CN101411826A - Internal-use medicament for treating psoriasis - Google Patents

Internal-use medicament for treating psoriasis Download PDF

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CN101411826A
CN101411826A CNA2007100599272A CN200710059927A CN101411826A CN 101411826 A CN101411826 A CN 101411826A CN A2007100599272 A CNA2007100599272 A CN A2007100599272A CN 200710059927 A CN200710059927 A CN 200710059927A CN 101411826 A CN101411826 A CN 101411826A
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radix
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gram
treatment
polygoni multiflori
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张在春
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TIANJIN BAITOUSHAN PHARMACEUTICAL CO Ltd
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TIANJIN BAITOUSHAN PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to an internal medicine for treating psoriasis, which is characterized in that the formulation thereof comprises angelica, radix polygoni multiflori preparata, red sage root, spatholobus stem, zaocys dhumnade, scorpion, centipede, radix rehmanniae recen, gromwell, radix paeoniae rubra, rhizoma imperatae, pagodatree flower, cicada ecdysis, white tribulus terrestris, radix sophorae flavescentis, radix sileris, night shade, and moutan bark. The internal medicine has the following advantages: 1. the internal medicine is a pure traditional Chinese medicine composite preparation and is reasonably prepared; and 2. all the Chinese herbal medicines used by the preparation have the efficacies of clearing away heat and toxic material, promoting blood circulation and cooling blood, and preserving health and dispersing pathogenic wind, and the effective rate reaches 100 percent.

Description

The psoriasic innerlich anwenden of a kind of treatment
(1) technical field:
The present invention relates to innerlich anwenden, the psoriasic innerlich anwenden of particularly a kind of treatment
(2) background technology:
Psoriasis is in the clinical dermatosis that is considered to the comparison stubbornness, common psoriasis has arthritis type substantially, Folium Styracis Suberifoliae type and dense bleb type, its performance position is on skin, China is many for the Therapeutic Method of this kind disease at present, as boil medicine scald, smear outward, ointment, liquid medicine, sleep therapy, therapy of blood-letting, injection etc.That adopts hormone therapy abroad also has certain curative effect, but instant effect, recurs also soon, and certain side effect is arranged, the drug price virtual height, and curative effect is unsatisfactory.
(3) summary of the invention:
The object of the present invention is to provide the psoriasic innerlich anwenden of a kind of treatment, its low price, processing technique is simple, and raw material is easy to get, and has no side effect, and can cooperate medicine for external use effectively to treat psoriasis.
Technical scheme of the present invention: the psoriasic innerlich anwenden of a kind of treatment, the prescription that it is characterized in that it is: Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Zaocys, Scorpio, Scolopendra, Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Paeoniae Rubra, Rhizoma Imperatae, Flos Sophorae, Periostracum Cicadae, Fructus Atriplicis Sibiricae, Radix Sophorae Flavescentis, Radix Saposhnikoviae, Herba Solani Nigri and Cortex Moutan, its proportioning is: Radix Angelicae Sinensis 3-15 gram, Radix Polygoni Multiflori Preparata 3-15 gram, Radix Salviae Miltiorrhizae 6-30 gram, Caulis Spatholobi 6-30 gram, Zaocys 6-20 gram, Scorpio 5-15 gram, Scolopendra 0.5-5 bar, Radix Rehmanniae 10-50 gram, Radix Arnebiae (Radix Lithospermi) 6-30 gram, Radix Paeoniae Rubra 6-30 gram, Rhizoma Imperatae 10-50 gram, Flos Sophorae 10-50 gram, Periostracum Cicadae 2-10 gram, Fructus Atriplicis Sibiricae 3-12 gram, Radix Sophorae Flavescentis 3-12 gram, Radix Saposhnikoviae 3-12 gram, Herba Solani Nigri 6-30 gram, Cortex Moutan 6-25 gram.
Above-mentioned said preferential scope is: Radix Angelicae Sinensis 8-15 gram, Radix Polygoni Multiflori Preparata 8-15 gram, Radix Salviae Miltiorrhizae 10-30 gram, Caulis Spatholobi 10-30 gram, Zaocys 10-20 gram, Scorpio 10-15 gram, Scolopendra 0.5-5 bar, Radix Rehmanniae 10-50 gram, Radix Arnebiae (Radix Lithospermi) 12-30 gram, Radix Paeoniae Rubra 10-25 gram, Rhizoma Imperatae 10-50 gram, Flos Sophorae 10-50 gram, Periostracum Cicadae 2-10 gram, Fructus Atriplicis Sibiricae 3-12 gram, Radix Sophorae Flavescentis 3-12 gram, Radix Saposhnikoviae 3-12 gram, Herba Solani Nigri 10-30 gram, Cortex Moutan 10-25 gram.
Above-mentioned said preferred version is: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 8 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 18 grams, Zaocys 17 grams, Scorpio 10 grams, 1 of Scolopendra, Radix Rehmanniae 18 grams, Radix Arnebiae (Radix Lithospermi) 12 grams, Radix Paeoniae Rubra 10 grams, Rhizoma Imperatae 18 grams, Flos Sophorae 18 grams, Periostracum Cicadae 2 grams, Fructus Atriplicis Sibiricae 4 grams, Radix Sophorae Flavescentis 4 grams, Radix Saposhnikoviae 4 grams, Herba Solani Nigri 10 grams, Cortex Moutan 10 grams.
Above-mentioned said another preferred version is: Radix Angelicae Sinensis 12 grams, Radix Polygoni Multiflori Preparata 15 grams, Radix Salviae Miltiorrhizae 25 grams, Caulis Spatholobi 30 grams, Zaocys 20 grams, Scorpio 15 grams, 3 of Scolopendras, Radix Rehmanniae 50 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Radix Paeoniae Rubra 25 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 50 grams, Periostracum Cicadae 6 grams, Fructus Atriplicis Sibiricae 12 grams, Radix Sophorae Flavescentis 12 grams, Radix Saposhnikoviae 12 grams, Herba Solani Nigri 30 grams, Cortex Moutan 25 grams.
The dosage form of the psoriasic innerlich anwenden of above-mentioned said treatment can be tablet, oral solutions, electuary or capsule.
The pharmacology analysis of magistral medicines of the present invention:
1, Radix Angelicae Sinensis: Radix Angelicae Sinensis sweet in the mouth, suffering, warm in nature, return liver, the heart, spleen channel.Its function be for can nourish blood, invigorate blood circulation, enrich blood, and reducing swelling and alleviating pain again can tonic blood and growing muscle, so used always by the surgery ulcer sores.
2, Radix Polygoni Multiflori Preparata: Radix Polygoni Multiflori Preparata bitter in the mouth, sweet, puckery, warm in nature, have the effect of invigorating the liver and kidney, benefiting essence-blood, strengthening bone and muscle, black beard and hair, defying age, be mainly used in that the Liver and kidney essence and blood loses, blood deficiency and yellow complexion, have a dizzy spell diseases such as early whitening of hair, soreness of the waist and knees.
3, Radix Salviae Miltiorrhizae: bitter in the mouth, cold in nature, have promoting blood circulation and cooling blood, stasis-dispelling and pain-killing, the effect of the relieving restlessness of calming the nerves, contain TANSHINONES, iso tanshinone, different cryptotanshinone, vitamin E, be applicable to blood circulation promoting and blood stasis dispelling, deficiency of YIN noxious dampness, sore, skin eczema goiter, poison, damp and hotly disease such as flee.
4, Caulis Spatholobi: nature and flavor hardship, sweet, temperature is returned Liver Channel, contains milletol, irony, campesterol, stigmasterol and sitoesterol; Staphylococcus aureus there is inhibitory action, antiinflammatory action is arranged; Be applicable to that promoting the circulation of blood enriches blood regulating menstruation, relaxing muscles and tendons and activating QI and blood in the collateral; Cure mainly month through uncomfortable, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
5, Zaocys: nature and flavor are sweet, and are flat, return Liver Channel, contain protein and fat; Be applicable to dispelling wind and removing obstruction in the collateral, arresting convulsion relieves the pain.Cure mainly rheumatoid arthritis stubborn, numbness contracture, apoplexy deviation of the eye and mouth, hemiplegia, tic spasm, tetanus disease, leprosy scabies, scrofula malignant boil.
6, Scorpio: it is salty, hot, flat, poisonous, goes into Liver Channel; Have dispel the wind, the function of arresting convulsion, spasmolytic; Cure mainly facial hemiparalysis, rheumatism paralysis, spasm tic, tetanus, malignant boil toxic swelling diseases such as (externals); Scorpio contains protein, several amino acids after testing; also contain trimethylamine, betanin, taurine, palmitic acid, stearic acid, cholesterol, lecithin, ammonium salt, scorpion acid etc.; also contain charybdotoxin; the polypeptides matter that system is made up of more than 60 aminoacid etc.; be a kind of toxic protein, similar to the neural malicious class of Serpentis and poisonous insect.
7, Scolopendra: nature and flavor suffering, temperature, poisonous, return Liver Channel; Effect is applied to endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Cure mainly infantile convulsion, spasm is twitched, apoplexy deviated mouth, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, sore swollen toxin, scrofula tuberculosis, venom etc.; Scolopendra all has antagonism to the mice convulsion that pentetrazole, pure nicotine and strychnine etc. cause; Scolopendra water logging agent has in various degree inhibitory action to tubercule bacillus and various skin fungus; Scolopendra Hirudo injection has inhibitory action to tumor cell, and monokaryon-phagocytic function is had potentiation.
8, Radix Rehmanniae: nature and flavor are sweet, bitter, and are cold; GUIXIN, liver, lung meridian; Contain β-sitoesterol, rehmanin, mannitol, glucose, alkaloid, irony, vitamin A etc.; Radix Rehmanniae has effects such as certain heart tonifying, diuresis, rising blood pressure, blood sugar lowering; The extract of Radix Rehmanniae can promote solidifying of blood, and the oral fresh rehmannia charcoal of mice can shorten the bleeding time, and the Radix Rehmanniae decoct also has the liver protecting, prevents the effect that hepatic glycogen reduces, and certain Antiradiation injury effect is arranged, and multiple fungi growth is had inhibitory action; Be applicable to clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting cures mainly YIN damaged by pathogenic heat, the crimson tongue excessive thirst, and interior-heat caused by deficiency of YIN, night fever abating at dawn, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, hematemesis and epistaxis, maculopapulae due to toxic heat.
9, Radix Arnebiae (Radix Lithospermi): nature and flavor are sweet, cold, GUIXIN, Liver Channel; Contain Acetyl-shikonin Acetylshikonin, shikonin etc.; Its decoct to heart for low dose of excited, be inhibitory action in a large number; Demulcent refrigeration function is arranged, pathogenic microorganisms such as golden yellow coccus, escherichia coli, influenza virus are had inhibitory action; Contraceptive efficacy is arranged; Radix Arnebiae (Radix Lithospermi) also has antiinflammatory action, and chorionic epithelioma and malignant mole are had certain therapeutical effect; Be applicable to removing heat from blood and promoting blood circulation, the detoxifcation rash cures mainly maculae caused by violent heat pathogen, and measles is purple dark, and rash goes out not smooth, ulcer sores, eczema pudendal pruritus, burn due to hot liquid or fire.
10, Radix Paeoniae Rubra: the nature and flavor hardship, be slightly cold, return Liver Channel, contain peoniflorin, paeonol, peonin, benzoic acid, tannin, resin, volatile oil, β-sitoesterol, this terpenoid etc.; Pharmacological action energy coronary artery dilator improves hypoxia-bearing capability, and anti-platelet aggregation is arranged, and antithrombotic forms, anti-experimental character myocardial ischemia, microcirculation improvement and the effect of reduction portal hypertension.Spasmolysis is arranged, and peoniflorin has calmness, antiinflammatory, analgesia, analgesic and convulsion, antiulcer and hypotensive effect, and multiple pathogenic microorganism is had in various degree inhibitory action; Effect is used clearing away heat and cooling blood, and eliminating stasis to stop pain cures mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , mass in the abdomen stomachache, tumbling down damage, carbuncle skin infection.
11, Rhizoma Imperatae: another name Rhizoma Imperatae, Huang Mao, Cymbidium ensifolium (L.) Sw. root, silk Rhizoma Imperatae, sweet, Rhizoma Imperatae, cold in nature, sweet in the mouth, chemical constituent contains arundoin (arundoin), Cylindrin (cylindrin), fernenol (fernenol) and simiarenol (simiarenol) etc., and contains citric acid, malic acid, oxalic acid, sucrose, fructose, glucose etc.; Function cures mainly cooling blood for hemostasis, clearing away heat and promoting diuresis.Be used for heat in blood haematemesis, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria, acute nephritis edema.
12, Flos Sophorae: Flos Sophorae nature and flavor hardship is slightly cold, and goes into liver, large intestine channel.Contain globulariacitrin, betulin, sophoradiol, glucose, glucuronic acid, Flos Sophorae Immaturus first element, Flos Sophorae Immaturus second element, Flos Sophorae Immaturus third element, tannin and retinoid material; Have cooling blood for hemostasis, the effect of the diuresis of drying, can keep the normal resistivity of blood capillary, bring high blood pressure down, and be used for prevention of stroke, the effect that also has simultaneously heat clearing away invigorating middle warmer, detoxifcation to moisturize, " Japan hanako materia medica " say it can " control five hemorrhoid, pained; conjunctival congestion, kill alvus worm and heat, ripple skin wind.
13, Periostracum Cicadae: nature and flavor are sweet, cold, return lung, Liver Channel; Contain a large amount of chitins and protein, aminoacid, organic acid etc.; Has anticonvulsant action, its medicated wine can make the average survival period of experimental tetanus rabbit prolong, can alleviate the established tetanus of rabbit and faint from fear, Periostracum Cicadae can be resisted the mice convulsion death that central stimulantss such as strychnine, cocaine, nicotinamide cause, anticonvulsant action Periostracum Cicadae body is strong than cephalopodium; Periostracum Cicadae can suppress the spontaneous activity of mice, can work in coordination with the anesthetic action of ciclobarbital soluble and has showed sedation; Periostracum Cicadae still has refrigeration function, and wherein the Periostracum Cicadae cephalopodium is strong than the refrigeration function of body portion; Its effect is used and is dispelling wind and heat pathogens, rash pain relieving, improving acuity of vision and removing nebula, relieving convulsion; Cure mainly anemopyretic cold, fever and headache, pharyngalgia, measles without adequate eruption, rubella eczema, skin pruritus, conjunctival congestion and swelling pain, pterygium, infantile convulsion night cry, diseases such as tetanus.
14, Fructus Atriplicis Sibiricae: nature and flavor suffering, hardship, tepor is gone into Liver Channel, has the effect of pancake liver-yang, can be soothing the liver, dispel the wind, make eye bright; Clinically be used for diseases such as excessive rising of liver-YANG, dizziness and blurred vision, the many tears of conjunctival congestion, rubella pruritus,, the effect of dispelling wind for relieving itching arranged the health pruritus.
15, Radix Sophorae Flavescentis: nature and flavor bitter cold, bitter in the mouth, the effect of heat clearing and damp drying, killing parasites for relieving itching are arranged, dispeling the wind; Cure mainly heat clearing and damp drying, the parasite killing diuresis is used for hematodiarrhoea, has blood in stool, card such as jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, damp-heat accumulation; External treatment trichomonal vaginitis, because of its bitter in the mouth cold in nature, later age is many from the eliminating evil argument of the dampness of relieving inflammation or internal heat, and " book on Chinese herbal medicine justice " spells out the nature and flavor characteristics of Radix Sophorae Flavescentis: " in big bitter Great Cold, bring down a fever to fall and let out; cleanse wet fire; its effect and Radix Scutellariae, Rhizoma Coptidis, Radix Gentianae are all close, and the hardship of Radix Sophorae Flavescentis more, and it is dry strong especially; so can kill the damp and hot worm that gives birth to, than a kind of reed mentioned in ancient books, even the strength benefit is strong.
16, Radix Saposhnikoviae: nature and flavor suffering, sweet, tepor, return bladder, liver, spleen channel, main component is mannitol, volatilization wet goods.The volatile oil master contains acetaldehyde, acetic acid, enanthaldehyde, sad, aldehyde C-9, acetic acid, hexadecane, β-farnesene, sad, α-curcumene, β-elemene, n-heptadecane, n-octadecane, ethyl palmitate; Expelling pathogenic wind from the body surface is arranged, dehumidifying, the effect of relieving convulsion; Main pharmacological: to the artificial fever rabbit, per os gives Radix Saposhnikoviae decoct or preserved material, and the trivial solution heat effect is arranged; Mouse gavaging Radix Saposhnikoviae 50% alcohol leaching liquid can obviously improve the threshold of pain; Fresh Radix Saposhnikoviae press liquor has certain antibacterial action in vitro tests to bacillus pyocyaneus and staphylococcus aureus; Be used for headache due to common cold, migratory arthralgia pain, rubella pruritus, tetanus.
17, Herba Solani Nigri: nature and flavor hardship, little sweet, sliding, cold, slightly poisonous, the effect of heat-clearing and toxic substances removing and eliminating stagnation is arranged, be used for heat-clearing and toxic substances removing, eliminating stagnation, diuresis, laryngopharynx swelling and pain, diseases such as carbuncle furunculosis, this product on probation clinically now has certain curative effect as keeping away tired anthypnotic.
18, Cortex Moutan: nature and flavor are arduous, and the heart, liver, kidney channel are gone in cold, concoct medicine and go into lung meridian.Root contains paeonol, paeonolide, paeonolide, paeoniflorin, still contains volatile oil 0.15~0.4% and plant sterol etc.; Function cures mainly heat clearing away, removing heat from blood, and blood, repercussive; Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion is told, is defeated in battle, is had blood in stool, the hectic fever due to YIN-deficiency consumptive fever, and amenorrhea , mass in the abdomen, carbuncle and ulcer is pounced on damage; " Japan hanako materia medica " record " remove pathogen, please color, the natural fibre line of meat blood vessels of being open to the custom, evacuation of pus, logical menstruation disappears and pounces on the damage blood stasis, and reuniting the fractured tendons and bones removes migratory arthralgia; " the southern regions of the Yunnan Province book on Chinese herbal medicine " record " removing blood stasis, row (blood), the disease of the mass in the abdomen that disappears, the heat of dehematize branch; Paeonol has inhibitory action to rat hindlimb foot/edema, and can reduce vascular permeability, and the Cortex Moutan immersion has strong antibacterial action, 10 kinds of dermatophytess such as rust microspore bacterium is also had certain inhibitory action in vitro.
Clinical case analysis of the present invention: the patient who receives treatment (mainly comprising erythroderma type psoriatic), add up to 120, wherein the male patient is 78, accounting for 65%. female patients is 42, accounts for 35%; Wherein 8-15 year patient is 15, accounts for 12.5%; 105 of 20-68 year patients account for 87.5.%.
Model case is introduced:
Case 1: Wang man 26 years old
The main suit: the whole skin desquamation, congestion, black and blue, autumn and winter season especially, sx, bloodstained all over the thick squama of body, seek the tens of families of doctor and all just control and take effect end-of-dose failure.
Diagnosis: erythroderma type psoriasis
Handle: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 10 grams, Radix Salviae Miltiorrhizae 15 grams, Caulis Spatholobi 15 grams, Zaocys 10 grams, Scorpio 12 grams, 3 of Scolopendras, Radix Rehmanniae 40 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Radix Paeoniae Rubra 20 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 30 grams, Periostracum Cicadae 8 grams, Fructus Atriplicis Sibiricae 8 grams, Radix Sophorae Flavescentis 5 grams, Radix Saposhnikoviae 6 grams, Herba Solani Nigri 15 grams, Cortex Moutan 25 grams.
Further consultation: two courses of treatment of external combination medicine in taking, all transference cures, the skin smooth exquisiteness is taken the interior curative of use of a course of treatment again, is used for consolidation, does not see recurrence in 5 years so far.
Case 2: opened the birch woman 31 years old
The main suit: the whole body desquamation, congestion is black and blue.Especially autumn and winter sx, bloodstained all over the thick tinea of body, once used a lot of Drug therapys such as enlightening silver, all do not have positive effect.
Diagnosis: erythroderma type psoriasis
Handle: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 10 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 15 grams, Zaocys 15 grams, Scorpio 10 grams, 2 of Scolopendras, Radix Rehmanniae 40 grams, Radix Arnebiae (Radix Lithospermi) 12 grams, Radix Paeoniae Rubra 25 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 30 grams, Periostracum Cicadae 7 grams, Fructus Atriplicis Sibiricae 6 grams, Radix Sophorae Flavescentis 6 grams, Radix Saposhnikoviae 8 grams, Herba Solani Nigri 20 grams, Cortex Moutan 20 grams.
Further consultation: after external combination medicine was treated 2 courses of treatment in taking, whole body recovered normally substantially, after the later stage after treatment, and very fast recovery from illness, skin smooth is beautiful, so far not recurrence in 5 years.
Case 3: Liu so-and-so man 55 years old
The main suit: the beginning whole body grew full of stains or spots of skin lesion everywhere in 90 years, and skin is dry and astringent, and large stretch of erythema covering silver bits appear in whole body before 2 years, increase the weight of autumn and winter agonizing especially.
Diagnosis: erythroderma type psoriasis
Handle: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 13 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 30 grams, Zaocys 15 grams, Scorpio 12 grams, 4 of Scolopendras, Radix Rehmanniae 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Radix Paeoniae Rubra 25 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 40 grams, Periostracum Cicadae 9 grams, Fructus Atriplicis Sibiricae 12 grams, Radix Sophorae Flavescentis 10 grams, Radix Saposhnikoviae 8 grams, Herba Solani Nigri 25 grams, Cortex Moutan 15 grams.
Further consultation: use in the treatment psoriasis external combination medicine after 20 days squama disappear, disappear with the whole squamas of extremity and trunk after two courses of treatment, skin recovers normally fully, the skin smoothness did not recur in 3 years so far.
Case 4, woman Feng 35 years old
The main suit: three months pharyngeal discomforts of cause, and itch all over is arranged, the little Folium Styracis Suberifoliae that whole body occurs is examined, and does not arouse attention at that time, and skin was examined area and was increased surperficial white scales gradually afterwards. through not good enough with Western medicine and medicine for external use therapeutic effect.
Diagnosis: acute psoriasis
Handle: Radix Angelicae Sinensis 15 grams, Radix Polygoni Multiflori Preparata 15 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 25 grams, Zaocys 20 grams, Scorpio 13 grams, 5 of Scolopendras, Radix Rehmanniae 50 grams, Radix Arnebiae (Radix Lithospermi) 12 grams, Radix Paeoniae Rubra 25 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 30 grams, Periostracum Cicadae 10 grams, Fructus Atriplicis Sibiricae 10 grams, Radix Sophorae Flavescentis 10 grams, Radix Saposhnikoviae 8 grams, Herba Solani Nigri 30 grams, Cortex Moutan 25 grams.
Further consultation: take effect in the week, skin lesion begins to calm down attenuation, color is thin out, and the lower limb skin lesion comes off, and right upper extremity part skin lesion disappears from the edge, residual hypopigmentation, the lower limb skin lesion all comes off after 3 weeks, and it is normal to walk, and cures through three courses of treatment, can take part in the work, consolidate after two courses of treatment treatment afterwards and do not have recurrence in 5 years so far.
Case 5: Zhao man
The main suit: suffered from psoriasis 32 years, head, back, chest, extremity are long more many more, joins together, and whole skin drying, desquamation, bloodstained, especially season in spring and autumn, the state of an illness oncoming force is more severe.
Diagnosis: erythroderma type psoriasis
Handle: Radix Angelicae Sinensis 15 grams, Radix Polygoni Multiflori Preparata 10 grams, Radix Salviae Miltiorrhizae 25 grams, Caulis Spatholobi 25 grams, Zaocys 20 grams, Scorpio 13 grams, 1 of Scolopendra, Radix Rehmanniae 50 grams, Radix Arnebiae (Radix Lithospermi) 18 grams, Radix Paeoniae Rubra 20 grams, Rhizoma Imperatae 30 grams, Flos Sophorae 50 grams, Periostracum Cicadae 6 grams, Fructus Atriplicis Sibiricae 5 grams, Radix Sophorae Flavescentis 12 grams, Radix Saposhnikoviae 8 grams, Herba Solani Nigri 15 grams, Cortex Moutan 20 grams.
Further consultation: take medicine after half course of treatment, the state of an illness has greatly improved, the scurf attenuation, erythra begins to have disappeared, after recover normal after taking the medicines of 2 courses of treatment again, do not have recurrence in 5 years so far.
Case 6: certain man of week 46 years old
The main suit: the whole body desquamation, black and blue, once to see the doctor for treatment everywhere, the state of an illness is shown effect repeatedly, is difficult to cure.
Diagnosis: erythroderma type psoriasis
Handle: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 8 grams, Radix Salviae Miltiorrhizae 12 grams, Caulis Spatholobi 15 grams, Zaocys 20 grams, Scorpio 15 grams, 4 of Scolopendras, Radix Rehmanniae 50 grams, Radix Arnebiae (Radix Lithospermi) 18 grams, Radix Paeoniae Rubra 20 grams, Rhizoma Imperatae 30 grams, Flos Sophorae 30 grams, Periostracum Cicadae 5 grams, Fructus Atriplicis Sibiricae 12 grams, Radix Sophorae Flavescentis 10 grams, Radix Saposhnikoviae 12 grams, Herba Solani Nigri 30 grams, Cortex Moutan 10 grams.
Further consultation: whole body recovers normally substantially after taking three course of treatment medicines, and after the later stage after treatment, fully recovering did not very soon have recurrence in 5 years.
Conclusion: 120 patients take this medicine after 2 courses of treatment course of treatment to 4 the psoriasis symptom disappear, it is normal that skin recovers, effective percentage reaches 100%; With this combination medicine treatment 30-70 days, the symptom complete obiteration of skin affected part, and recover normal, the patient that 1-5 does not recur is 119 people, accounts for 99% of total number of persons; Carry out according to the regulation of present national curing psoriasis standard, promptly any medicine or therapy are as long as the psoriasis symptom of human body skin disappears in treatment one month to four months, and it is normal that skin recovers, and 1-5 not the recidivist for curing.
The treatment of the present invention course of treatment and administrated method: be one month treatment course of treatment of this medicine; Administrated method is to obey every day three times, and each 3 grams (no matter be tablet, decoction, electuary or capsule, the active component in its 3 gram is identical).
Superiority of the present invention is: 1, be the rational pure Chinese medicine composition preparation of a kind of preparation; 2, the selected Chinese herbal medicine of formulation components all has the effect that heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation, health preserving dispel the wind.
(4) specific embodiment:
Manufacture process below in conjunction with this medicine provides embodiments of the invention, is used for further specifying technical solution.
Embodiment 1: make the oral medicine liquor with 160 kilograms of raw materials.Raw material consists of Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Zaocys, Scorpio, Scolopendra, Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Paeoniae Rubra, Rhizoma Imperatae.Raw material prepares and is 4 kilograms of Radix Angelicae Sinensis, 1 kilogram of Radix Polygoni Multiflori Preparata, 8 kilograms of Radix Salviae Miltiorrhizaes, 18 kilograms of Caulis Spatholobis, 17 kilograms of Zaocyss, 5 kilograms of Scorpios, 1 kilogram of Scolopendra, 18 kilograms of Radix Rehmanniae, 8 kilograms of Radix Arnebiae (Radix Lithospermi)s, 8 kilograms of Radix Paeoniae Rubra, 18 kilograms of Rhizoma Imperataes.Preparation method will be injected suitable quantity of water for 18 flavor medicines are put into the container of boiling medicine in the container, decocted 3 times each 30-40 minute, gets inferior decoction filtrate, mixes with Chinese medicine then, makes it be concentrated to 80 kilograms, adds an amount of additive, to regulate taste, sterile filling of bottles with.
Embodiment 2; Make the capsule-type medicine with 514 kilograms of raw materials.Raw material consists of Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Zaocys, Scorpio, Scolopendra, Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Paeoniae Rubra, Rhizoma Imperatae, Flos Sophorae, Periostracum Cicadae, Fructus Atriplicis Sibiricae, Radix Sophorae Flavescentis, Radix Saposhnikoviae, Herba Solani Nigri, Cortex Moutan.Raw material prepares and is 12 kilograms of Radix Angelicae Sinensis, 15 kilograms of Radix Polygoni Multiflori Preparata, 25 kilograms of Radix Salviae Miltiorrhizaes, 50 kilograms of Caulis Spatholobis, 20 kilograms of Zaocyss, 15 kilograms of Scorpios, 15 kilograms of Scolopendras, 50 kilograms of Radix Rehmanniae, 25 kilograms of Radix Arnebiae (Radix Lithospermi)s, 25 kilograms of Radix Paeoniae Rubra, 50 kilograms of Rhizoma Imperataes.50 kilograms in Flos Sophorae, 6 kilograms of Periostracum Cicadaes, 12 kilograms of Fructus Atriplicis Sibiricaees, 12 kilograms of Radix Sophorae Flavescentiss, 12 kilograms of Radix Saposhnikoviaes, 30 kilograms of Herba Solani Nigris, 25 kilograms of Cortex Moutans.
Preparation method will be injected suitable quantity of water for 18 flavor medicines are put into the container of boiling medicine in the container, decocted 3 times each 30-40 minute, gets inferior decoction filtrate, mixes with medical starch then, with its oven dry, makes powdery and sterilization.By encapsulated pre-packaging process powdered drug is incapsulated and to form capsule in the shell, and be one to pack by 100 of every bags.
Compare embodiment 2 processing technique complexity, but taking convenience with embodiment 1.
In like manner, the technical solution that provides according to the present invention, it is identical with above embodiment to provide each constituent content, but medicament is a tablet, the embodiment of honeyed pill, or the identical or different embodiment of the different pharmaceutically dosage forms of individual constituent content.

Claims (5)

1, the psoriasic innerlich anwenden of a kind of treatment, the prescription that it is characterized in that it is: Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Zaocys, Scorpio, Scolopendra, Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Paeoniae Rubra, Rhizoma Imperatae, Flos Sophorae, Periostracum Cicadae, Fructus Atriplicis Sibiricae, Radix Sophorae Flavescentis, Radix Saposhnikoviae, Herba Solani Nigri and Cortex Moutan, its proportioning is: Radix Angelicae Sinensis 3-15 gram, Radix Polygoni Multiflori Preparata 3-15 gram, Radix Salviae Miltiorrhizae 6-30 gram, Caulis Spatholobi 6-30 gram, Zaocys 6-20 gram, Scorpio 5-15 gram, Scolopendra 0.5-5 bar, Radix Rehmanniae 10-50 gram, Radix Arnebiae (Radix Lithospermi) 6-30 gram, Radix Paeoniae Rubra 6-30 gram, Rhizoma Imperatae 10-50 gram, Flos Sophorae 10-50 gram, Periostracum Cicadae 2-10 gram, Fructus Atriplicis Sibiricae 3-12 gram, Radix Sophorae Flavescentis 3-12 gram, Radix Saposhnikoviae 3-12 gram, Herba Solani Nigri 6-30 gram, Cortex Moutan 6-25 gram.
2, according to the psoriasic innerlich anwenden of the said a kind of treatment of claim 1, it is characterized in that said preferential scope is: Radix Angelicae Sinensis 8-15 gram, Radix Polygoni Multiflori Preparata 8-15 gram, Radix Salviae Miltiorrhizae 10-30 gram, Caulis Spatholobi 10-30 gram, Zaocys 10-20 gram, Scorpio 10-15 gram, Scolopendra 0.5-5 bar, Radix Rehmanniae 10-50 gram, Radix Arnebiae (Radix Lithospermi) 12-30 gram, Radix Paeoniae Rubra 10-25 gram, Rhizoma Imperatae 10-50 gram, Flos Sophorae 10-50 gram, Periostracum Cicadae 2-10 gram, Fructus Atriplicis Sibiricae 3-12 gram, Radix Sophorae Flavescentis 3-12 gram, Radix Saposhnikoviae 3-12 gram, Herba Solani Nigri 10-30 gram, Cortex Moutan 10-25 gram.
3, according to the psoriasic innerlich anwenden of the said a kind of treatment of claim 1, it is characterized in that said preferred version is: Radix Angelicae Sinensis 8 grams, Radix Polygoni Multiflori Preparata 8 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 18 grams, Zaocys 17 grams, Scorpio 10 grams, 1 of Scolopendra, Radix Rehmanniae 18 grams, Radix Arnebiae (Radix Lithospermi) 12 grams, Radix Paeoniae Rubra 10 grams, Rhizoma Imperatae 18 grams, Flos Sophorae 18 grams, Periostracum Cicadae 2 grams, Fructus Atriplicis Sibiricae 4 grams, Radix Sophorae Flavescentis 4 grams, Radix Saposhnikoviae 4 grams, Herba Solani Nigri 10 grams, Cortex Moutan 10 grams.
4, according to the psoriasic innerlich anwenden of the said a kind of treatment of claim 1, it is characterized in that said another preferred version is: Radix Angelicae Sinensis 12 grams, Radix Polygoni Multiflori Preparata 15 grams, Radix Salviae Miltiorrhizae 25 grams, Caulis Spatholobi 30 grams, Zaocys 20 grams, Scorpio 15 grams, 3 of Scolopendras, Radix Rehmanniae 50 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Radix Paeoniae Rubra 25 grams, Rhizoma Imperatae 50 grams, Flos Sophorae 50 grams, Periostracum Cicadae 6 grams, Fructus Atriplicis Sibiricae 12 grams, Radix Sophorae Flavescentis 12 grams, Radix Saposhnikoviae 12 grams, Herba Solani Nigri 30 grams, Cortex Moutan 25 grams.
5, according to the psoriasic innerlich anwenden of the said a kind of treatment of claim 1, it is characterized in that the dosage form of the psoriasic innerlich anwenden of said treatment can be tablet, oral solutions, electuary or capsule.
CNA2007100599272A 2007-10-18 2007-10-18 Internal-use medicament for treating psoriasis Pending CN101411826A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058716A (en) * 2010-12-25 2011-05-18 马建国 Tincture for treating circumscribed neuro dermatitis and preparation method thereof
CN101612293B (en) * 2009-07-30 2011-05-25 周大红 Traditional Chinese medicine composition for treating joint type psoriasis
CN102343052A (en) * 2011-10-12 2012-02-08 董洪海 Traditional Chinese medicine for psoriasis
CN103830612A (en) * 2014-03-21 2014-06-04 赵世明 Traditional Chinese medicine composition for treating tinea manus and tinea pedis
CN103860743A (en) * 2013-04-06 2014-06-18 张爱霞 Traditional Chinese medicine composite for treating psoriasis
CN104116965A (en) * 2014-07-15 2014-10-29 太仓思瑞生物科技有限公司 Traditional Chinese medicine preparation for treating scaly foot and hand fungal infection
CN104873669A (en) * 2015-06-16 2015-09-02 刘哲思 Chinese medicinal composition powder and ointment for treating psoriasis
CN104984257A (en) * 2015-07-30 2015-10-21 马丽洁 Chinese patent medicine oral-administration pills for treating psoriasis

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612293B (en) * 2009-07-30 2011-05-25 周大红 Traditional Chinese medicine composition for treating joint type psoriasis
CN102058716A (en) * 2010-12-25 2011-05-18 马建国 Tincture for treating circumscribed neuro dermatitis and preparation method thereof
CN102058716B (en) * 2010-12-25 2012-07-11 马建国 Tincture for treating circumscribed neuro dermatitis and preparation method thereof
CN102343052A (en) * 2011-10-12 2012-02-08 董洪海 Traditional Chinese medicine for psoriasis
CN103860743A (en) * 2013-04-06 2014-06-18 张爱霞 Traditional Chinese medicine composite for treating psoriasis
CN103830612A (en) * 2014-03-21 2014-06-04 赵世明 Traditional Chinese medicine composition for treating tinea manus and tinea pedis
CN104116965A (en) * 2014-07-15 2014-10-29 太仓思瑞生物科技有限公司 Traditional Chinese medicine preparation for treating scaly foot and hand fungal infection
CN104873669A (en) * 2015-06-16 2015-09-02 刘哲思 Chinese medicinal composition powder and ointment for treating psoriasis
CN104984257A (en) * 2015-07-30 2015-10-21 马丽洁 Chinese patent medicine oral-administration pills for treating psoriasis

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