WO2008114748A1 - 蛍光観察装置 - Google Patents

蛍光観察装置 Download PDF

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Publication number
WO2008114748A1
WO2008114748A1 PCT/JP2008/054799 JP2008054799W WO2008114748A1 WO 2008114748 A1 WO2008114748 A1 WO 2008114748A1 JP 2008054799 W JP2008054799 W JP 2008054799W WO 2008114748 A1 WO2008114748 A1 WO 2008114748A1
Authority
WO
WIPO (PCT)
Prior art keywords
excitation light
fluorescence
monitored
subject
detected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/054799
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
Wataru Ohno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to CN200880008811.9A priority Critical patent/CN101636102B/zh
Priority to EP08722195A priority patent/EP2127593A4/en
Priority to US12/531,604 priority patent/US8188446B2/en
Publication of WO2008114748A1 publication Critical patent/WO2008114748A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PCT/JP2008/054799 2007-03-20 2008-03-14 蛍光観察装置 Ceased WO2008114748A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN200880008811.9A CN101636102B (zh) 2007-03-20 2008-03-14 荧光观察装置
EP08722195A EP2127593A4 (en) 2007-03-20 2008-03-14 FLUORESCENCE MONITORING APPARATUS
US12/531,604 US8188446B2 (en) 2007-03-20 2008-03-14 Fluorescence imaging apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-073391 2007-03-20
JP2007073391A JP2008229024A (ja) 2007-03-20 2007-03-20 蛍光観察装置

Publications (1)

Publication Number Publication Date
WO2008114748A1 true WO2008114748A1 (ja) 2008-09-25

Family

ID=39765856

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054799 Ceased WO2008114748A1 (ja) 2007-03-20 2008-03-14 蛍光観察装置

Country Status (5)

Country Link
US (1) US8188446B2 (https=)
EP (1) EP2127593A4 (https=)
JP (1) JP2008229024A (https=)
CN (1) CN101636102B (https=)
WO (1) WO2008114748A1 (https=)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110213204A1 (en) * 2010-02-26 2011-09-01 Osamu Kuroda Endoscope system and imaging device thereof
CN102333473A (zh) * 2009-03-24 2012-01-25 奥林巴斯医疗株式会社 荧光观察装置
US9014789B2 (en) 2011-09-22 2015-04-21 The George Washington University Systems and methods for visualizing ablated tissue
US9084611B2 (en) 2011-09-22 2015-07-21 The George Washington University Systems and methods for visualizing ablated tissue
US10143517B2 (en) 2014-11-03 2018-12-04 LuxCath, LLC Systems and methods for assessment of contact quality
US10722301B2 (en) 2014-11-03 2020-07-28 The George Washington University Systems and methods for lesion assessment
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US11096584B2 (en) 2013-11-14 2021-08-24 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US11457817B2 (en) 2013-11-20 2022-10-04 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
US12076081B2 (en) 2020-01-08 2024-09-03 460Medical, Inc. Systems and methods for optical interrogation of ablation lesions
US12539043B2 (en) 2020-05-27 2026-02-03 The George Washington University Lesion visualization using dual wavelength approach

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2291640T3 (en) 2008-05-20 2019-03-11 Univ Health Network Device and method for fluorescence-based imaging and monitoring
JP2011053135A (ja) * 2009-09-03 2011-03-17 Japan Aerospace Exploration Agency 生体代謝機能評価用多波長蛍光撮影装置及び生体代謝機能評価用多波長蛍光撮影方法
JP5432793B2 (ja) * 2010-03-29 2014-03-05 オリンパス株式会社 蛍光内視鏡装置
JP5484997B2 (ja) * 2010-04-12 2014-05-07 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
JP5603676B2 (ja) * 2010-06-29 2014-10-08 オリンパス株式会社 画像処理装置及びプログラム
JP5907882B2 (ja) * 2010-10-19 2016-04-26 オリンパス株式会社 単一発光粒子の偏光特性を観測する光分析装置、光分析方法及びそのための光分析用コンピュータプログラム
CN102641117B (zh) * 2011-02-21 2015-08-19 南台科技大学 一种非侵入式人体新陈代谢状态测量装置及方法
EP2756303B1 (en) * 2011-09-15 2018-08-22 The Trustees of Columbia University in the City of New York Measurement of a fluorescent analyte using tissue excitation
WO2013100030A1 (ja) * 2011-12-28 2013-07-04 オリンパス株式会社 蛍光観察装置、蛍光観察方法および蛍光観察装置の作動方法
JP5926966B2 (ja) * 2012-01-30 2016-05-25 オリンパス株式会社 蛍光観察装置
US10231626B2 (en) * 2013-03-15 2019-03-19 The Regents Of The University Of California Imaging system and method for fluorescence guided surgery
JP2015068709A (ja) * 2013-09-27 2015-04-13 富士フイルム株式会社 光計測装置
JP6247580B2 (ja) * 2014-03-27 2017-12-13 富士フイルム株式会社 内視鏡装置及びその制御方法
WO2015186397A1 (ja) * 2014-06-05 2015-12-10 オリンパスメディカルシステムズ株式会社 処理装置、内視鏡システム、内視鏡装置、画像処理方法および画像処理プログラム
CN106537906B (zh) * 2014-07-15 2019-03-29 夏普株式会社 摄像装置和分析装置
EP3957232B1 (en) 2014-07-24 2025-12-31 University Health Network DATA COLLECTION AND ANALYSIS FOR DIAGNOSTIC PURPOSES
US10390708B2 (en) * 2015-03-02 2019-08-27 Citizen Watch Co., Ltd. Optical measuring device and toothbrush provided with same
CN106999029A (zh) 2015-05-28 2017-08-01 奥林巴斯株式会社 光源装置
JP6762703B2 (ja) * 2015-11-10 2020-09-30 京都府公立大学法人 腫瘍部位の判別のための方法、腫瘍部位の判別装置
AU2017250458A1 (en) * 2016-04-13 2018-11-08 Inspektor Research Systems B.V. Bi-frequency dental examination
US10834377B2 (en) 2016-08-29 2020-11-10 Faro Technologies, Inc. Forensic three-dimensional measurement device
JP6550420B2 (ja) * 2017-06-02 2019-07-24 富士フイルム株式会社 内視鏡装置
WO2018225122A1 (ja) * 2017-06-05 2018-12-13 オリンパス株式会社 内視鏡装置
JP6959849B2 (ja) * 2017-12-07 2021-11-05 Ｔｏｙｏ Ｔｉｒｅ株式会社 接地面観察方法
BR112020015757A2 (pt) * 2018-02-02 2020-12-08 University Health Network Dispositivos, sistemas, e métodos para visualização e remoção de tumor
CN113518910B (zh) 2019-01-17 2025-08-05 莫勒库莱特股份有限公司 用于多模态成像和分析的模块化系统
KR20210118110A (ko) 2019-01-17 2021-09-29 에스비아이 알라파마 캐나다, 인크. 종양 시각화 및 제거를 위한 장치, 시스템 및 방법
USD1117133S1 (en) 2021-08-23 2026-03-10 Moleculight Inc. Modular handheld imaging device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0654792A (ja) * 1991-05-08 1994-03-01 Xillix Technol Corp 撮像装置
JPH09308604A (ja) * 1996-03-06 1997-12-02 Fuji Photo Film Co Ltd 蛍光検出装置
JP2001190489A (ja) 2000-01-17 2001-07-17 Fuji Photo Film Co Ltd 蛍光撮像装置
JP3683271B2 (ja) 1994-03-28 2005-08-17 ジリックス・テクノロジイズ・コーポレーション 積分された内部蛍光を使用して病気の組織の画像を映すための装置および方法
JP2006187598A (ja) * 2004-12-08 2006-07-20 Olympus Corp 蛍光内視鏡装置及びそれに用いる撮像ユニット

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5413108A (en) * 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US6174291B1 (en) * 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
US20030103262A1 (en) * 2001-09-07 2003-06-05 Board Of Regents, The University Of Texas System Multimodal miniature microscope
JP3848623B2 (ja) * 2003-01-16 2006-11-22 松下電器産業株式会社 蛍光測定装置
JP4663273B2 (ja) * 2003-08-08 2011-04-06 オリンパス株式会社 カプセル型光センサー及びそれを用いた診断装置
WO2005069887A2 (en) * 2004-01-16 2005-08-04 The City College Of The University Of New York Micro-scale compact device for in vivo medical diagnosis combining optical imaging and point fluorescence spectroscopy
JP2006122195A (ja) * 2004-10-27 2006-05-18 Olympus Corp 内視鏡光学系

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0654792A (ja) * 1991-05-08 1994-03-01 Xillix Technol Corp 撮像装置
JP3683271B2 (ja) 1994-03-28 2005-08-17 ジリックス・テクノロジイズ・コーポレーション 積分された内部蛍光を使用して病気の組織の画像を映すための装置および方法
JPH09308604A (ja) * 1996-03-06 1997-12-02 Fuji Photo Film Co Ltd 蛍光検出装置
JP2001190489A (ja) 2000-01-17 2001-07-17 Fuji Photo Film Co Ltd 蛍光撮像装置
JP2006187598A (ja) * 2004-12-08 2006-07-20 Olympus Corp 蛍光内視鏡装置及びそれに用いる撮像ユニット

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2127593A4

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102333473A (zh) * 2009-03-24 2012-01-25 奥林巴斯医疗株式会社 荧光观察装置
US20110213204A1 (en) * 2010-02-26 2011-09-01 Osamu Kuroda Endoscope system and imaging device thereof
US9014789B2 (en) 2011-09-22 2015-04-21 The George Washington University Systems and methods for visualizing ablated tissue
US9084611B2 (en) 2011-09-22 2015-07-21 The George Washington University Systems and methods for visualizing ablated tissue
US10076238B2 (en) 2011-09-22 2018-09-18 The George Washington University Systems and methods for visualizing ablated tissue
US12075980B2 (en) 2011-09-22 2024-09-03 The George Washington University Systems and methods for visualizing ablated tissue
US10716462B2 (en) 2011-09-22 2020-07-21 The George Washington University Systems and methods for visualizing ablated tissue
US10736512B2 (en) 2011-09-22 2020-08-11 The George Washington University Systems and methods for visualizing ablated tissue
US11559192B2 (en) 2011-09-22 2023-01-24 The George Washington University Systems and methods for visualizing ablated tissue
US12343114B2 (en) 2013-11-14 2025-07-01 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US11096584B2 (en) 2013-11-14 2021-08-24 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US11457817B2 (en) 2013-11-20 2022-10-04 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
US11596472B2 (en) 2014-11-03 2023-03-07 460Medical, Inc. Systems and methods for assessment of contact quality
US11559352B2 (en) 2014-11-03 2023-01-24 The George Washington University Systems and methods for lesion assessment
US10722301B2 (en) 2014-11-03 2020-07-28 The George Washington University Systems and methods for lesion assessment
US10682179B2 (en) 2014-11-03 2020-06-16 460Medical, Inc. Systems and methods for determining tissue type
US10143517B2 (en) 2014-11-03 2018-12-04 LuxCath, LLC Systems and methods for assessment of contact quality
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US12295795B2 (en) 2015-07-19 2025-05-13 460Medical, Inc. Systems and methods for lesion formation and assessment
US12076081B2 (en) 2020-01-08 2024-09-03 460Medical, Inc. Systems and methods for optical interrogation of ablation lesions
US12539043B2 (en) 2020-05-27 2026-02-03 The George Washington University Lesion visualization using dual wavelength approach

Also Published As

Publication number Publication date
US8188446B2 (en) 2012-05-29
EP2127593A1 (en) 2009-12-02
CN101636102A (zh) 2010-01-27
US20100084563A1 (en) 2010-04-08
JP2008229024A (ja) 2008-10-02
CN101636102B (zh) 2011-04-27
EP2127593A4 (en) 2012-09-12

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