CN101636102B - 荧光观察装置 - Google Patents

荧光观察装置 Download PDF

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Publication number
CN101636102B
CN101636102B CN200880008811.9A CN200880008811A CN101636102B CN 101636102 B CN101636102 B CN 101636102B CN 200880008811 A CN200880008811 A CN 200880008811A CN 101636102 B CN101636102 B CN 101636102B
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China
Prior art keywords
fluorescence
excitation light
light
wavelength
wavelength band
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Expired - Fee Related
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CN200880008811.9A
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English (en)
Chinese (zh)
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CN101636102A (zh
Inventor
大野涉
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Olympus Corp
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Olympus Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200880008811.9A 2007-03-20 2008-03-14 荧光观察装置 Expired - Fee Related CN101636102B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP073391/2007 2007-03-20
JP2007073391A JP2008229024A (ja) 2007-03-20 2007-03-20 蛍光観察装置
PCT/JP2008/054799 WO2008114748A1 (ja) 2007-03-20 2008-03-14 蛍光観察装置

Publications (2)

Publication Number Publication Date
CN101636102A CN101636102A (zh) 2010-01-27
CN101636102B true CN101636102B (zh) 2011-04-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880008811.9A Expired - Fee Related CN101636102B (zh) 2007-03-20 2008-03-14 荧光观察装置

Country Status (5)

Country Link
US (1) US8188446B2 (enExample)
EP (1) EP2127593A4 (enExample)
JP (1) JP2008229024A (enExample)
CN (1) CN101636102B (enExample)
WO (1) WO2008114748A1 (enExample)

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CA2724973C (en) 2008-05-20 2015-08-11 University Health Network Device and method for fluorescence-based imaging and monitoring
WO2010109707A1 (ja) * 2009-03-24 2010-09-30 オリンパスメディカルシステムズ株式会社 蛍光観察装置
JP2011053135A (ja) * 2009-09-03 2011-03-17 Japan Aerospace Exploration Agency 生体代謝機能評価用多波長蛍光撮影装置及び生体代謝機能評価用多波長蛍光撮影方法
JP5438550B2 (ja) * 2010-02-26 2014-03-12 富士フイルム株式会社 内視鏡用撮像光学系及び内視鏡システム
JP5432793B2 (ja) * 2010-03-29 2014-03-05 オリンパス株式会社 蛍光内視鏡装置
JP5484997B2 (ja) * 2010-04-12 2014-05-07 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
JP5603676B2 (ja) * 2010-06-29 2014-10-08 オリンパス株式会社 画像処理装置及びプログラム
CN103210302B (zh) * 2010-10-19 2015-05-27 奥林巴斯株式会社 观测单个发光粒子的偏振特性的光分析装置、光分析方法
CN102641117B (zh) * 2011-02-21 2015-08-19 南台科技大学 一种非侵入式人体新陈代谢状态测量装置及方法
EP2756303B1 (en) * 2011-09-15 2018-08-22 The Trustees of Columbia University in the City of New York Measurement of a fluorescent analyte using tissue excitation
EP2757933B1 (en) 2011-09-22 2019-02-06 The George Washington University Systems for visualizing ablated tissue
JP5926806B2 (ja) 2011-09-22 2016-05-25 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity アブレーションされた組織を視覚化するシステムと方法
JP6141196B2 (ja) * 2011-12-28 2017-06-07 オリンパス株式会社 蛍光観察装置
JP5926966B2 (ja) * 2012-01-30 2016-05-25 オリンパス株式会社 蛍光観察装置
US10231626B2 (en) * 2013-03-15 2019-03-19 The Regents Of The University Of California Imaging system and method for fluorescence guided surgery
JP2015068709A (ja) * 2013-09-27 2015-04-13 富士フイルム株式会社 光計測装置
JP6737705B2 (ja) 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム
JP2017500550A (ja) 2013-11-20 2017-01-05 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity 心臓組織のハイパースペクトル分析のためのシステム及び方法
JP6247580B2 (ja) * 2014-03-27 2017-12-13 富士フイルム株式会社 内視鏡装置及びその制御方法
CN106455942B (zh) * 2014-06-05 2018-07-06 奥林巴斯株式会社 处理装置、内窥镜装置及系统、图像处理装置的工作方法
JP6378767B2 (ja) * 2014-07-15 2018-08-22 シャープ株式会社 撮像装置、及び解析装置
WO2016011534A1 (en) 2014-07-24 2016-01-28 University Health Network Collection and analysis of data for diagnostic purposes
CN113208723B (zh) 2014-11-03 2024-09-20 460医学股份有限公司 用于接触质量的评估的系统和方法
CN113143440B (zh) 2014-11-03 2024-07-30 乔治华盛顿大学 用于损伤评估的系统和方法
EP3267182B1 (en) * 2015-03-02 2022-02-23 Citizen Watch Co., Ltd. Optical measuring device and toothbrush provided with same
CN106999029A (zh) 2015-05-28 2017-08-01 奥林巴斯株式会社 光源装置
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
JP6762703B2 (ja) * 2015-11-10 2020-09-30 京都府公立大学法人 腫瘍部位の判別のための方法、腫瘍部位の判別装置
CN109475285B (zh) * 2016-04-13 2021-07-06 检查员研究系统公司 双频牙齿检查
US10834377B2 (en) 2016-08-29 2020-11-10 Faro Technologies, Inc. Forensic three-dimensional measurement device
JP6550420B2 (ja) * 2017-06-02 2019-07-24 富士フイルム株式会社 内視鏡装置
WO2018225122A1 (ja) * 2017-06-05 2018-12-13 オリンパス株式会社 内視鏡装置
JP6959849B2 (ja) * 2017-12-07 2021-11-05 Toyo Tire株式会社 接地面観察方法
MX2020008159A (es) * 2018-02-02 2021-02-02 Univ Health Network Dispositivos, sistemas y metodos para la visualizacion y eliminacion de tumores.
AU2020208843A1 (en) 2019-01-17 2021-08-05 Moleculight Inc. Modular system for multi-modal imaging and analysis
US12575735B2 (en) 2019-01-17 2026-03-17 SBI ALApharma Canada Inc. Devices, systems, and methods for tumor visualization and removal
US12076081B2 (en) 2020-01-08 2024-09-03 460Medical, Inc. Systems and methods for optical interrogation of ablation lesions
US12539043B2 (en) 2020-05-27 2026-02-03 The George Washington University Lesion visualization using dual wavelength approach
USD1117133S1 (en) 2021-08-23 2026-03-10 Moleculight Inc. Modular handheld imaging device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

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US5413108A (en) * 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US6174291B1 (en) * 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
JP4433347B2 (ja) 2000-01-17 2010-03-17 富士フイルム株式会社 蛍光撮像装置
WO2003023479A1 (en) * 2001-09-07 2003-03-20 Board Of Regents, The University Of Texas System Multimodal miniature microscope
JP4663273B2 (ja) * 2003-08-08 2011-04-06 オリンパス株式会社 カプセル型光センサー及びそれを用いた診断装置
JP2007525261A (ja) * 2004-01-16 2007-09-06 ザ シティ カレッジ オブ ザ シティ ユニバーシティ オブ ニューヨーク 光学式画像化とポイント蛍光分光学とを組み合わせたインビボ医療診断のためのマイクロスケールコンパクトデバイス
JP2006122195A (ja) * 2004-10-27 2006-05-18 Olympus Corp 内視鏡光学系
JP5028008B2 (ja) * 2004-12-08 2012-09-19 オリンパス株式会社 蛍光内視鏡装置

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
JP2008229024A (ja) 2008-10-02
US20100084563A1 (en) 2010-04-08
EP2127593A1 (en) 2009-12-02
US8188446B2 (en) 2012-05-29
CN101636102A (zh) 2010-01-27
EP2127593A4 (en) 2012-09-12
WO2008114748A1 (ja) 2008-09-25

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Granted publication date: 20110427

Termination date: 20180314