CN101747397B - 用于自动提取核酸的系统和方法 - Google Patents

用于自动提取核酸的系统和方法 Download PDF

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Publication number
CN101747397B
CN101747397B CN200910225856.8A CN200910225856A CN101747397B CN 101747397 B CN101747397 B CN 101747397B CN 200910225856 A CN200910225856 A CN 200910225856A CN 101747397 B CN101747397 B CN 101747397B
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CN
China
Prior art keywords
nucleic acid
sample
reagent
plate
cavity
Prior art date
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CN200910225856.8A
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English (en)
Chinese (zh)
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CN101747397A (zh
Inventor
H·-R·巴赫曼
K·巴梅特勒
H·伯克
J·博梅斯特
C·哈克
R·诺贝尔
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of CN101747397A publication Critical patent/CN101747397A/zh
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN200910225856.8A 2008-11-28 2009-11-30 用于自动提取核酸的系统和方法 Active CN101747397B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08170320.9 2008-11-28
EP08170320.9A EP2192186B1 (en) 2008-11-28 2008-11-28 System and method for the automated extraction of nucleic acids

Publications (2)

Publication Number Publication Date
CN101747397A CN101747397A (zh) 2010-06-23
CN101747397B true CN101747397B (zh) 2015-02-11

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200910225856.8A Active CN101747397B (zh) 2008-11-28 2009-11-30 用于自动提取核酸的系统和方法

Country Status (6)

Country Link
US (1) US20100137574A1 (enExample)
EP (1) EP2192186B1 (enExample)
JP (1) JP5268870B2 (enExample)
CN (1) CN101747397B (enExample)
CA (1) CA2686597C (enExample)
ES (1) ES2567067T3 (enExample)

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JP5846773B2 (ja) 2010-06-29 2016-01-20 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ サンプルの分配
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2703820B1 (en) * 2012-08-31 2019-08-28 F. Hoffmann-La Roche AG Mobile tip waste rack
TWI477755B (zh) * 2013-06-04 2015-03-21 Genereach Biotechnology Corp 核酸萃取設備
CN103789198B (zh) * 2014-02-27 2015-09-16 苏州天隆生物科技有限公司 全自动核酸提取仪
ES2854880T3 (es) * 2014-06-11 2021-09-23 Hoffmann La Roche Procedimiento y sistema para el análisis de diagnóstico in vitro
CN105940305B (zh) * 2014-06-17 2019-08-27 深圳迈瑞生物医疗电子股份有限公司 提取物分离装置及其工作方法
KR102363674B1 (ko) * 2015-04-06 2022-02-15 메소 스케일 테크놀러지즈, 엘엘시 소모성 진탕 장치를 포함하는, 전기화학발광을 이용하여 검정법을 수행하기 위한 고처리율 시스템
CN106701527A (zh) * 2015-08-11 2017-05-24 广州康昕瑞基因健康科技有限公司 一种试剂工作站
CN105223054B (zh) * 2015-10-13 2019-06-11 毛坤云 生物检材载体批量快速去除装置及去除方法
JP6771903B2 (ja) * 2016-02-29 2020-10-21 シスメックス株式会社 検体前処理装置、検体前処理カートリッジおよび検体前処理方法
CN109982778A (zh) * 2016-09-23 2019-07-05 阿谢尔德克斯有限公司 流体系统及相关方法
US20200363299A1 (en) * 2016-11-23 2020-11-19 Hangzhou Gene-Meta Medical Device Co., Ltd. Apparatus for automating pretreatment of nucleic acid detection
CN106754349A (zh) * 2017-01-13 2017-05-31 广东顺德工业设计研究院(广东顺德创新设计研究院) 加热振动装置及包括该加热振动装置的核酸提取设备
CN107557356B (zh) * 2017-09-05 2023-06-09 南京万承生物科技有限公司 一种小型多通道文库构建仪及构建文库的方法
SG11202002507UA (en) * 2018-03-02 2020-04-29 Psomagen Inc Method and system for high-throughput particle handling by use of magnetic fields and device
WO2019182903A1 (en) * 2018-03-20 2019-09-26 Nugen Technologies, Inc. Methods for linear sample processing
CN108949553B (zh) * 2018-08-23 2024-04-30 苏州英芮诚生化科技有限公司 一种核酸提取仪用弃废液装置
US20210403846A1 (en) * 2018-11-16 2021-12-30 Aixinno Limited Lab-ware and handling system to handle lab-ware in a cell culture process
CN110208063A (zh) * 2019-06-27 2019-09-06 中国农业科学院农业质量标准与检测技术研究所 一种在线自动化磁性纳米材料震荡-解吸装置
CN112226354A (zh) * 2020-09-10 2021-01-15 襄阳市远杰精密机械有限公司 一种多样本通用型全自动核酸提取仪
CN112920948A (zh) * 2021-03-31 2021-06-08 苏州博捷特生物科技有限公司 一种核酸检测前处理仪
EP4349953A4 (en) * 2021-05-31 2025-06-04 Universal Bio Research Co., Ltd. SAMPLE TREATMENT DEVICE
CN113308364A (zh) * 2021-06-09 2021-08-27 北京京东方技术开发有限公司 核酸提取基板、核酸提取设备和核酸提取方法
CN113583812B (zh) * 2021-08-04 2023-11-28 上海思路迪生物医学科技有限公司 一种适用于模块化工作站的核酸提取系统及方法
CN118922523A (zh) * 2022-09-30 2024-11-08 深圳华大生命科学研究院 生物芯片的自动化控制系统及其自动化控制方法
CN117247834B (zh) * 2023-11-17 2024-01-30 北京万泰生物药业股份有限公司 高通量全自动核酸检测仪器及方法

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US20030059823A1 (en) * 2001-09-21 2003-03-27 Juki Corporation Hybridization apparatus and method for detecting nucleic acid in sample using the same
CN1558951A (zh) * 2001-09-28 2004-12-29 株式会社益力多本社 核酸提取装置

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EP0977039A2 (en) * 1998-07-27 2000-02-02 Hitachi, Ltd. Handling method of body fluid sample and analysis apparatus using the same
US20030059823A1 (en) * 2001-09-21 2003-03-27 Juki Corporation Hybridization apparatus and method for detecting nucleic acid in sample using the same
CN1558951A (zh) * 2001-09-28 2004-12-29 株式会社益力多本社 核酸提取装置

Also Published As

Publication number Publication date
CA2686597A1 (en) 2010-05-28
JP2010127941A (ja) 2010-06-10
ES2567067T3 (es) 2016-04-19
EP2192186A1 (en) 2010-06-02
CN101747397A (zh) 2010-06-23
CA2686597C (en) 2016-10-11
JP5268870B2 (ja) 2013-08-21
US20100137574A1 (en) 2010-06-03
EP2192186B1 (en) 2016-03-09

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