia ", " arthromyodynia ", " lumbar and pedal pain ", think that its cause of disease fails with congenital deficiency of kidney-QI, kidney qi and forced labour is impairment of the kidney relevant, with the heresy invasion and attack that suffer wound, chronic strain and wind-engaging cold-damp repeatedly etc., certain relation is arranged all in addition.Main pathomechanism be suffer from a deficiency of the kidney solid, wind-cold damp pathogen resistance network, coagulation of QI-blood, battalion must not defend declare logical so that waist lower limb numbness resistance pain.
This class treatment of diseases can be divided conservative therapy, operative treatment two big classes at present.1. conservative treatment comprises for oral administration, the external treatment of Chinese medicine, also comprises massage, acupuncture or the like.The clinical prescription that is used for lumbago and skelalgia treatment is a lot, have continue to use ancient prescription as: Radix Angelicae Pubescentis et Herba Taxilli Decoction, three types of Arthralgia decoction, BUYANG HUANWU TANG are waited for; The report that has certainly plan side as: dredging DU Meridian blood activating decoction, Men Shi activation soup, five rattans drink, removing obstruction from collaterals pain relieving soup, blood circulation and channel invigorating soup, red deer dredging DU Meridian sheet, medicine powder for treating bone Bi-syndrome, wait.2. part degeneration lumbar disc disease such as intervertebral disc prolapse, lumbar spinal stenosis etc. are also taked operative therapy, treatments such as row disc removal, spinal canal decompression.
Existing problems: 1. clinical prescription is numerous and mixed and disorderly, actual efficacy is very different, 2. medicine typing lacks unified standard, 3. prescription is limited to a card one type mostly, or be limited to a ground one disease, lack the value of applying, though 4. naturopathy such as massage, acupuncture can relief of symptoms, but can not effect a permanent cure by comprehensively regulating, patient's symptom is often delayed time and is sent out, though 5. operative treatment can be removed factors such as nerve compression, many complication such as nerve injury, adhesion, spinal column unstability are also arranged, many patients can not relief of symptoms.
Summary of the invention
Goal of the invention: first purpose of the present invention is to provide a kind of Chinese medicine composition for the treatment of lumbago and skelalgia, this Chinese medicine composition is at the pathogenic characteristic of primary disease deficiency in origin and excess in superficiality, energy strengthening vital QI to eliminate pathogenic factors, reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease, can obviously improve patient's blood stasis due to renal deficiency, through BI-syndrome involved the blood vessels resistance syndrome, comprise that lumbago, the soreness of waist, lower limb are ached, numb, movable unable, intermittent limping etc.
Second purpose of the present invention is for a kind of preparation method for the treatment of the Chinese medicine composition of lumbago and skelalgia is provided.
Technical scheme: in order to solve above-mentioned first purpose, the technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of lumbago and skelalgia, it comprises the raw material of following weight portion: Radix Dipsaci 8～12g, Rhizoma Cibotii 8～12g, Ramulus Mori 10～15g, Caulis Spatholobi 10～15g, Eupolyphaga Seu Steleophaga 8～12g, Pheretima 8～12g, Scolopendra 8～12g, Radix Aconiti Preparata 4～8g, Radix Aconiti Kusnezoffii Preparata 4～8g, Semen Sinapis Albae 4～8g, Herba Epimedii 8～12g, Herba Pyrolae 12～18g, SHENGCAO 8～12g.
Preferably, the consumption of described each raw material is respectively: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, Scolopendra 10g, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, SHENGCAO 10g.
In order to solve above-mentioned second purpose, the technical solution adopted in the present invention is: a kind of preparation method for the treatment of the Chinese medicine composition of lumbago and skelalgia, and it may further comprise the steps:
(1) prescription takes by weighing each raw material Radix Dipsaci, Rhizoma Cibotii, Ramulus Mori, Caulis Spatholobi, Eupolyphaga Seu Steleophaga, Pheretima, Scolopendra, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Semen Sinapis Albae, Herba Epimedii, Herba Pyrolae, SHENGCAO by weight, and is standby;
(2) each raw material in the step (1) is decocted with water twice, it is 2 times of raw material total amount that head is fried in shallow oil amount of water, soaks 10～30 minutes, and decocting time 30～40 minutes leaches medicinal liquid; Two to fry in shallow oil amount of water be 1 times of raw material total amount, and decocting time 15～20 minutes leaches medicinal liquid, and boiling medicine with head promptly gets described Chinese medicine composition after liquid mixes.
Chinese medicine composition of the present invention is also referred to as the continuous ridge drink of celestial dragon, it can make any dosage form that comprises that described medicine is formed, be preferably peroral dosage form, it is that on the pharmacy meaning all can supply oral dosage form: water decoction, honeyed pill, condensed water honeyed pill, the watered pill, granule, capsule, tablet, powder, unguentum, oral liquid etc. are preferably water decoction.
The present invention comes from Chinese medical theory, sums up clinical practice experience for many years, has been developed into the continuous ridge drink of the celestial dragon of this Chinese medicine composition prescription, and at the pathogeny of person in middle and old age's lumbago and skelalgia deficiency in origin and excess in superficiality, the medicine prescription is selected in treating both the principal and the secondary aspects of a disease at the same time; Can strengthening vital QI to eliminate pathogenic factors, reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease, can obviously improve patient's blood stasis due to renal deficiency, through BI-syndrome involved the blood vessels resistance syndrome, comprise that lumbago, the soreness of waist, lower limb are ached, numb, movable unable, intermittent limping etc.This class illness has comprised the described lumbar degenerative spondylitis of modern medicine, prolapse of lumbar intervertebral disc, lumbar spinal stenosis, lumbar spondylolisthesis, myofascitis of back, lumbar muscle strain, piriformis syndrome, superior giuteus nerve neuritis etc.Be particularly useful for treating person in middle and old age's lumbago and skelalgia patient.
Beneficial effect: compared with prior art, advantage of the present invention is:
1, said composition is pure Chinese medicinal preparation, and is cheap, has no side effect, and preparation, taking convenience are suitable for promoting the use of;
2, the prescription prescription is rational in infrastructure, and compatibility is rigorous: in the side is monarch drug with Rhizoma Cibotii, Herba Epimedii, Radix Dipsaci liver and kidney tonifying, the strong muscle of bone strengthening; Minister is dispersed yin channel wind and cold, is searched and pick rheumatism of muscles and bones, Eupolyphaga Seu Steleophaga, Pheretima, Scolopendra expel wind to dredge collateral in addition with Radix Aconiti, Semen Sinapis Albae; Assistant is with the heresy of Caulis Spatholobi, Herba Pyrolae promoting blood circulation and stopping pain, temperatureization yin channel; Again with Ramulus Mori, SHENGCAO temperature promoting blood circulation, and help and dispel the wind, all medicines are pulled together, and make that Liver and kidney is mended, QI and blood is logical, ailment said due to cold or exposure is dispelled, strengthening vital QI to eliminate pathogenic factors, and treating both the principal and the secondary aspects of a disease at the same time, and all diseases must be separated;
3, the clinical application practice confirmation is evident in efficacy, and we are used for the treatment of person in middle and old age's lumbago and skelalgia, and clinical observation result for many years can be accelerated the improvement of symptom, and effect is good;
4, for some heavier lumbar degenerative diseases person that has the operative indication, we find through long-term clinical observation after surgery in conjunction with this prescription oral medication, can obviously accelerate the alleviation of postoperative symptom, reduce the appearance of postoperative complication.
The specific embodiment
Below routine by experiment beneficial effect of further setting forth Chinese medicine composition of the present invention (being also referred to as the continuous ridge drink of celestial dragon).
Experimental example 1:
Person in middle and old age's property prolapse of lumbar intervertebral disc in the period of the continuous ridge drink of the celestial dragon treatment 1995～1998 causes lumbago and skelalgia 48 examples.Medicinal: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, 2 of Scolopendras, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, SHENGCAO 10g.Decocting, every day 1 dose of 2 decoction being taken warmly, 2 weeks were 1 course of treatment, totally 1～3 course of treatment.During the treatment, advise patient's drowsiness plank bed to have a rest.
The result: 48 routine patients all followed up a case by regular visits to 6 months to 3 years.Cure 22 examples, cure rate reaches healing person's 2 examples 45.83%, 1 course of treatment, reaches healing person's 11 examples 2 courses of treatment, reaches healing person's 9 examples 3 courses of treatment; Significantly improvement 23 examples account for 47.92%; Effective 3 examples; Total effective rate is 100%.Modern pharmacological research confirms that medicines such as Radix Rehmanniae Preparata, Caulis Spatholobi, Pheretima, Eupolyphaga Seu Steleophaga all have the activation and the antiplatelet coagulation of pair plasminogen; The Cortex Eucommiae, Herba Pyrolae have antiinflammatory action; Illustrate with modern medicine and eliminate the nerve root inflammation that alleviating outstanding vertebral pulp is consistent to the treatment mechanism of nerve root compression.
Experimental example 2: surgeon's knot heals up and obeys the clinical trial that the continuous ridge drink of celestial dragon is treated the degeneration lumbar spinal stenosis.
Adopt random packet, parallel control, completely random method for designing, observe the 62 routine patients that acquisition is followed up a case by regular visits in the period of 2003～2005, wherein perform the operation and organize 36 examples in conjunction with the treatment of the continuous ridge drink of the oral celestial dragon of postoperative, it is the continuous ridge drink of oral celestial dragon that the postoperative fasting is removed, prescription: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, 2 of Scolopendras, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, SHENGCAO 10g.Usage: be decocted in water for oral dose, 1 dose of day, divide clothes 2 times.2 weeks were a course of treatment, observe the curative effect after continuous 2 courses of treatment.Surgery alone matched group 26 examples.Use Oswestry dysfunction index efficacy evaluation and treat the front and back scoring, calculate acceptance rate.The acceptance rate of treatment group as a result 91.7%, 73.1%, two group of difference of matched group acceptance rate has significance, P＜0.05%, and the treatment group doing well,improving time is obviously early than matched group.Conclusion: the continuous ridge drink of celestial dragon is oral, and to be used for the effect of degeneration lumbar spinal stenosis aftertreatment good, and doing well,improving is rapid.
Sound out its reason: by operative treatment, can thoroughly remove the compressing of nerve or nerve root, enlarge the space of canalis spinalis and nerve root canal, the stability of constructing the disease vertebra again reaches to control its target purpose; And postoperative gives Chinese herb decoction and executes and control, and can recover the stable of environment in the canalis spinalis again, recovers neural physiological function, improves symptom, reaches the purpose with Zhi Qiben.Press and inflammatory reaction through secular serious card, pathological change has in various degree taken place in nervous tissue, and the interior environment of canalis spinalis gets muddled, and only depends on decompression and structure to reinvent and can not fundamentally improve symptom rapidly; And deficiency in origin is not healed, and postoperative is hindered healthy energy again, adds void on the void; Shou Shu intervention makes the patient feel frustrated blood trouble and new symptom occur again in addition, therefore at this pathogenesis, emphasize to give after surgery the Coryza Treated by Syndrome Differentiation of Chinese medicine, being intended to mark effects a permanent cure, recover the stable of the inside and outside environment of canalis spinalis, impel the patient can recover healthy energy and physiological function in a short time, this improvement and prognosis for pathomechanism has important effect.
Experimental example 3: the continuous ridge drink of celestial dragon closes the clinical trial of methyl meticortelone (MP) to the protection of lumbar vertebra postoperative nerve root injury.
Method: selected case is totally 44 examples, male's 27 examples wherein, women's 17 examples; Age is at 28 years old～72 years old, average out to 47.77 ± 11.25 years old.According to the difference of the concrete medication of postoperative, be divided into MP at random and organize (A group), MP adds the continuous ridge drink group (B group) of celestial dragon, and it is oral promptly to give the continuous ridge drink of celestial being dragon after the postoperative releasing fasting, and 1 dose of every day, day obeys 2 times, and serveing on 7d is 1 course of treatment, drug withdrawal after shared 2 courses of treatment.The disconnected ridge drink of celestial dragon prescription: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, 2 of Scolopendras, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, Radix Glycyrrhizae 10g.The the 1st, 7,15 day after surgery and postoperative the 1st, March are carried out the curative effect assessment with VAS and JOA scoring respectively.The result: all patients in 2 weeks after surgery VAS and before the JOA score value all obviously is better than art; But comparing difference not statistically significant (P＞0.05) between two groups of A, B.3 months B of postoperative group VAS score value and postoperative January, the JOA scoring in March all obviously is better than the A group, and difference has statistical significance (P＜0.05).Conclusion: MP can improve nerve root edema symptom in a short time for the damage of lumbar vertebra postoperative spinal nerve root, reduces the postoperative root pain.With the celestial imperial long-term efficacy that continues after ridge drink use in conjunction can significantly improve lumbar surgery, help the recovery of patient function of nervous system.Prompting Chinese medicine may play a role in the recovery of nerve root injury.Use in conjunction particularly acts on obviously on to the late result of spinal nerve root damage.
Come further to set forth the present invention by the following examples.
Embodiment 1: get each raw material: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, Scolopendra 10g, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, SHENGCAO 10g, decoct with water twice, it is 2 times of raw material total amount that head is fried in shallow oil amount of water, soaked 10 minutes, decocting time 30 minutes leaches medicinal liquid; Two to fry in shallow oil amount of water be 1 times of raw material total amount, and decocting time 15 minutes leaches medicinal liquid, and boiling medicine with head promptly gets described Chinese medicine composition after liquid mixes.
Embodiment 2: get each raw material: Radix Dipsaci 8g, Rhizoma Cibotii 8g, Ramulus Mori 10g, Caulis Spatholobi 10g, Eupolyphaga Seu Steleophaga 8g, Pheretima 8g, Scolopendra 8g, Radix Aconiti Preparata 4g, Radix Aconiti Kusnezoffii Preparata 4g, Semen Sinapis Albae 4g, Herba Epimedii 8g, Herba Pyrolae 12g, SHENGCAO 8g, decoct with water twice, it is 2 times of raw material total amount that head is fried in shallow oil amount of water, soaked 20 minutes, decocting time 35 minutes leaches medicinal liquid; Two to fry in shallow oil amount of water be 1 times of raw material total amount, and decocting time 15 minutes leaches medicinal liquid, and boiling medicine with head promptly gets described Chinese medicine composition after liquid mixes.
Embodiment 3: get each raw material: Radix Dipsaci 12g, Rhizoma Cibotii 12g, Ramulus Mori 15g, Caulis Spatholobi 15g, Eupolyphaga Seu Steleophaga 12g, Pheretima 12g, Scolopendra 12g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Semen Sinapis Albae 8g, Herba Epimedii 12g, Herba Pyrolae 18g, SHENGCAO 12g, decoct with water twice, it is 2 times of raw material total amount that head is fried in shallow oil amount of water, soaked 30 minutes, decocting time 40 minutes leaches medicinal liquid; Two to fry in shallow oil amount of water be 1 times of raw material total amount, and decocting time 20 minutes leaches medicinal liquid, and boiling medicine with head promptly gets described Chinese medicine composition after liquid mixes.
Claims (3)
1. Chinese medicine composition for the treatment of lumbago and skelalgia, it is characterized in that it comprises the raw material of following weight portion: Radix Dipsaci 8～12g, Rhizoma Cibotii 8～12g, Ramulus Mori 10～15g, Caulis Spatholobi 10～15g, Eupolyphaga Seu Steleophaga 8～12g, Pheretima 8～12g, Scolopendra 8～12g, Radix Aconiti Preparata 4～8g, Radix Aconiti Kusnezoffii Preparata 4～8g, Semen Sinapis Albae 4～8g, Herba Epimedii 8～12g, Herba Pyrolae 12～18g, SHENGCAO 8～12g.
2. a kind of Chinese medicine composition for the treatment of lumbago and skelalgia according to claim 1, it is characterized in that the consumption of described each raw material is respectively: Radix Dipsaci 10g, Rhizoma Cibotii 10g, Ramulus Mori 12g, Caulis Spatholobi 12g, Eupolyphaga Seu Steleophaga 10g, Pheretima 10g, Scolopendra 10g, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Semen Sinapis Albae 6g, Herba Epimedii 10g, Herba Pyrolae 15g, SHENGCAO 10g.
3. a kind of preparation method for the treatment of the Chinese medicine composition of lumbago and skelalgia according to claim 1 and 2 is characterized in that it may further comprise the steps:
(1) prescription takes by weighing each raw material Radix Dipsaci, Rhizoma Cibotii, Ramulus Mori, Caulis Spatholobi, Eupolyphaga Seu Steleophaga, Pheretima, Scolopendra, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Semen Sinapis Albae, Herba Epimedii, Herba Pyrolae, SHENGCAO by weight, and is standby;
(2) each raw material in the step (1) is decocted with water twice, it is 2 times of raw material total amount that head is fried in shallow oil amount of water, soaks 10～30 minutes, and decocting time 30～40 minutes leaches medicinal liquid; Two to fry in shallow oil amount of water be 1 times of raw material total amount, and decocting time 15～20 minutes leaches medicinal liquid, and boiling medicine with head promptly gets described Chinese medicine composition after liquid mixes.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168939A (en) * | 2015-10-19 | 2015-12-23 | 济南邦文医药科技有限公司 | Traditional Chinese medicinal composition for treating kidney and body deficiency type gynecological postoperative lumbar pain |
| CN106236861A (en) * | 2016-09-09 | 2016-12-21 | 成都市飞龙水处理技术研究所 | A kind of for decoction medicine treating lumbago and skelalgia and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840100A (en) * | 2006-01-11 | 2006-10-04 | 张国柱 | Tendon-relaxing pain-relieving Chinese herbal powder |
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- 2010-10-21 CN CN2010105142532A patent/CN101953908A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840100A (en) * | 2006-01-11 | 2006-10-04 | 张国柱 | Tendon-relaxing pain-relieving Chinese herbal powder |
Non-Patent Citations (1)
| Title |
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| 《江苏中医药》 20061231 陈巨鹏等 手术结合口服中药治疗退行性腰椎管狭窄症36例临床观察 第37-38页 1-3 第27卷, 第5期 2 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168939A (en) * | 2015-10-19 | 2015-12-23 | 济南邦文医药科技有限公司 | Traditional Chinese medicinal composition for treating kidney and body deficiency type gynecological postoperative lumbar pain |
| CN106236861A (en) * | 2016-09-09 | 2016-12-21 | 成都市飞龙水处理技术研究所 | A kind of for decoction medicine treating lumbago and skelalgia and preparation method thereof |
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Application publication date: 20110126 |