CN101636102B - 荧光观察装置 - Google Patents

荧光观察装置 Download PDF

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Publication number
CN101636102B
CN101636102B CN200880008811.9A CN200880008811A CN101636102B CN 101636102 B CN101636102 B CN 101636102B CN 200880008811 A CN200880008811 A CN 200880008811A CN 101636102 B CN101636102 B CN 101636102B
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CN
China
Prior art keywords
fluorescence
excitation light
light
wavelength
wavelength band
Prior art date
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Expired - Fee Related
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CN200880008811.9A
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English (en)
Chinese (zh)
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CN101636102A (zh
Inventor
大野涉
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Olympus Corp
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Olympus Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200880008811.9A 2007-03-20 2008-03-14 荧光观察装置 Expired - Fee Related CN101636102B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP073391/2007 2007-03-20
JP2007073391A JP2008229024A (ja) 2007-03-20 2007-03-20 蛍光観察装置
PCT/JP2008/054799 WO2008114748A1 (ja) 2007-03-20 2008-03-14 蛍光観察装置

Publications (2)

Publication Number Publication Date
CN101636102A CN101636102A (zh) 2010-01-27
CN101636102B true CN101636102B (zh) 2011-04-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880008811.9A Expired - Fee Related CN101636102B (zh) 2007-03-20 2008-03-14 荧光观察装置

Country Status (5)

Country Link
US (1) US8188446B2 (enExample)
EP (1) EP2127593A4 (enExample)
JP (1) JP2008229024A (enExample)
CN (1) CN101636102B (enExample)
WO (1) WO2008114748A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102099671A (zh) 2008-05-20 2011-06-15 大学健康网络 用于基于荧光的成像和监测的装置和方法
CN102333473A (zh) * 2009-03-24 2012-01-25 奥林巴斯医疗株式会社 荧光观察装置
JP2011053135A (ja) * 2009-09-03 2011-03-17 Japan Aerospace Exploration Agency 生体代謝機能評価用多波長蛍光撮影装置及び生体代謝機能評価用多波長蛍光撮影方法
JP5438550B2 (ja) * 2010-02-26 2014-03-12 富士フイルム株式会社 内視鏡用撮像光学系及び内視鏡システム
JP5432793B2 (ja) * 2010-03-29 2014-03-05 オリンパス株式会社 蛍光内視鏡装置
JP5484997B2 (ja) * 2010-04-12 2014-05-07 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
JP5603676B2 (ja) * 2010-06-29 2014-10-08 オリンパス株式会社 画像処理装置及びプログラム
EP2620763A4 (en) * 2010-10-19 2015-05-27 Olympus Corp OPTICAL ANALYSIS DEVICE FOR OBSERVING THE POLARIZATION CHARACTERISTICS OF A SINGLE LIGHT-EMITTING PARTICLE, OPTICAL ANALYSIS METHOD, AND OPTICAL ANALYSIS COMPUTER PROGRAM
CN102641117B (zh) * 2011-02-21 2015-08-19 南台科技大学 一种非侵入式人体新陈代谢状态测量装置及方法
PH12014500517A1 (en) * 2011-09-15 2014-04-14 Univ Columbia Measurement of a fluorescent analyte using tissue excitation
US9084611B2 (en) 2011-09-22 2015-07-21 The George Washington University Systems and methods for visualizing ablated tissue
EP2757933B1 (en) 2011-09-22 2019-02-06 The George Washington University Systems for visualizing ablated tissue
JP6141196B2 (ja) * 2011-12-28 2017-06-07 オリンパス株式会社 蛍光観察装置
JP5926966B2 (ja) * 2012-01-30 2016-05-25 オリンパス株式会社 蛍光観察装置
US10231626B2 (en) * 2013-03-15 2019-03-19 The Regents Of The University Of California Imaging system and method for fluorescence guided surgery
JP2015068709A (ja) * 2013-09-27 2015-04-13 富士フイルム株式会社 光計測装置
WO2015073871A2 (en) 2013-11-14 2015-05-21 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US20150141847A1 (en) 2013-11-20 2015-05-21 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
JP6247580B2 (ja) * 2014-03-27 2017-12-13 富士フイルム株式会社 内視鏡装置及びその制御方法
WO2015186397A1 (ja) * 2014-06-05 2015-12-10 オリンパスメディカルシステムズ株式会社 処理装置、内視鏡システム、内視鏡装置、画像処理方法および画像処理プログラム
CN106537906B (zh) * 2014-07-15 2019-03-29 夏普株式会社 摄像装置和分析装置
EP3171765B1 (en) 2014-07-24 2021-09-01 University Health Network Collection and analysis of data for diagnostic purposes
KR102612185B1 (ko) 2014-11-03 2023-12-08 460메디컬, 인크. 접촉 품질의 평가를 위한 시스템 및 방법
EP3215002B1 (en) 2014-11-03 2024-03-20 The George Washington University Systems for lesion assessment
JP6681875B2 (ja) * 2015-03-02 2020-04-15 シチズン時計株式会社 光測定装置及びこれを備えた歯ブラシ
EP3216385A4 (en) * 2015-05-28 2018-08-22 Olympus Corporation Light source device
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
JP6762703B2 (ja) * 2015-11-10 2020-09-30 京都府公立大学法人 腫瘍部位の判別のための方法、腫瘍部位の判別装置
ES2886082T3 (es) * 2016-04-13 2021-12-16 Inspektor Res Systems B V Examen dental bifrecuencia
US10834377B2 (en) 2016-08-29 2020-11-10 Faro Technologies, Inc. Forensic three-dimensional measurement device
JP6550420B2 (ja) * 2017-06-02 2019-07-24 富士フイルム株式会社 内視鏡装置
WO2018225122A1 (ja) * 2017-06-05 2018-12-13 オリンパス株式会社 内視鏡装置
JP6959849B2 (ja) * 2017-12-07 2021-11-05 Ｔｏｙｏ Ｔｉｒｅ株式会社 接地面観察方法
CN112004459A (zh) * 2018-02-02 2020-11-27 大学健康网络 用于肿瘤可视化和切除的装置、系统和方法
JP7648525B2 (ja) 2019-01-17 2025-03-18 モレキュライト・インコーポレイテッド マルチモーダル撮像および解析のためのモジュールシステム
EP4087511A4 (en) 2020-01-08 2024-02-14 460Medical, Inc. SYSTEMS AND METHODS FOR OPTICAL INQUIRY OF ABLATION INJURIES

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413108A (en) * 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US5590660A (en) * 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US6174291B1 (en) * 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
JP4433347B2 (ja) 2000-01-17 2010-03-17 富士フイルム株式会社 蛍光撮像装置
US20030103262A1 (en) * 2001-09-07 2003-06-05 Board Of Regents, The University Of Texas System Multimodal miniature microscope
JP4663273B2 (ja) * 2003-08-08 2011-04-06 オリンパス株式会社 カプセル型光センサー及びそれを用いた診断装置
JP2007525261A (ja) * 2004-01-16 2007-09-06 ザ シティ カレッジ オブ ザ シティ ユニバーシティ オブ ニューヨーク 光学式画像化とポイント蛍光分光学とを組み合わせたインビボ医療診断のためのマイクロスケールコンパクトデバイス
JP2006122195A (ja) * 2004-10-27 2006-05-18 Olympus Corp 内視鏡光学系
JP5028008B2 (ja) * 2004-12-08 2012-09-19 オリンパス株式会社 蛍光内視鏡装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512965A1 (en) * 1991-05-08 1992-11-11 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
US5371624A (en) * 1991-11-29 1994-12-06 Olympus Optical Co., Ltd. Reflected fluorescence microscope
US5833617A (en) * 1996-03-06 1998-11-10 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
CN1714288A (zh) * 2003-01-16 2005-12-28 松下电器产业株式会社 荧光计

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP特开2003-250752A 2003.09.09

Also Published As

Publication number Publication date
US20100084563A1 (en) 2010-04-08
WO2008114748A1 (ja) 2008-09-25
EP2127593A4 (en) 2012-09-12
US8188446B2 (en) 2012-05-29
JP2008229024A (ja) 2008-10-02
CN101636102A (zh) 2010-01-27
EP2127593A1 (en) 2009-12-02

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Granted publication date: 20110427

Termination date: 20180314