CN101612293B - Traditional Chinese medicine composition for treating joint type psoriasis - Google Patents
Traditional Chinese medicine composition for treating joint type psoriasis Download PDFInfo
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- CN101612293B CN101612293B CN2009100655996A CN200910065599A CN101612293B CN 101612293 B CN101612293 B CN 101612293B CN 2009100655996 A CN2009100655996 A CN 2009100655996A CN 200910065599 A CN200910065599 A CN 200910065599A CN 101612293 B CN101612293 B CN 101612293B
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Abstract
The invention belongs to the technical field of the traditional Chinese medicine, which especially discloses a traditional Chinese medicine composition for treating joint type psoriasis. The traditional Chinese medicine composition is prepared from the following raw material medicines according to parts by weight: 15 to 30 parts of black-tail snake, 6 to 15 parts of scorpio, 6 to 15 parts of centipede, 10 to 15 parts of cicada slough, 15 to 30 parts of radix rehmanniae, 15 to 30 parts of bistortae, 15 to 30 parts of oldenlandia diffusa, 10 to 20 parts of angelica, 15 to 50 parts of radix salviae miltiorrhizae, 10 to 20 parts of red peony root, 15 to 60 parts of spatholobus stem, 10 to 15 parts of radix gentianae macrophyllae, 10 to 30 parts of uncaria, 10 to 20 parts of muscardine silkworm, 10 to 20 parts of rhizoma seu radix notopterygii, 10 to 15 parts of futokadsura stem, 6 to 15 parts of crude licorice and 15 to 30 parts of smilax glabra rhizoma. The traditional Chinese medicine composition has very strong pertinence to the therapy of the joint type psoriasis, the cure rate is as high as 94%, and relapse is not easy to occur after being used.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly the psoriasic Chinese medicine composition of a kind of treatment joint type.
Background technology
Psoriasis is a kind of relatively more obstinate chronic disease, though the life of human body is not constituted too big threat, this disease brings people endless worries.According to clinical manifestation and pathological characters, psoriasis mainly is divided into four types of homeliness type psoriasis, pustule type psoriasis, arthrosis type psoriasis and erythrodermic psoriasiss.The psoriasic main feature of arthrosis type is the performance that also has joint damage except that skin lesion, also is arthritic psoriasis, and its joint symptom often increases the weight of simultaneously with skin symptom or alleviates.The arthrosis state of an illness of most cases often is secondary to after the psoriasis, or repeatedly fall ill back severity of symptoms and the joint takes place change of psoriasis, or concurrent with pustule type psoriasis or erythrodermic psoriasis.This arthritis can betide big or small joint simultaneously, also is found in spinal column, but with little joints such as hands, wrist and foots for seeing more, with finger (toe) joint, be meant that especially (toe) terminal joint involvement is more general especially.The psoriasic patient of arthrosis type gets involved the joint can be red and swollen, sharp ache, the big joint of weight person can hydrops, near skin is also normal red and swollen, the activity in joint is gradually restricted, for a long time after, the joint is variable tetanic, influences function of joint.In general, psoriasic medical history is permanent more, outbreak more repeatedly, the easy more joint damage that causes.The first psoriatic who sends out, the less joint symptom that occurs.Arthrosis type psoriatic is through the X ray examination, can see that cartilage disappears, and articular surface corrodes, and the joint space narrows down, soft tissue swelling, osteoporosis, dissolving or with bony ankylosis.This disease will be distinguished mutually with rheumatoid arthritis.The former many psoriasis medical histories with for many years, joint involvement is based on little joint, and is often asymmetric, the middle rheumatoid factor negative of having a blood test, and often with the infringement of fingernail.
But up to now, also do not find the psoriasic specific medicament of a kind of treatment joint type, most drug can only play certain effect at short notice, still can show effect repeatedly after the drug withdrawal, brings great misery for patient's spirit.
Summary of the invention
The object of the present invention is to provide a kind of cure rate height, be difficult for the psoriasic Chinese medicine composition of treatment joint type of recurrence with the back.
For achieving the above object, the technical solution used in the present invention is as follows:
The psoriasic Chinese medicine composition of a kind of treatment joint type is made by each crude drug of following portions by weight: 15～30 parts of Zaocyss, 6～15 parts of Scorpios, 6～15 parts of Scolopendras, 10～15 parts of Periostracum Cicadaes, 15～30 parts of Radix Rehmanniae, 15～30 parts of Rhizoma Paridis, 15～30 parts of Herba Hedyotidis Diffusaes, 10～20 parts of Radix Angelicae Sinensis, 15～50 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Paeoniae Rubra, 15～60 parts of Caulis Spatholobis, 10～15 parts of Radix Gentianae Macrophyllae, 10～30 parts of Gamdir Vine, 10～20 parts of Bombyx Batryticatus, 10～20 parts of Rhizoma Et Radix Notopterygiis, 10～15 parts of Caulis Piperis Kadsuraes, 6～15 parts of Radix Glycyrrhizae, 15～30 parts of Rhizoma Smilacis Glabraes.
Further, the parts by weight of described each crude drug are: 15 parts of Zaocyss, 6 parts of Scorpios, 6 parts of Scolopendras, 10 parts of Periostracum Cicadaes, 15 parts of Radix Rehmanniae, 15 parts of Rhizoma Paridis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Paeoniae Rubra, 30 parts of Caulis Spatholobis, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Gamdir Vine, 10 parts of Bombyx Batryticatus, 10 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Caulis Piperis Kadsuraes, 6 parts of Radix Glycyrrhizae, 15 parts of Rhizoma Smilacis Glabraes.
To be the inventor get in conjunction with the Coryza Treated by Syndrome Differentiation principle prescription of motherland's Chinese medicine according to oneself clinical experience Chinese medicine composition of the present invention, and dialectical joint type psoriasis is that rheumatism is accumulate poison, due to the numbness resistance meridians, and the suitable heat-clearing and toxic substances removing of treatment, promoting blood circulation to remove obstruction in the collateral, assistant is with expelling wind and removing dampness.In each crude drug: Zaocys, the another name Zaocys, sweet, salty, flat, go into lung, spleen two warps, energy wind-damp dispelling, the meridian dredging; Scorpio, Scolopendra, hot, flat, poisonous, return Liver Channel, with the effect of tool endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Periostracum Cicadae, salty, sweet, cold, nontoxic, return lung, Liver Channel, have diffusing wind heat, lung qi dispersing, decide the effect of convulsion; Radix Rehmanniae is commonly called as the Radix Rehmanniae, and nature and flavor are sweet, bitter, cold, and GUIXIN, liver, lung meridian have the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Rhizoma Paridis, another name Rhizoma Paridis, Rhizoma Paridis, Liver Channel is gone in little hardship, cold, slightly poisonous, has the effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Herba Hedyotidis Diffusae, the another name Herba Hedyotidis Diffusae, bitter but sweet flavor, warm in nature, nontoxic, go into the heart, liver, spleen three warps, have the function of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain; Radix Angelicae Sinensis, sweet in the mouth, suffering, warm in nature, return liver, the heart, spleen channel, having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving; Radix Salviae Miltiorrhizae, bitter, be slightly cold, GUIXIN, pericardium, Liver Channel have the effect that promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, relieving restlessness are calmed the nerves; Radix Paeoniae Rubra, hardship is slightly cold, and returns Liver Channel, has clearing away heat and cooling blood, the effect of eliminating stasis to stop pain; Caulis Spatholobi, bitter sweet, warm, go into the heart, spleen two warps, have the effect of relaxing muscles and tendons to promote blood circulation; Radix Gentianae Macrophyllae, toil, flat is gone into liver, stomach, gallbladder meridian, has the effect of expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, clearing away heat and promoting diuresis; Gamdir Vine is commonly called as Ramulus Uncariae Cum Uncis, and is sweet, be slightly cold, and goes into liver, pericardium channel, has the effect of heat clearing away suppressing the hyperactive liver, endogenous wind stopping spasmolytic; Bombyx Batryticatus, salty, flat, hot, return liver, lung meridian, have the effect of endogenous wind stopping relieving convulsion, wind-expelling pain-stopping, dissipating phlegm and resolving masses; Rhizoma Et Radix Notopterygii, arduous, warm, go into bladder, kidney channel, loose exterior cold, wind-damp dispelling, sharp joint; Caulis Piperis Kadsurae, arduous, tepor is gone into the heart, kidney two warps, wind-damp dispelling, the meridian dredging, regulates the flow of vital energy, controls arthralgia; Radix Glycyrrhizae, sweet, flat, GUIXIN, lung, spleen, stomach warp, nourshing blood and promoting blood circulation, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription; Rhizoma Smilacis Glabrae, nature and flavor are sweet, light flat, return liver, and the stomach warp has the effect in detoxifcation dehumidifying, sharp joint.More than the mutual compatibility of all medicines, the effect of playing heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, expelling wind and removing dampness altogether.
Preferably, described Chinese medicine composition is made decoction or pill by the pharmaceutics common process.During preparation: the decocting that each crude drug of the present invention adds 600～800ml can be boiled to the decoction of 300ml be potion, or after pulverizing (fineness is thin more good more, preferred 60～80 orders), practicing honey is ball, the consumption of Mel is 1.2～1.5 times of crude drug fine powder gross weight.
Using method: each is once oral sooner or later for above-mentioned decoction or pill, potion of decoction, 6g of pill (ball is heavy); Can fully recover about 4 months.
Chinese medicine composition of the present invention has very strong specific aim to the joint type psoriasis treatment, and cure rate is up to 94%, and is difficult for recurrence with the back.
The specific embodiment
Below with specific embodiment the present invention is described in further detail, but protection scope of the present invention is not limited thereto:
Embodiment 1
Take by weighing Zaocys 20g, Scorpio 9g, Scolopendra 9g, Periostracum Cicadae 12g, Radix Rehmanniae 20g, Rhizoma Paridis 20g, Herba Hedyotidis Diffusae 20g, Radix Angelicae Sinensis 20g, Radix Salviae Miltiorrhizae 50g, Radix Paeoniae Rubra 10g, Caulis Spatholobi 45g, Radix Gentianae Macrophyllae 13g, Gamdir Vine 20g, Bombyx Batryticatus 20g, Rhizoma Et Radix Notopterygii 20g, Caulis Piperis Kadsurae 11g, Radix Glycyrrhizae 15g, Rhizoma Smilacis Glabrae 25g.The decocting that each crude drug of present embodiment is added 750ml boil to the decoction of 300ml be potion, or after being crushed to 75 orders, add the Mel of 503g, make pill.
Embodiment 2
Take by weighing Zaocys 25g, Scorpio 13g, Scolopendra 15g, Periostracum Cicadae 13g, Radix Rehmanniae 25g, Rhizoma Paridis 25g, Herba Hedyotidis Diffusae 25g, Radix Angelicae Sinensis 18g, Radix Salviae Miltiorrhizae 40g, Radix Paeoniae Rubra 13g, Caulis Spatholobi 60g, Radix Gentianae Macrophyllae 12g, Gamdir Vine 30g, Bombyx Batryticatus 15g, Rhizoma Et Radix Notopterygii 13g, Caulis Piperis Kadsurae 13g, Radix Glycyrrhizae 13g, Rhizoma Smilacis Glabrae 20g.The decocting that each crude drug of present embodiment is added 800ml boil to the decoction of 300ml be potion, or after being crushed to 80 orders, add the Mel of 582g, make pill.
Embodiment 3
Take by weighing Zaocys 15g, Scorpio 6g, Scolopendra 6g, Periostracum Cicadae 10g, Radix Rehmanniae 15g, Rhizoma Paridis 15g, Herba Hedyotidis Diffusae 15g, Radix Angelicae Sinensis 15g, Radix Salviae Miltiorrhizae 30g, Radix Paeoniae Rubra 15g, Caulis Spatholobi 30g, Radix Gentianae Macrophyllae 15g, Gamdir Vine 10g, Bombyx Batryticatus 10g, Rhizoma Et Radix Notopterygii 10g, Caulis Piperis Kadsurae 10g, Radix Glycyrrhizae 6g, Rhizoma Smilacis Glabrae 15g.The decocting that each crude drug of present embodiment is added 600ml boil to the decoction of 300ml be potion, or after being crushed to 60 orders, add the Mel of 297g, make pill.
Embodiment 4
Take by weighing Zaocys 30g, Scorpio 15g, Scolopendra 13g, Periostracum Cicadae 15g, Radix Rehmanniae 30g, Rhizoma Paridis 30g, Herba Hedyotidis Diffusae 30g, Radix Angelicae Sinensis 10g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Rubra 20g, Caulis Spatholobi 15g, Radix Gentianae Macrophyllae 10g, Gamdir Vine 15g, Bombyx Batryticatus 13g, Rhizoma Et Radix Notopterygii 15g, Caulis Piperis Kadsurae 15g, Radix Glycyrrhizae 8g, Rhizoma Smilacis Glabrae 30g.The decocting that each crude drug of present embodiment is added 680ml boil to the decoction of 300ml be potion, or after being crushed to 70 orders, add the Mel of 428g, make pill.
Clinical trial:
(1), physical data: accept patient's 83 examples altogether for medical treatment, wherein male 50 examples, women 33 examples, age reckling 6 years old, the maximum 73 years old, case is the shortest 1 year, has a surplus in the longest 10 years.
(2), efficacy assessment standard: recovery from illness: psoriasis skin lesion transference cure, the arthropathy of getting involved, pain disappear, activity freely; Effectively: psoriasis skin lesion transference cure is more than 60%, and the arthropathy of getting involved returns to normally substantially, pain obviously alleviates, and mobility significantly strengthens; Invalid: psoriasis skin lesion symptom no change, the arthropathy of getting involved, pain no change, activity is still limited.
(3), administering mode and approach: with the decoction administration of embodiment 4 preparations, each oral potion sooner or later.
(4), statistical result: 67 examples of fully recovering, effective 11 examples, invalid 5 examples, total effective rate is 94%.
Model case
Case 1 Chen, man, 32 years old.Examine in March, 2008, part palm, fingernail edge Scaling, pruritus, and the distortion of both hands articulations digitorum manus, the both hands back of the body is swollen painful, and both hands refer to bend and stretch difficulty, are diagnosed as the joint type psoriasis.Take the pill of embodiment 1 and fully recover after 3 months 20 days, follow up a case by regular visits to and do not see recurrence so far.
Case 2 Pan so-and-so, woman, 43 years old.In December, 2007 is examined, and readme was suffered from psoriasis more than 10 year, and whole body all has the erythema squama, and congestion and swelling pain appears in knee joint when examining, and can not walk when serious, and deformity appears in finger-joint, is diagnosed as the joint type psoriasis.Take the decoction of embodiment 3 and fully recover after 4 months, follow up a case by regular visits to and do not see recurrence so far.
3 pairs of cases so-and-so, man, 67 years old.Examine in November, 2006, readme suffers from arthritis and had a surplus in 20 years, often have a pain in the leg, knee plays several little red pimples, pruritus before 5 years, peeling, in this year, little pimple increases increase gradually, and spreads to the both hands elbow outside, pruritus, desquamation, through the X ray examination, show that cartilage disappears, articular surface corrodes, the joint space narrows down, soft tissue swelling, osteoporosis, dissolving or with bony ankylosis, hospital diagnosis is " a joint type psoriasis " in local county hospital, also Ceng Kaifang treatment of hospital, but poor effect.Fully recover after taking 4 first quarter moons of decoction of embodiment 4, follow up a case by regular visits to and do not see recurrence so far.
Claims (3)
1. the psoriasic Chinese medicine composition of treatment joint type is characterized in that being made by each crude drug of following portions by weight: 15～30 parts of Zaocyss, 6～15 parts of Scorpios, 6～15 parts of Scolopendras, 10～15 parts of Periostracum Cicadaes, 15～30 parts of Radix Rehmanniae, 15～30 parts of Rhizoma Paridis, 15～30 parts of Herba Hedyotidis Diffusaes, 10～20 parts of Radix Angelicae Sinensis, 15～50 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Paeoniae Rubra, 15～60 parts of Caulis Spatholobis, 10～15 parts of Radix Gentianae Macrophyllae, 10～30 parts of Ramulus Uncariae Cum Uncis, 10～20 parts of Bombyx Batryticatus, 10～20 parts of Rhizoma Et Radix Notopterygiis, 10～15 parts of Caulis Piperis Kadsuraes, 6～15 parts of Radix Glycyrrhizae, 15～30 parts of Rhizoma Smilacis Glabraes.
2. the psoriasic Chinese medicine composition of treatment joint type as claimed in claim 1, it is characterized in that: the parts by weight of described each crude drug are: 15 parts of Zaocyss, 6 parts of Scorpios, 6 parts of Scolopendras, 10 parts of Periostracum Cicadaes, 15 parts of Radix Rehmanniae, 15 parts of Rhizoma Paridis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Paeoniae Rubra, 30 parts of Caulis Spatholobis, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Bombyx Batryticatus, 10 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Caulis Piperis Kadsuraes, 6 parts of Radix Glycyrrhizae, 15 parts of Rhizoma Smilacis Glabraes.
3. the psoriasic Chinese medicine composition of treatment joint type as claimed in claim 1 or 2, it is characterized in that: described Chinese medicine composition is made decoction or pill by the pharmaceutics common process.
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| CN104826077A (en) * | 2015-05-28 | 2015-08-12 | 张家富 | TCM (traditional Chinese medicine) preparation for psoriatic arthritis and preparing method thereof |
Citations (3)
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| CN1682900A (en) * | 2005-02-22 | 2005-10-19 | 杜焕喜 | Chinese medicine preparation for treating psoriasis |
| CN1947774A (en) * | 2006-09-12 | 2007-04-18 | 陈志坚 | Traditional Chinese medicine for treating psora |
| CN101411826A (en) * | 2007-10-18 | 2009-04-22 | 天津白头山制药有限公司 | Internal-use medicament for treating psoriasis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682900A (en) * | 2005-02-22 | 2005-10-19 | 杜焕喜 | Chinese medicine preparation for treating psoriasis |
| CN1947774A (en) * | 2006-09-12 | 2007-04-18 | 陈志坚 | Traditional Chinese medicine for treating psora |
| CN101411826A (en) * | 2007-10-18 | 2009-04-22 | 天津白头山制药有限公司 | Internal-use medicament for treating psoriasis |
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| 万鹏等.吴军教授治疗银屑病经验.《四川中医》.2006,第24卷(第2期),8-9. * |
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