CN101642449A - Skin mucous membrane disinfectants and preparation method thereof - Google Patents
Skin mucous membrane disinfectants and preparation method thereof Download PDFInfo
- Publication number
- CN101642449A CN101642449A CN200910164371A CN200910164371A CN101642449A CN 101642449 A CN101642449 A CN 101642449A CN 200910164371 A CN200910164371 A CN 200910164371A CN 200910164371 A CN200910164371 A CN 200910164371A CN 101642449 A CN101642449 A CN 101642449A
- Authority
- CN
- China
- Prior art keywords
- dimethyl ammonium
- decyl
- ionized water
- solution
- mucous membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000645 desinfectant Substances 0.000 title claims abstract description 57
- 210000004400 mucous membrane Anatomy 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 54
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 31
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 29
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 29
- 229960002233 benzalkonium bromide Drugs 0.000 claims abstract description 29
- KHSLHYAUZSPBIU-UHFFFAOYSA-M benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 claims abstract description 29
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 18
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 18
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 18
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims abstract description 17
- 229920000053 polysorbate 80 Polymers 0.000 claims abstract description 17
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims abstract description 3
- -1 decyl alkyl dimethyl ammonium chlorides Chemical class 0.000 claims description 60
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 51
- SRESKMPUIWAGML-UHFFFAOYSA-N n,n-dimethyldecan-1-amine;hydrobromide Chemical compound Br.CCCCCCCCCCN(C)C SRESKMPUIWAGML-UHFFFAOYSA-N 0.000 claims description 37
- 125000001453 quaternary ammonium group Chemical class 0.000 claims description 36
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Natural products C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 claims description 28
- 238000003756 stirring Methods 0.000 claims description 26
- 230000001954 sterilising effect Effects 0.000 claims description 10
- 230000000694 effects Effects 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 5
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 5
- IQDGSYLLQPDQDV-UHFFFAOYSA-N dimethylazanium;chloride Chemical compound Cl.CNC IQDGSYLLQPDQDV-UHFFFAOYSA-N 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 241000222122 Candida albicans Species 0.000 abstract description 3
- 241000191967 Staphylococcus aureus Species 0.000 abstract description 3
- 229940095731 candida albicans Drugs 0.000 abstract description 3
- 230000002147 killing effect Effects 0.000 abstract description 3
- 210000004877 mucosa Anatomy 0.000 abstract description 3
- 150000001875 compounds Chemical class 0.000 abstract description 2
- 229920003023 plastic Polymers 0.000 abstract description 2
- 239000004033 plastic Substances 0.000 abstract description 2
- 235000011187 glycerol Nutrition 0.000 abstract 2
- 239000004615 ingredient Substances 0.000 abstract 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 1
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000009360 aquaculture Methods 0.000 abstract 1
- 244000144974 aquaculture Species 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002070 germicidal effect Effects 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960003500 triclosan Drugs 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 241000725303 Human immunodeficiency virus Species 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 241000195493 Cryptophyta Species 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000002798 bone marrow cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000017 mucous membrane irritation Toxicity 0.000 description 1
- 231100000286 mucous membrane, eye irritation or corrosion testing Toxicity 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101643712A CN101642449B (en) | 2009-09-08 | 2009-09-08 | Skin mucous membrane disinfectants and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101643712A CN101642449B (en) | 2009-09-08 | 2009-09-08 | Skin mucous membrane disinfectants and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101642449A true CN101642449A (en) | 2010-02-10 |
CN101642449B CN101642449B (en) | 2012-06-27 |
Family
ID=41654609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009101643712A Active CN101642449B (en) | 2009-09-08 | 2009-09-08 | Skin mucous membrane disinfectants and preparation method thereof |
Country Status (1)
Country | Link |
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CN (1) | CN101642449B (en) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102119840A (en) * | 2011-03-10 | 2011-07-13 | 胡万宁 | Hospital infection preventing disposable hand cleaning disinfecting towel for medical personnel and use thereof |
CN102335161A (en) * | 2011-07-15 | 2012-02-01 | 成都顺发消洗科技有限公司 | Spermicide for disinfecting skin and mucous membrane, preparation method thereof |
CN104127396A (en) * | 2014-08-07 | 2014-11-05 | 张晓东 | Antibacterial drug as well as preparation method and application thereof |
CN104757019A (en) * | 2015-03-23 | 2015-07-08 | 苏州谷力生物科技有限公司 | Composite sanitizer and preparation method thereof |
CN105125536A (en) * | 2015-07-29 | 2015-12-09 | 江南大学 | Composition for treating dermatoses caused by bacteria, fungi, viruses or parasites |
CN104127396B (en) * | 2014-08-07 | 2016-11-30 | 张晓东 | A kind of antibacterials and its preparation method and application |
CN106420683A (en) * | 2016-08-30 | 2017-02-22 | 郑州嘉泰生物科技有限公司 | Highly-efficient antibacterial liquid used for skin mucous membrane |
CN106511427A (en) * | 2016-12-27 | 2017-03-22 | 四川默森药业有限公司 | Composition for skin mucous membrane disinfection and preparation method of composition |
CN109316536A (en) * | 2018-10-22 | 2019-02-12 | 湖南中威制药有限公司 | A kind of skin mucosa disinfecting agent and preparation method thereof |
CN111637566A (en) * | 2020-07-17 | 2020-09-08 | 汤峰 | Medical grade air purification device |
CN111811075A (en) * | 2020-07-17 | 2020-10-23 | 姹ゅ嘲 | Application of skin mucosa disinfectant with virus inactivation effect in air purification |
CN112244043A (en) * | 2020-09-15 | 2021-01-22 | 江苏瑞丰科技实业有限公司 | Air disinfection and refreshing spray |
WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
-
2009
- 2009-09-08 CN CN2009101643712A patent/CN101642449B/en active Active
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102119840A (en) * | 2011-03-10 | 2011-07-13 | 胡万宁 | Hospital infection preventing disposable hand cleaning disinfecting towel for medical personnel and use thereof |
CN102335161A (en) * | 2011-07-15 | 2012-02-01 | 成都顺发消洗科技有限公司 | Spermicide for disinfecting skin and mucous membrane, preparation method thereof |
CN104127396A (en) * | 2014-08-07 | 2014-11-05 | 张晓东 | Antibacterial drug as well as preparation method and application thereof |
CN104127396B (en) * | 2014-08-07 | 2016-11-30 | 张晓东 | A kind of antibacterials and its preparation method and application |
CN104757019A (en) * | 2015-03-23 | 2015-07-08 | 苏州谷力生物科技有限公司 | Composite sanitizer and preparation method thereof |
CN105125536B (en) * | 2015-07-29 | 2018-05-04 | 无锡宏瑞生物医药科技有限公司 | Treat bacterium, fungi, virus or dermopathic composition caused by parasite |
CN105125536A (en) * | 2015-07-29 | 2015-12-09 | 江南大学 | Composition for treating dermatoses caused by bacteria, fungi, viruses or parasites |
CN106420683A (en) * | 2016-08-30 | 2017-02-22 | 郑州嘉泰生物科技有限公司 | Highly-efficient antibacterial liquid used for skin mucous membrane |
CN106511427A (en) * | 2016-12-27 | 2017-03-22 | 四川默森药业有限公司 | Composition for skin mucous membrane disinfection and preparation method of composition |
CN109316536A (en) * | 2018-10-22 | 2019-02-12 | 湖南中威制药有限公司 | A kind of skin mucosa disinfecting agent and preparation method thereof |
WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
CN111637566A (en) * | 2020-07-17 | 2020-09-08 | 汤峰 | Medical grade air purification device |
CN111811075A (en) * | 2020-07-17 | 2020-10-23 | 姹ゅ嘲 | Application of skin mucosa disinfectant with virus inactivation effect in air purification |
CN112244043A (en) * | 2020-09-15 | 2021-01-22 | 江苏瑞丰科技实业有限公司 | Air disinfection and refreshing spray |
Also Published As
Publication number | Publication date |
---|---|
CN101642449B (en) | 2012-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: CHENGDU SHUNFA DISINFECTING AND WASHING SCIENCE AN Free format text: FORMER OWNER: LIANG ZONGGUI Effective date: 20100601 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 610000 NO.2, FLOOR 4, UNIT 3, BUILDING 8, NO.56, DONGYI STREET, JINJIANG DISTRICT, CHENGDU CITY, SICHUAN PROVINCE TO: 610000 PANJIAGOU, JINJIANG DISTRICT, CHENGDU CITY, SICHUAN PROVINCE |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20100601 Address after: 610000 Jinjiang District City, Sichuan Province glass Pan Jia ditch Applicant after: Chengdu Shunfa Disinfectant & Washing Technology Co., Ltd. Address before: 2, No. 4, building 3, 8, 56 Tung Yee Street, Chengdu, Sichuan, Jinjiang District, 610000 Applicant before: Liang Zonggui |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20100210 Assignee: The Taizhou times lauga Health Science and Technology Co Ltd Assignor: Chengdu Shunfa Disinfectant & Washing Technology Co., Ltd. Contract record no.: 2015330000289 Denomination of invention: Skin mucous membrane disinfectants and preparation method thereof Granted publication date: 20120627 License type: Exclusive License Record date: 20151228 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
EC01 | Cancellation of recordation of patent licensing contract | ||
EC01 | Cancellation of recordation of patent licensing contract |
Assignee: The Taizhou times lauga Health Science and Technology Co Ltd Assignor: Chengdu Shunfa Disinfectant & Washing Technology Co., Ltd. Contract record no.: 2015330000289 Date of cancellation: 20190228 |