CN101868240A - 适合肠胃外给药的包含头孢烯衍生物的可溶剂型 - Google Patents

适合肠胃外给药的包含头孢烯衍生物的可溶剂型 Download PDF

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Publication number
CN101868240A
CN101868240A CN200880117449A CN200880117449A CN101868240A CN 101868240 A CN101868240 A CN 101868240A CN 200880117449 A CN200880117449 A CN 200880117449A CN 200880117449 A CN200880117449 A CN 200880117449A CN 101868240 A CN101868240 A CN 101868240A
Authority
CN
China
Prior art keywords
dosage form
ceftaroline
acid
ceftaroline fosamil
fosamil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880117449A
Other languages
English (en)
Chinese (zh)
Inventor
M·德希亚
Y·葛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40468354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101868240(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN101868240A publication Critical patent/CN101868240A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200880117449A 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型 Pending CN101868240A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97419407P 2007-09-21 2007-09-21
US60/974,194 2007-09-21
PCT/US2008/076920 WO2009039324A1 (en) 2007-09-21 2008-09-19 Soluble dosage forms containing cephem derivatives suitable for parenteral administration

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN2012104792814A Division CN102935065A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型
CN201410162742.4A Division CN103919720A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型

Publications (1)

Publication Number Publication Date
CN101868240A true CN101868240A (zh) 2010-10-20

Family

ID=40468354

Family Applications (3)

Application Number Title Priority Date Filing Date
CN200880117449A Pending CN101868240A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型
CN201410162742.4A Pending CN103919720A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型
CN2012104792814A Pending CN102935065A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201410162742.4A Pending CN103919720A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型
CN2012104792814A Pending CN102935065A (zh) 2007-09-21 2008-09-19 适合肠胃外给药的包含头孢烯衍生物的可溶剂型

Country Status (11)

Country Link
US (3) US20090082326A1 (enExample)
EP (2) EP2200618A4 (enExample)
JP (1) JP2010540448A (enExample)
KR (1) KR101599560B1 (enExample)
CN (3) CN101868240A (enExample)
AU (1) AU2008302201A1 (enExample)
BR (1) BRPI0816412A2 (enExample)
CA (1) CA2700263A1 (enExample)
MX (1) MX2010003112A (enExample)
RU (1) RU2537237C2 (enExample)
WO (1) WO2009039324A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104258403A (zh) * 2014-09-28 2015-01-07 苏州普罗达生物科技有限公司 一种西洛他唑组合物及其制备方法
WO2016008393A1 (zh) * 2014-07-14 2016-01-21 正大天晴药业集团股份有限公司 头孢罗膦氨基酸盐及其结晶

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012003201A (es) * 2009-09-21 2012-05-08 Astrazeneca Ab Composiciones y metodos para tratar infecciones bacterianas utilizando ceftarolina.
TWI679977B (zh) * 2011-10-19 2019-12-21 大塚製藥股份有限公司 口服溶液
KR20170038214A (ko) * 2015-09-30 2017-04-07 (주)아모레퍼시픽 당산 및 플라보노이드를 포함하는 항균용 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028355A (en) * 1974-01-23 1977-06-07 Smithkline Corporation Cephalosporin purification process
GB8729574D0 (en) * 1987-12-18 1988-02-03 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition
JP2761005B2 (ja) * 1988-11-02 1998-06-04 エーザイ株式会社 セファロスポリン含有注射用組成物
JPH02124822A (ja) * 1988-11-02 1990-05-14 Eisai Co Ltd セファロスポリン含有注射用組成物
DK0395219T3 (da) * 1989-03-30 1999-02-15 Pfizer Cephalosporiner og deres homologer, fremgangsmåde til deres fremstilling og farmaceutiske præparater
DE69004921T2 (de) * 1989-09-30 1994-05-05 Eisai Co Ltd Injizierbare Cephalosporinpräparate und ihre Anwendung.
JPH0840907A (ja) * 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
TW473479B (en) 1997-12-19 2002-01-21 Takeda Chemical Industries Ltd Phosphonocephem derivatives, their production and use
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
JP3586226B2 (ja) * 2000-08-10 2004-11-10 武田薬品工業株式会社 ホスホノセフェム化合物
CA2418614C (en) * 2000-08-10 2008-06-10 Takeda Chemical Industries, Ltd. Phosphonocephem compound
TWI344847B (en) * 2003-04-28 2011-07-11 Takeda Chemical Industries Ltd Composition for injection

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016008393A1 (zh) * 2014-07-14 2016-01-21 正大天晴药业集团股份有限公司 头孢罗膦氨基酸盐及其结晶
CN104258403A (zh) * 2014-09-28 2015-01-07 苏州普罗达生物科技有限公司 一种西洛他唑组合物及其制备方法
CN104258403B (zh) * 2014-09-28 2017-03-01 刘宗侠 一种西洛他唑组合物及其制备方法

Also Published As

Publication number Publication date
US20150196572A1 (en) 2015-07-16
BRPI0816412A2 (pt) 2017-05-16
CN102935065A (zh) 2013-02-20
RU2010115268A (ru) 2011-10-27
AU2008302201A1 (en) 2009-03-26
RU2537237C2 (ru) 2014-12-27
EP2200618A1 (en) 2010-06-30
WO2009039324A1 (en) 2009-03-26
US20120010180A1 (en) 2012-01-12
KR20100075942A (ko) 2010-07-05
US20090082326A1 (en) 2009-03-26
CN103919720A (zh) 2014-07-16
CA2700263A1 (en) 2009-03-26
EP2200618A4 (en) 2010-11-03
MX2010003112A (es) 2010-08-11
JP2010540448A (ja) 2010-12-24
EP2952195A1 (en) 2015-12-09
KR101599560B1 (ko) 2016-03-03

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Application publication date: 20101020