CN101490058A - 抗病毒剂 - Google Patents

抗病毒剂 Download PDF

Info

Publication number
CN101490058A
CN101490058A CNA2007800266569A CN200780026656A CN101490058A CN 101490058 A CN101490058 A CN 101490058A CN A2007800266569 A CNA2007800266569 A CN A2007800266569A CN 200780026656 A CN200780026656 A CN 200780026656A CN 101490058 A CN101490058 A CN 101490058A
Authority
CN
China
Prior art keywords
base
substituted
methyl
amino
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800266569A
Other languages
English (en)
Chinese (zh)
Inventor
弗朗兹·乌尔里希·施米茨
克里斯托弗·唐·罗伯茨
罗纳德·康拉德·格里菲斯
亚诺什·博詹斯基
松·明·范
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genelabs Technologies Inc
Original Assignee
Genelabs Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Technologies Inc filed Critical Genelabs Technologies Inc
Publication of CN101490058A publication Critical patent/CN101490058A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNA2007800266569A 2006-07-14 2007-07-12 抗病毒剂 Pending CN101490058A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83104006P 2006-07-14 2006-07-14
US60/831,040 2006-07-14

Publications (1)

Publication Number Publication Date
CN101490058A true CN101490058A (zh) 2009-07-22

Family

ID=38742551

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800266569A Pending CN101490058A (zh) 2006-07-14 2007-07-12 抗病毒剂

Country Status (13)

Country Link
EP (1) EP2044083A1 (ja)
JP (1) JP2009543807A (ja)
KR (1) KR20090033881A (ja)
CN (1) CN101490058A (ja)
AR (1) AR062258A1 (ja)
AU (1) AU2007272441A1 (ja)
BR (1) BRPI0714346A2 (ja)
CA (1) CA2657651A1 (ja)
MX (1) MX2009000513A (ja)
PE (1) PE20080427A1 (ja)
RU (1) RU2009105196A (ja)
TW (1) TW200813070A (ja)
WO (2) WO2008008907A2 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070049593A1 (en) 2004-02-24 2007-03-01 Japan Tobacco Inc. Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
US7659263B2 (en) 2004-11-12 2010-02-09 Japan Tobacco Inc. Thienopyrrole compound and use thereof as HCV polymerase inhibitor
WO2008137126A2 (en) 2007-05-04 2008-11-13 Vertex Pharmaceuticals Incorporated Combination therapy for the treatment of hcv infection
AR079528A1 (es) 2009-12-18 2012-02-01 Idenix Pharmaceuticals Inc Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
EP2655362A1 (en) * 2010-12-22 2013-10-30 Abbvie Inc. Hepatitis c inhibitors and uses thereof
US20120252721A1 (en) * 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
FR3008975A1 (fr) 2013-07-23 2015-01-30 Servier Lab Nouveaux derives de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2546006C1 (ru) 2014-03-07 2015-04-10 Римма Ильинична Ашкинази Противовирусное средство
US10080728B2 (en) 2015-01-20 2018-09-25 Viktor Veniaminovich Tets Hemostatic agent
US10167293B2 (en) * 2016-05-26 2019-01-01 Bayer Pharma Aktiengesellschaft [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones
CA3064733A1 (en) 2017-05-24 2018-11-29 Viktor Veniaminovich Tets Fractionated antimicrobial compositions and use thereof
US11661431B2 (en) 2021-04-16 2023-05-30 Gilead Sciences, Inc. Thienopyrrole compounds
EP4398989A1 (en) 2021-09-10 2024-07-17 Gilead Sciences, Inc. Thienopyrrole compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0210357A (pt) * 2001-06-11 2004-06-29 Shire Biochem Inc Composto e métodos para o tratamento ou a prevenção de infecções pelo flavivìrus
ZA200509590B (en) * 2003-06-04 2007-04-25 Genelabs Tech Inc Nitrogen-containing heteroaryl derivatives for the treatment of HCV-infection

Also Published As

Publication number Publication date
AR062258A1 (es) 2008-10-29
MX2009000513A (es) 2009-03-09
PE20080427A1 (es) 2008-06-11
AU2007272441A1 (en) 2008-01-17
RU2009105196A (ru) 2010-08-27
EP2044083A1 (en) 2009-04-08
CA2657651A1 (en) 2008-01-17
WO2008008912A1 (en) 2008-01-17
BRPI0714346A2 (pt) 2013-03-19
WO2008008907A3 (en) 2008-03-20
TW200813070A (en) 2008-03-16
AU2007272441A2 (en) 2009-03-19
WO2008008907A2 (en) 2008-01-17
KR20090033881A (ko) 2009-04-06
JP2009543807A (ja) 2009-12-10

Similar Documents

Publication Publication Date Title
CN101490058A (zh) 抗病毒剂
CN101103026A (zh) 用于治疗病毒感染的吲哚衍生物
CN101223161A (zh) 治疗病毒感染的杂芳基衍生物
CN101331116A (zh) N-(6-元芳香环)酰胺基抗病毒化合物
US20070032488A1 (en) 6-Membered aryl and heteroaryl derivatives for treating viruses
JP2010510245A (ja) 抗ウイルス化合物
CN101528741A (zh) 多环病毒抑制剂
TW200906826A (en) Anti-viral inhibitors and methods of use
CN108546277A (zh) 新的核苷氨基磷酸酯化合物及其应用
KR20100056462A (ko) 항바이러스 화합물, 조성물 및 용도
CN103298791B (zh) 病毒聚合酶抑制剂
US20080051384A1 (en) Antiviral agents
WO2010081149A1 (en) Anti-viral compounds, compositions, and methods of use
CN101952289A (zh) 用于治疗黄病毒感染的稠合五环衍生物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: SMITH CLINBECHIM CO.,LTD.

Free format text: FORMER OWNER: JIANYA BIOTECHNOLOGY CO.,LTD.

Effective date: 20091106

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20091106

Address after: American Pennsylvania

Applicant after: Smith Peggy DMC, company G

Address before: American California

Applicant before: Genelabs Tech Inc.

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20090722