CN101678046A - 稳定化的吡铂口服剂型 - Google Patents

稳定化的吡铂口服剂型 Download PDF

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Publication number
CN101678046A
CN101678046A CN200880011357A CN200880011357A CN101678046A CN 101678046 A CN101678046 A CN 101678046A CN 200880011357 A CN200880011357 A CN 200880011357A CN 200880011357 A CN200880011357 A CN 200880011357A CN 101678046 A CN101678046 A CN 101678046A
Authority
CN
China
Prior art keywords
picoplatin
dosage form
oral dosage
core
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880011357A
Other languages
English (en)
Chinese (zh)
Inventor
A·J·利
C·A·普罗西夏伊
E·S·Y·王
C·M·吉安多米尼科
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Poniard Pharmaceuticals Inc
Original Assignee
Genzyme Corp
Poniard Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Poniard Pharmaceuticals Inc filed Critical Genzyme Corp
Publication of CN101678046A publication Critical patent/CN101678046A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200880011357A 2007-02-09 2008-02-08 稳定化的吡铂口服剂型 Pending CN101678046A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US88917107P 2007-02-09 2007-02-09
US60/889,171 2007-02-09
US88968107P 2007-02-13 2007-02-13
US60/889,681 2007-02-13
PCT/US2008/001752 WO2008097661A1 (en) 2007-02-09 2008-02-08 Stabilized picoplatin oral dosage form

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201410283507.2A Division CN104288119A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Publications (1)

Publication Number Publication Date
CN101678046A true CN101678046A (zh) 2010-03-24

Family

ID=39682046

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880011357A Pending CN101678046A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型
CN201410283507.2A Pending CN104288119A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201410283507.2A Pending CN104288119A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Country Status (12)

Country Link
EP (1) EP2114418A4 (enExample)
JP (1) JP2010518089A (enExample)
KR (1) KR20090109129A (enExample)
CN (2) CN101678046A (enExample)
AU (1) AU2008214202A1 (enExample)
BR (1) BRPI0806418A2 (enExample)
CA (1) CA2677640A1 (enExample)
HK (1) HK1206267A1 (enExample)
IL (1) IL200262A0 (enExample)
MX (1) MX2009008488A (enExample)
RU (1) RU2009133446A (enExample)
WO (1) WO2008097661A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108864177A (zh) * 2018-04-20 2018-11-23 公安部物证鉴定中心 [2h3]-1-甲氨基-2-苯基丙烷的合成方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178564B2 (en) 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20120148661A1 (en) * 2009-04-15 2012-06-14 Poniard Pharmaceuticals, Inc. High bioavailability oral picoplatin anti-cancer therapy
JP2017516853A (ja) * 2014-05-23 2017-06-22 ミングサイト ファーマシューティカルズ，インク． 自己免疫性疾患の処置
CN107778331B (zh) * 2016-08-27 2020-06-30 鲁南制药集团股份有限公司 一种甲啶铂的提纯方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
CA2395711A1 (en) * 2000-02-16 2002-07-18 Yamanouchi Pharmaceutical Co., Ltd. Pharmaceutical compositions
CA2445734A1 (en) * 2001-04-23 2002-10-31 Nucryst Pharmaceuticals Corp. Medicament containing a metal such as silver, gold, platinum or palladium as an antimicrobial agent and their use to induce apoptosis in cancerous tissue
DE10141528B4 (de) * 2001-08-24 2006-08-10 Faustus Forschungs Cie. Translational Cancer Research Gmbh Platin(II)- und Platin(IV)-Komplexe und ihre Verwendung
US7691833B2 (en) * 2002-03-01 2010-04-06 Trustees Of Dartmouth College Compositions and methods for preventing sporadic neoplasia in colon
AU2003251955A1 (en) * 2002-07-16 2004-02-02 Sonus Pharmaceuticals, Inc. Platinum compound
MXPA05001312A (es) * 2002-08-02 2005-08-03 Transave Inc Agregados de platino y proceso para producir los mismos.
AU2005223654A1 (en) * 2004-03-18 2005-09-29 Transave, Inc. Administration of cisplatin by inhalation
US20060205810A1 (en) * 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108864177A (zh) * 2018-04-20 2018-11-23 公安部物证鉴定中心 [2h3]-1-甲氨基-2-苯基丙烷的合成方法
CN108864177B (zh) * 2018-04-20 2020-07-28 公安部物证鉴定中心 [2h3]-1-甲氨基-2-苯基丙烷的合成方法

Also Published As

Publication number Publication date
CN104288119A (zh) 2015-01-21
MX2009008488A (es) 2010-01-15
BRPI0806418A2 (pt) 2011-09-06
CA2677640A1 (en) 2008-08-14
HK1206267A1 (en) 2016-01-08
EP2114418A4 (en) 2013-01-09
JP2010518089A (ja) 2010-05-27
AU2008214202A1 (en) 2008-08-14
KR20090109129A (ko) 2009-10-19
IL200262A0 (en) 2010-04-29
WO2008097661A1 (en) 2008-08-14
EP2114418A1 (en) 2009-11-11
RU2009133446A (ru) 2011-03-20

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