CN101380425A - Arthrosis pill and production method thereof - Google Patents

Arthrosis pill and production method thereof Download PDF

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CN101380425A
CN101380425A CNA2008101717355A CN200810171735A CN101380425A CN 101380425 A CN101380425 A CN 101380425A CN A2008101717355 A CNA2008101717355 A CN A2008101717355A CN 200810171735 A CN200810171735 A CN 200810171735A CN 101380425 A CN101380425 A CN 101380425A
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radix
pill
parts
arthrosis
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CN101380425B (en
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权吉太
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Abstract

The invention discloses a joint pill and a manufacture method thereof and solves the problem that the existing technology has high cost, toxic and side effect, etc. The joint pill comprises the following twenty three components by weight proportion: 17-22 parts of buckhorn, 8-12 parts of ginseng, 25-35 parts of milk veteh, 18-23 parts of angelica, 18-23 parts of the rhizome of large-headed atractylodes, 22-30 parts of zaocys dhumnades, 15-20 parts of fructus psoraleae, 18-23 parts of achyranthes, 22-30 parts of cassia twig, etc. The preparation method of the joint pill comprises the following steps: 1) the extraction by alcohol; 2) distillation; 3) decoction; 4) drying in the shade and smashing; 5) concentration; 6) smashing after drying in the vacuum; the long-term clinical test proves that the joint pill prepared by the twenty there medicines can rapidly regulate a plurality of diseases such as ache, stiffness, tumidness and mobility-handicapped caused by arthritis, thus achieving the effect of expelling wind and removing damness and thoroughly healing rheumatism.

Description

Arthrosis pill and preparation method thereof
Technical field
The present invention relates to the arthralgic Chinese medicine of a kind of treatment.
Background technology
Arthritis is a kind of common chronic disease, and modal is two kinds of osteoarthritis and rheumatoid arthritis, and the present arthritic of China estimates at more than 100,000,000, and number is also in continuous increase.
Arthritis is meant the arthritis pathological changes that is caused by inflammation, infection, wound or other factors, belongs to rheumatism subject disease.Its principal character is redness and swelling of joints, heat, pain and dysfunction.A lot of diseases all can cause the arthritis pathological changes, below several comparatively common in clinical.
Rheumatism: it is with the joint symmetry, recurrent, migration pain is the connective tissue disease of characteristics, and this disease can be caused by upper respiratory tract infection, with heating, the tired power of body, acrohyperhidrosis, numbness, pain or paraesthesia continue because of the increasing of periosteum and articular cavity transudate, and redness and swelling of joints occurs, burning pain, maximum complication is rheumatic heart disease.
Rheumatoid: it is that a kind of articular muscle is recurrent, and the autoimmune disease of osteoclasia occurs in the finger of human body far-end, toe joint, this is much more sick and autoimmunity is low, the regulatory function disorder, dismutase lacks, the endocrine disturbance, heredity has close ties, see the women, 70% belongs to latent gradually property morbidity more, and little local joint has slight pain and General Symptoms is not obvious during beginning, develop slower, alleviate and alternately appearance of recurrence, increase the weight of 10% acute onset gradually, suddenly heating, systemic pain, weak, redness and swelling of joints, swelling, joint deformity and tetanic, the rheumatoid subcutaneous nodule, amyotrophy, vasculitis and the high viscosity syndrome is quite a few sees.
Cervical spondylosis, lumbar vertebra hyperosteogeny and lumbar intervertebral disc are deviate from, lumbar muscle strain.
Cervical spondylosis is that vertebral body has bony spur because the cervical intervertebral disk degeneration becomes flexible between vertebral body, the compressing and the root that excites nerve, spinal cord, autonomic nerve, vertebral artery etc. cause that a series of symptoms are a kind of senile degenerative disease of feature, show as dizziness, dimmed tinnitus, the neural aching and tired pain of the shoulder back of the body, strong, the arm numbness of the fingers is that main, chronic strain and progressive regression is pathogenetic two key factors of cervical vertebra, sees more than 40 years old more.
Lumbar vertebra is a physical activity scope maximum, bears a heavy burden at most.Damaged easily, the influence of bad climate, dyshormonia, blood fortune obstacle, pathobolism all can cause lumbar vertebrae bone to increase, and long-time waist is ached, form the range of activity that the bone bridge can have influence on lumbar vertebra as bony spur, the dysfunction of waist occurs, oppressed sciatic nerve as outgrowth position and buttocks can occur again, radiated pain under the lateral behind the thigh.
Scapulohumeral periarthritis is a kind of abbreviation with the common shoulder joint aseptic inflammation of person in middle and old age, and its typical symptoms is in early days because of the hyperemia of local joint, edema, inflammatory exudate etc., the nerve around stimulating and obvious pain occurs.Later stage is because of arthritis, and the adhesion of tendon ligament and the limitation of activity of shoulder joint occurs is mainly in a side, also has many sides simultaneously sore, can not lift certainly and can not comb one's hair with the Ipsilateral upper limb, and the difficulty of wearing the clothes is characteristics.This disease is revealed shoulder at night because of being more common in clinically, is subjected to the ailment said due to cold or exposure onset, also causes local moving obstacle onset because of the local adhesion of pain.
Postpartum rheumatic is all with women puerperal, and in age of sucking and the muscle that takes place, finger tip, joint aches wood are main pain, are referred to as postpartum rheumatic.It is because the women causes passages through which vital energy circulates puerperal, and the damage of QI and blood is run off and can not very fast recovery, causes QI and blood to be lost in interior, can not resist exopathogen, be affected by the cold pathogen this moment, reside in muscle, joint part, the operation of numbness choke blood can be fallen ill, primary disease is carrying out property of chronic disease more to be increased the weight of, and showing as brothers feels cold, and claps wind, aching pain of muscles, spasm, numb limbs and tense tendons, joint stuffiness and joint ache, even swelling can not out-of-bed activities.
In the prior art, according to PD degree difference, arthritic treatment comprises Drug therapy, auxiliary treatment and operative treatment.Wherein, operative treatment has developed into the patient in late period for disease, a kind of good treatment means of can yet be regarded as, but this method expense height, and effect is undesirable, and the misery that causes to the patient is also bigger; Arthritic auxiliary treatment is that patient's joint disease is in early, during mid-term, a kind of method that cooperates Drug therapy to use.Auxiliary treatment is exactly our physical therapy and physical exercise therapy of saying at ordinary times, such as serial of methods such as diathermy, massage, massage, acupuncture.Though this method can alleviate the partial discomfort of patient, arthritis there is not the curative effect of essence; And mostly Drug therapy is to adopt nonsteroidal antiinflammatory drug analgesic alleviating pain just, or carry out injection for curing with hormone medicine, though these two kinds of medicines are energy reduction of patient misery on certain program, but it can not really stop the development of the arthritis state of an illness, and toxic and side effects is bigger, so can not life-time service.
Summary of the invention
For overcoming above-mentioned defective, the object of the present invention is to provide a kind of therapeutic effect is good, have no side effect arthrosis pill and manufacture method.
For achieving the above object, arthrosis pill of the present invention is characterized in that it being that raw material by following weight portion is made:
Cornu Cervi 17-22 Radix Ginseng 8-12 Radix Astragali 25-35 Radix Angelicae Sinensis 18-23
Rhizoma Atractylodis Macrocephalae 18-23 Zaocys 22-30 Fructus Psoraleae 15-20 Radix Achyranthis Bidentatae 18-23
The nine 18-23 Radix Rehmanniae Preparata 18-23 Eupolyphaga Seu Steleophaga 13-19 of the Ramulus Cinnamomi 22-30 Qin
Pheretima 30-38 Cortex Eucommiae 40-47 Radix Salviae Miltiorrhizae 27-33 Fructus Chaenomelis 22-30
Radix Et Caulis Acanthopanacis Senticosi 46-54 Semen Persicae (parched) 18-23 Radix Stephaniae Tetrandrae 10-16 8-12 recklessly far away
Rhizoma Gastrodiae 8-12 Radix Glycyrrhizae 26-33 Rhizoma Dioscoreae Nipponicae 17-23.
Particularly, make by the raw material of following weight portion:
Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5
Zaocys 26 Fructus Psoraleaes 17 Radix Achyranthis Bidentataes 21.5 Ramulus Cinnamomi 26 play 9 21.5
Radix Rehmanniae Preparata 21.5 Eupolyphaga Seu Steleophagas 16 Pheretimas 34.5 Cortexs Eucommiae 43 Radix Salviae Miltiorrhizaes 30
Fructus Chaenomelis 26 Radix Et Caulis Acanthopanacis Senticosis 50 Semen Persicae (parched)s 21.5 Radix Stephaniae Tetrandrae 13 Hus 10 far away
Rhizoma Gastrodiae 10 Radix Glycyrrhizaes 30 Rhizoma Dioscoreae Nipponicae 20.
For achieving the above object, the manufacture method of arthrosis pill of the present invention comprises the steps:
1) alcohol extraction:
Get the raw material of following weight portion: Fructus Psoraleae 17 Radix Achyranthis Bidentataes 21.5 Fructus Chaenomeliss 26 Ramulus Cinnamomi 26 Radix Stephaniae Tetrandrae 13 Rhizoma Dioscoreae Nipponicae 20 75 degree ethanol 600-1000
Above-mentioned raw materials is immersed in the above-mentioned ethanol one hour heats under the final vacuum condition, heating-up temperature 40-60 degree, withdrawal liquid is standby;
2) distillation
Get the raw material of following weight portion: Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5 water are an amount of
Be soaked in water 2 hours after above-mentioned Chinese medicine cleaned, heating extraction, heating-up temperature 40-60 degree distill about 2 hours, and the liquid that distills gained is standby;
3) decoct
Get the raw material of following weight portion: Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Zaocyss 26
The Qin's 9 21.5 Radix Rehmanniae Preparata, 21.5 Eupolyphaga Seu Steleophagas, 16 Pheretimas, 34.5 Cortexs Eucommiae, 43 Radix Salviae Miltiorrhizaes 30
Radix Et Caulis Acanthopanacis Senticosi 50 Radix Glycyrrhizaes 30 Semen Persicae (parched)s 21.5 water are an amount of
Heating extraction, heating-up temperature 40-60 degree be soaked in water 24 hours after above-mentioned Chinese medicine cleaned; The liquid that decocts the back gained is standby.
4) get the raw material of following weight portion: 10 Rhizoma Gastrodiaes 10 recklessly far away
Above-mentioned Chinese medicine is cleaned the back of drying in the shade to be pulverized standby
5) with above-mentioned steps 1), 2), 3) to be condensed into ointment under vacuum condition stand-by for the medicinal liquid produced;
6) after ointment that step 4) and step 5) is made mixes, crushed after being dried under vacuum.
Traditional Chinese medical science principle according to " pain then obstructed, general rule not bitterly ", arthrosis pill of the present invention is made up of above-mentioned 23 herbal medicines, the pain that various arthritis is caused through secular clinical trial certificate, send out many diseases such as deadlock, swelling, moving difficulty, can reach the effect of adjustment rapidly, reach expelling wind and removing dampness, thoroughly cure rheumatismal effect.Since beginning in 1998, to adopt arthrosis pill and treat various arthritis and begin, be 60 days the course of treatment, laboratory observation, after the medication, the pain and the swelling in patient joint fade away, and action is convenient, and effective percentage accounts for more than 90%, all obtains satisfied effect.
The specific embodiment
Arthrosis pill of the present invention according to the traditional Chinese medical science principle of " pain then obstructed, general rule not bitterly ", is to be made by the raw material of following weight portion:
Cornu Cervi 17-22 Radix Ginseng 8-12 Radix Astragali 25-35 Radix Angelicae Sinensis 18-23
Rhizoma Atractylodis Macrocephalae 18-23 Zaocys 22-30 Fructus Psoraleae 15-20 Radix Achyranthis Bidentatae 18-23
The nine 18-23 Radix Rehmanniae Preparata 18-23 Eupolyphaga Seu Steleophaga 13-19 of the Ramulus Cinnamomi 22-30 Qin
The Pheretima 30-38 Cortex Eucommiae 4 0-47 Radix Salviae Miltiorrhizae 27-33 Fructus Chaenomelis 22-30
Radix Et Caulis Acanthopanacis Senticosi 46-54 Semen Persicae (parched) 18-23 Radix Stephaniae Tetrandrae 10-16 8-12 recklessly far away
Rhizoma Gastrodiae 8-12 Radix Glycyrrhizae 26-33 Rhizoma Dioscoreae Nipponicae 17-23.
Motherland's medical science is thought the pain of this disease because be affected by the cold, deficiency of the liver and kindey, muscle arteries and veins lose support due to, not only there is wind-damp dispelling in joint nine, and the relaxing muscles and tendons and activating QI and blood in the collateral medicine forces heresy to go out, and is equipped with invigorating the liver and kidney, the medicine of bone and muscle strengthening and consolidating, this type of patient only obeys the medicine of 2-3 courses of treatment and just can cure.The pain that various arthritis is caused through secular clinical trial certificate, send out many diseases such as deadlock, swelling, moving difficulty, can reach the effect of adjustment rapidly, reach expelling wind and removing dampness, thoroughly cure rheumatismal effect.
Above-mentioned raw material, can according to different syndromes in above-mentioned scope feelings plus-minuss, through long-term clinical trial certificate, preferably make by the raw material of following weight parts:
Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5
Zaocys 26 Fructus Psoraleaes 17 Radix Achyranthis Bidentataes 21.5 Ramulus Cinnamomi 26 Qin 9 21.5
Radix Rehmanniae Preparata 21.5 Eupolyphaga Seu Steleophagas 16 Pheretimas 34.5 Cortexs Eucommiae 43 Radix Salviae Miltiorrhizaes 30
Fructus Chaenomelis 26 Radix Et Caulis Acanthopanacis Senticosis 50 Semen Persicae (parched)s 21.5 Radix Stephaniae Tetrandrae 13 Hus 10 far away
Rhizoma Gastrodiae 10 Radix Glycyrrhizaes 30 Rhizoma Dioscoreae Nipponicae 20.
The manufacture method of arthrosis pill of the present invention is described in detail in detail with above-mentioned optimum weight portion raw material below, comprises the steps:
1) alcohol extraction:
Get the raw material of following weight portion: Fructus Psoraleae 17 Radix Achyranthis Bidentataes 21.5 Fructus Chaenomeliss 26 Ramulus Cinnamomi 26 Radix Stephaniae Tetrandrae 13 Rhizoma Dioscoreae Nipponicae 20 75 degree ethanol 600-1000
Above-mentioned raw materials was immersed in the above-mentioned ethanol after one hour, heats under vacuum condition, heating-up temperature 40-60 degree treats that ethanol volatilization back withdrawal liquid is standby;
2) distillation
Get the raw material of following weight portion: Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5 water are an amount of
Be soaked in water 2 hours after above-mentioned Chinese medicine cleaned, heating extraction, heating-up temperature 40-60 degree distill about 2 hours, and it is standby to get the liquid that distills gained;
3) decoct
Get the raw material of following weight portion: Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Zaocyss 26
The Qin's 9 21.5 Radix Rehmanniae Preparata, 21.5 Eupolyphaga Seu Steleophagas, 16 Pheretimas, 34.5 Cortexs Eucommiae, 43 Radix Salviae Miltiorrhizaes 30
Radix Et Caulis Acanthopanacis Senticosi 50 Radix Glycyrrhizaes 30 Semen Persicae (parched)s 21.5 water are an amount of
Heating extraction, heating-up temperature 40-60 degree be soaked in water 24 hours after above-mentioned Chinese medicine cleaned; The liquid that decocts the back gained is standby.
4) get the raw material of following weight portion: 10 Rhizoma Gastrodiaes 10 recklessly far away
Above-mentioned Chinese medicine is cleaned the back of drying in the shade to be pulverized standby
5) with above-mentioned steps 1), 2), 3) to be condensed into ointment under vacuum condition stand-by for the medicinal liquid produced;
6) after ointment that step 4) and step 5) is made mixes, crushed after being dried under vacuum.
Through above-mentioned steps, the medicated powder of gained can the pill agent, tablet or capsule, contains above-mentioned medicated powder 0.3 gram with every/ball/grain.
[usage and consumption] is oral, a 5/ball/grain, 2 to 3 times on the one, one after each meal.One and a half months is the course of treatment.
[function with cure mainly] expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, removing obstruction in the collateral to relieve pain.Be used for acute and chronic rheumatism, rheumatoid, rheumatic arthritis, scapulohumeral periarthritis, cervical region myofibrositis, proliferative arthritis, chronic myofibrositis, waist and leg ache, numb hand and foot, ventilation, the sciatica etc. wanted.
Observed result
(1), the treatment by Chinese herbs arthromyodynia clinical research guideline of efficacy assessment standard Ministry of Public Health formulation in 1993 is formulated.
1, clinical cure: symptom all disappears, and it is normal that functional activity recovers, and main doctor trained in Western medicine is theoretical checks that physical and chemical index is normal.2, produce effects: symptomatology is eliminated or cardinal symptom is eliminated, and function of joint is recovered substantially, can participate in normal work or physical labor, and the physico-chemical examination index is normal substantially.3, effective: cardinal symptom is eliminated substantially, joint function recovery or have made marked progress, and main physico-chemical examination index makes moderate progress.4, invalid: with the treatment before compare the equal zero difference of each side index.
(2), comprehensive therapeutic effect: in this group 330 row, clinical produce effects 186 examples account for 56.3%, and effective 126 examples account for 38.2%, and invalid 18 examples account for 5.5%, and total effective rate is 94.5%, and obvious effective rate is 56.3%.
Disease The example number Produce effects Effectively Invalid Effective percentage
Rheumatic arthritis 67 46 33 0
Rheumatoid arthritis 91 49 41 1
Scapulohumeral periarthritis 57 25 15 5
Cervical spondylosis 59 34 19 6
Ventilation disease 31 20 8 3
Spondylitis of lumbar vertebra 25 12 10 3
Add up to 330 186 126 18 94.5%
(3) the symptom curative effect syndrome of cold-dampness blocking collaterals such as the back is heavy to whole body arthralgia, cold type of pain, swelling deadlock in morning of taking medicine improve significantly, and adopt statistical procedures, significant difference before and after the treatment
Sings and symptoms Pathology example number disappears Lose routine number Effective percentage (%)
Whole body arthralgia 96 92 95.8%
Morning, deadlock swelled and ache 34 31 91
Subcutaneous nodule 81 80 98.7%
Coolness of extremities waist cold type of pain 119 114 95.2%
(4) to erythrocyte sedimentation rate, anti-" 0 " and leukocytic influence
Arthrosis pill of the present invention has anti-" 0 " the reduction effect that makes the erythrocyte sedimentation rate that speeds and rising, and there is significant difference (p<0.01) in own control before and after the treatment.
1) to the influence of " erythrocyte sedimentation rate "
Based on the disease of rheumatism, main suit's coolness of extremities, pain in the low back and legs, morning deadlock, chemical examination erythrocyte sedimentation rate) 50mm/ hour, man, female patient 50 routine treatment targets, each 25 example is divided into two groups at random with binocular, one group of 25 5 of each oral arthrosis pill of the present invention of example, 3 times on the one, one after each meal; Another group 25 examples are thrown prednisone 45mg every days, and two groups each take one and a half months respectively, and the two symptom just has improvement, and (20mm/ hour, but after drug withdrawal January, clothes prednisone patient glucose recovery did not have this phenomenon and obey arthrosis pill patient of the present invention before take to erythrocyte sedimentation rate.
Medicine Case load (example) Day number of drug administration (my god) Dosage The preceding erythrocyte sedimentation rate of taking medicine Erythrocyte sedimentation rate after taking medicine Drug withdrawal is erythrocyte sedimentation rate after 30 days
Arthrosis pill of the present invention 25 45 4.5g/d 50mm/ hour <20mm/ hour <20mm/ hour
Prednisone 25 45 45mg/d 50mm/ hour <20mm/ hour 20mm/ hour
2) influence of antagonism " 0 "
Clinically based on the disease of rheumatic arthritis, articulations digitorum manus swelling, toe joint swelling, anti-" 0 "〉700 units, 140 routine patients are object, be divided into two groups with double blind random, every group is 70 examples, 5 of one group of each oral arthrosis pills of the present invention of every example, 3 times on the one, one after each meal, the every example of another group is thrown prednisone 45mg every day, takes one and a half months, the two transference cure respectively for two groups, anti-" 0 "<500 unit, but behind the drug withdrawal first quarter moon, clothes prednisone patient glucose recovery does not have this phenomenon and obey arthrosis pill person of the present invention before take medicine.
Medicine Case load (example) Day number of drug administration (my god) Dosage Resist 0 before taking medicine Resist 0 after taking medicine Drug withdrawal resisted 0 after 15 days
Arthrosis pill of the present invention 70 45 4.5g/d 700 units <500 units <500 units
Prednisone 70 45 45mg/d 700 units <500 units <700 units
3) to rheumatoid influence
Clinically with rheumatoid patient 100 examples, chemical examination rheumatoid factor (RF) positive is divided into two groups with double blind random, every group 50 example, 5 of one group of each oral arthrosis pills of the present invention, 3 times on the one, one after each meal; The every example of another group is thrown prednisone 45mg every day, takes three months, and the chemical examination rheumatoid factor becomes negative symptoms and disappears, but drug withdrawal is obeyed the prednisone patient and had the 40 human rheumatoid factors to become the positive after two months.
4) to the influence of rheumatism patient pain
Rheumatism patient 120 examples clinically, be divided into two groups with the double blinding machine, every group 60 example, 5 of one group of each oral arthrosis pills of the present invention, 3 times on the one, one after each meal, the every example clothes of another group indometacin 45m, the one and a half months of taking medicine, the two pain all disappears, but behind the drug withdrawal first quarter moon, take before the recovery of indometacin patient pain, do not have this phenomenon and take arthrosis pill person of the present invention.
Medicine Case load (example) Day number of drug administration (my god) Dosage The preceding symptom of taking medicine Symptom after taking medicine
Arthrosis pill of the present invention 60 45 4.5g/d Pain Pain disappears
Indometacin 60 45 45mg/d Pain Pain disappears
5 safety evaluatios
This shows that arthrosis pill of the present invention all has no adverse effects to liver, renal function, cell, hemoglobin, heart rate, blood pressure before and after organizing 330 routine patient treatments.Gastrointestinal tract is not had obvious irritation, liver, kidney is had no side effect, to human body have no drug resistance, no dependence, do not see other toxic and side effects.
Model case
Case 1
Thank to Hua Nan, 43 years old, lumbar muscle strain was suffered from 8 years in No. 6, new people alleyway, Road Inside Area, Harbin, and the pain increased recently, and cure many places, has little effect, and takes arthrosis pill one and a half months of the present invention, and symptom obviously alleviates.
Case 2
Li Li spends the woman, and 35 years old, the cadre of Shenyang municipal Party committee suffered from scapulohumeral periarthritis, has a strong impact on work, and left side shoulder presses down gently and pain, limitation of activity will occur.Not obvious through the Chinese and western drugs therapeutic effect, heavy when light during the state of an illness, the pain increased for climatic deterioration, takes course of treatment of arthrosis pill of the present invention, recovery from illness.
Case 3
Yang Li prunus mume (sieb.) sieb.et zucc. woman, 46 years old.No. 6, Changchun Kuancheng District the 13rd buildings.Seeking medical advice in the four directions, has little effect, and feels that often cervical region feels nervous, and with headache and dizzy, numb limbs and tense tendons etc. are diagnosed as cervical spondylosis on inspection, takes two courses of treatment of arthrosis pill of the present invention, and all transference cures see that the TV time does not longly have a dizzy sensation more yet.
Case 4
Wang Linnv, 46 years old, Tonghua City is stood always, and the street is healthy entrusted 1 group.Patient's extremities joint swelling pain 20 years, the state of an illness increases the weight of in the recent period, goes to a doctor after 1 month.Suffered from postpartum rheumatic before 20 years, occur the limb joint swelling and pain repeatedly, January, the extremities joint swelling pain increased the weight of because of being subjected to moist reproduction, and duplex is lifted limitation of activity on the joint, double knee joint pain, naked arthroncus, heavy, weak all over the body.Have a medical check-up dimly pale tongue, corpulent tongue is big, white and greasy fur, and deep and stringy pulse, two ankle joint and biped are not pitting edema.Chemical examination erythrocyte sedimentation rate 35mn/ hour, anti-" 0 " 800 units.Western medicine diagnose: rheumatic arthritis, tcm diagnosis: arthromyodynia, syndrome of cold-dampness blocking collaterals, treatment gives arthrosis pill of the present invention, each 5,3 times on the one, serve on one and a half months.Biped and hot-tempered arthroncus are all disappeared, and sleep, and two is just normal, red tongue, and tongue body is normal, and tongue fur is normal, thin white fur of tongue, two deep and stringy pulse.Check erythrocyte sedimentation rate 10mm/ hour, anti-" 0 " 200 units are discharged from hospital after recovery.
Above rheumatism, rheumatoid patient, through anti-" 0 ", erythrocyte sedimentation rate, after clapping the diagnosis of X-ray sheet, take one to three course of treatment of arthrosis pill of the present invention, effect has preferably appearred, the powerful curative effect of the passages through which vital energy circulates of arthrosis pill blood stasis dispelling resistance has confirmed that arthrosis pill not only has wind-damp dispelling, blood stasis dispelling cold expelling and the function of forcing heresy to go out, and has an invigorating the liver and kidney, bone and muscle strengthening improves the effect of body immunity, and is auxiliary with the only stasis of blood of invigorating blood circulation, the medicine of relaxing muscles and tendons and activating QI and blood in the collateral and reach " invigorate blood circulation earlier in dispelling, blood sector-style from going " effect, get final product produce effects a course of treatment, can cure three courses of treatment substantially.

Claims (3)

1, a kind of arthrosis pill is characterized in that it being that raw material by following weight portion is made:
Cornu Cervi 17-22 Radix Ginseng 8-12 Radix Astragali 25-35 Radix Angelicae Sinensis 18-23
Rhizoma Atractylodis Macrocephalae 18-23 Zaocys 22-30 Fructus Psoraleae 15-20 Radix Achyranthis Bidentatae 18-23
The nine 18-23 Radix Rehmanniae Preparata 18-23 Eupolyphaga Seu Steleophaga 13-19 of the Ramulus Cinnamomi 22-30 Qin
Pheretima 30-38 Cortex Eucommiae 40-47 Radix Salviae Miltiorrhizae 27-33 Fructus Chaenomelis 22-30
Radix Et Caulis Acanthopanacis Senticosi 46-54 Semen Persicae (parched) 18-23 Radix Stephaniae Tetrandrae 10-16 8-12 recklessly far away
Rhizoma Gastrodiae 8-12 Radix Glycyrrhizae 26-33 Rhizoma Dioscoreae Nipponicae 17-23.
2, arthrosis pill as claimed in claim 1 is characterized in that it being that raw material by following weight portion is made:
Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5
Zaocys 26 Fructus Psoraleaes 17 Radix Achyranthis Bidentataes 21.5 Ramulus Cinnamomi 26 Qin 9 21.5
Radix Rehmanniae Preparata 21.5 Eupolyphaga Seu Steleophagas 16 Pheretimas 34.5 Cortexs Eucommiae 43 Radix Salviae Miltiorrhizaes 30
Fructus Chaenomelis 26 Radix Et Caulis Acanthopanacis Senticosis 50 Semen Persicae (parched)s 21.5 Radix Stephaniae Tetrandrae 13 Hus 10 far away
Rhizoma Gastrodiae 10 Radix Glycyrrhizaes 30 Rhizoma Dioscoreae Nipponicae 20.
3, a kind of manufacture method of arthrosis pill is characterized in that, comprises the steps:
1) alcohol extraction:
Get the raw material of following weight portion: Fructus Psoraleae 17 Radix Achyranthis Bidentataes 21.5 Fructus Chaenomeliss 26 Ramulus Cinnamomi 26 Radix Stephaniae Tetrandrae 13 Rhizoma Dioscoreae Nipponicae 20 75 degree ethanol 600-1000
Above-mentioned raw materials is immersed in the above-mentioned ethanol one hour heats under the final vacuum condition, heating-up temperature 40-60 degree, withdrawal liquid is standby;
2) distillation
Get the raw material of following weight portion: Radix Angelicae Sinensis 21.5 Rhizoma Atractylodis Macrocephalaes 21.5 water are an amount of
Be soaked in water 2 hours after above-mentioned Chinese medicine cleaned, heating extraction, heating-up temperature 40-60 degree distill about 2 hours, and the liquid that distills gained is standby;
3) decoct
Get the raw material of following weight portion: Cornu Cervi 20 Radix Ginsengs 10 Radixs Astragali 30 Zaocyss 26
The Qin's 9 21.5 Radix Rehmanniae Preparata, 21.5 Eupolyphaga Seu Steleophagas, 16 Pheretimas, 34.5 Cortexs Eucommiae, 43 Radix Salviae Miltiorrhizaes 30
Radix Et Caulis Acanthopanacis Senticosi 50 Radix Glycyrrhizaes 30 Semen Persicae (parched)s 21.5 water are an amount of
Heating extraction, heating-up temperature 40-60 degree be soaked in water 24 hours after above-mentioned Chinese medicine cleaned; The liquid that decocts the back gained is standby;
4) get the raw material of following weight portion: 10 Rhizoma Gastrodiaes 10 recklessly far away
Above-mentioned Chinese medicine is cleaned the back of drying in the shade to be pulverized standby;
5) with above-mentioned steps 1), 2), 3) to be condensed into ointment under vacuum condition stand-by for the medicinal liquid produced;
6) after ointment that step 4) and step 5) is made mixes, crushed after being dried under vacuum.
CN2008101717355A 2008-10-24 2008-10-24 Arthrosis pill Expired - Fee Related CN101380425B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988858A (en) * 2012-11-16 2013-03-27 杨青吉 Traditional Chinese medicine composition for treating lumbus and leg pain and ischialgia
CN103070878A (en) * 2012-12-11 2013-05-01 上海浦东高星生物技术研究所 Compound Caulis Sinomenii tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1180831C (en) * 2003-02-09 2004-12-22 卫永生 New preparation of compound Chinese medicine for treating osteoarthritis and its preparation method
CN100450526C (en) * 2006-10-25 2009-01-14 雒宏志 Chinese medicinal formulation for treating rheumatic and rheumatoid disease

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988858A (en) * 2012-11-16 2013-03-27 杨青吉 Traditional Chinese medicine composition for treating lumbus and leg pain and ischialgia
CN103070878A (en) * 2012-12-11 2013-05-01 上海浦东高星生物技术研究所 Compound Caulis Sinomenii tablet

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