CN101384266B - 肌醇六磷酸和锌的固定剂量结合物 - Google Patents

肌醇六磷酸和锌的固定剂量结合物 Download PDF

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Publication number
CN101384266B
CN101384266B CN200780005915XA CN200780005915A CN101384266B CN 101384266 B CN101384266 B CN 101384266B CN 200780005915X A CN200780005915X A CN 200780005915XA CN 200780005915 A CN200780005915 A CN 200780005915A CN 101384266 B CN101384266 B CN 101384266B
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zinc
hydroxyapatite
conjugate
phytic acid
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Expired - Fee Related
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Chinese (zh)
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CN101384266A (zh
Inventor
F·格拉斯弗雷谢达什
J·佩雷罗贝斯塔德
B·爱森阿门瓜尔
P·桑切斯科尔特斯
R·M·普利特阿尔米拉利
A·科斯塔保扎
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Universitat de les Illes Balears
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Universitat de les Illes Balears
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
CN200780005915XA 2006-02-17 2007-02-14 肌醇六磷酸和锌的固定剂量结合物 Expired - Fee Related CN101384266B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ESP-200600377 2006-02-17
ES200600377A ES2280136B1 (es) 2006-02-17 2006-02-17 Asociacion a dosis fija de fitato y zinc.
ESP200600377 2006-02-17
PCT/EP2007/051413 WO2007093611A1 (en) 2006-02-17 2007-02-14 Fixed-dose association of phytate and zinc

Publications (2)

Publication Number Publication Date
CN101384266A CN101384266A (zh) 2009-03-11
CN101384266B true CN101384266B (zh) 2013-03-20

Family

ID=38007006

Family Applications (1)

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CN200780005915XA Expired - Fee Related CN101384266B (zh) 2006-02-17 2007-02-14 肌醇六磷酸和锌的固定剂量结合物

Country Status (18)

Country Link
US (2) US8377908B2 (enExample)
EP (1) EP1984001B1 (enExample)
JP (2) JP5554499B2 (enExample)
CN (1) CN101384266B (enExample)
AT (1) ATE516035T1 (enExample)
AU (1) AU2007216453B2 (enExample)
BR (1) BRPI0707008A2 (enExample)
CA (1) CA2641216C (enExample)
CY (1) CY1111913T1 (enExample)
DK (1) DK1984001T3 (enExample)
ES (1) ES2280136B1 (enExample)
MX (1) MX2008010502A (enExample)
NO (1) NO341286B1 (enExample)
PL (1) PL1984001T3 (enExample)
PT (1) PT1984001E (enExample)
RU (1) RU2415673C2 (enExample)
SI (1) SI1984001T1 (enExample)
WO (1) WO2007093611A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2280136B1 (es) * 2006-02-17 2008-08-16 Universitat De Les Illes Balears Asociacion a dosis fija de fitato y zinc.
AU2011373141B2 (en) * 2011-07-12 2015-12-10 The Procter & Gamble Company Oral care compositions comprising phytic acid
ES2486441B1 (es) * 2014-04-02 2015-06-11 Universitat De Les Illes Balears Preparaciones combinadas de acidificantes urinarios e inhibidores de la cristalización y su aplicación para el tratamiento o prevención de la litiasis renal fosfática o inducida por fosfato cálcico
BR112017012809B1 (pt) 2014-12-26 2020-09-24 Colgate-Palmolive Company Composição para higiene bucal e uso de um complexo de polifosfato de zinco solúvel na preparação da mesma
DE102016013737A1 (de) 2016-11-17 2018-05-17 WindplusSonne GmbH Hexahydroxycyclohexanhexaphosphorsäureestersalze zur Behandlung von Kalzinose sowie diätische Lebensmittel mit Hexahydroxycyclohexanhexaphosphorsäureestersalzen als Zusatzstoffe
CN108444985B (zh) * 2018-04-25 2021-02-02 山西省食品药品检验所(山西省药品包装材料监测中心) 一种肾精子icp-ms鉴别方法及应用
US20210347793A1 (en) * 2018-09-18 2021-11-11 Inositec Ag Calcium oxalate crystallization inhibitors for renal disorders
US11633416B1 (en) 2020-03-06 2023-04-25 Arcus Biosciences, Inc. Oral formulations of CD73 compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259316A (en) * 1979-07-31 1981-03-31 Lion Corporation Oral composition for caries prophylaxis
US5300289A (en) * 1991-12-10 1994-04-05 The Dow Chemical Company Phytate antimicrobial compositions in oral care products
CN1593376A (zh) * 2004-06-24 2005-03-16 江西航天日用化工发展有限责任公司 可去除烟黄斑牙垢的复方牙膏及其制备方法

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Publication number Priority date Publication date Assignee Title
US3934001A (en) * 1965-12-07 1976-01-20 Lever Brothers Company Oral compositions containing germicidally active plastic powders
NL149701C (nl) 1965-12-08 1981-05-15 Procter & Gamble Werkwijze voor het bereiden van een tegen tandsteen werkzaam tandverzorgingsmiddel, dat als werkzaam bestanddeel een fosfonzuurderivaat bevat, alsmede gevormd tandverzorgingsmiddel.
US3934002A (en) 1972-06-30 1976-01-20 The Procter & Gamble Company Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies
US4215105A (en) 1978-10-27 1980-07-29 Colgate-Palmolive Company Anticalculus oral composition
JPS5846483B2 (ja) * 1979-09-20 1983-10-17 ライオン株式会社 口腔用組成物
JPS6043322B2 (ja) * 1979-09-05 1985-09-27 ライオン株式会社 口腔用組成物
US4515772A (en) * 1982-06-22 1985-05-07 The Procter & Gamble Company Oral compositions
US4808409A (en) 1984-08-16 1989-02-28 Board Of Trustees, University Of Illinois Low cariogenic sweetening agents
JPS6229526A (ja) * 1985-08-01 1987-02-07 Wakamoto Pharmaceut Co Ltd 高カルシウム尿症の治療及び予防剤
US4808401A (en) * 1985-09-13 1989-02-28 Colgate-Palmolive Company Anticalculus oral composition
US4627977A (en) 1985-09-13 1986-12-09 Colgate-Palmolive Company Anticalculus oral composition
JPH0729909B2 (ja) * 1986-11-28 1995-04-05 ライオン株式会社 口腔用組成物
JPH01305033A (ja) * 1988-06-01 1989-12-08 Sanwa Kagaku Kenkyusho Co Ltd 循環改善剤及び循環改善機能性食品並びにし好品
ES2007238A6 (es) * 1988-06-17 1989-06-01 Univ Illes Balears Procedimiento para la preparacion de fitato-zn (ii)>
US5286479A (en) * 1991-12-10 1994-02-15 The Dow Chemical Company Oral compositions for suppressing mouth odors
CN1102978A (zh) * 1993-11-23 1995-05-31 姚焕新 多功能牙膏
JPH08104635A (ja) * 1994-10-06 1996-04-23 Ichimaru Pharcos Co Ltd フィチン酸亜鉛を有効成分とする外用製剤
JPH10182383A (ja) * 1996-12-24 1998-07-07 Lion Corp 口腔用組成物
IT1306133B1 (it) * 1999-04-22 2001-05-30 Sigma Tau Healthscience Spa Composizione comprendente una carnitina ed un inositolfosfato, utilequale integratore dietetico o medicamento.
JP2004065249A (ja) * 2002-06-13 2004-03-04 Fumio Hara フィチン酸、イノシトールおよびナイアシンの富化方法、食品の製造方法、並びに食品
ES2232302B1 (es) * 2003-11-07 2006-08-01 Universitat De Les Illes Balears Myo-inositol hexafosfato para uso topico.
BRPI0619389A2 (pt) * 2005-11-29 2011-10-04 Procter & Gamble composição dentifrìcia compreendendo um sistema aglutinante que compreende material de argila hidrofìlica
CA2634758A1 (en) * 2005-12-20 2007-07-05 The Procter & Gamble Company Oral care compositions comprising zinc and phytate
ES2280136B1 (es) * 2006-02-17 2008-08-16 Universitat De Les Illes Balears Asociacion a dosis fija de fitato y zinc.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259316A (en) * 1979-07-31 1981-03-31 Lion Corporation Oral composition for caries prophylaxis
US5300289A (en) * 1991-12-10 1994-04-05 The Dow Chemical Company Phytate antimicrobial compositions in oral care products
CN1593376A (zh) * 2004-06-24 2005-03-16 江西航天日用化工发展有限责任公司 可去除烟黄斑牙垢的复方牙膏及其制备方法

Non-Patent Citations (2)

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Felix Grases,等.Phytate (Myo-inositol hexakisphosphate) inhibits cardiovascular calcifications in rats.《Frontiers in Bioscience》.2006,第11卷(第1期),136-142. *

Also Published As

Publication number Publication date
JP2014139182A (ja) 2014-07-31
RU2415673C2 (ru) 2011-04-10
PL1984001T3 (pl) 2012-02-29
US9144578B2 (en) 2015-09-29
SI1984001T1 (sl) 2011-12-30
EP1984001B1 (en) 2011-07-13
PT1984001E (pt) 2011-10-18
MX2008010502A (es) 2008-10-23
ATE516035T1 (de) 2011-07-15
ES2280136B1 (es) 2008-08-16
US20090035232A1 (en) 2009-02-05
US20140056994A1 (en) 2014-02-27
AU2007216453B2 (en) 2012-09-27
RU2008138358A (ru) 2010-03-27
JP5554499B2 (ja) 2014-07-23
JP2009526818A (ja) 2009-07-23
CA2641216A1 (en) 2007-08-23
ES2280136A1 (es) 2007-09-01
JP5908933B2 (ja) 2016-04-26
DK1984001T3 (da) 2011-11-07
CA2641216C (en) 2014-04-15
CN101384266A (zh) 2009-03-11
BRPI0707008A2 (pt) 2011-04-12
EP1984001A1 (en) 2008-10-29
US8377908B2 (en) 2013-02-19
WO2007093611A1 (en) 2007-08-23
NO341286B1 (no) 2017-10-02
AU2007216453A1 (en) 2007-08-23
NO20083901L (no) 2008-09-11
CY1111913T1 (el) 2015-11-04

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Granted publication date: 20130320