CN101588792B - 纳米乳剂 - Google Patents

纳米乳剂 Download PDF

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Publication number
CN101588792B
CN101588792B CN2007800474699A CN200780047469A CN101588792B CN 101588792 B CN101588792 B CN 101588792B CN 2007800474699 A CN2007800474699 A CN 2007800474699A CN 200780047469 A CN200780047469 A CN 200780047469A CN 101588792 B CN101588792 B CN 101588792B
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nanoemulsion
composition
weight
aminolevulinic acid
active agent
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Chinese (zh)
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CN101588792A (zh
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M·福格特罗卡
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Biofrontera Bioscience GmbH
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Biofrontera Bioscience GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/21Emulsions characterized by droplet sizes below 1 micron
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2007800474699A 2006-12-22 2007-12-21 纳米乳剂 Active CN101588792B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06026698A EP1938801A1 (en) 2006-12-22 2006-12-22 Nanoemulsion
EP06026698.8 2006-12-22
PCT/EP2007/011404 WO2008077641A1 (en) 2006-12-22 2007-12-21 Nanoemulsion

Publications (2)

Publication Number Publication Date
CN101588792A CN101588792A (zh) 2009-11-25
CN101588792B true CN101588792B (zh) 2012-03-21

Family

ID=38042639

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800474699A Active CN101588792B (zh) 2006-12-22 2007-12-21 纳米乳剂

Country Status (18)

Country Link
US (2) US11540981B2 (enExample)
EP (2) EP1938801A1 (enExample)
JP (1) JP5558827B2 (enExample)
CN (1) CN101588792B (enExample)
AR (1) AR064659A1 (enExample)
AU (1) AU2007338323B2 (enExample)
BR (1) BRPI0720853A2 (enExample)
CA (1) CA2670715C (enExample)
CL (1) CL2007003730A1 (enExample)
ES (1) ES2602107T3 (enExample)
IL (1) IL198934A (enExample)
MX (1) MX2009006088A (enExample)
NZ (1) NZ577061A (enExample)
RU (1) RU2491917C2 (enExample)
UA (1) UA101471C2 (enExample)
UY (1) UY30833A1 (enExample)
WO (1) WO2008077641A1 (enExample)
ZA (1) ZA200903468B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012502B2 (en) * 2010-09-14 2015-04-21 Sbi Pharmaceuticals Co., Ltd. Cancer heat therapy-enhancing agent

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
JP2010528981A (ja) 2006-12-01 2010-08-26 アンテリオス, インコーポレイテッド 両親媒性実体ナノ粒子
SG179457A1 (en) 2006-12-01 2012-04-27 Anterios Inc Peptide nanoparticles and uses therefor
EP1938801A1 (en) * 2006-12-22 2008-07-02 Biofrontera Bioscience GmbH Nanoemulsion
KR20100050443A (ko) 2007-05-31 2010-05-13 안테리오스, 인코퍼레이티드 핵산 나노입자 및 이의 용도
JP2010143848A (ja) * 2008-12-18 2010-07-01 Kao Corp 化粧料
CN101874795A (zh) * 2009-04-28 2010-11-03 上海复旦张江生物医药股份有限公司 5-氨基酮戊酸在制备治疗hpv病毒感染的药物的用途
EP2467170A4 (en) * 2009-08-21 2013-05-29 Targeted Delivery Technologies Ltd vesicle
WO2011103510A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha ester emulsions
US20110206741A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation DHA Triglyceride Emulsions
WO2011103512A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha free fatty acid emulsions
DE202010004750U1 (de) 2010-04-09 2011-10-11 Biofrontera Bioscience Gmbh Pharmazeutische oder/und kosmetische Zusammensetzung zur Behandlung der Haut
KR20130028967A (ko) * 2010-06-23 2013-03-20 브라잇사이드 이노베이션스 인크. 레시틴 캐리어 베시클 및 이의 제조 방법
BRPI1002486B1 (pt) 2010-07-22 2017-07-18 Evidence Soluções Farmacêuticas Ltda Epp Stabilized topical composition and process of obtaining composition stable topic
JP2012051823A (ja) * 2010-08-31 2012-03-15 Fujifilm Corp 難容性薬物含有水中油型乳化組成物及びその製造方法
PH12013500783A1 (en) * 2010-10-21 2022-03-30 Cadila Healthcare Ltd Topical pharmaceutical compositions containing nanodroplets for the treatment of psoriasis
US9789123B2 (en) * 2010-10-21 2017-10-17 Cadila Healthcare Limited Topical pharmaceutical compositions containing nanodroplets for the treatment of psoriasis
US9987226B2 (en) 2010-12-10 2018-06-05 Ns Technologies Pty Ltd Methods for forming miniemulsions and use thereof for delivering bioactive agents
CN103270168A (zh) 2010-12-24 2013-08-28 爱科来株式会社 癌细胞的检测方法
DE102010056192A1 (de) 2010-12-28 2012-06-28 Gabriele Blume Kolloidales Trägersystem mit penetrierenden Eigenschaften zum Einschließen lipophiler Wirkstoffe und Öle für die topische Anwendung
KR20240119180A (ko) * 2011-01-24 2024-08-06 안테리오스, 인코퍼레이티드 나노입자 조성물, 이의 제형, 및 그의 용도
CN109464393A (zh) * 2011-01-24 2019-03-15 安特里奥公司 纳米颗粒组合物
FR2977801B1 (fr) * 2011-07-11 2013-08-16 Fabre Pierre Dermo Cosmetique Dispositif et procede pour la sterilisation a ultra-haute temperature d'une emulsion, notamment dermo-cosmetique, instable a la temperature de sterilisation
DK2804587T3 (da) 2012-01-19 2019-08-12 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Formulering og fremgangsmåde til øgning af lægemidlers biotilgængelighed
CN102600178A (zh) * 2012-03-08 2012-07-25 西北农林科技大学 一种复方盐酸布替萘芬纳米乳及其制备方法
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
US9668974B2 (en) 2012-05-10 2017-06-06 Painreform Ltd. Depot formulations of a local anesthetic and methods for preparation thereof
GB201208409D0 (en) * 2012-05-14 2012-06-27 Sequessome Technology Holdings Ltd Vesicular formulations, kits and uses
JP6112498B2 (ja) * 2012-07-20 2017-04-12 株式会社 M Labs 防腐剤・界面活性剤フリーの化粧品原料液、化粧品及び化粧品原料液の調製法
US10137085B2 (en) 2014-03-19 2018-11-27 Nano And Advanced Materials Institute Limited Nanoemulsion for transdermal delivery and method of making the same
WO2015155703A2 (en) 2014-04-09 2015-10-15 Nanoceutica Laboratories Pvt. Ltd Composition and method of producing nanoformulation of water insoluble bioactives in aqueous base
WO2016128858A1 (en) * 2015-02-11 2016-08-18 Towhidi Armin Extender for cryopreservation of bovine sperm
WO2016182926A1 (en) * 2015-05-08 2016-11-17 Affinsci Inc. Preparation of nanoemulsions
PE20180038A1 (es) 2015-05-21 2018-01-09 Glaxosmithkline Ip Dev Ltd Composiciones farmaceuticas topicas
US11617724B2 (en) 2015-05-21 2023-04-04 Dermavant Sciences GmbH Topical pharmaceutical compositions
EP3316856B1 (en) 2015-06-30 2021-04-07 Sequessome Technology Holdings Limited Blended formulations
PL3362145T3 (pl) 2015-10-15 2021-07-19 Dusa Pharmaceuticals, Inc. Regulowany oświetlacz do terapii fotodynamicznej i diagnostyki
US10603508B2 (en) 2015-10-15 2020-03-31 Dusa Pharmaceuticals, Inc. Adjustable illuminators and methods for photodynamic therapy and diagnosis
GB201522398D0 (en) * 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN105997875B (zh) * 2016-07-19 2019-05-21 重庆医科大学 一种明显提高难溶性药物生物利用度的油包水型纳米乳及其制备方法
GB2546128A (en) * 2016-09-28 2017-07-12 Photocure Asa Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same
BR112019010131A2 (pt) 2016-11-21 2019-10-08 Eirion Therapeutics, Inc. entrega transdérmica de agentes grandes
EP3655035A4 (en) * 2017-07-17 2021-04-14 Andrea Willey PHOTODYNAMIC THERAPY PROCEDURE FOR SKIN DISEASES
CN107233303A (zh) * 2017-08-07 2017-10-10 苏州纳美特生物科技有限公司 一种氨基酮戊酸冷霜及其制备方法和应用
TWI719263B (zh) * 2017-10-27 2021-02-21 財團法人國家衛生研究院 用於鼻黏膜之奈米級乳液免疫載劑及其製備方法
US10959975B1 (en) 2017-11-02 2021-03-30 The Tetra Corporation Antifungal composition, method of making composition, and method of using composition
US10357567B1 (en) 2018-01-12 2019-07-23 Dusa Pharmaceuticals, Inc. Methods for photodynamic therapy
JP2021523230A (ja) * 2018-05-11 2021-09-02 フォーミュリティカ ピーティーワイ リミテッド サブミクロンエマルジョン
EP3583954A1 (en) * 2018-06-19 2019-12-25 neubourg skin care GmbH Nanodispersions of birch bark extract, electrospun fibers containing such nanodispersions and their use for the treatment of wounds
US11642411B2 (en) 2018-08-23 2023-05-09 Biofrontera Bioscience Gmbh Photodynamic therapy comprising two light exposures at different wavelengths
KR20210049159A (ko) * 2018-08-31 2021-05-04 케민 인더스트리즈, 인코포레이티드 수분산성 인지질 및 리소인지질을 위한 기술
CN113260257B (zh) * 2018-12-28 2022-09-06 南京善思生物科技有限公司 纳米农药制剂及其制备方法
CN110169990A (zh) * 2019-06-19 2019-08-27 苏普丘昆基蒂 牛至油治疗猪腹泻自乳化配方产品及制造工艺
CN114081851A (zh) * 2021-11-01 2022-02-25 苏州纳美特生物科技有限公司 保湿喷雾
WO2024208433A1 (en) * 2023-04-06 2024-10-10 Biofrontera Bioscience Gmbh Nanoemulsion without propylene glycol
CN120916750A (zh) * 2023-04-06 2025-11-07 生物前沿生物科学有限公司 不含丙二醇的纳米乳剂
WO2024208434A1 (en) * 2023-04-06 2024-10-10 Biofrontera Bioscience Gmbh Pressurized nanoemulsion
CN120981222A (zh) * 2023-04-06 2025-11-18 生物前沿生物科学有限公司 具有改善的他克莫司稳定性和皮肤渗透性的纳米乳制剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
US6559183B1 (en) * 1998-11-12 2003-05-06 Asat Ag Applied Science & Technology Nano-emulsion of 5-aminolevulinic acid

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR27650A (tr) * 1993-04-14 1995-06-14 Colgate Palmolive Co Bir glikol mono-alkil eteri iceren mikroemülsiyon temizleme bilesimi.
CA2158724A1 (en) * 1994-09-20 1996-03-21 Jue-Chen Liu Transdermally active pharmaceutical composition containing 5-aminolaevulinic acid
US5780010A (en) 1995-06-08 1998-07-14 Barnes-Jewish Hospital Method of MRI using avidin-biotin conjugated emulsions as a site specific binding system
SE9503143D0 (sv) * 1995-09-12 1995-09-12 Astra Ab New preparation
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
US5895786A (en) 1996-05-08 1999-04-20 New York Blood Center, Inc. Method for treating viral infections
EP0829206B1 (en) * 1996-09-16 2002-12-11 Societe Des Produits Nestle S.A. Edible micro-emulsion for coating food products and its use for browning and crisping in a microwave
DK0842606T3 (da) * 1996-11-13 2000-06-05 Procter & Gamble Desinficerende mikroemulsioner
TWI241915B (en) * 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
US6620437B2 (en) * 1998-07-30 2003-09-16 Colgate-Palmolive Co. Water-in-oil microemulsion for providing cosmetic attributes to fabric softening base composition
FR2787728B1 (fr) * 1998-12-23 2001-01-26 Oreal Nanoemulsion a base d'esters gras d'acide phosphorique, et ses utilisations dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique
FR2787703B1 (fr) * 1998-12-29 2001-01-26 Oreal Nanoemulsion a base d'ethers gras ethoxyles ou d'esters gras ethoxyles, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2788449B1 (fr) * 1999-01-14 2001-02-16 Oreal Nanoemulsion a base de citrates d'alkylether, et ses utilisations dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique
FR2795960B1 (fr) * 1999-07-05 2001-10-19 Sanofi Elf Microemulsions stables pour l'administration d'acides gras a l'homme ou a l'animal, et utilisation de ces microemulsions
US7919113B2 (en) * 1999-12-30 2011-04-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dispersible concentrate lipospheres for delivery of active agents
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
US20020155084A1 (en) * 2000-06-02 2002-10-24 The Regents Of The University Of The Michigan Nanoemulsion formulations
US6823387B1 (en) * 2000-06-23 2004-11-23 Microsoft Corporation System and method for enhancing a server's ability to withstand a “SYN flood” denial of service attack
EP2269645A3 (en) * 2000-08-16 2011-01-12 The General Hospital Corporation doing business as Massachusetts General Hospital Topical aminolevulinic acid-photodynamic therapy for acne vulgaris
JP2002302414A (ja) 2000-12-26 2002-10-18 Kokuriyuudou:Kk スフィンゴ脂質構造物質含有乳化組成物及びその製造方法
EP2545937A1 (en) * 2001-06-05 2013-01-16 The Regents Of The University Of Michigan Nanoemulsion vaccines
WO2003030926A1 (en) * 2001-10-05 2003-04-17 Procyte Corporation Stable solutions of peptide copper complexes and cosmetic and pharmaceutical formulations produced therefrom
JP2005527493A (ja) * 2002-01-23 2005-09-15 ライト サイエンシーズ コーポレイション 光線力学療法のためのシステムおよび方法
BR0314916A (pt) * 2002-10-25 2005-08-16 Foamix Ltd Espuma farmacêutica e cosmética
PT1469072E (pt) * 2003-04-17 2007-10-29 Affectis Pharmaceuticals Ag Meios e processos para o diagnóstico e tratamento de distúrbios afectivos
US20050208083A1 (en) * 2003-06-04 2005-09-22 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
WO2005027872A2 (en) * 2003-06-04 2005-03-31 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof
EP1598060A1 (en) 2004-05-18 2005-11-23 Nestec S.A. Oil-in-water emulsion for delivery
FR2872038A1 (fr) * 2004-06-23 2005-12-30 Rhodia Chimie Sa Composition cosmetique comprenant un polyorganosiloxane et ses utilisations
TWI365075B (en) * 2004-09-22 2012-06-01 Kao Corp Microemulsion
ATE412400T1 (de) * 2004-11-09 2008-11-15 Novagali Pharma Sa Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential
JP4444149B2 (ja) * 2005-03-30 2010-03-31 株式会社ナリス化粧品 超微細エマルジョンで構成される皮膚外用剤
BRPI0520076B1 (pt) * 2005-04-28 2018-05-08 Cosmo Oil Co Ltd preparação externa para pele, drogas preventivas/melhoradoras para aspereza de pele, para pele seca, e para rugas/manchas, métodos para prevenir/melhorar aspereza de pele, pele seca, e rugas/manchas, droga melhoradora de dermatite atópica, método para melhorar dermatite atópica, e, conjunto de preparações externas para pele
EP1938801A1 (en) * 2006-12-22 2008-07-02 Biofrontera Bioscience GmbH Nanoemulsion

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
US6559183B1 (en) * 1998-11-12 2003-05-06 Asat Ag Applied Science & Technology Nano-emulsion of 5-aminolevulinic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012502B2 (en) * 2010-09-14 2015-04-21 Sbi Pharmaceuticals Co., Ltd. Cancer heat therapy-enhancing agent

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