CN101810669A - Effervescent Chinese medicinal composition for curing flu and fever of livestock and preparation method thereof - Google Patents
Effervescent Chinese medicinal composition for curing flu and fever of livestock and preparation method thereof Download PDFInfo
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- CN101810669A CN101810669A CN200910228410A CN200910228410A CN101810669A CN 101810669 A CN101810669 A CN 101810669A CN 200910228410 A CN200910228410 A CN 200910228410A CN 200910228410 A CN200910228410 A CN 200910228410A CN 101810669 A CN101810669 A CN 101810669A
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Abstract
The invention relates to an effervescent Chinese medicinal composition for curing flu and fever of livestock and a preparation method thereof. The effervescent Chinese medicinal composition comprises the following components in percentage by weight: 10 to 40 percent of indigowoad root, 10 to 40 percent of virgate wormwood herb, 10 to 40 percent of licorice root, 10 to 30 percent of effervescing agent and 5 to 20 percent of lubricating agent. The effervescent Chinese medicinal composition has the advantages of scientific and reasonable formulation, rapid response, high bioavailability, no toxic or side effect, no medicament residue, low production cost and convenient use.
Description
Technical field
The invention belongs to domestic animal and use field of veterinary, especially a kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock and preparation method thereof.
Background technology
Flu and fever of livestock is one of common disease that arrives in the cattle breeding, gently then cause the domestic animal physical weakness, heavy then cause domestic animal death, though some medicines at the flu and fever of livestock symptom have been arranged on the market, but drug residue is insoluble problem always, and countries in the world require also more and more higher to edible safety, along with progress of science and technology, increasing drug residue is detected and confirms health harmful, countries in the world are all in the supervision that strengthens the residual problem of medicine, this has also produced no small impact to China's livestock and poultry breeding industry, and has proposed a urgent problem.Flu and fever of livestock, often with lethargy, loss of appetite or useless exhausted, carcass symptom such as become thin, and can cause tracheal bronchus, cardiorespiratory system disease, can cause death when serious.
Summary of the invention
The object of the present invention is to provide a kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, this effervescent Chinese medicinal composition set of dispense is than scientific and reasonable, and onset is rapid, and the bioavailability height has no side effect and drug residue, and production cost is lower, and is easy to use.
Another object of the present invention is to provide a kind of preparation method for the treatment of the effervescent Chinese medicinal composition of flu and fever of livestock.
The present invention is achieved by the following technical solutions:
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component of its effervescent Chinese medicinal composition and percentage by weight thereof are:
Radix Isatidis 10-40%;
Herba Artemisiae Scopariae 10-40%;
Radix Glycyrrhizae 10-40%;
Effervescent 10-30%;
Lubricant 5-20%.
And described effervescent is combined by weight 1: 1 by the wherein a kind of and sodium bicarbonate in tartaric acid, citric acid, the adipic acid.
And described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
A kind of preparation method for the treatment of the effervescent Chinese medicinal composition of flu and fever of livestock, the step of its preparation method is:
(1) according to weight proportion take by weighing Radix Isatidis pulverize, with the Radix Isatidis of 1/2 weight all by 80～100 mesh sieves, the Radix Isatidis of 1/2 weight decocts with water 3 times with the Herba Artemisiae Scopariae, the Radix Glycyrrhizae that take by weighing and pulverize according to weight proportion in addition, collecting decoction, filter, filtrate is condensed into thick paste, with sieve after the Radix Isatidis mix homogeneously, drying, pulverize and all by 80～100 mesh sieves the mixture A after obtaining handling;
(2) take by weighing effervescent, lubricant respectively according to weight proportion and pulverize, respectively all by 80～100 mesh sieves;
(3) with the abundant mix homogeneously of effervescent, lubricant after sieving in mixture A in the step (1) and the step (2), obtain mixture B;
(4) be binding agent system soft material with mixture B with concentration 50～60% alcoholic solution of 2～4%PVP, with soft material all by 10～15 mesh sieve system granules, under 50～60 ℃, carry out aeration-drying then, again all by 20～30 mesh sieve system granulate, promptly the obtain medical treatment effervescent Chinese medicinal composition of flu and fever of livestock of last tabletting.
Advantage of the present invention and beneficial effect are:
1, this effervescent Chinese medicinal composition Radix Isatidis, Herba Artemisiae Scopariae, Radix Glycyrrhizae have good heat-clearing and toxic substances removing as the natural Chinese medicine composition, the effect of dehumidifying function of gallbladder promoting.As the natural Chinese medicines extract, do not have any poisonous and harmful substance simultaneously, can not produce toxic and side effects, more can not exert an influence health to animal body.
2, this effervescent Chinese medicinal composition adopts the effervescent technology to introduce cleverly in the tablet of this medicine into, can make the dispensing treatment convenient and swift, save a large amount of manpower and materials, effective ingredient in the medicine is dissolved rapidly and uniformly, being convenient to poultry absorbs, improve bioavailability, can significantly improve the clinical efficacy of medicine.
3, combo distribution ratio of the present invention is scientific and reasonable, and onset is rapid, and the bioavailability height has no side effect and drug residue, and production cost is lower, and is easy to use.
The specific embodiment
The present invention is described in further detail by following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Radix Isatidis in the component of the present invention, Herba Artemisiae Scopariae, Radix Glycyrrhizae, tartaric acid, citric acid, adipic acid, sodium bicarbonate, sucralose, erythritol, magnesium stearate, dodecyl sodium sulfate all can be bought on market and obtain.
Embodiment 1
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component and the weight of its effervescent Chinese medicinal composition are respectively: Radix Isatidis 30Kg, Herba Artemisiae Scopariae 20Kg, Radix Glycyrrhizae 20Kg, effervescent 20Kg, lubricant 10Kg; Above-mentioned effervescent is made up of citric acid 10Kg and sodium bicarbonate 10Kg, and lubricant is a magnesium stearate.
A kind of preparation method for the treatment of the effervescent Chinese medicinal composition of flu and fever of livestock the steps include:
(1) according to weight proportion take by weighing Radix Isatidis pulverize, with the Radix Isatidis of 1/2 weight all by 80 mesh sieves, the Radix Isatidis of 1/2 weight decocts with water 3 times with the Herba Artemisiae Scopariae, the Radix Glycyrrhizae that take by weighing and pulverize according to weight proportion in addition, collecting decoction, filter, filtrate is condensed into thick paste, with sieve after the Radix Isatidis mix homogeneously, drying, pulverize and all by 80 mesh sieves the mixture A after obtaining handling;
(2) according to weight proportion take by weighing effervescent respectively, lubricant is pulverized, respectively all by 80～100 mesh sieves;
(3) with the abundant mix homogeneously of effervescent, lubricant after sieving in mixture A in the step (1) and the step (2), obtain mixture B;
(4) be binding agent system soft material with mixture B with 50% alcoholic solution of 2%PVP, with soft material all by 10 mesh sieve system granules, under 50 ℃, carry out aeration-drying then, more all by 20 mesh sieve system granulate, promptly the obtain medical treatment effervescent Chinese medicinal composition of flu and fever of livestock of last tabletting.
Embodiment 2
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component and the weight of its effervescent Chinese medicinal composition are respectively: Radix Isatidis 20Kg, Herba Artemisiae Scopariae 20Kg, Radix Glycyrrhizae 20Kg, effervescent 30Kg, lubricant 10Kg; Above-mentioned effervescent is made up of tartaric acid 15Kg and sodium bicarbonate 15Kg, and lubricant is an erythritol.
A kind of preparation method for the treatment of the effervescent Chinese medicinal composition of flu and fever of livestock, the step of its preparation method is:
(1) according to weight proportion take by weighing Radix Isatidis pulverize, with the Radix Isatidis of 1/2 weight all by 100 mesh sieves, the Radix Isatidis of 1/2 weight decocts with water 3 times with the Herba Artemisiae Scopariae, the Radix Glycyrrhizae that take by weighing and pulverize according to weight proportion in addition, collecting decoction, filter, filtrate is condensed into thick paste, with sieve after the Radix Isatidis mix homogeneously, drying, pulverize and all by 100 mesh sieves the mixture A after obtaining handling;
(2) take by weighing effervescent, lubricant pulverizing respectively according to weight proportion, respectively all by 100 mesh sieves;
(3) with the abundant mix homogeneously of effervescent, lubricant after sieving in mixture A in the step (1) and the step (2), obtain mixture B;
(4) be binding agent system soft material with mixture B with 60% alcoholic solution of 4%PVP, with soft material all by 15 mesh sieve system granules, under 60 ℃, carry out aeration-drying then, more all by 30 mesh sieve system granulate, promptly the obtain medical treatment effervescent Chinese medicinal composition of flu and fever of livestock of last tabletting.
Embodiment 3
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component and the weight of its effervescent Chinese medicinal composition are respectively: Radix Isatidis 20Kg, Herba Artemisiae Scopariae 30Kg, Radix Glycyrrhizae 29Kg, effervescent 16Kg, lubricant 5Kg; Above-mentioned effervescent is made up of adipic acid 8Kg and sodium bicarbonate 8Kg, and lubricant is a dodecyl sodium sulfate.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component and the weight of its effervescent Chinese medicinal composition are respectively: Radix Isatidis 20Kg, Herba Artemisiae Scopariae 10Kg, Radix Glycyrrhizae 39Kg, effervescent 26Kg, lubricant 5Kg; Above-mentioned effervescent is made up of citric acid 13Kg and sodium bicarbonate 13Kg, and lubricant is a magnesium stearate.
The step of its preparation method is with embodiment 1.
Embodiment 5
A kind of effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, the component and the weight of its effervescent Chinese medicinal composition are respectively: Radix Isatidis 40Kg, Herba Artemisiae Scopariae 20Kg, Radix Glycyrrhizae 20Kg, effervescent 10Kg, lubricant 10Kg; Above-mentioned effervescent is made up of citric acid 5Kg and sodium bicarbonate 5Kg, and lubricant is a magnesium stearate.
The step of its preparation method is with embodiment 1.
The present invention need not be dissolved in application in advance, directly drops into and cultures in the drinking water, and the per kilogram water body gets final product with this Chinese medicine composition 1 gram-10 grams.
The clinical practice experiment
1, experimental technique
Select 200 of the barren sows of not morbidity to be divided into two groups at random, one group is adopted common Radix Isatidis tablet to prevent, and one group is adopted the present invention to prevent; Selection has 200 of the barren sows of flu heating paresthesia to be divided into two groups at random, and one group is adopted common Radix Isatidis tablet to treat, and one group is adopted the present invention to treat.
2, experimental result
The morbidity rehabilitation situation of testing with pig through the primary part observation record obtains the result, and the experiment of prevention group all is effectively controlled with the pig incidence, and the state of an illness does not have further spreading trend; Treatment group therapeutic effect is obvious, adopts the experimental group cure rate 99% of novel isatis root effervescence tablet, improves 15% than the experimental group that adopts common Radix Isatidis tablet.
The characteristic of component among the present invention
1. Herba Artemisiae Scopariae: clearing away damp-heat, jaundice eliminating subcutaneous ulcer.Be used for jaundice oliguria, eczema pruritus, infectious jaundice type hepatitis.
2. Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
3. Radix Isatidis: maculae caused by violent heat pathogen; The hyperpyrexia headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Can prevent and treat epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis.
4. effervescent tablet is a kind of novel tablet of external in recent years Application and Development, the difference of it and conventional tablet, just be that it also contains gas-producing disintegrant, after effervescent tablet is put into water, under the effect of gas-producing disintegrant, produce a large amount of bubbles (carbon dioxide) at once, make rapid disintegrate of tablet and thawing, sometimes the bubble that disintegrate produces also can make tablet roll up and down in water, quickens its disintegrate and thawing.
Claims (4)
1. effervescent Chinese medicinal composition for the treatment of flu and fever of livestock, it is characterized in that: the component of this effervescent Chinese medicinal composition and percentage by weight thereof are:
Radix Isatidis 10-40%;
Herba Artemisiae Scopariae 10-40%;
Radix Glycyrrhizae 10-40%;
Effervescent 10-30%;
Lubricant 5-20%.
2. the effervescent Chinese medicinal composition of treatment flu and fever of livestock according to claim 1 is characterized in that: described effervescent is combined by weight 1: 1 by the wherein a kind of and sodium bicarbonate in tartaric acid, citric acid, the adipic acid.
3. the effervescent Chinese medicinal composition of treatment flu and fever of livestock according to claim 1 is characterized in that: described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
4. the preparation method of the effervescent Chinese medicinal composition of a treatment flu and fever of livestock as claimed in claim 1, it is characterized in that: the step of this preparation method is:
(1) according to weight proportion take by weighing Radix Isatidis pulverize, with the Radix Isatidis of 1/2 weight all by 80～100 mesh sieves, the Radix Isatidis of 1/2 weight decocts with water 3 times with the Herba Artemisiae Scopariae, the Radix Glycyrrhizae that take by weighing and pulverize according to weight proportion in addition, collecting decoction, filter, filtrate is condensed into thick paste, with sieve after the Radix Isatidis mix homogeneously, drying, pulverize and all by 80～100 mesh sieves the mixture A after obtaining handling;
(2) take by weighing effervescent, lubricant respectively according to weight proportion and pulverize, respectively all by 80～100 mesh sieves;
(3) with the abundant mix homogeneously of effervescent, lubricant after sieving in mixture A in the step (1) and the step (2), obtain mixture B;
(4) be binding agent system soft material with mixture B with concentration 50～60% alcoholic solution of 2～4%PVP, with soft material all by 10～15 mesh sieve system granules, under 50～60 ℃, carry out aeration-drying then, again all by 20～30 mesh sieve system granulate, promptly the obtain medical treatment effervescent Chinese medicinal composition of flu and fever of livestock of last tabletting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910228410A CN101810669A (en) | 2009-11-16 | 2009-11-16 | Effervescent Chinese medicinal composition for curing flu and fever of livestock and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910228410A CN101810669A (en) | 2009-11-16 | 2009-11-16 | Effervescent Chinese medicinal composition for curing flu and fever of livestock and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101810669A true CN101810669A (en) | 2010-08-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200910228410A Pending CN101810669A (en) | 2009-11-16 | 2009-11-16 | Effervescent Chinese medicinal composition for curing flu and fever of livestock and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109260290A (en) * | 2018-09-19 | 2019-01-25 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof improving sow production performance |
| CN114468162A (en) * | 2022-02-25 | 2022-05-13 | 四川恒通动物营养科技有限公司 | Additive for enhancing immunity and reproductive performance of sows and preparation method thereof |
-
2009
- 2009-11-16 CN CN200910228410A patent/CN101810669A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109260290A (en) * | 2018-09-19 | 2019-01-25 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof improving sow production performance |
| CN114468162A (en) * | 2022-02-25 | 2022-05-13 | 四川恒通动物营养科技有限公司 | Additive for enhancing immunity and reproductive performance of sows and preparation method thereof |
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Open date: 20100825 |