CN101500583B - 含克林霉素盐酸盐的药物递送聚合物 - Google Patents

含克林霉素盐酸盐的药物递送聚合物 Download PDF

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Publication number
CN101500583B
CN101500583B CN200780029743XA CN200780029743A CN101500583B CN 101500583 B CN101500583 B CN 101500583B CN 200780029743X A CN200780029743X A CN 200780029743XA CN 200780029743 A CN200780029743 A CN 200780029743A CN 101500583 B CN101500583 B CN 101500583B
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CN
China
Prior art keywords
insert
hydrogel matrix
contact
vagina
rectum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200780029743XA
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English (en)
Chinese (zh)
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CN101500583A (zh
Inventor
J·A·哈里迪
D·A·卡尔
L·伯伊德
M·麦克格瑞格尔
A·索姆
L·凯利
M·A·利维恩斯托恩
L·M·卡瑞
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Controlled Therapeutics Scotland Ltd
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Controlled Therapeutics Scotland Ltd
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Publication of CN101500583A publication Critical patent/CN101500583A/zh
Application granted granted Critical
Publication of CN101500583B publication Critical patent/CN101500583B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200780029743XA 2006-07-12 2007-07-12 含克林霉素盐酸盐的药物递送聚合物 Expired - Fee Related CN101500583B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80714906P 2006-07-12 2006-07-12
US60/807,149 2006-07-12
PCT/GB2007/002604 WO2008007098A2 (en) 2006-07-12 2007-07-12 Drug delivery polymer with hydrochloride salt of clindamycin

Publications (2)

Publication Number Publication Date
CN101500583A CN101500583A (zh) 2009-08-05
CN101500583B true CN101500583B (zh) 2012-05-23

Family

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Family Applications (1)

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CN200780029743XA Expired - Fee Related CN101500583B (zh) 2006-07-12 2007-07-12 含克林霉素盐酸盐的药物递送聚合物

Country Status (10)

Country Link
US (1) US20080160065A1 (enExample)
EP (1) EP2037938A2 (enExample)
JP (1) JP2009542788A (enExample)
CN (1) CN101500583B (enExample)
AU (1) AU2007274081B2 (enExample)
BR (1) BRPI0713203A2 (enExample)
CA (1) CA2657533A1 (enExample)
MX (1) MX2009000053A (enExample)
RU (1) RU2444364C2 (enExample)
WO (1) WO2008007098A2 (enExample)

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GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
EP2244782A4 (en) 2008-01-25 2011-09-14 Univ Utah Res Found POLYMER WITH LINEAR ORDER RELEASE
CN102335113A (zh) * 2010-07-20 2012-02-01 杭州赛利药物研究所有限公司 克林霉素磷酸酯阴道缓释凝胶及其制备方法
US9198957B2 (en) * 2011-01-31 2015-12-01 The Trustees Of Columbia University In The City Of New York Treatment and prevention of bacterial vaginosis and Gardnerella vaginalis infections
EP3648779A4 (en) * 2017-07-07 2021-03-17 Osel, Inc. USING VAGINAL LACTOBACILLI TO IMPROVE THE SUCCESS RATE OF IN VITRO FERTILIZATION

Citations (1)

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Also Published As

Publication number Publication date
HK1137646A1 (en) 2010-08-06
WO2008007098A3 (en) 2008-03-27
JP2009542788A (ja) 2009-12-03
AU2007274081B2 (en) 2012-08-02
RU2009104695A (ru) 2010-08-20
EP2037938A2 (en) 2009-03-25
RU2444364C2 (ru) 2012-03-10
CN101500583A (zh) 2009-08-05
WO2008007098A2 (en) 2008-01-17
CA2657533A1 (en) 2008-01-17
BRPI0713203A2 (pt) 2012-04-03
US20080160065A1 (en) 2008-07-03
MX2009000053A (es) 2009-02-23
AU2007274081A1 (en) 2008-01-17

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