CN101495111A - 在联合治疗中使用免疫调节化合物的方法和组合物 - Google Patents
在联合治疗中使用免疫调节化合物的方法和组合物 Download PDFInfo
- Publication number
- CN101495111A CN101495111A CNA2007800277224A CN200780027722A CN101495111A CN 101495111 A CN101495111 A CN 101495111A CN A2007800277224 A CNA2007800277224 A CN A2007800277224A CN 200780027722 A CN200780027722 A CN 200780027722A CN 101495111 A CN101495111 A CN 101495111A
- Authority
- CN
- China
- Prior art keywords
- amino
- diketone
- pharmaceutically acceptable
- acceptable salt
- effective dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80860206P | 2006-05-26 | 2006-05-26 | |
US60/808,602 | 2006-05-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101495111A true CN101495111A (zh) | 2009-07-29 |
Family
ID=38606531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2007800277224A Pending CN101495111A (zh) | 2006-05-26 | 2007-05-24 | 在联合治疗中使用免疫调节化合物的方法和组合物 |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP2023912A2 (de) |
JP (1) | JP2009538318A (de) |
KR (1) | KR20090014393A (de) |
CN (1) | CN101495111A (de) |
AU (1) | AU2007267928A1 (de) |
CA (1) | CA2652888A1 (de) |
IL (1) | IL195412A0 (de) |
MX (1) | MX2008014912A (de) |
RU (1) | RU2426542C2 (de) |
WO (1) | WO2007139939A2 (de) |
ZA (1) | ZA200809956B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2010008220A (es) | 2008-01-29 | 2010-08-23 | Celgene Corp | Metodos que usan compuestos inmunomoduladores para modular nivel de cd59. |
WO2013142817A2 (en) * | 2012-03-23 | 2013-09-26 | Dennis Brown | Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo |
EA037667B1 (ru) | 2013-08-22 | 2021-04-28 | Ванда Фармасьютикалз Инк. | Лечение рака |
AU2014308704B2 (en) * | 2013-08-22 | 2019-10-10 | Vanda Pharmaceuticals Inc. | Multiple myeloma treatment |
US20170173083A1 (en) * | 2014-03-26 | 2017-06-22 | The Brigham And Women's Hospital, Inc. | Compositions and methods for ex vivo expansion of human hematopoietic stem/progenitor cells |
WO2015175916A1 (en) * | 2014-05-16 | 2015-11-19 | Celgene Corporation | Methods and compositions using 4-amino-2-(2,6 dioxo-piperidine-3-yl)-isoindoline-1,3-dione for treatment of cancers |
WO2023034504A1 (en) * | 2021-09-01 | 2023-03-09 | Flagship Pioneering Innovations Vi, Llc | Methods and compositions for inducing fetal hemoglobin, modulating erythroid cell lineages, and perturbing megakaryocyte lineages |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
US7498171B2 (en) * | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
CA2752140A1 (en) * | 2002-05-17 | 2003-11-27 | Celgene Corporation | Methods and compositions using 3-(4-amino-1-oxo-1,3-dihydroisoindol-1-yl)-piperidine-2,6-dione for treatment and management of renal cancer |
ZA200503240B (en) * | 2002-10-24 | 2007-11-28 | Gelgene Corp | Methods of using and compositions comprising immunodulatory compounds for treatment, modification and management of pain |
US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
US20050143420A1 (en) * | 2003-12-02 | 2005-06-30 | Moutouh-De Parseval Laure | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
US20060058311A1 (en) * | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
-
2007
- 2007-05-24 MX MX2008014912A patent/MX2008014912A/es not_active Application Discontinuation
- 2007-05-24 WO PCT/US2007/012495 patent/WO2007139939A2/en active Application Filing
- 2007-05-24 AU AU2007267928A patent/AU2007267928A1/en not_active Abandoned
- 2007-05-24 CN CNA2007800277224A patent/CN101495111A/zh active Pending
- 2007-05-24 EP EP07795353A patent/EP2023912A2/de not_active Withdrawn
- 2007-05-24 JP JP2009512164A patent/JP2009538318A/ja active Pending
- 2007-05-24 CA CA002652888A patent/CA2652888A1/en not_active Abandoned
- 2007-05-24 ZA ZA200809956A patent/ZA200809956B/xx unknown
- 2007-05-24 KR KR1020087031357A patent/KR20090014393A/ko not_active Application Discontinuation
- 2007-05-24 RU RU2008151713/15A patent/RU2426542C2/ru not_active IP Right Cessation
-
2008
- 2008-11-20 IL IL195412A patent/IL195412A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL195412A0 (en) | 2009-08-03 |
KR20090014393A (ko) | 2009-02-10 |
WO2007139939A2 (en) | 2007-12-06 |
EP2023912A2 (de) | 2009-02-18 |
CA2652888A1 (en) | 2007-12-06 |
AU2007267928A1 (en) | 2007-12-06 |
JP2009538318A (ja) | 2009-11-05 |
RU2426542C2 (ru) | 2011-08-20 |
ZA200809956B (en) | 2010-07-28 |
RU2008151713A (ru) | 2010-07-10 |
WO2007139939A3 (en) | 2008-07-03 |
MX2008014912A (es) | 2008-12-10 |
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