CN101473897A - Natural anti-bacteria agent for feeding and preparation method thereof - Google Patents
Natural anti-bacteria agent for feeding and preparation method thereof Download PDFInfo
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- CN101473897A CN101473897A CNA2008100556341A CN200810055634A CN101473897A CN 101473897 A CN101473897 A CN 101473897A CN A2008100556341 A CNA2008100556341 A CN A2008100556341A CN 200810055634 A CN200810055634 A CN 200810055634A CN 101473897 A CN101473897 A CN 101473897A
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- feeding
- allicin
- inclusion
- cyclodextrin
- bacteria agent
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Abstract
The invention discloses an antimicrobial for natural feeding and a preparation method thereof. In the antimicrobial, origanum oil and garlicin are raw materials and mixed by proper ratio. The antimicrobial can strengthen animal immunity, improve animal anti-illness ability, accelerate the growth of animals, and improve the output.
Description
Technical field
The present invention relates to a kind of natural anti-bacteria agent for feeding and preparation method thereof.
Background technology
In the animal feeding process, normal because infringements such as pathogen and parasites, lead the fatal rate height, influence growth rate, aquaculture cost is increased, the early stage normal antibiotic of using is added in the feed as bacteriostatic agent, impetus has been played in development to aquaculture, but antibiotic negative effect also comes out significantly, as medicament residue, drug resistance and cross-infection problem, all these influences the quality of animal products, and can jeopardize human health by food chain indirectly.So the research of green new additive agent and the direction that use is Future Development.Along with expanding economy, the improving constantly of people's quality of life, pursuing natural, safe, non-harmful pollution-free food has become world trends and trend.Searching has become in recent years research focus to the natural additive of the useful and harmless antibiotic substitute of animal and human's class.
Origanum oil and allicin all have the report that is applied as anti-bacteria agent for feeding respectively, and the two compatibility is used and do not appeared in the newspapers as yet.
Summary of the invention
The object of the invention is to provide a kind of natural anti-bacteria agent for feeding.
Another purpose of the present invention is to provide a kind of natural anti-bacteria agent for feeding and preparation method thereof.
The present invention is implemented by the following technical programs.
Feed addictive of the present invention can be made by the raw material of following weight portion:
Origanum oil 2-10 allicin 2-10.
Wherein allicin, origanum oil can adopt conventional cyclodextrin inclusion method, make inclusion complex, and used cyclodextrin can be doubly its cyclodextrin, hydroxypropyl times its cyclodextrin.
Natural feed addictive parts by weight of raw materials of the present invention is: origanum oil 2-10 allicin 2-10, get allicin or its inclusion complex, and origanum oil or its inclusion complex, evenly mixed, add or no carrier added, make powder or granule according to a conventional method.
Allicin is the general name of main bioactive ingredients in the garlic.Has broad-spectrum antibacterial action, various biological function such as have that anti-inflammatory is hypotensive, reducing blood lipid, inhibition platelet aggregation, anti-cancer are antiviral.Allicin can obviously improve production performance, reduces the incidence of disease, reduces the death rate, increases culture benefit.Thereby can partly substitute the resistance to the action of a drug that antibiotic reduces microorganisms, livestock and poultry and healthy fish are produced wholesome effect.
Origanum oil (Oiloriganum) is the volatility oils of extracting from natural plants wild marjoram (Origanum vulgarelinn or Oregano), and its chemical composition mainly is the fragrant phenol of Thymol, Sheep's-parsley, γ-terpinenes and P-cymene; The above two have very strong antibacterial activity, and both biologies of back are precursors of synthetic Thymol and the fragrant phenol of Sheep's-parsley.
Extremely strong antibiotic, the bactericidal action of origanum oil is to realize by aldehydes matter: 1. origanum oil has stronger fat-soluble and surface-active, with the cell membrane of pathogenic microorganism very strong affinity is arranged; Phenolic compound solidifies the sex change of bacterial cell membrane structural proteins, by changing the permeability of H and K, the phenol on the cell cytoplasm film is interacted, and the dispersion of ion component causes the interior critical process of cell to be obstructed, and content runs off, thus direct pathogenic microbe killing.2. the phenols that enters in the cell body can stop mitochondria absorption oxygen and bring into play bactericidal action.3. the fragrant phenol of Thymol and Sheep's-parsley has a little intestines mucus of active effect at the epithelial epithelial layer in the ripe chamber of intestines mucus and influenced by intracellular pathogen to cause death to come off then at the intestines inner chamber, takes away slough.4. origanum oil is in the intestinal villus surface epithelial renewal in hasting of maturity chamber, and this can reduce pathogen to epithelial infection in chamber and raising nutrient absorption ability.
Origanum oil can also improve digestive enzyme activity, improves feed conversion rate, promotes growth of animal, improves immunity of organisms.
Feed addictive of the present invention uses with origanum oil, allicin compatibility, can make the growth of animal comprehensive nutrition, immunity strengthens, reduce the incidence of disease, it is very fast to grow, improve animal flesh, egg product matter, reduced and used environmental pollution that antibiotic brought and to the harm of health, feed addictive of the present invention addition in common feedstuffs is 0.3-2%.
The specific embodiment
The present invention is described further by embodiment, but is not limited to the present invention.
Embodiment 1
Get origanum oil 20g, allicin 20g, add silica 1 00g and mix evenly, make powder according to a conventional method.
Embodiment 2
Get origanum oil 20g, allicin 100g, add starch 300g and mix evenly, make powder according to a conventional method.
Embodiment 3
Get origanum oil 100g, allicin 20g, add silica 200g and mix evenly, make powder according to a conventional method.
Embodiment 4
Get origanum oil 100g, allicin 100g, add silica 400g and mix evenly, make powder according to a conventional method.
Embodiment 5
Get origanum oil 20g, allicin 20g, carry out inclusion by cyclodextrin encapsulated method, the inclusion method is as follows:
(1) get origanum oil 20g, its cyclodextrin 120g doubly, distilled water 1200ml, volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby;
(2) get allicin 20g, its cyclodextrin 120g doubly, distilled water 1200ml, volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby.
It is evenly mixed to get above-mentioned inclusion complex, makes powder or granule according to a conventional method.
Embodiment 6
Get origanum oil 18g, allicin 59g, carry out inclusion by cyclodextrin encapsulated method, the inclusion method is as follows:
(1) get origanum oil 18g, its cyclodextrin 144g doubly, distilled water 1440ml, volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby;
(2) get allicin 59g, its cyclodextrin 472g doubly, distilled water 4720ml, volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby.
It is evenly mixed to get above-mentioned inclusion complex, makes powder or granule according to a conventional method.
Embodiment 7
Get origanum oil 31g, allicin 48g, carry out inclusion by cyclodextrin encapsulated method, the inclusion method is as follows:
(1) get origanum oil 31g, hydroxypropyl is its cyclodextrin 186g doubly, distilled water 300ml, and volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby;
(2) get allicin 48g, hydroxypropyl is its cyclodextrin 288g doubly, distilled water 560ml, and volatile oil inclusion method is carried out inclusion routinely, and 40 ℃ of dryings of inclusion complex are pulverized standby.
It is evenly mixed to get above-mentioned inclusion complex, makes powder or granule according to a conventional method.
Embodiment 8
Get this bright additive and be added in the basal diet with 0.4% amount, be respectively applied in the raising of piglet, chicken, fish, the piglet incidence of disease and diarrhea rate descend 37%; The incidence of disease of chicken also descends 33%, and day egg production improves 6%, and the local flavor of egg also has clear improvement; The crucian growth rate can improve 23%.
Claims (5)
1, a kind of natural anti-bacteria agent for feeding is characterized in that being made by the raw material of following weight portion:
Origanum oil 2-10 allicin 2-10.
2, a kind of according to claim 1 natural anti-bacteria agent for feeding is characterized in that allicin can adopt conventional cyclodextrin inclusion method, makes inclusion complex.
3, a kind of according to claim 1 natural anti-bacteria agent for feeding is characterized in that origanum oil can adopt conventional cyclodextrin inclusion method, makes inclusion complex.
3,, it is characterized in that cyclodextrin can be doubly its cyclodextrin, hydroxypropyl times its cyclodextrin as claim 2,3 described a kind of natural anti-bacteria agent for feeding.
4, a kind of preparation method of a kind of natural anti-bacteria agent for feeding as claimed in claim 1, it is characterized in that: parts by weight of raw materials is: origanum oil 2-10 allicin 2-10, get allicin or its inclusion complex, origanum oil or its inclusion complex, evenly mixed, add or no carrier added, make powder or granule according to a conventional method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CNA2008100556341A CN101473897A (en) | 2008-01-04 | 2008-01-04 | Natural anti-bacteria agent for feeding and preparation method thereof |
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| CNA2008100556341A CN101473897A (en) | 2008-01-04 | 2008-01-04 | Natural anti-bacteria agent for feeding and preparation method thereof |
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| CN101473897A true CN101473897A (en) | 2009-07-08 |
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| CNA2008100556341A Pending CN101473897A (en) | 2008-01-04 | 2008-01-04 | Natural anti-bacteria agent for feeding and preparation method thereof |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731466A (en) * | 2010-02-02 | 2010-06-16 | 杨开伦 | Application of lavender essential oil as feeding antibiotic substitute in daily ration of broiler |
| CN101703156B (en) * | 2009-11-26 | 2012-04-25 | 中国水产科学研究院黑龙江水产研究所 | Fish growth promoter and preparation method thereof |
| CN102613417A (en) * | 2012-04-12 | 2012-08-01 | 海口双胞胎饲料有限公司 | Mould-proof antioxidant capable of increasing palatability of pig feed |
| CN104523822A (en) * | 2014-12-24 | 2015-04-22 | 天津市中升挑战生物科技有限公司 | Pharmaceutical composition for preventing and treating animal diarrheal diseases and preparation method of pharmaceutical composition |
| CN104664173A (en) * | 2015-03-20 | 2015-06-03 | 江门海大饲料有限公司 | Efficient environment-friendly antibiotic-free compound feed for piglets |
| CN104799046A (en) * | 2015-01-15 | 2015-07-29 | 南宁市春华农业科技有限公司 | Truogx sinensis growth accelerator and preparation method thereof |
| CN104970257A (en) * | 2015-07-20 | 2015-10-14 | 何贵明 | Antibiotic-free beef cattle growing and fattening premix and feed |
| CN105124177A (en) * | 2015-07-20 | 2015-12-09 | 何贵明 | Antibiotics-free premixed material and antibiotics-free feed for growth and fattening of mutton sheep |
| CN105341359A (en) * | 2015-12-09 | 2016-02-24 | 广州英赛特生物技术有限公司 | Application of alpha-terpilenol-beta-cyclodextrin inclusion compound in preparing animal feed additive |
| CN105475636A (en) * | 2015-11-25 | 2016-04-13 | 李德昌 | Water-soluble garlicin mixture, and preparation method and use thereof |
| CN105639120A (en) * | 2015-12-29 | 2016-06-08 | 湖南晶天科技实业有限公司 | Cyclodextrin inclusion compound containing antibiotic components, a compounding method thereof and feed additive |
| CN107410729A (en) * | 2017-05-18 | 2017-12-01 | 钱信美 | A kind of pig feed additive |
| CN109393202A (en) * | 2018-10-11 | 2019-03-01 | 北京市水产科学研究所 | A kind of mixed feed improving fancy carp survival rate |
-
2008
- 2008-01-04 CN CNA2008100556341A patent/CN101473897A/en active Pending
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101703156B (en) * | 2009-11-26 | 2012-04-25 | 中国水产科学研究院黑龙江水产研究所 | Fish growth promoter and preparation method thereof |
| CN101731466A (en) * | 2010-02-02 | 2010-06-16 | 杨开伦 | Application of lavender essential oil as feeding antibiotic substitute in daily ration of broiler |
| CN102613417A (en) * | 2012-04-12 | 2012-08-01 | 海口双胞胎饲料有限公司 | Mould-proof antioxidant capable of increasing palatability of pig feed |
| CN102613417B (en) * | 2012-04-12 | 2013-04-17 | 海口双胞胎饲料有限公司 | Mould-proof antioxidant capable of increasing palatability of pig feed |
| CN104523822A (en) * | 2014-12-24 | 2015-04-22 | 天津市中升挑战生物科技有限公司 | Pharmaceutical composition for preventing and treating animal diarrheal diseases and preparation method of pharmaceutical composition |
| CN104523822B (en) * | 2014-12-24 | 2019-02-26 | 天津市中升挑战生物科技有限公司 | A kind of pharmaceutical composition and preparation method thereof preventing and treating animal diarrhea disease |
| CN104799046A (en) * | 2015-01-15 | 2015-07-29 | 南宁市春华农业科技有限公司 | Truogx sinensis growth accelerator and preparation method thereof |
| CN104664173B (en) * | 2015-03-20 | 2017-05-24 | 江门海大饲料有限公司 | Efficient environment-friendly antibiotic-free compound feed for piglets |
| CN104664173A (en) * | 2015-03-20 | 2015-06-03 | 江门海大饲料有限公司 | Efficient environment-friendly antibiotic-free compound feed for piglets |
| CN105124177A (en) * | 2015-07-20 | 2015-12-09 | 何贵明 | Antibiotics-free premixed material and antibiotics-free feed for growth and fattening of mutton sheep |
| CN104970257A (en) * | 2015-07-20 | 2015-10-14 | 何贵明 | Antibiotic-free beef cattle growing and fattening premix and feed |
| CN105475636A (en) * | 2015-11-25 | 2016-04-13 | 李德昌 | Water-soluble garlicin mixture, and preparation method and use thereof |
| CN105341359A (en) * | 2015-12-09 | 2016-02-24 | 广州英赛特生物技术有限公司 | Application of alpha-terpilenol-beta-cyclodextrin inclusion compound in preparing animal feed additive |
| CN105639120A (en) * | 2015-12-29 | 2016-06-08 | 湖南晶天科技实业有限公司 | Cyclodextrin inclusion compound containing antibiotic components, a compounding method thereof and feed additive |
| CN107410729A (en) * | 2017-05-18 | 2017-12-01 | 钱信美 | A kind of pig feed additive |
| CN109393202A (en) * | 2018-10-11 | 2019-03-01 | 北京市水产科学研究所 | A kind of mixed feed improving fancy carp survival rate |
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Open date: 20090708 |