CN101569626B - 使用巴比土酸衍生物治疗运动障碍的方法 - Google Patents
使用巴比土酸衍生物治疗运动障碍的方法 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6756379B2 (en) * | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US6939873B2 (en) * | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| ATE413867T1 (de) | 2002-12-11 | 2008-11-15 | Taro Pharma Ind | Methode zur behandlung von bewegungsstörungen mit barbitursäure derivaten. |
| EP1781624A4 (en) * | 2004-07-02 | 2010-06-23 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID |
| EP1625848A1 (en) * | 2004-08-10 | 2006-02-15 | Taro Pharmaceuticals North America, Inc. | Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid |
| WO2008066704A2 (en) * | 2006-11-14 | 2008-06-05 | Taro Pharmaceuticals North America, Inc. | Method of improving bioavailability for non-sedating barbiturates |
| US9056817B2 (en) * | 2011-09-12 | 2015-06-16 | Council Of Scientific And Industrial Research | Arylated β-dicarbonyl compounds and process for the preparation thereof |
| IT201700059814A1 (it) * | 2017-05-31 | 2018-12-01 | Antonio Costantini | Vitamina b1 in alte dosi per uso nel trattamento medico di alcune malattie neurodegenerative sporadiche , di origine genetica e delle cefalee primarie |
| JP7357432B2 (ja) | 2017-10-10 | 2023-10-06 | 信越化学工業株式会社 | Ｅｕｖ用ペリクルフレーム、ペリクル、ペリクル付露光原版、露光方法、及び半導体の製造方法 |
| WO2023077030A1 (en) * | 2021-10-29 | 2023-05-04 | Gilead Sciences, Inc. | Cd73 compounds |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002007729A1 (en) * | 2000-07-26 | 2002-01-31 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| CN100502871C (zh) * | 2002-12-11 | 2009-06-24 | 塔罗制药工业有限公司 | 巴比土酸衍生物在制备用于治疗运动障碍的药物中的应用 |
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| DE946804C (de) | 1952-02-28 | 1956-08-09 | Emanuel Merck Ohg | Verfahren zur Herstellung von schwefelhaltigen Abkoemmlingen der Barbitursaeure |
| DE1103339B (de) | 1959-02-04 | 1961-03-30 | Chemische Werke Radebeul Veb | Verfahren zur Herstellung von in 5-Stellung crotylierten, basisch substituierten Barbitursaeure-derivaten |
| DE1100639B (de) | 1959-03-24 | 1961-03-02 | Chemische Werke Radebeul Veb | Verfahren zur Herstellung von basisch substituierten Barbitursaeure-derivaten |
| GB966098A (en) | 1959-11-23 | 1964-08-06 | Sapos Sa | Barbiturate derivatives |
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| US3919427A (en) | 1972-06-02 | 1975-11-11 | Kendall & Co | Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds |
| US3900475A (en) | 1972-06-26 | 1975-08-19 | Kendall & Co | Certain phenobarbital salts |
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| US4029662A (en) | 1976-04-30 | 1977-06-14 | Bristol-Myers Company | Method of making barbituric acid derivatives |
| DE2622981A1 (de) | 1976-05-21 | 1977-12-08 | Unisearch Ltd | Verfahren zur herstellung von halogenalkylierten verbindungen |
| US4260769A (en) | 1977-04-22 | 1981-04-07 | Interx Research Corporation | 5,5-Diphenylhydantoins |
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| US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6939873B2 (en) | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| WO2003063872A1 (en) | 2002-01-30 | 2003-08-07 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbituric acid derivatives |
| EP1781624A4 (en) | 2004-07-02 | 2010-06-23 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID |
| EP1625848A1 (en) | 2004-08-10 | 2006-02-15 | Taro Pharmaceuticals North America, Inc. | Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid |
| WO2008066704A2 (en) | 2006-11-14 | 2008-06-05 | Taro Pharmaceuticals North America, Inc. | Method of improving bioavailability for non-sedating barbiturates |
-
2003
- 2003-12-11 AT AT03812970T patent/ATE413867T1/de not_active IP Right Cessation
- 2003-12-11 AU AU2003302897A patent/AU2003302897C1/en not_active Ceased
- 2003-12-11 DE DE60324703T patent/DE60324703D1/de not_active Expired - Lifetime
- 2003-12-11 EP EP03812970A patent/EP1569627B1/en not_active Expired - Lifetime
- 2003-12-11 JP JP2004558727A patent/JP4739760B2/ja not_active Expired - Fee Related
- 2003-12-11 EP EP08168690A patent/EP2156839A1/en not_active Withdrawn
- 2003-12-11 TW TW096136184A patent/TW200822927A/zh unknown
- 2003-12-11 ES ES03812970T patent/ES2315569T3/es not_active Expired - Lifetime
- 2003-12-11 MX MXPA05006271A patent/MXPA05006271A/es active IP Right Grant
- 2003-12-11 CA CA2505335A patent/CA2505335C/en not_active Expired - Fee Related
- 2003-12-11 US US10/735,514 patent/US7166610B2/en not_active Expired - Fee Related
- 2003-12-11 CN CN2009101372903A patent/CN101569626B/zh not_active Expired - Fee Related
- 2003-12-11 AR ARP030104584A patent/AR042444A1/es unknown
- 2003-12-11 TW TW092135084A patent/TWI334780B/zh not_active IP Right Cessation
- 2003-12-11 WO PCT/US2003/039530 patent/WO2004052350A2/en not_active Ceased
- 2003-12-11 CN CNB200380104405XA patent/CN100502871C/zh not_active Expired - Fee Related
- 2003-12-11 PT PT03812970T patent/PT1569627E/pt unknown
- 2003-12-11 BR BR0317289-9A patent/BR0317289A/pt not_active IP Right Cessation
- 2003-12-11 CL CL200302588A patent/CL2003002588A1/es unknown
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2005
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2006
- 2006-02-16 US US11/355,339 patent/US7776871B2/en not_active Expired - Fee Related
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2009
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- 2010-03-02 AU AU2010200787A patent/AU2010200787A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002007729A1 (en) * | 2000-07-26 | 2002-01-31 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| CN100502871C (zh) * | 2002-12-11 | 2009-06-24 | 塔罗制药工业有限公司 | 巴比土酸衍生物在制备用于治疗运动障碍的药物中的应用 |
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