CN101563361B - 能够感染犬科动物的流感病毒及其用途 - Google Patents

能够感染犬科动物的流感病毒及其用途 Download PDF

Info

Publication number
CN101563361B
CN101563361B CN200680041958.9A CN200680041958A CN101563361B CN 101563361 B CN101563361 B CN 101563361B CN 200680041958 A CN200680041958 A CN 200680041958A CN 101563361 B CN101563361 B CN 101563361B
Authority
CN
China
Prior art keywords
virus
influenza
dogs
canine
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200680041958.9A
Other languages
English (en)
Chinese (zh)
Other versions
CN101563361A (zh
Inventor
P·C·克劳福德
P·J·吉布斯
E·J·杜博维
R·O·多尼斯
J·卡茨
A·I·克利莫夫
N·P·拉克什曼
M·A·卢姆
D·G·E·古瓦尔特斯
M·W·梅伦坎普
N·J·考克斯
W·L·卡斯尔曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Centers of Disease Control and Prevention CDC
Schering Plough Corp
University of Florida Research Foundation Inc
Merck and Co Inc
Original Assignee
US Government Represented By Secretary Of Department Of Health And Public Health Centers For Disease Control
Intervet International BV
Cornell Research Foundation Inc
Centers of Disease Control and Prevention CDC
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Government Represented By Secretary Of Department Of Health And Public Health Centers For Disease Control, Intervet International BV, Cornell Research Foundation Inc, Centers of Disease Control and Prevention CDC, University of Florida Research Foundation Inc filed Critical US Government Represented By Secretary Of Department Of Health And Public Health Centers For Disease Control
Priority to CN201310741621.0A priority Critical patent/CN104017775B/zh
Priority to CN202310548441.4A priority patent/CN117587038A/zh
Publication of CN101563361A publication Critical patent/CN101563361A/zh
Application granted granted Critical
Publication of CN101563361B publication Critical patent/CN101563361B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/11Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16141Use of virus, viral particle or viral elements as a vector
    • C12N2760/16143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/11Orthomyxoviridae, e.g. influenza virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
CN200680041958.9A 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途 Active CN101563361B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201310741621.0A CN104017775B (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途
CN202310548441.4A CN117587038A (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US72844905P 2005-10-19 2005-10-19
US60/728,449 2005-10-19
US75488105P 2005-12-29 2005-12-29
US60/754,881 2005-12-29
US75916206P 2006-01-14 2006-01-14
US60/759,162 2006-01-14
US76145106P 2006-01-23 2006-01-23
US60/761,451 2006-01-23
US77908006P 2006-03-03 2006-03-03
US60/779,080 2006-03-03
US40941606A 2006-04-21 2006-04-21
US11/409,416 2006-04-21
PCT/US2006/041061 WO2007047938A2 (en) 2005-10-19 2006-10-19 Influenza viruses able to infect canids, uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN202310548441.4A Division CN117587038A (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途
CN201310741621.0A Division CN104017775B (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途

Publications (2)

Publication Number Publication Date
CN101563361A CN101563361A (zh) 2009-10-21
CN101563361B true CN101563361B (zh) 2014-01-29

Family

ID=37885846

Family Applications (3)

Application Number Title Priority Date Filing Date
CN200680041958.9A Active CN101563361B (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途
CN201310741621.0A Active CN104017775B (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途
CN202310548441.4A Pending CN117587038A (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201310741621.0A Active CN104017775B (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途
CN202310548441.4A Pending CN117587038A (zh) 2005-10-19 2006-10-19 能够感染犬科动物的流感病毒及其用途

Country Status (14)

Country Link
EP (2) EP1945659B9 (enExample)
JP (3) JP2009512449A (enExample)
KR (2) KR101548436B1 (enExample)
CN (3) CN101563361B (enExample)
AU (1) AU2006304747B2 (enExample)
BR (1) BRPI0617735B1 (enExample)
CA (2) CA3090231A1 (enExample)
ES (2) ES2496315T3 (enExample)
IL (2) IL190906A (enExample)
MX (3) MX395177B (enExample)
NO (2) NO346351B1 (enExample)
NZ (4) NZ567809A (enExample)
RU (2) RU2520081C2 (enExample)
WO (1) WO2007047938A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2570758T3 (es) * 2005-04-21 2016-05-20 Univ Florida Materiales y métodos para el control de enfermedades respiratorias en cánidos
US20080241184A1 (en) * 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
JP5257364B2 (ja) 2006-10-25 2013-08-07 インターベツト・インターナシヨナル・ベー・ベー ネコインフルエンザワクチン及び使用方法
AU2011224507A1 (en) * 2010-03-10 2012-08-30 Intervet International B.V. Method for protecting against disease caused by secondary pathogens
CN101838708B (zh) * 2010-03-30 2012-07-18 华南农业大学 一种检测犬流感的方法
CN102220293B (zh) * 2011-05-26 2012-12-19 中国农业科学院上海兽医研究所 犬流感重组病毒及其制备方法和应用
CN103242433B (zh) * 2012-02-14 2016-12-14 中国医学科学院病原生物学研究所 一种腺病毒非结构蛋白免疫原、其抗体及应用
CN104436157A (zh) 2013-09-23 2015-03-25 恩金生物有限公司 流感疫苗和治疗
US10080792B2 (en) 2013-09-23 2018-09-25 Engen Bio, Inc. Influenza vaccine and therapy
US10555998B2 (en) 2014-11-24 2020-02-11 Intervet Inc. Inactivated equine influenza virus vaccines
JP2015120709A (ja) * 2015-01-09 2015-07-02 ラボラトリオ アヴィメキシコ エスエー ディーイー シーヴィーLaboratorio Avi−Mex,S.A. De C.V. 遺伝子組み換え不活性化ウィルスベクターワクチン
CN104911150B (zh) * 2015-05-27 2018-05-01 华南农业大学 一种h3n2犬流感病毒的单克隆抗体杂交瘤细胞株的建立及其单克隆抗体的制备与应用
CN106636475B (zh) * 2017-03-01 2020-05-22 中国农业大学 一种检测北美h3n8亚型犬流感病毒的引物组及其应用
CN113905759A (zh) * 2019-02-27 2022-01-07 罗切斯特大学 用于预防和控制马的马流感病毒(eiv)的多价减毒活流感疫苗
WO2021236488A1 (en) * 2020-05-18 2021-11-25 Thomas Jefferson University Viral sample collection
JP2023546076A (ja) * 2020-10-08 2023-11-01 コントロールポイント インコーポレイテッド 呼吸器感染症を検出するための方法及び器具
CN112410467A (zh) * 2020-11-23 2021-02-26 深圳市赛格诺生物科技有限公司 一种检测甲型和乙型流感病毒的冻干型荧光rt-pcr试剂及方法
WO2024196133A1 (ko) * 2023-03-21 2024-09-26 고려대학교 산학협력단 교차 면역원성을 갖는 h3 아형 인플루엔자 바이러스 및 이를 포함하는 백신
KR102746574B1 (ko) 2023-11-27 2024-12-24 김태윤 반려동물의 호흡기 건강 개선용 조성물
KR20250108327A (ko) 2024-01-08 2025-07-15 건국대학교 산학협력단 반려동물 치료를 위한 코삽입관 고정장치
US12233100B1 (en) 2024-10-31 2025-02-25 Tae Yoon Kim Composition for improving respiratory health of companion animals

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101253267A (zh) * 2005-04-21 2008-08-27 佛罗里达大学研究基金公司 用于犬科动物中呼吸系统疾病控制的物质和方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034322A (en) 1983-01-17 1991-07-23 Monsanto Company Chimeric genes suitable for expression in plant cells
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5106739A (en) 1989-04-18 1992-04-21 Calgene, Inc. CaMv 355 enhanced mannopine synthase promoter and method for using same
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5612487A (en) 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
US5484719A (en) 1991-08-26 1996-01-16 Edible Vaccines, Inc. Vaccines produced and administered through edible plants
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
RU2193065C2 (ru) * 1994-03-14 2002-11-20 Мерк энд Ко. Инк. Конструкция днк (варианты), днк-вектор, иммуногенная композиция против вируса гриппа, способ индукции иммунного ответа, вакцина и способ вакцинации
GB9524395D0 (en) 1995-11-29 1996-01-31 Nickerson Biocem Ltd Promoters
US6252139B1 (en) 1996-07-18 2001-06-26 The Salk Institute For Biological Studies Method of increasing growth and yield in plants
US6063385A (en) 1997-11-07 2000-05-16 Wisconsin Alumni Research Foundation DNA vaccine for parvovirus
US6472375B1 (en) 1998-04-16 2002-10-29 John Wayne Cancer Institute DNA vaccine and methods for its use
GB9809666D0 (en) * 1998-05-06 1998-07-01 Isis Innovation Modified viruses
US6177082B1 (en) * 1998-08-13 2001-01-23 The University Of Pittsburgh-Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
EP1133556B1 (en) 1998-11-24 2006-02-08 Pioneer Hi-Bred International, Inc. Root-preferred promoters and their use
EP1035209A1 (en) * 1999-03-06 2000-09-13 ARTEMIS Pharmaceuticals GmbH Stable recombinant influenza viruses free of helper viruses
GB9916794D0 (en) * 1999-07-16 1999-09-22 Isis Innovation In vitro virus reconstitution
AU6454700A (en) * 1999-07-30 2001-02-19 Isis Innovation Limited Attenuated influenza virus useful as vaccine
US6398774B1 (en) 1999-09-29 2002-06-04 Heska Corporation Intranasal delivery system
DE19960843A1 (de) 1999-12-16 2001-06-28 Florian Grundler Wurzelspezifischer Promotor
US6455760B1 (en) 2000-11-16 2002-09-24 The Salk Institute Of Biological Studies Expression of flavin-containing monoxygenases in plants
US20040067506A1 (en) 2000-12-04 2004-04-08 Ben Scheres Novel root specific promoter driving the expression of a novel lrr receptor-like kinase
PL212212B1 (pl) * 2001-07-27 2012-08-31 Wyeth Corp Kompozycja szczepionki przeciwko zakażeniu wirusem Zachodniego Nilu, kompozycja końskiej szczepionki, szczepionka wirusa Zachodniego Nilu oraz zastosowania
HUE050222T2 (hu) * 2002-02-13 2020-11-30 Wisconsin Alumni Res Found Szignál influenzavírus-vektorok pakolására
US20050158342A1 (en) * 2003-12-23 2005-07-21 Medimmune, Inc. Multi plasmid system for the production of influenza virus
US7285656B2 (en) 2002-04-26 2007-10-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Natural Resources Canada, Canadian Forest Service Root-specific conifer gene promoter and its use
AU2003294533A1 (en) * 2002-12-19 2004-07-14 Universite Laval Molecular methods and compositions for detecting and quantifying respiratory viruses
US20040123349A1 (en) 2002-12-20 2004-06-24 Qi Xie SINAT5, an Arabidopsis thaliana gene promotes ubiquitin related degradation
JP2004285019A (ja) * 2003-03-25 2004-10-14 Kyoto Prefecture 生体外異物の不活化方法
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
WO2006073436A2 (en) * 2004-04-29 2006-07-13 The Trustees Of Columbia University In The City Of New York Mass tag pcr for multiplex diagnostics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101253267A (zh) * 2005-04-21 2008-08-27 佛罗里达大学研究基金公司 用于犬科动物中呼吸系统疾病控制的物质和方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CRAWFORD PC ET AL.Influenza A virus (A/canine/Texas/1/2004(H3N8)) hemagglutinin gene,DQ124196,1695bp,RNA linear,partial cds.《NCBI》.2005,1-2. *
CRAWFORD PC ET AL.Transmission of Equine influenza virus to dogs.《SCIENCE》.2005,第310卷(第5747期),482-485. *
Manuguerra J et al.Natural infection of dogs by influenza C virus.《Research in Virology》.1992,第143卷(第1期),199-204. *
PEEK SF ET AL.Acute respiratory distress syndrome and fatal interstitial pneumonia associated with equine influenza in a neonatal foal.《JOURNAL OF VETERINARY INTERNAL MEDICINE》.2004,第18卷(第1期),132-134. *

Also Published As

Publication number Publication date
HK1167660A1 (en) 2013-01-11
ES2393406T3 (es) 2012-12-21
MX395177B (es) 2025-03-25
JP6220361B2 (ja) 2017-10-25
RU2020100036A (ru) 2021-07-09
IL190906A0 (en) 2008-11-03
BRPI0617735A2 (pt) 2011-08-02
MX341842B (es) 2016-09-02
RU2711807C2 (ru) 2020-01-22
CA2626489A1 (en) 2007-04-26
RU2520081C2 (ru) 2014-06-20
KR101597534B1 (ko) 2016-02-26
IL226253A0 (en) 2013-06-27
EP2407480A1 (en) 2012-01-18
EP2407480B1 (en) 2014-07-16
CN104017775B (zh) 2023-05-30
WO2007047938A2 (en) 2007-04-26
RU2008119461A (ru) 2009-12-27
JP2009512449A (ja) 2009-03-26
NZ717751A (en) 2019-09-27
CN117587038A (zh) 2024-02-23
KR20130048800A (ko) 2013-05-10
NO20082257L (no) 2008-07-18
NO346351B1 (no) 2022-06-20
RU2014101481A (ru) 2015-07-27
ES2496315T3 (es) 2014-09-18
MX2008005234A (es) 2008-09-23
IL190906A (en) 2017-03-30
CN104017775A (zh) 2014-09-03
EP1945659A2 (en) 2008-07-23
AU2006304747A1 (en) 2007-04-26
JP2015186478A (ja) 2015-10-29
EP1945659B1 (en) 2012-08-15
NZ567809A (en) 2012-06-29
EP1945659B9 (en) 2013-05-29
JP5974397B2 (ja) 2016-08-23
BRPI0617735B1 (pt) 2022-05-17
KR20080093018A (ko) 2008-10-17
NZ735684A (en) 2020-04-24
KR101548436B1 (ko) 2015-08-28
CA2626489C (en) 2020-10-27
NO2022022I1 (no) 2022-06-09
CN101563361A (zh) 2009-10-21
IL226253A (en) 2017-08-31
AU2006304747B2 (en) 2013-10-03
JP2012254080A (ja) 2012-12-27
NZ627888A (en) 2016-03-31
CA3090231A1 (en) 2007-04-26
HK1118563A1 (en) 2009-02-13
WO2007047938A3 (en) 2008-03-20

Similar Documents

Publication Publication Date Title
US11160859B2 (en) Materials and methods for respiratory disease control in canines
RU2711807C2 (ru) Вирус гриппа, способный инфицировать собачьих, и его применение
CN103451158B (zh) 用于犬科动物中呼吸系统疾病控制的物质和方法
AU2020264347B2 (en) Influenza viruses able to infect canids, uses thereof
US11865172B2 (en) Materials and methods for respiratory disease control in canines
RU2802222C2 (ru) Вирус гриппа, способный инфицировать собачьих, и его применение
AU2012238228B2 (en) Materials and methods for respiratory disease control in canines
HK1167660B (en) Materials for respiratory disease control in canines
HK1118563B (en) Influenza viruses able to infect canids, uses thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEP

Free format text: FORMER OWNER: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEPARTMENT OF HEALTH CORNELL RESEARCH FOUNDATION AMERICA SCHERING-PLOUGH CORP.

Effective date: 20140619

Owner name: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEP

Free format text: FORMER OWNER: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEPARTMENT OF HEALTH CORNELL RESEARCH FOUNDATION MERK + CO. INC.

Effective date: 20140619

Owner name: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEP

Free format text: FORMER OWNER: CENTERS FOR DISEASE CONTROL AND PREVENTION, US DEPARTMENT OF HEALTH CORNELL RESEARCH FOUNDATION INTERVET INTERNATIONAL B. V.

Effective date: 20140619

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20140619

Address after: American Florida

Patentee after: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee after: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee after: CORNELL RESEARCH FOUNDATION, Inc.

Address before: American Florida

Patentee before: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee before: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee before: CORNELL RESEARCH FOUNDATION, Inc.

Patentee before: MERCK & Co.,Inc.

Effective date of registration: 20140619

Address after: American Florida

Patentee after: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee after: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee after: CORNELL RESEARCH FOUNDATION, Inc.

Patentee after: MERCK & Co.,Inc.

Address before: American Florida

Patentee before: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee before: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee before: CORNELL RESEARCH FOUNDATION, Inc.

Patentee before: The United States Schering plough

Effective date of registration: 20140619

Address after: American Florida

Patentee after: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee after: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee after: CORNELL RESEARCH FOUNDATION, Inc.

Patentee after: The United States Schering plough

Address before: American Florida

Patentee before: University OF FLORIDA RESEARCH FOUNDATION, INC.

Patentee before: CENTERS FOR DISEASE CONTROL & PREVENTION

Patentee before: CORNELL RESEARCH FOUNDATION, Inc.

Patentee before: Intervet International Co.,Ltd.