CN101636102B - 荧光观察装置 - Google Patents

荧光观察装置 Download PDF

Info

Publication number
CN101636102B
CN101636102B CN200880008811.9A CN200880008811A CN101636102B CN 101636102 B CN101636102 B CN 101636102B CN 200880008811 A CN200880008811 A CN 200880008811A CN 101636102 B CN101636102 B CN 101636102B
Authority
CN
China
Prior art keywords
fluorescence
excitation light
light
wavelength
wavelength band
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880008811.9A
Other languages
English (en)
Chinese (zh)
Other versions
CN101636102A (zh
Inventor
大野涉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Publication of CN101636102A publication Critical patent/CN101636102A/zh
Application granted granted Critical
Publication of CN101636102B publication Critical patent/CN101636102B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00004Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00186Optical arrangements with imaging filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200880008811.9A 2007-03-20 2008-03-14 荧光观察装置 Expired - Fee Related CN101636102B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007073391A JP2008229024A (ja) 2007-03-20 2007-03-20 蛍光観察装置
JP073391/2007 2007-03-20
PCT/JP2008/054799 WO2008114748A1 (ja) 2007-03-20 2008-03-14 蛍光観察装置

Publications (2)

Publication Number Publication Date
CN101636102A CN101636102A (zh) 2010-01-27
CN101636102B true CN101636102B (zh) 2011-04-27

Family

ID=39765856

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880008811.9A Expired - Fee Related CN101636102B (zh) 2007-03-20 2008-03-14 荧光观察装置

Country Status (5)

Country Link
US (1) US8188446B2 (https=)
EP (1) EP2127593A4 (https=)
JP (1) JP2008229024A (https=)
CN (1) CN101636102B (https=)
WO (1) WO2008114748A1 (https=)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2291640T3 (en) 2008-05-20 2019-03-11 Univ Health Network Device and method for fluorescence-based imaging and monitoring
CN102333473A (zh) * 2009-03-24 2012-01-25 奥林巴斯医疗株式会社 荧光观察装置
JP2011053135A (ja) * 2009-09-03 2011-03-17 Japan Aerospace Exploration Agency 生体代謝機能評価用多波長蛍光撮影装置及び生体代謝機能評価用多波長蛍光撮影方法
JP5438550B2 (ja) * 2010-02-26 2014-03-12 富士フイルム株式会社 内視鏡用撮像光学系及び内視鏡システム
JP5432793B2 (ja) * 2010-03-29 2014-03-05 オリンパス株式会社 蛍光内視鏡装置
JP5484997B2 (ja) * 2010-04-12 2014-05-07 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
JP5603676B2 (ja) * 2010-06-29 2014-10-08 オリンパス株式会社 画像処理装置及びプログラム
JP5907882B2 (ja) * 2010-10-19 2016-04-26 オリンパス株式会社 単一発光粒子の偏光特性を観測する光分析装置、光分析方法及びそのための光分析用コンピュータプログラム
CN102641117B (zh) * 2011-02-21 2015-08-19 南台科技大学 一种非侵入式人体新陈代谢状态测量装置及方法
EP2756303B1 (en) * 2011-09-15 2018-08-22 The Trustees of Columbia University in the City of New York Measurement of a fluorescent analyte using tissue excitation
ES2727868T3 (es) 2011-09-22 2019-10-21 Univ George Washington Sistemas para visualizar el tejido ablacionado
WO2013044182A1 (en) 2011-09-22 2013-03-28 The George Washington University Systems and methods for visualizing ablated tissue
WO2013100030A1 (ja) * 2011-12-28 2013-07-04 オリンパス株式会社 蛍光観察装置、蛍光観察方法および蛍光観察装置の作動方法
JP5926966B2 (ja) * 2012-01-30 2016-05-25 オリンパス株式会社 蛍光観察装置
US10231626B2 (en) * 2013-03-15 2019-03-19 The Regents Of The University Of California Imaging system and method for fluorescence guided surgery
JP2015068709A (ja) * 2013-09-27 2015-04-13 富士フイルム株式会社 光計測装置
JP6737705B2 (ja) 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム
WO2015077474A1 (en) 2013-11-20 2015-05-28 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
JP6247580B2 (ja) * 2014-03-27 2017-12-13 富士フイルム株式会社 内視鏡装置及びその制御方法
WO2015186397A1 (ja) * 2014-06-05 2015-12-10 オリンパスメディカルシステムズ株式会社 処理装置、内視鏡システム、内視鏡装置、画像処理方法および画像処理プログラム
CN106537906B (zh) * 2014-07-15 2019-03-29 夏普株式会社 摄像装置和分析装置
EP3957232B1 (en) 2014-07-24 2025-12-31 University Health Network DATA COLLECTION AND ANALYSIS FOR DIAGNOSTIC PURPOSES
CN113143440B (zh) 2014-11-03 2024-07-30 乔治华盛顿大学 用于损伤评估的系统和方法
JP6771731B2 (ja) 2014-11-03 2020-10-21 460メディカル・インコーポレイテッド460Medical, Inc. 接触性評価システム及び方法
US10390708B2 (en) * 2015-03-02 2019-08-27 Citizen Watch Co., Ltd. Optical measuring device and toothbrush provided with same
CN106999029A (zh) 2015-05-28 2017-08-01 奥林巴斯株式会社 光源装置
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
JP6762703B2 (ja) * 2015-11-10 2020-09-30 京都府公立大学法人 腫瘍部位の判別のための方法、腫瘍部位の判別装置
AU2017250458A1 (en) * 2016-04-13 2018-11-08 Inspektor Research Systems B.V. Bi-frequency dental examination
US10834377B2 (en) 2016-08-29 2020-11-10 Faro Technologies, Inc. Forensic three-dimensional measurement device
JP6550420B2 (ja) * 2017-06-02 2019-07-24 富士フイルム株式会社 内視鏡装置
WO2018225122A1 (ja) * 2017-06-05 2018-12-13 オリンパス株式会社 内視鏡装置
JP6959849B2 (ja) * 2017-12-07 2021-11-05 Toyo Tire株式会社 接地面観察方法
BR112020015757A2 (pt) * 2018-02-02 2020-12-08 University Health Network Dispositivos, sistemas, e métodos para visualização e remoção de tumor
CN113518910B (zh) 2019-01-17 2025-08-05 莫勒库莱特股份有限公司 用于多模态成像和分析的模块化系统
KR20210118110A (ko) 2019-01-17 2021-09-29 에스비아이 알라파마 캐나다, 인크. 종양 시각화 및 제거를 위한 장치, 시스템 및 방법
US12076081B2 (en) 2020-01-08 2024-09-03 460Medical, Inc. Systems and methods for optical interrogation of ablation lesions
US12539043B2 (en) 2020-05-27 2026-02-03 The George Washington University Lesion visualization using dual wavelength approach
USD1117133S1 (en) 2021-08-23 2026-03-10 Moleculight Inc. Modular handheld imaging device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413108A (en) * 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US6174291B1 (en) * 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
JP4433347B2 (ja) 2000-01-17 2010-03-17 富士フイルム株式会社 蛍光撮像装置
US20030103262A1 (en) * 2001-09-07 2003-06-05 Board Of Regents, The University Of Texas System Multimodal miniature microscope
JP4663273B2 (ja) * 2003-08-08 2011-04-06 オリンパス株式会社 カプセル型光センサー及びそれを用いた診断装置
WO2005069887A2 (en) * 2004-01-16 2005-08-04 The City College Of The University Of New York Micro-scale compact device for in vivo medical diagnosis combining optical imaging and point fluorescence spectroscopy
JP2006122195A (ja) * 2004-10-27 2006-05-18 Olympus Corp 内視鏡光学系
JP5028008B2 (ja) * 2004-12-08 2012-09-19 オリンパス株式会社 蛍光内視鏡装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP特开2003-250752A 2003.09.09

Also Published As

Publication number Publication date
US8188446B2 (en) 2012-05-29
WO2008114748A1 (ja) 2008-09-25
EP2127593A1 (en) 2009-12-02
CN101636102A (zh) 2010-01-27
US20100084563A1 (en) 2010-04-08
JP2008229024A (ja) 2008-10-02
EP2127593A4 (en) 2012-09-12

Similar Documents

Publication Publication Date Title
CN101636102B (zh) 荧光观察装置
EP2105082B1 (en) Fluorescence observing device and fluorescence observing method
JP5466182B2 (ja) 内視鏡システムおよび内視鏡システムの作動方法
JP4749805B2 (ja) ラマン散乱光観測装置
JP4818753B2 (ja) 内視鏡システム
US20060247537A1 (en) Endoscope apparatus
EP2213222B1 (en) Fluorescence endoscope system
JP2006061683A (ja) 内視鏡装置
JP5721940B2 (ja) 光スペクトル検出方法
JP5506472B2 (ja) 蛍光内視鏡装置
US8039816B2 (en) Fluorescence observation apparatus
JP2018089109A (ja) 内視鏡装置及び内視鏡装置の作動方法
JP5752423B2 (ja) 分光計測システムおよび分光計測システムの作動方法
CN108024696A (zh) 内窥镜装置
US20070285771A1 (en) Endoscope system
WO2014199984A1 (ja) 手術用顕微鏡システム
JP5142564B2 (ja) 蛍光内視鏡装置
JP2011097987A (ja) 内視鏡装置
JP5242078B2 (ja) 蛍光内視鏡装置
WO2016194101A1 (ja) 赤外蛍光観察装置
JPWO2009072177A1 (ja) 分光観察装置、内視鏡システムおよびカプセル内視鏡システム
WO2015025595A1 (ja) 内視鏡システム及び作動方法
JP2008043493A (ja) 蛍光内視鏡システム
JP6120770B2 (ja) 分光画像取得装置
JP4919780B2 (ja) 蛍光観察装置

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110427

Termination date: 20180314