CN101519442B - Method for inducing silkworms to produce antibacterial peptides - Google Patents
Method for inducing silkworms to produce antibacterial peptides Download PDFInfo
- Publication number
- CN101519442B CN101519442B CN2009101164633A CN200910116463A CN101519442B CN 101519442 B CN101519442 B CN 101519442B CN 2009101164633 A CN2009101164633 A CN 2009101164633A CN 200910116463 A CN200910116463 A CN 200910116463A CN 101519442 B CN101519442 B CN 101519442B
- Authority
- CN
- China
- Prior art keywords
- silkworms
- antibacterial peptides
- silkworm
- hungry
- inducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000255789 Bombyx mori Species 0.000 title claims abstract description 38
- 238000000034 method Methods 0.000 title claims abstract description 28
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 16
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 15
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 15
- 230000001939 inductive effect Effects 0.000 title claims abstract description 14
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 6
- 240000000249 Morus alba Species 0.000 claims abstract description 6
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims description 23
- 102000044503 Antimicrobial Peptides Human genes 0.000 claims description 10
- 108700042778 Antimicrobial Peptides Proteins 0.000 claims description 10
- 238000007710 freezing Methods 0.000 claims description 9
- 230000008014 freezing Effects 0.000 claims description 9
- 238000004321 preservation Methods 0.000 claims description 8
- 235000003642 hunger Nutrition 0.000 claims description 3
- 241000700605 Viruses Species 0.000 abstract description 7
- 241000894006 Bacteria Species 0.000 abstract description 6
- 238000000605 extraction Methods 0.000 abstract description 4
- 238000002347 injection Methods 0.000 abstract description 3
- 239000007924 injection Substances 0.000 abstract description 3
- 239000006228 supernatant Substances 0.000 description 5
- 230000006698 induction Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000361919 Metaphire sieboldi Species 0.000 description 1
- 241000257159 Musca domestica Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000001857 anti-mycotic effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000002543 antimycotic Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005847 immunogenicity Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 238000005360 mashing Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000255 pathogenic effect Toxicity 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Induction method | Injection | Starvation method | Normal silkworm |
Antibacterial circle diameter (mm) | 2.1 | 2.3 | 1.4 |
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101164633A CN101519442B (en) | 2009-03-31 | 2009-03-31 | Method for inducing silkworms to produce antibacterial peptides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101164633A CN101519442B (en) | 2009-03-31 | 2009-03-31 | Method for inducing silkworms to produce antibacterial peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101519442A CN101519442A (en) | 2009-09-02 |
CN101519442B true CN101519442B (en) | 2011-09-28 |
Family
ID=41080264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009101164633A Expired - Fee Related CN101519442B (en) | 2009-03-31 | 2009-03-31 | Method for inducing silkworms to produce antibacterial peptides |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101519442B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102613249A (en) * | 2012-02-22 | 2012-08-01 | 湛江师范学院 | Process for preparing board-spectrum antibiotics by immune induction biotechnology |
CN103667303A (en) * | 2013-12-04 | 2014-03-26 | 浙江省海洋开发研究院 | Expression method of antibacterial peptide Hclocidin18 in escherichia coli |
CN103621564B (en) * | 2013-12-17 | 2016-05-25 | 湛江师范学院 | A kind of preparation method of biological antibiosis agent |
CN103641631B (en) * | 2013-12-17 | 2015-05-13 | 湛江师范学院 | Broad-spectrum antibacterial biological fertilizer |
CN104388508A (en) * | 2014-10-24 | 2015-03-04 | 江西省新龙生物科技有限公司 | Method for splitting insect body by utilizing insect virus to extract insect peptide |
CN110150478A (en) * | 2019-06-28 | 2019-08-23 | 青岛宝创生物科技有限公司 | A kind of feed addictive and the preparation method and application thereof reducing mastitis for milk cows disease incidence |
CN118047841B (en) * | 2024-04-09 | 2024-06-11 | 中国农业科学院农业基因组研究所 | Fermented mulberry leaf antibacterial peptide Squ and application thereof |
-
2009
- 2009-03-31 CN CN2009101164633A patent/CN101519442B/en not_active Expired - Fee Related
Non-Patent Citations (3)
Title |
---|
孙海新等.家蚕抗菌肽研究进展.《北方蚕业》.2003, * |
董占鹏.蚕类抗菌肽及其研究进展.《蚕学通讯》.2003, * |
黄自然等.注射大肠杆菌诱导柞蚕蛹血淋巴产生抗菌物质.《华南农学院学报》.1981, * |
Also Published As
Publication number | Publication date |
---|---|
CN101519442A (en) | 2009-09-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101519442B (en) | Method for inducing silkworms to produce antibacterial peptides | |
JP4771379B2 (en) | Fermentation and culture method, plant fermented extract, plant fermented extract powder and blended plant fermented extract | |
CN103844143B (en) | Tilapia mossambica prevention streptococcosis compound Chinese herbal medicinal feed additive | |
CN102228238B (en) | Integrated utilization technology of mulberry leaves | |
CN102599339A (en) | Method for removing saponin from Camellia oleifera seed meal by using compound bacteria | |
CN105231071A (en) | Method for preparing formula feed for broiler chicken in early stage | |
CN103349710B (en) | Compound tilmicosin clathrate complex and preparation method thereof | |
CN101225101A (en) | Preparation technology of promoting hepatocyte growth factor solution | |
CN103432158A (en) | Polysaccharide compound for preventing and treating porcine diarrhea and application thereof | |
CN103120273B (en) | Compound feed additive capable of improving pig immunity and feed nutrient utilization rate | |
CN104031935A (en) | Intracellular expression method of large yellow croaker liver expression antibacterial peptide LEAP-2C in pichia pastoris | |
CN110545672A (en) | Method for producing fermented guar flour | |
CN107961260A (en) | Treatment, the medicament for preventing birds coliform diarrhea disease and preparation method thereof | |
CN104686804B (en) | A method of activated peptide forage additive is prepared using aquatic product leftovers | |
CN101519443A (en) | Method for inducing silkworms to produce antibacterial peptides by radiation or electric shock | |
CN105018397B (en) | A kind of bacillus subtilis bacterium culture medium and preparation method thereof | |
CN104068286B (en) | A kind of preparation method preventing and treating the Chinese herbal feed additive of duck virus hepatitis | |
CN106177692A (en) | A kind of preparation method of the Chinese herbal medicine extract preparation driving away pig Enterozoa | |
CN105732792A (en) | Yeast expressed chicken Cathelicidin antibacterial peptide as well as preparation method and application thereof | |
CN105534988B (en) | A kind of volume increase of silkworm, prevention and treatment bacterium medicine and its application | |
CN104435046B (en) | A kind of fermentation medicine for treating piglet yellow-white dysentery and preparation method thereof | |
CN105495028A (en) | Antimicrobial peptide activity feed additive for duck and preparation method of feed additive | |
KR20160085401A (en) | A feed additive including immunity induced silkworm and manufacturing method thereof | |
CN104523863B (en) | A kind of traditional Chinese medicine infusion solution and its preparation method and application | |
CN105753959A (en) | Yeast expressed chicken antibacterial peptide Cathelicidin 2 and preparation method and application thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Fan Tao Inventor after: Wu Penghao Inventor after: Zhang Yuping Inventor after: Ling Yonghua Inventor after: Zhou Yefeng Inventor after: Dai Junjun Inventor after: Fan Houwen Inventor after: Wang Chuyan Inventor after: Xiao Linzhen Inventor after: Wu Chuanhua Inventor after: Wei Guoqing Inventor after: Tian Shanfu Inventor before: Fan Tao Inventor before: Zhou Yefeng Inventor before: Dai Junjun Inventor before: Fan Houwen Inventor before: Wang Chuyan Inventor before: Xiao Linzhen Inventor before: Wu Chuanhua Inventor before: Wei Guoqing Inventor before: Tian Shanfu |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: FAN TAO ZHOU YEFENG DAI JUNJUN FAN HOUWEN WANG CHUYAN XIAO LINZHEN WU ZHUANHUA WEI GUOQING TIAN SHANFU TO: FAN TAO ZHOU YEFENG DAI JUNJUN FAN HOUWEN WANG CHUYAN XIAO LINZHEN WU ZHUANHUA WEI GUOQING TIAN SHANFU WU PENGHAO ZHANG YUPING LING YONGHUA |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information |
Inventor after: Fan Tao Inventor after: Tian Shanfu Inventor after: Wu Penghao Inventor after: Zhang Yuping Inventor after: Ling Yonghua Inventor after: Zhou Yefeng Inventor after: Dai Junjun Inventor after: Wang Yuting Inventor after: Fan Houwen Inventor after: Wang Chuyan Inventor after: Xiao Linzhen Inventor after: Wu Chuanhua Inventor after: Wei Guoqing Inventor before: Fan Tao Inventor before: Wu Penghao Inventor before: Zhang Yuping Inventor before: Ling Yonghua Inventor before: Zhou Yefeng Inventor before: Dai Junjun Inventor before: Fan Houwen Inventor before: Wang Chuyan Inventor before: Xiao Linzhen Inventor before: Wu Chuanhua Inventor before: Wei Guoqing Inventor before: Tian Shanfu |
|
CB03 | Change of inventor or designer information | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110928 Termination date: 20180331 |