CN101677984A - 地来西坦在治疗慢性疼痛中的应用 - Google Patents

地来西坦在治疗慢性疼痛中的应用 Download PDF

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Publication number
CN101677984A
CN101677984A CN200880015837A CN200880015837A CN101677984A CN 101677984 A CN101677984 A CN 101677984A CN 200880015837 A CN200880015837 A CN 200880015837A CN 200880015837 A CN200880015837 A CN 200880015837A CN 101677984 A CN101677984 A CN 101677984A
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CN
China
Prior art keywords
deleracetam
treatment
pain
administration
chronic pain
Prior art date
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Pending
Application number
CN200880015837A
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English (en)
Chinese (zh)
Inventor
C·法里纳
C·格拉蒂尼
P·佩特利罗
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Neurotune AG
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Neurotune AG
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Filing date
Publication date
Application filed by Neurotune AG filed Critical Neurotune AG
Publication of CN101677984A publication Critical patent/CN101677984A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880015837A 2007-04-16 2008-04-15 地来西坦在治疗慢性疼痛中的应用 Pending CN101677984A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000770A ITMI20070770A1 (it) 2007-04-16 2007-04-16 Impiego di dimiracetam nel trattamento del dolore cronico
ITMI2007A000770 2007-04-16
PCT/EP2008/054553 WO2008125674A1 (en) 2007-04-16 2008-04-15 Use of dimiracetam in the treatment of chronic pain

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201310182360.3A Division CN103284997B (zh) 2007-04-16 2008-04-15 地来西坦在治疗慢性疼痛中的应用

Publications (1)

Publication Number Publication Date
CN101677984A true CN101677984A (zh) 2010-03-24

Family

ID=39628738

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880015837A Pending CN101677984A (zh) 2007-04-16 2008-04-15 地来西坦在治疗慢性疼痛中的应用
CN201310182360.3A Expired - Fee Related CN103284997B (zh) 2007-04-16 2008-04-15 地来西坦在治疗慢性疼痛中的应用

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201310182360.3A Expired - Fee Related CN103284997B (zh) 2007-04-16 2008-04-15 地来西坦在治疗慢性疼痛中的应用

Country Status (15)

Country Link
US (2) US7989421B2 (enExample)
EP (3) EP2620149A3 (enExample)
JP (1) JP5409602B2 (enExample)
CN (2) CN101677984A (enExample)
AU (1) AU2008237901B2 (enExample)
BR (1) BRPI0810475A2 (enExample)
CA (1) CA2684363C (enExample)
EA (2) EA022867B1 (enExample)
ES (2) ES2536631T3 (enExample)
IL (2) IL201498A (enExample)
IT (1) ITMI20070770A1 (enExample)
MX (1) MX2009011380A (enExample)
PL (2) PL2146706T3 (enExample)
WO (1) WO2008125674A1 (enExample)
ZA (1) ZA200906991B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102743372A (zh) * 2012-06-30 2012-10-24 江苏省中医药研究院 一种化疗致血痹动物模型建立方法
CN103052638A (zh) * 2010-07-26 2013-04-17 神经协调股份公司 制备地来西坦的方法
CN110719779A (zh) * 2017-05-31 2020-01-21 美蒂斯制药公司 包含非外消旋比例的(r)-地来西坦(1)和(s)-地来西坦(2)的协同组合物
CN111356454A (zh) * 2017-11-21 2020-06-30 湖南湘源美东医药科技有限公司 含有双环铂的组合产品、其制备方法及其用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125898B2 (en) 2008-11-14 2015-09-08 Neurotune Ag Acetam derivatives for pain relief
EP2658540A1 (en) * 2010-10-29 2013-11-06 Neurotune AG Therapeutic use of dimiracetam to prevent the hand&foot syndrome caused by sorafenib
JPWO2012137645A1 (ja) * 2011-04-07 2014-07-28 旭化成ファーマ株式会社 抗癌剤に起因する異痛症の予防及び／又は治療剤
DE102019107619A1 (de) 2019-03-25 2020-10-01 Mondi Ag Verpackungsbeutel aus einem Kunststoffgewebeverbund
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3324219A1 (de) * 1983-07-05 1985-01-17 Hoechst Ag, 6230 Frankfurt Mehrlagige elektroisolierfolie
US5028595A (en) * 1987-09-18 1991-07-02 Hoffmann-La Roche Inc. Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
IT1233860B (it) 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
GB9123641D0 (en) 1991-11-07 1992-01-02 Isf Spa Process
ES2287039T3 (es) * 1999-12-01 2007-12-16 Ucb, S.A. Un derivado de pirrolidinacetamida para el tratamiento de dolor cronico o neuropatico.
JPWO2002053153A1 (ja) * 2000-12-28 2004-04-30 第一製薬株式会社 神経因性疼痛治療及び予防薬
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103052638A (zh) * 2010-07-26 2013-04-17 神经协调股份公司 制备地来西坦的方法
CN102743372A (zh) * 2012-06-30 2012-10-24 江苏省中医药研究院 一种化疗致血痹动物模型建立方法
CN102743372B (zh) * 2012-06-30 2015-09-09 江苏省中医药研究院 一种化疗致血痹动物模型建立方法
CN110719779A (zh) * 2017-05-31 2020-01-21 美蒂斯制药公司 包含非外消旋比例的(r)-地来西坦(1)和(s)-地来西坦(2)的协同组合物
CN110719779B (zh) * 2017-05-31 2022-02-01 美蒂斯制药公司 包含非外消旋比例的(r)-地来西坦(1)和(s)-地来西坦(2)的协同组合物
CN111356454A (zh) * 2017-11-21 2020-06-30 湖南湘源美东医药科技有限公司 含有双环铂的组合产品、其制备方法及其用途
CN111356454B (zh) * 2017-11-21 2023-04-07 湖南湘源美东医药科技有限公司 含有双环铂的组合产品、其制备方法及其用途

Also Published As

Publication number Publication date
JP5409602B2 (ja) 2014-02-05
EA201300826A1 (ru) 2013-11-29
US20100129469A1 (en) 2010-05-27
EP2146706B1 (en) 2015-02-25
CN103284997A (zh) 2013-09-11
EP2146706A1 (en) 2010-01-27
PL2146706T3 (pl) 2015-07-31
ZA200906991B (en) 2011-03-30
IL201498A (en) 2013-10-31
US20110251250A1 (en) 2011-10-13
EP2620149A3 (en) 2013-08-07
BRPI0810475A2 (pt) 2015-10-20
EA200901237A1 (ru) 2010-04-30
HK1209053A1 (en) 2016-03-24
AU2008237901A1 (en) 2008-10-23
MX2009011380A (es) 2010-07-06
ES2536631T3 (es) 2015-05-27
CA2684363A1 (en) 2008-10-23
EA022867B1 (ru) 2016-03-31
IL218851A0 (en) 2012-05-31
CA2684363C (en) 2016-02-09
WO2008125674A1 (en) 2008-10-23
US7989421B2 (en) 2011-08-02
IL218851A (en) 2013-09-30
EP2857017B1 (en) 2016-05-25
AU2008237901B2 (en) 2013-06-27
JP2010524882A (ja) 2010-07-22
IL201498A0 (en) 2010-05-31
EP2857017A2 (en) 2015-04-08
EA019354B1 (ru) 2014-03-31
EP2620149A2 (en) 2013-07-31
CN103284997B (zh) 2015-06-03
EP2857017A3 (en) 2015-05-06
ITMI20070770A1 (it) 2008-10-17
US8222241B2 (en) 2012-07-17
PL2857017T3 (pl) 2016-11-30
ES2584161T3 (es) 2016-09-26

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