AU2007274081B2 - Drug delivery polymer with hydrochloride salt of clindamycin - Google Patents
Drug delivery polymer with hydrochloride salt of clindamycin Download PDFInfo
- Publication number
- AU2007274081B2 AU2007274081B2 AU2007274081A AU2007274081A AU2007274081B2 AU 2007274081 B2 AU2007274081 B2 AU 2007274081B2 AU 2007274081 A AU2007274081 A AU 2007274081A AU 2007274081 A AU2007274081 A AU 2007274081A AU 2007274081 B2 AU2007274081 B2 AU 2007274081B2
- Authority
- AU
- Australia
- Prior art keywords
- insert
- hydrogel matrix
- clindamycin
- contacting
- clindamycin hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 title claims abstract description 108
- 229960002227 clindamycin Drugs 0.000 title claims description 32
- 229920000642 polymer Polymers 0.000 title claims description 32
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 title description 3
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- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims description 5
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- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80714906P | 2006-07-12 | 2006-07-12 | |
| US60/807,149 | 2006-07-12 | ||
| PCT/GB2007/002604 WO2008007098A2 (en) | 2006-07-12 | 2007-07-12 | Drug delivery polymer with hydrochloride salt of clindamycin |
Publications (2)
| Publication Number | Publication Date |
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| AU2007274081A1 AU2007274081A1 (en) | 2008-01-17 |
| AU2007274081B2 true AU2007274081B2 (en) | 2012-08-02 |
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|---|---|---|---|
| AU2007274081A Ceased AU2007274081B2 (en) | 2006-07-12 | 2007-07-12 | Drug delivery polymer with hydrochloride salt of clindamycin |
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| Country | Link |
|---|---|
| US (1) | US20080160065A1 (enExample) |
| EP (1) | EP2037938A2 (enExample) |
| JP (1) | JP2009542788A (enExample) |
| CN (1) | CN101500583B (enExample) |
| AU (1) | AU2007274081B2 (enExample) |
| BR (1) | BRPI0713203A2 (enExample) |
| CA (1) | CA2657533A1 (enExample) |
| MX (1) | MX2009000053A (enExample) |
| RU (1) | RU2444364C2 (enExample) |
| WO (1) | WO2008007098A2 (enExample) |
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| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| EP2244782A4 (en) | 2008-01-25 | 2011-09-14 | Univ Utah Res Found | POLYMER WITH LINEAR ORDER RELEASE |
| CN102335113A (zh) * | 2010-07-20 | 2012-02-01 | 杭州赛利药物研究所有限公司 | 克林霉素磷酸酯阴道缓释凝胶及其制备方法 |
| US9198957B2 (en) * | 2011-01-31 | 2015-12-01 | The Trustees Of Columbia University In The City Of New York | Treatment and prevention of bacterial vaginosis and Gardnerella vaginalis infections |
| EP3648779A4 (en) * | 2017-07-07 | 2021-03-17 | Osel, Inc. | USING VAGINAL LACTOBACILLI TO IMPROVE THE SUCCESS RATE OF IN VITRO FERTILIZATION |
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| US3860701A (en) * | 1968-04-22 | 1975-01-14 | Searle & Co | Method for use and compositions of 11-lower alkyl steroids and drug delivery system for the controlled elution of 11-lower alkyl steroids |
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- 2007-07-12 MX MX2009000053A patent/MX2009000053A/es active IP Right Grant
- 2007-07-12 EP EP07789017A patent/EP2037938A2/en not_active Withdrawn
- 2007-07-12 RU RU2009104695/15A patent/RU2444364C2/ru not_active IP Right Cessation
- 2007-07-12 BR BRPI0713203-4A patent/BRPI0713203A2/pt not_active IP Right Cessation
- 2007-07-12 AU AU2007274081A patent/AU2007274081B2/en not_active Ceased
- 2007-07-12 CN CN200780029743XA patent/CN101500583B/zh not_active Expired - Fee Related
- 2007-07-12 CA CA002657533A patent/CA2657533A1/en not_active Abandoned
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- 2007-07-12 JP JP2009518960A patent/JP2009542788A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| HK1137646A1 (en) | 2010-08-06 |
| WO2008007098A3 (en) | 2008-03-27 |
| JP2009542788A (ja) | 2009-12-03 |
| CN101500583B (zh) | 2012-05-23 |
| RU2009104695A (ru) | 2010-08-20 |
| EP2037938A2 (en) | 2009-03-25 |
| RU2444364C2 (ru) | 2012-03-10 |
| CN101500583A (zh) | 2009-08-05 |
| WO2008007098A2 (en) | 2008-01-17 |
| CA2657533A1 (en) | 2008-01-17 |
| BRPI0713203A2 (pt) | 2012-04-03 |
| US20080160065A1 (en) | 2008-07-03 |
| MX2009000053A (es) | 2009-02-23 |
| AU2007274081A1 (en) | 2008-01-17 |
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