CN101453991B - 应用滚压机制备多颗粒的方法 - Google Patents

应用滚压机制备多颗粒的方法 Download PDF

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Publication number
CN101453991B
CN101453991B CN2007800195775A CN200780019577A CN101453991B CN 101453991 B CN101453991 B CN 101453991B CN 2007800195775 A CN2007800195775 A CN 2007800195775A CN 200780019577 A CN200780019577 A CN 200780019577A CN 101453991 B CN101453991 B CN 101453991B
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CN
China
Prior art keywords
multiparticulates
small pieces
roller
mixture
roller bearing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007800195775A
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English (en)
Chinese (zh)
Other versions
CN101453991A (zh
Inventor
P·G·里加西-迪特里克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
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Novartis AG
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Publication date
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Publication of CN101453991A publication Critical patent/CN101453991A/zh
Application granted granted Critical
Publication of CN101453991B publication Critical patent/CN101453991B/zh
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN2007800195775A 2006-06-07 2007-06-05 应用滚压机制备多颗粒的方法 Expired - Fee Related CN101453991B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80410406P 2006-06-07 2006-06-07
US60/804,104 2006-06-07
PCT/EP2007/055539 WO2007141282A2 (en) 2006-06-07 2007-06-05 Process for making multiparticulates using a roller compactor

Publications (2)

Publication Number Publication Date
CN101453991A CN101453991A (zh) 2009-06-10
CN101453991B true CN101453991B (zh) 2012-02-01

Family

ID=38656607

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800195775A Expired - Fee Related CN101453991B (zh) 2006-06-07 2007-06-05 应用滚压机制备多颗粒的方法

Country Status (11)

Country Link
US (1) US8329201B2 (enExample)
EP (1) EP2029113A2 (enExample)
JP (2) JP2009539797A (enExample)
KR (1) KR20090015954A (enExample)
CN (1) CN101453991B (enExample)
AU (1) AU2007255392B2 (enExample)
BR (1) BRPI0712255A2 (enExample)
CA (1) CA2649372A1 (enExample)
MX (1) MX2008015487A (enExample)
RU (1) RU2451504C2 (enExample)
WO (1) WO2007141282A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014204706B4 (de) * 2014-03-13 2019-06-06 Siemens Healthcare Gmbh Empfänger-Baugruppe eines bildgebenden Magnetresonanz-Systems und ein bildgebendes Magnetresonanz-System
RU2576438C1 (ru) * 2014-09-17 2016-03-10 Открытое акционерное общество "Корпорация "Росхимзащита" (ОАО "Корпорация "Росхимзащита") Способ получения гранулированного регенеративного продукта с применением вальцового компактора
JP6615595B2 (ja) * 2015-12-04 2019-12-04 株式会社ダイセル 口腔内崩壊性シート状製剤
IL301683B2 (en) 2017-05-17 2025-02-01 Massachusetts Inst Technology Self-healing systems and related components and methods
EP3793667A1 (en) 2018-05-17 2021-03-24 Massachusetts Institute of Technology Systems for electrical stimulation
US11541216B2 (en) 2019-11-21 2023-01-03 Massachusetts Institute Of Technology Methods for manufacturing tissue interfacing components
WO2025003114A1 (en) 2023-06-26 2025-01-02 Basf Se Compaction roller and method for manufacturing agglomerates

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0602014A1 (en) * 1989-05-26 1994-06-15 Terumo Kabushiki Kaisha Preparation for blood dialysis and method for production thereof
US5332519A (en) * 1992-05-22 1994-07-26 Church & Dwight Co., Inc. Detergent composition that dissolves completely in cold water, and method for producing the same
CN1217011A (zh) * 1996-03-29 1999-05-19 普罗克特和甘保尔公司 热量胞

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5342474B2 (enExample) * 1975-02-27 1978-11-11
JPS61283500A (ja) * 1985-06-10 1986-12-13 Kobe Steel Ltd 粉粒体造塊用セパレ−タ
JP3025901B2 (ja) * 1990-10-03 2000-03-27 コニカ株式会社 硝酸塩の圧縮造粒方法
DE19853985A1 (de) * 1998-11-23 2000-05-25 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
AU6488700A (en) * 1999-06-15 2001-01-02 Grain Processing Corporation Compacted starch hydrolysate product with improved handling characteristics and reduced tendency to become sticky
JP4903334B2 (ja) * 1999-10-13 2012-03-28 ノヴォ ノルディスク アー／エス 細長の剤形を製造する方法
AR034813A1 (es) * 2001-07-20 2004-03-17 Novartis Ag Composiciones farmaceuticas y uso de las mismas
JP4100964B2 (ja) * 2002-05-30 2008-06-11 ツムラ ライフサイエンス株式会社 ブリケット製剤およびその製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0602014A1 (en) * 1989-05-26 1994-06-15 Terumo Kabushiki Kaisha Preparation for blood dialysis and method for production thereof
US5332519A (en) * 1992-05-22 1994-07-26 Church & Dwight Co., Inc. Detergent composition that dissolves completely in cold water, and method for producing the same
CN1217011A (zh) * 1996-03-29 1999-05-19 普罗克特和甘保尔公司 热量胞

Also Published As

Publication number Publication date
CN101453991A (zh) 2009-06-10
RU2451504C2 (ru) 2012-05-27
JP2013253093A (ja) 2013-12-19
MX2008015487A (es) 2009-01-12
US8329201B2 (en) 2012-12-11
WO2007141282A3 (en) 2008-08-07
EP2029113A2 (en) 2009-03-04
AU2007255392A1 (en) 2007-12-13
AU2007255392B2 (en) 2011-09-22
JP2009539797A (ja) 2009-11-19
CA2649372A1 (en) 2007-12-13
BRPI0712255A2 (pt) 2012-01-17
RU2008152184A (ru) 2010-07-20
WO2007141282A2 (en) 2007-12-13
KR20090015954A (ko) 2009-02-12
US20100003318A1 (en) 2010-01-07

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C56 Change in the name or address of the patentee

Owner name: NOVARTIS CO., LTD.

Free format text: FORMER NAME: NOVARTIS AG

CP01 Change in the name or title of a patent holder

Address after: Basel

Patentee after: Novartis Ag

Address before: Basel

Patentee before: Novartis AG

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120201

Termination date: 20140605