CN101454308B - 制备杂环衍生物的方法 - Google Patents
制备杂环衍生物的方法 Download PDFInfo
- Publication number
- CN101454308B CN101454308B CN200780019578XA CN200780019578A CN101454308B CN 101454308 B CN101454308 B CN 101454308B CN 200780019578X A CN200780019578X A CN 200780019578XA CN 200780019578 A CN200780019578 A CN 200780019578A CN 101454308 B CN101454308 B CN 101454308B
- Authority
- CN
- China
- Prior art keywords
- alkyl
- alkoxy
- substituted
- compounds
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- VWRZVBBBJDQJAZ-UHFFFAOYSA-N C[n]1c(S)nnc1-c1ccnnc1 Chemical compound C[n]1c(S)nnc1-c1ccnnc1 VWRZVBBBJDQJAZ-UHFFFAOYSA-N 0.000 description 2
- 0 CC(*1*)=**=C1NC Chemical compound CC(*1*)=**=C1NC 0.000 description 1
- ZTWKABXDEIGASN-UHFFFAOYSA-N C[n]1c(SCCCCl)nnc1-c1ccnnc1 Chemical compound C[n]1c(SCCCCl)nnc1-c1ccnnc1 ZTWKABXDEIGASN-UHFFFAOYSA-N 0.000 description 1
- JUSIWJONLKBPDU-UHFFFAOYSA-N OC(c1cnncc1)=O Chemical compound OC(c1cnncc1)=O JUSIWJONLKBPDU-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0607899.2A GB0607899D0 (en) | 2006-04-03 | 2006-04-03 | Process for preparing heterocyclic derivatives |
| GB0607899.2 | 2006-04-03 | ||
| PCT/EP2007/053118 WO2007113261A1 (en) | 2006-04-03 | 2007-03-30 | Process for preparing heterocyclic derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101454308A CN101454308A (zh) | 2009-06-10 |
| CN101454308B true CN101454308B (zh) | 2013-05-08 |
Family
ID=36581002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780019578XA Expired - Fee Related CN101454308B (zh) | 2006-04-03 | 2007-03-30 | 制备杂环衍生物的方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20070232808A1 (https=) |
| EP (1) | EP2007747B1 (https=) |
| JP (1) | JP5167242B2 (https=) |
| KR (1) | KR101411124B1 (https=) |
| CN (1) | CN101454308B (https=) |
| AU (1) | AU2007233744B2 (https=) |
| BR (1) | BRPI0710049A2 (https=) |
| CA (1) | CA2648089A1 (https=) |
| CR (1) | CR10351A (https=) |
| EA (1) | EA017304B1 (https=) |
| ES (1) | ES2443219T3 (https=) |
| GB (1) | GB0607899D0 (https=) |
| IL (1) | IL194389A0 (https=) |
| MA (1) | MA30354B1 (https=) |
| MX (1) | MX2008012876A (https=) |
| NO (1) | NO20084414L (https=) |
| WO (1) | WO2007113261A1 (https=) |
| ZA (1) | ZA200808107B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD3995C2 (ro) * | 2009-05-11 | 2010-07-31 | Государственный Университет Молд0 | Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar |
| IT201700041723A1 (it) | 2017-04-14 | 2018-10-14 | Italfarmaco Spa | Nuovi inibitori selettivi di HDAC6 |
| CN106866657A (zh) * | 2017-04-25 | 2017-06-20 | 成都倍特药业有限公司 | 一种麦角新碱的制备方法 |
| US9862675B1 (en) | 2017-07-05 | 2018-01-09 | King Fahd University Of Petroleum And Minerals | Method of N-formylating amines with a phosphonic anhydride |
| MX2023001086A (es) | 2020-08-07 | 2023-03-23 | Italfarmaco Spa | Nuevos inhibidores selectivos de histona desacetilasa 6 (hdac6) basados en oxadiazol. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020032238A1 (en) * | 2000-07-08 | 2002-03-14 | Henning Priepke | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments |
| DE10033337A1 (de) * | 2000-07-08 | 2002-01-17 | Boehringer Ingelheim Pharma | Biphenylcarbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel |
| WO2002032238A2 (de) * | 2000-10-20 | 2002-04-25 | Messmer, Ludwig | Hochverdichteter filter tow ballen |
| PE20051173A1 (es) * | 2004-02-23 | 2006-02-14 | Glaxo Group Ltd | Compuestos azabiciclico (3.1.0) hexanos como moduladores de receptores de dopamina d3 |
| GB0517193D0 (en) | 2005-08-22 | 2005-09-28 | Glaxo Group Ltd | Novel use |
-
2006
- 2006-04-03 GB GBGB0607899.2A patent/GB0607899D0/en not_active Ceased
-
2007
- 2007-03-30 CN CN200780019578XA patent/CN101454308B/zh not_active Expired - Fee Related
- 2007-03-30 CA CA002648089A patent/CA2648089A1/en not_active Abandoned
- 2007-03-30 AU AU2007233744A patent/AU2007233744B2/en not_active Ceased
- 2007-03-30 KR KR1020087026730A patent/KR101411124B1/ko not_active Expired - Fee Related
- 2007-03-30 JP JP2009503555A patent/JP5167242B2/ja not_active Expired - Fee Related
- 2007-03-30 EP EP07727590.7A patent/EP2007747B1/en active Active
- 2007-03-30 BR BRPI0710049-3A patent/BRPI0710049A2/pt not_active Application Discontinuation
- 2007-03-30 US US11/693,757 patent/US20070232808A1/en not_active Abandoned
- 2007-03-30 ES ES07727590.7T patent/ES2443219T3/es active Active
- 2007-03-30 EA EA200870405A patent/EA017304B1/ru not_active IP Right Cessation
- 2007-03-30 WO PCT/EP2007/053118 patent/WO2007113261A1/en not_active Ceased
- 2007-03-30 MX MX2008012876A patent/MX2008012876A/es active IP Right Grant
-
2008
- 2008-09-22 ZA ZA200808107A patent/ZA200808107B/xx unknown
- 2008-09-25 IL IL194389A patent/IL194389A0/en unknown
- 2008-10-07 CR CR10351A patent/CR10351A/es unknown
- 2008-10-21 NO NO20084414A patent/NO20084414L/no not_active Application Discontinuation
- 2008-10-23 MA MA31326A patent/MA30354B1/fr unknown
-
2009
- 2009-10-29 US US12/608,184 patent/US7838680B2/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| Abdellah Ech-Chahad, et al..An expeditious hydroxyamidation of carboxylic acids.《Tetrahedron Letters》.2005,第46卷第5113-5115页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100048895A1 (en) | 2010-02-25 |
| ZA200808107B (en) | 2009-10-28 |
| JP5167242B2 (ja) | 2013-03-21 |
| IL194389A0 (en) | 2009-08-03 |
| EP2007747A1 (en) | 2008-12-31 |
| CR10351A (es) | 2008-10-29 |
| EA200870405A1 (ru) | 2009-04-28 |
| EA017304B1 (ru) | 2012-11-30 |
| KR20080108328A (ko) | 2008-12-12 |
| AU2007233744B2 (en) | 2012-09-06 |
| AU2007233744A1 (en) | 2007-10-11 |
| CN101454308A (zh) | 2009-06-10 |
| NO20084414L (no) | 2008-10-28 |
| US20070232808A1 (en) | 2007-10-04 |
| WO2007113261A1 (en) | 2007-10-11 |
| GB0607899D0 (en) | 2006-05-31 |
| BRPI0710049A2 (pt) | 2011-08-02 |
| ES2443219T3 (es) | 2014-02-18 |
| EP2007747B1 (en) | 2013-11-20 |
| MA30354B1 (fr) | 2009-04-01 |
| CA2648089A1 (en) | 2007-10-11 |
| KR101411124B1 (ko) | 2014-06-25 |
| US7838680B2 (en) | 2010-11-23 |
| JP2009532428A (ja) | 2009-09-10 |
| MX2008012876A (es) | 2008-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2019201352B2 (en) | Bromodomain inhibitors | |
| EP3152212B9 (en) | Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof | |
| KR100274104B1 (ko) | 포스포디에스테라제 억제제로서의 피리도[2,3-d]피리미딘 유도체, 이의 제조방법 및 이를 함유하는 약제학적 조성물 | |
| ES2202647T3 (es) | Derivados de la piridina-2-il-metilamina, su procedimiento de preparacion y su utilizacion como medicamentos. | |
| US11485738B2 (en) | Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors | |
| JP2002537298A (ja) | ピリジン化合物およびその医薬用途 | |
| TR201808112T4 (tr) | Kinaz inhibitörleri olarak heterosiklik amidler. | |
| JPWO2005061490A1 (ja) | Ｈｉｖインテグラーゼ阻害活性を有するヒドロキシピリミジノン誘導体 | |
| JPH11513679A (ja) | 薬剤活性キナゾリン化合物 | |
| CN101454308B (zh) | 制备杂环衍生物的方法 | |
| EP3704106A1 (en) | Alkene compounds as farnesoid x receptor modulators | |
| TW202214602A (zh) | Il-17之小分子調節劑 | |
| AU619111B2 (en) | Antirhinoviral (thio) morpholinyl and piperazinyl alkylphenol ethers | |
| WO2008085117A1 (en) | Pyridine compounds and their use as p2y12 antagonists. | |
| WO2014089140A1 (en) | Process for making reverse transcriptase inhibitors | |
| EP4578857A1 (en) | Cryptolepine salt derivative, and preparation method therefor and use thereof | |
| JP2025505830A (ja) | Ｒａｄ５１阻害剤としての新規二環式化合物 | |
| MX2008016548A (es) | Nuevos analogos de piridina. | |
| Gohil et al. | Synthesis of Substituted 1, 2, 4-Triazole Containing Novel Small Molecules by Using Microwave | |
| HK40080347A (en) | Bromodomain inhibitors | |
| MXPA05006588A (es) | Compuestos de pirazol como derivados antagonistas del receptor de la integrina. | |
| RU2557659C1 (ru) | Способ получения амидразонов 4-r-1,2,5-оксадиазол-3-карбоновой кислоты | |
| CN113943281A (zh) | 异恶唑嘧啶衍生物的合成方法及其应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130508 Termination date: 20170330 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |