CA2684363C - Use of dimiracetam in the treatment of chronic pain - Google Patents

Use of dimiracetam in the treatment of chronic pain Download PDF

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Publication number
CA2684363C
CA2684363C CA2684363A CA2684363A CA2684363C CA 2684363 C CA2684363 C CA 2684363C CA 2684363 A CA2684363 A CA 2684363A CA 2684363 A CA2684363 A CA 2684363A CA 2684363 C CA2684363 C CA 2684363C
Authority
CA
Canada
Prior art keywords
dimiracetam
dosage unit
amount
pharmaceutical composition
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2684363A
Other languages
English (en)
French (fr)
Other versions
CA2684363A1 (en
Inventor
Carlo Farina
Carla Ghelardini
Paola Petrillo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurotune AG
Original Assignee
Neurotune AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurotune AG filed Critical Neurotune AG
Publication of CA2684363A1 publication Critical patent/CA2684363A1/en
Application granted granted Critical
Publication of CA2684363C publication Critical patent/CA2684363C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2684363A 2007-04-16 2008-04-15 Use of dimiracetam in the treatment of chronic pain Expired - Fee Related CA2684363C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000770A ITMI20070770A1 (it) 2007-04-16 2007-04-16 Impiego di dimiracetam nel trattamento del dolore cronico
ITMI2007A000770 2007-04-16
PCT/EP2008/054553 WO2008125674A1 (en) 2007-04-16 2008-04-15 Use of dimiracetam in the treatment of chronic pain

Publications (2)

Publication Number Publication Date
CA2684363A1 CA2684363A1 (en) 2008-10-23
CA2684363C true CA2684363C (en) 2016-02-09

Family

ID=39628738

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2684363A Expired - Fee Related CA2684363C (en) 2007-04-16 2008-04-15 Use of dimiracetam in the treatment of chronic pain

Country Status (15)

Country Link
US (2) US7989421B2 (enExample)
EP (3) EP2146706B1 (enExample)
JP (1) JP5409602B2 (enExample)
CN (2) CN103284997B (enExample)
AU (1) AU2008237901B2 (enExample)
BR (1) BRPI0810475A2 (enExample)
CA (1) CA2684363C (enExample)
EA (2) EA019354B1 (enExample)
ES (2) ES2584161T3 (enExample)
IL (2) IL201498A (enExample)
IT (1) ITMI20070770A1 (enExample)
MX (1) MX2009011380A (enExample)
PL (2) PL2857017T3 (enExample)
WO (1) WO2008125674A1 (enExample)
ZA (1) ZA200906991B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125898B2 (en) 2008-11-14 2015-09-08 Neurotune Ag Acetam derivatives for pain relief
PT2598504E (pt) * 2010-07-26 2014-07-14 Neurotune Ag Novo processo de fabrico de dimiracetam
US20140051730A1 (en) * 2010-10-29 2014-02-20 Neurotune Ag Therapeutic use of dimiracetam to prevent the hand and foot syndrome caused by sorafenib
JPWO2012137645A1 (ja) * 2011-04-07 2014-07-28 旭化成ファーマ株式会社 抗癌剤に起因する異痛症の予防及び/又は治療剤
CN102743372B (zh) * 2012-06-30 2015-09-09 江苏省中医药研究院 一种化疗致血痹动物模型建立方法
JOP20190251A1 (ar) * 2017-05-31 2019-10-21 Metys Pharmaceuticals AG تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية
CN111356454B (zh) * 2017-11-21 2023-04-07 湖南湘源美东医药科技有限公司 含有双环铂的组合产品、其制备方法及其用途
DE102019107619A1 (de) 2019-03-25 2020-10-01 Mondi Ag Verpackungsbeutel aus einem Kunststoffgewebeverbund
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3324219A1 (de) * 1983-07-05 1985-01-17 Hoechst Ag, 6230 Frankfurt Mehrlagige elektroisolierfolie
US5028595A (en) * 1987-09-18 1991-07-02 Hoffmann-La Roche Inc. Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
IT1233860B (it) 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
GB9123641D0 (en) 1991-11-07 1992-01-02 Isf Spa Process
TWI238062B (en) * 1999-12-01 2005-08-21 Ucb Sa A pyrrolidineacetamide derivative alone or in combination for treatment of CNS disorders
EP1356812B1 (en) 2000-12-28 2009-05-13 Hamilton Pharmaceuticals, Inc. Medicines for treatment and prevention of neurogenic pain
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,

Also Published As

Publication number Publication date
EP2857017B1 (en) 2016-05-25
ITMI20070770A1 (it) 2008-10-17
HK1209053A1 (en) 2016-03-24
ES2536631T3 (es) 2015-05-27
IL201498A0 (en) 2010-05-31
JP2010524882A (ja) 2010-07-22
ES2584161T3 (es) 2016-09-26
EP2146706B1 (en) 2015-02-25
EP2857017A2 (en) 2015-04-08
ZA200906991B (en) 2011-03-30
JP5409602B2 (ja) 2014-02-05
IL218851A0 (en) 2012-05-31
WO2008125674A1 (en) 2008-10-23
EA022867B1 (ru) 2016-03-31
AU2008237901B2 (en) 2013-06-27
PL2857017T3 (pl) 2016-11-30
US20100129469A1 (en) 2010-05-27
IL218851A (en) 2013-09-30
EA019354B1 (ru) 2014-03-31
AU2008237901A1 (en) 2008-10-23
US8222241B2 (en) 2012-07-17
CN103284997B (zh) 2015-06-03
EP2620149A3 (en) 2013-08-07
EP2146706A1 (en) 2010-01-27
CA2684363A1 (en) 2008-10-23
IL201498A (en) 2013-10-31
EP2620149A2 (en) 2013-07-31
CN101677984A (zh) 2010-03-24
US20110251250A1 (en) 2011-10-13
EA200901237A1 (ru) 2010-04-30
US7989421B2 (en) 2011-08-02
EP2857017A3 (en) 2015-05-06
CN103284997A (zh) 2013-09-11
BRPI0810475A2 (pt) 2015-10-20
PL2146706T3 (pl) 2015-07-31
MX2009011380A (es) 2010-07-06
EA201300826A1 (ru) 2013-11-29

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Effective date: 20130409

MKLA Lapsed

Effective date: 20220419