AU4930001A - Cold-adapted equine influenza viruses - Google Patents
Cold-adapted equine influenza virusesInfo
- Publication number
- AU4930001A AU4930001A AU4930001A AU4930001A AU4930001A AU 4930001 A AU4930001 A AU 4930001A AU 4930001 A AU4930001 A AU 4930001A AU 4930001 A AU4930001 A AU 4930001A AU 4930001 A AU4930001 A AU 4930001A
- Authority
- AU
- Australia
- Prior art keywords
- viruses
- cold
- equine influenza
- influenza virus
- influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
- C12N2760/16164—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment confers at least one identifying phenotype of the cold-adapted equine influenza virus, such as cold-adaptation, temperature sensitivity, dominant interference, or attenuation. Such viruses are formulated into therapeutic compositions to protect animals from diseases caused by influenza A viruses, and in particular, to protect horses from disease caused by equine influenza virus. The present invention also includes methods to protect animals from diseases caused by influenza A virus or other infectious agents utilizing the claimed therapeutic compositions. Such methods include using a therapeutic composition as a vaccine to generate a protective immune response in an animal prior to exposure to an infectious agent, as well as using a therapeutic composition as a treatment for an animal that has been recently infected with an infectious agent leading to respiratory disease, or is likely to be subsequently exposed to such an agent in a few days whereby the therapeutic composition reduces such respiratory disease, even in the absence of antibody-mediated immunity. The present invention also provides methods to produce cold-adapted equine influenza viruses, and reassortant influenza A viruses having at least one genome segment of an equine influenza virus generated by cold-adaptation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19432500P | 2000-04-03 | 2000-04-03 | |
PCT/US2001/008968 WO2001074386A2 (en) | 2000-04-03 | 2001-03-21 | Cold-adapted equine influenza viruses |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4930001A true AU4930001A (en) | 2001-10-15 |
Family
ID=22717146
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU4930001A Pending AU4930001A (en) | 2000-04-03 | 2001-03-21 | Cold-adapted equine influenza viruses |
AU2001249300A Expired AU2001249300B2 (en) | 2000-04-03 | 2001-03-21 | Cold-adapted equine influenza viruses |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001249300A Expired AU2001249300B2 (en) | 2000-04-03 | 2001-03-21 | Cold-adapted equine influenza viruses |
Country Status (8)
Country | Link |
---|---|
US (2) | US7029903B2 (en) |
EP (1) | EP1267920B1 (en) |
JP (1) | JP2003528925A (en) |
AT (1) | ATE350056T1 (en) |
AU (2) | AU4930001A (en) |
CA (1) | CA2403979A1 (en) |
DE (1) | DE60125736D1 (en) |
WO (1) | WO2001074386A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004003572A1 (en) | 2004-01-23 | 2005-08-18 | Bavarian Nordic A/S | Monoparamunity inducers based on attenuated rabbit myxomaviruses |
US7572620B2 (en) | 2005-01-11 | 2009-08-11 | Wisconsin Alumni Research Foundation | H3 equine influenza A virus |
US11865172B2 (en) | 2005-04-21 | 2024-01-09 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
US7959929B2 (en) | 2005-04-21 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
US8647637B2 (en) | 2009-01-30 | 2014-02-11 | The Board Of Regents For Oklahoma State University | Immunogenic compositions, vaccines and diagnostics based on canine distemper viruses circulating in north american dogs |
WO2010111687A2 (en) | 2009-03-27 | 2010-09-30 | Academia Sinica | Methods and compositions for immunization against virus |
CA2791396C (en) * | 2010-03-10 | 2019-08-27 | Intervet International B.V. | Method for protecting against disease caused by secondary pathogens |
TWI537385B (en) * | 2010-11-04 | 2016-06-11 | 中央研究院 | Methods for producing virus particles with simplified glycosylation of surface proteins |
JP6313752B2 (en) * | 2012-05-31 | 2018-04-18 | ゾエティス・エルエルシー | B. Vaccination with canine respiratory coronavirus to protect against B. bronchiseptica infection |
JP6560056B2 (en) * | 2015-08-07 | 2019-08-14 | ウィスコンシン アルムニ リサーチ ファンデイション | H3 equine influenza A virus |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3518347A (en) | 1965-05-28 | 1970-06-30 | Inst Microbiologie Et D Hygien | Vaccine for equine influenza |
US3992522A (en) | 1973-01-24 | 1976-11-16 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Temperature-sensitive recombinant mutant viruses and a process for producing same |
CA1204069A (en) | 1982-04-16 | 1986-05-06 | Cornell Research Foundation, Inc. | Temperature sensitive reassortant viruses and a vaccine against equine influenza |
US4683137A (en) | 1982-04-16 | 1987-07-28 | Cornell Research Foundation, Inc. | Temperature sensitive reassortant viruses and a vaccine against equine influenza |
GB8300467D0 (en) | 1983-01-08 | 1983-02-09 | Wellcome Found | Equine influenza |
US4631191A (en) | 1985-06-20 | 1986-12-23 | Biotechnology Research Partners, Ltd. | Methods and compositions useful in preventing equine influenza |
US4920213A (en) | 1985-06-20 | 1990-04-24 | Biotechnology Research Partners, Ltd. | Method and compositions useful in preventing equine influenza |
US5149531A (en) | 1990-06-27 | 1992-09-22 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of using cold-adapted live influenza virus vaccine as an antiviral agent against influenza |
IL105456A (en) | 1992-04-21 | 1996-12-05 | American Home Prod | Attenuated respiratory syncytial virus vaccine compositions |
US5690937A (en) | 1995-06-05 | 1997-11-25 | Aviron | Temperature sensitive clustered changed-to-alanine mutants of influenza virus PB2 gene |
US6177082B1 (en) | 1998-08-13 | 2001-01-23 | The University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Cold-adapted equine influenza viruses |
-
2001
- 2001-03-21 JP JP2001572128A patent/JP2003528925A/en active Pending
- 2001-03-21 AU AU4930001A patent/AU4930001A/en active Pending
- 2001-03-21 WO PCT/US2001/008968 patent/WO2001074386A2/en active IP Right Grant
- 2001-03-21 US US10/239,972 patent/US7029903B2/en not_active Expired - Lifetime
- 2001-03-21 DE DE60125736T patent/DE60125736D1/en not_active Expired - Lifetime
- 2001-03-21 AU AU2001249300A patent/AU2001249300B2/en not_active Expired
- 2001-03-21 CA CA002403979A patent/CA2403979A1/en not_active Abandoned
- 2001-03-21 EP EP01922507A patent/EP1267920B1/en not_active Expired - Lifetime
- 2001-03-21 AT AT01922507T patent/ATE350056T1/en not_active IP Right Cessation
-
2006
- 2006-01-17 US US11/332,989 patent/US20060121521A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040223980A1 (en) | 2004-11-11 |
US20060121521A1 (en) | 2006-06-08 |
EP1267920A2 (en) | 2003-01-02 |
EP1267920B1 (en) | 2007-01-03 |
DE60125736D1 (en) | 2007-02-15 |
ATE350056T1 (en) | 2007-01-15 |
AU2001249300B2 (en) | 2006-02-16 |
WO2001074386A3 (en) | 2002-05-23 |
CA2403979A1 (en) | 2001-10-11 |
US7029903B2 (en) | 2006-04-18 |
WO2001074386A2 (en) | 2001-10-11 |
JP2003528925A (en) | 2003-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE358722T1 (en) | COLD-ADAPTABLE HORSES INFLUENZA VIRUSES | |
WO2001060849A3 (en) | Cold-adapted equine influenza viruses | |
TW200730188A (en) | Vaccines and methods to treat canine influenza | |
NO20061912L (en) | Vaccine compositions comprising an interleukin 18 and saponin adjuvant system | |
UA41315C2 (en) | VACCINE COMPOSITION AGAINST RESPIRATORY-SYNCITIAL VIRUS, METHOD OF STIMULATION OF INDIVIDUAL'S IMMUNE SYSTEM FOR INDUSTRIAL INDUCTION | |
CO5611162A2 (en) | METHODS TO PREVENT REPRODUCTIVE DISEASES IN VACCINE LIVESTOCK | |
AU4930001A (en) | Cold-adapted equine influenza viruses | |
EP2078083A4 (en) | A novel canine influenza virus and vaccine therefore | |
MXPA02004627A (en) | Vaccines for mycoplasma bovis. | |
JP2007197470A5 (en) | ||
MX2022010373A (en) | Vaccine against african swine fever virus infection. | |
AU9215101A (en) | Vaccines containing ribavirin and methods of use thereof | |
WO2007036735A3 (en) | Immunogenic agents againts burkholderia psudomallei and/or burkholderia mallei, comprising lipopolysaccharide, capsular polysaccharide and/or proteins from burkholderia psuedomallei | |
WO2004043404A3 (en) | Process for designing inhibitors of influenza virus non-structural protein 1 | |
MXPA03009763A (en) | Foot and mouth disease virus vaccine. | |
JP2003528925A5 (en) | ||
WO2007135420A3 (en) | Defective interfering virus | |
HUP9700975A2 (en) | Live attenuated rtx-producing bacteria of the family pasteurellaceae | |
YU65102A (en) | In ovo protection against infectious bronchitis | |
DK1132466T3 (en) | Chicken anemia virus with low pathogenicity | |
Thomson et al. | Foot and Mouth Disease in Southern Africa: Re-evaluation of the approach to control | |
HUP0202738A2 (en) | Equine herpes virus temperature sensitive mutant and live vaccine thereof | |
NO20014372D0 (en) | Isolation and partial characterization of a novel antiprocferative component from human leukocytes | |
Kirkbride et al. | Rabies risk from contact with bats | |
HUP0402548A2 (en) | An avian embryo particulate biomass for the production of virus antigens |