CN101573383B - 靶向肿瘤的针对卷曲同源物10的单克隆抗体及其用途 - Google Patents

靶向肿瘤的针对卷曲同源物10的单克隆抗体及其用途 Download PDF

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CN101573383B
CN101573383B CN200680055625.1A CN200680055625A CN101573383B CN 101573383 B CN101573383 B CN 101573383B CN 200680055625 A CN200680055625 A CN 200680055625A CN 101573383 B CN101573383 B CN 101573383B
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CN101573383A (zh
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中村祐辅
片桐丰雅
中鹤修一
远藤启吾
久原基树
八木香澄
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Oncotherapy Science Inc
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
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    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
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    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
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    • G01N33/57446Specifically defined cancers of stomach or intestine
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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CN200680055625.1A 2006-06-21 2006-08-24 靶向肿瘤的针对卷曲同源物10的单克隆抗体及其用途 Active CN101573383B (zh)

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US81525706P 2006-06-21 2006-06-21
US60/815,257 2006-06-21
PCT/JP2006/317155 WO2007148417A1 (en) 2006-06-21 2006-08-24 Tumor-targeting monoclonal antibodies to fzd10 and uses thereof

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EP (2) EP2386577A3 (cg-RX-API-DMAC7.html)
JP (1) JP5028635B2 (cg-RX-API-DMAC7.html)
KR (1) KR101351208B1 (cg-RX-API-DMAC7.html)
CN (1) CN101573383B (cg-RX-API-DMAC7.html)
BR (1) BRPI0621800B8 (cg-RX-API-DMAC7.html)
CA (1) CA2655289C (cg-RX-API-DMAC7.html)
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US20130230521A1 (en) 2013-09-05
EP2386577A9 (en) 2011-12-28
BRPI0621800B1 (pt) 2020-03-24
JP2009541204A (ja) 2009-11-26
RU2412203C2 (ru) 2011-02-20
BRPI0621800B8 (pt) 2022-01-04
ES2405618T3 (es) 2013-05-31
US8221751B2 (en) 2012-07-17
RU2009101788A (ru) 2010-08-10
CA2655289C (en) 2016-08-23
US20110044896A1 (en) 2011-02-24
BRPI0621800A2 (pt) 2011-12-20
US9139655B2 (en) 2015-09-22
EP2386577A3 (en) 2012-05-02
EP2386577A2 (en) 2011-11-16
JP5028635B2 (ja) 2012-09-19
KR101351208B1 (ko) 2014-01-14
CN101573383A (zh) 2009-11-04
WO2007148417A1 (en) 2007-12-27
CA2655289A1 (en) 2007-12-27
EP2044123B1 (en) 2013-03-13
EP2044123A1 (en) 2009-04-08
KR20090029275A (ko) 2009-03-20

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Inventor after: IIda Aritoshi

Inventor after: Katagiri Toyomasa

Inventor after: Nakatsuru Shuichi

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Inventor after: YAGI KASUMI

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