CN101802217B - 使用微粒和独特探针组筛选结合相互作用的方法 - Google Patents

使用微粒和独特探针组筛选结合相互作用的方法 Download PDF

Info

Publication number
CN101802217B
CN101802217B CN200880022471.5A CN200880022471A CN101802217B CN 101802217 B CN101802217 B CN 101802217B CN 200880022471 A CN200880022471 A CN 200880022471A CN 101802217 B CN101802217 B CN 101802217B
Authority
CN
China
Prior art keywords
microparticles
sso
dna
particles
hybridization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200880022471.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN101802217A (zh
Inventor
J·-H·李
T·农
T·陈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
One Lambda Inc
Original Assignee
One Lambda Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by One Lambda Inc filed Critical One Lambda Inc
Priority to CN201510411779.0A priority Critical patent/CN105112503B/zh
Publication of CN101802217A publication Critical patent/CN101802217A/zh
Application granted granted Critical
Publication of CN101802217B publication Critical patent/CN101802217B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN200880022471.5A 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法 Active CN101802217B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510411779.0A CN105112503B (zh) 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91592007P 2007-05-03 2007-05-03
US60/915,920 2007-05-03
PCT/US2008/062194 WO2008137530A1 (en) 2007-05-03 2008-05-01 Methods of screening for binding interaction using sets of microparticles and unique probes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510411779.0A Division CN105112503B (zh) 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法

Publications (2)

Publication Number Publication Date
CN101802217A CN101802217A (zh) 2010-08-11
CN101802217B true CN101802217B (zh) 2015-08-19

Family

ID=39943918

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880022471.5A Active CN101802217B (zh) 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法
CN201510411779.0A Active CN105112503B (zh) 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201510411779.0A Active CN105112503B (zh) 2007-05-03 2008-05-01 使用微粒和独特探针组筛选结合相互作用的方法

Country Status (8)

Country Link
US (2) US8748090B2 (enExample)
EP (1) EP2152908B1 (enExample)
JP (2) JP5684564B2 (enExample)
CN (2) CN101802217B (enExample)
AU (1) AU2008247686B2 (enExample)
BR (1) BRPI0810917A2 (enExample)
CA (1) CA2686211C (enExample)
WO (1) WO2008137530A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085548A2 (en) * 2009-01-22 2010-07-29 Li-Cor, Inc. Single molecule proteomics with dynamic probes
KR102759126B1 (ko) 2010-12-30 2025-01-24 파운데이션 메디신 인코포레이티드 종양 샘플의 다유전자 분석의 최적화
EP3569262A1 (en) 2013-03-14 2019-11-20 Tricol Biomedical, Inc. Biocompatible and bioabsorbable derivatized chitosan compositions
US10571468B2 (en) 2014-05-09 2020-02-25 One Lambda, Inc. Modified Fc gamma receptor type III (FCγIII, HNA-1) polypeptides and the uses thereof
EP3227464B1 (en) 2014-12-05 2022-04-20 Foundation Medicine, Inc. Multigene analysis of tumor samples
CN105158459A (zh) * 2015-07-10 2015-12-16 南京师范大学 一种水凝胶二氧化硅光子晶体微球化学发光法高灵敏度、低背景检测伏马毒素b1的方法
US20170082619A1 (en) * 2015-09-23 2017-03-23 One Lambda, Inc. Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens
WO2018140157A1 (en) * 2017-01-30 2018-08-02 Bio-Rad Laboratories, Inc. Measurements of protein-protein interactions at single molecule level
BR112020024727A2 (pt) 2018-06-11 2021-03-23 Foundation Medicine, Inc. composições e métodos para avaliação de alterações genômicas
US20210317528A1 (en) * 2018-07-23 2021-10-14 Genomics Usa, Inc. Blood typing using dna
IL285534B2 (en) * 2019-02-12 2025-04-01 Pact Pharma Inc Preparations and methods for identifying antigen-specific T cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514714B1 (en) * 1997-05-30 2003-02-04 One Lambda Method for immunobead flow cytometric detection of anti-HLA panel reactive antibody

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US6551784B2 (en) * 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
CA2032331A1 (en) * 1990-01-22 1991-07-23 Annie L. Wu Method and kits for detecting human leukocyte antigen dna
JPH0690757A (ja) * 1991-08-23 1994-04-05 Kitasato Inst:The Hla−drタイピング用塩基配列群とそれを用いた hla−drタイピング法
US6125194A (en) * 1996-02-06 2000-09-26 Caelum Research Corporation Method and system for re-screening nodules in radiological images using multi-resolution processing, neural network, and image processing
US6449562B1 (en) * 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US6207379B1 (en) 1998-09-11 2001-03-27 One Lambda Method for amplification of DNA
US7450229B2 (en) * 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US20030082549A1 (en) * 2000-08-30 2003-05-01 Xiangjun Liu Method for determining alleles
US20020155618A1 (en) * 2001-01-17 2002-10-24 O'hagan David Methods of analyzing and sorting one or more analytes
US20030165865A1 (en) 2001-01-29 2003-09-04 Hinkel Christopher A. Methods of analysis of nucleic acids
WO2002090337A1 (en) * 2001-05-07 2002-11-14 Smithkline Beecham Corporation Sulfonamides
CN101074450A (zh) 2001-09-24 2007-11-21 一兰姆达公司 诊断探针检测系统
US7732138B2 (en) * 2001-11-07 2010-06-08 Diagcor Bioscience Incorporation Limited Rapid genotyping analysis and the device thereof
US7848889B2 (en) * 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP4974899B2 (ja) * 2004-12-10 2012-07-11 ジェネラ バイオシステムズ リミテッド 組成物および検出方法
US7507588B2 (en) * 2005-04-20 2009-03-24 Becton, Dickinson And Company Multiplex microparticle system
US7871770B2 (en) 2005-08-09 2011-01-18 Maxwell Sensors, Inc. Light transmitted assay beads
US20070238140A1 (en) * 2006-04-07 2007-10-11 Pentoney Stephen L Jr Method For Multiplex Bead-Based Assays Using Chemiluminescence and Fluorescence

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514714B1 (en) * 1997-05-30 2003-02-04 One Lambda Method for immunobead flow cytometric detection of anti-HLA panel reactive antibody

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
F.Drago,et al..Genotyping of the Kidd blood group with allele-specific oligodeoxynucleotides coupled to fluorescent microspheres.《Transfusion Medicine》.2005,第15卷499-501. *

Also Published As

Publication number Publication date
JP5684564B2 (ja) 2015-03-11
JP2013116106A (ja) 2013-06-13
EP2152908A1 (en) 2010-02-17
CN101802217A (zh) 2010-08-11
CN105112503B (zh) 2018-10-16
BRPI0810917A2 (pt) 2014-10-29
US20140272976A1 (en) 2014-09-18
CN105112503A (zh) 2015-12-02
CA2686211A1 (en) 2008-11-13
JP5755632B2 (ja) 2015-07-29
US20090142762A1 (en) 2009-06-04
EP2152908A4 (en) 2010-07-28
JP2010526298A (ja) 2010-07-29
WO2008137530A1 (en) 2008-11-13
US8748090B2 (en) 2014-06-10
AU2008247686B2 (en) 2012-08-30
AU2008247686A1 (en) 2008-11-13
EP2152908B1 (en) 2017-03-15
CA2686211C (en) 2018-08-21
US9556483B2 (en) 2017-01-31

Similar Documents

Publication Publication Date Title
CN101802217B (zh) 使用微粒和独特探针组筛选结合相互作用的方法
Itoh et al. High-throughput DNA typing of HLA-A,-B,-C, and-DRB1 loci by a PCR–SSOP–Luminex method in the Japanese population
JP3093265B2 (ja) 遺伝子ファミリーのメンバーのヌクレオチドシーケンスを比較して遺伝子型を決定する方法とそのためのキット
US9562269B2 (en) Haplotying of HLA loci with ultra-deep shotgun sequencing
CA2640508C (en) Gene expression assays conducted by elemental analysis
US20050266432A1 (en) Haplotype markers for diagnosing susceptibility to immunological conditions
JP3384806B2 (ja) Hla−dr型別判定の実施を可能にするプローブ系および該プローブを用いる型別判定法
JP2009261358A (ja) Hla−drb1遺伝子を含むヒト遺伝子のアレル多型のタイピング方法及びこれに用いるキット
JP2004208586A (ja) Hlaの検出
US9133567B2 (en) Method for determining an attribute profile of biological samples
WO2008110206A1 (en) Method for determining a hla-dq haplotype in a subject
KR20070083924A (ko) 핵산 검출용 핵산 단편 및 핵산 검출방법
IL184724A (en) Oligonucleotide probe pair for the identification and typing of single nucleotide polymorphism of kidd blood group, methods employing it and kits comprising the same
KR101374247B1 (ko) 고해상도 mica 대립유전자 검출용 sprex―dna 칩 키트
EP2118316B1 (en) Use of oligonucleotide probes and method for the genomic typing of erythrocyte systems.
JP2006166911A (ja) 核酸検出用核酸断片および核酸検出方法
JP2010124823A (ja) 肥満遺伝子の遺伝子多型をタイピングするプライマーおよい競合プローブ
JP2005204558A (ja) 核酸検出用プローブおよび核酸検出方法
JPWO2000031295A1 (ja) Hlaクラスi対立遺伝子型の判別方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant