CN101851278B - B细胞激活因子拮抗剂及其制备方法与用途 - Google Patents

B细胞激活因子拮抗剂及其制备方法与用途 Download PDF

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CN101851278B
CN101851278B CN2010101839059A CN201010183905A CN101851278B CN 101851278 B CN101851278 B CN 101851278B CN 2010101839059 A CN2010101839059 A CN 2010101839059A CN 201010183905 A CN201010183905 A CN 201010183905A CN 101851278 B CN101851278 B CN 101851278B
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activating factor
cell
factor antagonist
cell activating
baff
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CN101851278A (zh
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杨莉
魏于全
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Sichuan University
CSPC Zhongqi Pharmaceutical Technology Shijiazhuang Co Ltd
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Sichuan University
CSPC Zhongqi Pharmaceutical Technology Shijiazhuang Co Ltd
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Publication of CN101851278A publication Critical patent/CN101851278A/zh
Priority to KR1020167020322A priority patent/KR101810551B1/ko
Priority to JP2013511528A priority patent/JP2013529900A/ja
Priority to PCT/CN2011/074687 priority patent/WO2011147320A1/zh
Priority to EP11786092.4A priority patent/EP2578603B1/en
Priority to KR1020127033484A priority patent/KR20130043642A/ko
Priority to US13/699,903 priority patent/US9290582B2/en
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CN2010101839059A 2010-05-26 2010-05-26 B细胞激活因子拮抗剂及其制备方法与用途 Active CN101851278B (zh)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CN2010101839059A CN101851278B (zh) 2010-05-26 2010-05-26 B细胞激活因子拮抗剂及其制备方法与用途
EP11786092.4A EP2578603B1 (en) 2010-05-26 2011-05-26 B cell activating factor antagonist and preparation method and use thereof
JP2013511528A JP2013529900A (ja) 2010-05-26 2011-05-26 B細胞活性化因子の拮抗物質、その調製方法及び利用法
PCT/CN2011/074687 WO2011147320A1 (zh) 2010-05-26 2011-05-26 B细胞激活因子拮抗剂及其制备方法与用途
KR1020167020322A KR101810551B1 (ko) 2010-05-26 2011-05-26 B세포 활성인자길항제 및 그의 제조방법과 용도
KR1020127033484A KR20130043642A (ko) 2010-05-26 2011-05-26 B세포활성인자길항제 및 그의 제조방법과 용도
US13/699,903 US9290582B2 (en) 2010-05-26 2011-05-26 B cell activating factor antagonist and preparation method and use thereof
JP2015151930A JP6320973B2 (ja) 2010-05-26 2015-07-31 B細胞活性化因子の拮抗物質、その調製方法及び利用法

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Application Number Priority Date Filing Date Title
CN2010101839059A CN101851278B (zh) 2010-05-26 2010-05-26 B细胞激活因子拮抗剂及其制备方法与用途

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CN101851278B true CN101851278B (zh) 2013-03-13

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US (1) US9290582B2 (enExample)
EP (1) EP2578603B1 (enExample)
JP (2) JP2013529900A (enExample)
KR (2) KR101810551B1 (enExample)
CN (1) CN101851278B (enExample)
WO (1) WO2011147320A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101851278B (zh) * 2010-05-26 2013-03-13 石药集团中奇制药技术(石家庄)有限公司 B细胞激活因子拮抗剂及其制备方法与用途
CN106220740A (zh) * 2016-08-18 2016-12-14 中山大学 可溶性蛋白baff在b细胞体外培养及扩增的应用
CN115812077A (zh) 2020-05-08 2023-03-17 高山免疫科学股份有限公司 April和baff抑制性免疫调节蛋白及其使用方法
WO2024197157A1 (en) 2023-03-21 2024-09-26 Biograph 55, Inc. Cd19/cd38 multispecific antibodies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1612750A (zh) * 2001-05-24 2005-05-04 津莫吉尼蒂克斯公司 Taci-免疫球蛋白融合蛋白质
CN1622995A (zh) * 2000-09-18 2005-06-01 比奥根公司 新的受体核酸及多肽
CN101678106A (zh) * 2007-03-27 2010-03-24 津莫吉尼蒂克斯公司 用于治疗自身免疫疾病的BLyS抑制和/或APRIL抑制与免疫抑制剂的组合

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Publication number Priority date Publication date Assignee Title
KR20040019105A (ko) 2001-08-03 2004-03-04 제넨테크, 인크. TACIs 및 BR3 폴리펩티드 및 이의 용도
EP2272868B1 (en) 2003-06-05 2015-03-04 Genentech, Inc. Combination therapy for B cell disorders
SI1631313T1 (sl) 2003-06-05 2015-06-30 Genentech, Inc. Kombinirana terapija za B-celične motnje
KR20070107687A (ko) 2004-12-31 2007-11-07 제넨테크, 인크. Br3과 결합하는 폴리펩티드, 및 그의 용도
JP2010501622A (ja) 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Fc−融合タンパク質の精製法
ES2595364T3 (es) * 2008-10-07 2016-12-29 The Regents Of The University Of California Producción de proteínas NELL recombinantes
CN101851278B (zh) * 2010-05-26 2013-03-13 石药集团中奇制药技术(石家庄)有限公司 B细胞激活因子拮抗剂及其制备方法与用途

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1622995A (zh) * 2000-09-18 2005-06-01 比奥根公司 新的受体核酸及多肽
CN1612750A (zh) * 2001-05-24 2005-05-04 津莫吉尼蒂克斯公司 Taci-免疫球蛋白融合蛋白质
CN101678106A (zh) * 2007-03-27 2010-03-24 津莫吉尼蒂克斯公司 用于治疗自身免疫疾病的BLyS抑制和/或APRIL抑制与免疫抑制剂的组合

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王燕等.人TACI-linker-BR3双受体融合基因真核表达载体构建及其在COS-7细胞中的表达.《第二军医大学学报》.2006,第27卷(第11期),1190-1195. *

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Publication number Publication date
EP2578603A1 (en) 2013-04-10
EP2578603A4 (en) 2014-03-26
KR20130043642A (ko) 2013-04-30
KR101810551B1 (ko) 2017-12-19
KR20160102066A (ko) 2016-08-26
CN101851278A (zh) 2010-10-06
JP2016019527A (ja) 2016-02-04
WO2011147320A1 (zh) 2011-12-01
US20130089549A1 (en) 2013-04-11
JP2013529900A (ja) 2013-07-25
JP6320973B2 (ja) 2018-05-09
EP2578603B1 (en) 2018-11-14
US9290582B2 (en) 2016-03-22

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