CN101374833B - 新型吡喃酮-吲哚衍生物及其制备方法 - Google Patents
新型吡喃酮-吲哚衍生物及其制备方法 Download PDFInfo
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77332206P | 2006-02-15 | 2006-02-15 | |
| US60/773,322 | 2006-02-15 | ||
| PCT/IB2007/000330 WO2007093880A2 (en) | 2006-02-15 | 2007-02-13 | Novel pyrone-indole derivatives and process for their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101374833A CN101374833A (zh) | 2009-02-25 |
| CN101374833B true CN101374833B (zh) | 2012-06-27 |
Family
ID=38283075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800039654A Active CN101374833B (zh) | 2006-02-15 | 2007-02-13 | 新型吡喃酮-吲哚衍生物及其制备方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US7635710B2 (enExample) |
| EP (1) | EP1991541B1 (enExample) |
| JP (1) | JP5248332B2 (enExample) |
| KR (1) | KR101207736B1 (enExample) |
| CN (1) | CN101374833B (enExample) |
| AU (1) | AU2007216226B2 (enExample) |
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Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| CN103319467B (zh) * | 2013-06-15 | 2015-10-14 | 湖南科技大学 | 一种4-[5-羟基-4-吡喃酮-2-基亚甲氨基]-3-巯基-1,2,4-三唑化合物及用途 |
| US9637451B2 (en) | 2014-01-14 | 2017-05-02 | Astellas Pharma Inc. | Indole compound |
| RU2561045C1 (ru) * | 2014-07-15 | 2015-08-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кубанский государственный университет" (ФГБОУ ВПО "КубГУ") | Нейропротекторное фармакологическое средство |
| US9567510B2 (en) | 2014-09-11 | 2017-02-14 | Halliburton Energy Services, Inc. | Cyanamide-based carbon dioxide and/or hydrogen sulfide scavengers and methods of use in subterranean operations |
| KR102385665B1 (ko) * | 2015-02-25 | 2022-04-14 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 질환을 치료하기 위한 5ht 작용제 |
| SG11201901449XA (en) * | 2016-08-23 | 2019-03-28 | Neurim Pharmaceuticals 1991 Ltd | Method for treating pruritus and/or itch |
| MX2020001342A (es) | 2017-08-04 | 2020-08-31 | Ovid Therapeutics Inc | Uso de gaboxadol en el tratamiento contra diabetes y afecciones relacionadas. |
| CN111683976B (zh) | 2018-02-05 | 2022-11-18 | 生物辐射实验室股份有限公司 | 具有阴离子交换-疏水混合模式配体的色谱树脂 |
| MX2021003302A (es) | 2018-09-20 | 2021-05-13 | Ovid Therapeutics Inc | Uso de gaboxadol para el tratamiento del sindrome de tourette, los tics y la tartamudez. |
| MX2021007224A (es) | 2018-12-17 | 2021-09-23 | Ovid Therapeutics Inc | Uso de gaboxadol para el tratamiento del trastorno del sue?o vigilia que no es de 24 horas. |
| EP4149458A4 (en) | 2020-05-11 | 2024-06-05 | B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University | COMPOSITIONS OF TRYPTOPHOL DERIVATIVES AND 4-ETHYL-PHENOL DERIVATIVES, AND METHODS OF USE THEREOF |
| CN117377777A (zh) | 2021-05-11 | 2024-01-09 | 纽瑞姆制药（1991）有限公司 | 诊断和治疗具有2号染色体2:107,510,000-107,540,000基因座单核苷酸多态性受试者的方法 |
| IL321429A (en) | 2023-01-13 | 2025-08-01 | Neurim Pharmaceuticals 1991 Ltd | Piromelatine for treating parasomnias associated with loss of rem sleep atonia |
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| CN1352545A (zh) * | 1999-05-27 | 2002-06-05 | 纽里姆药品(1991)有限公司 | 吲哚衍生物 |
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| CA222247A (en) | 1922-08-15 | Hubert Rogers Reginald | Pocket container for confections | |
| IT1196849B (it) | 1986-02-16 | 1988-11-25 | Rotta Research Lab | Nuovi derivati degli acidi 5 pentilammino 5 oxo pentaoico e 4 pentilammino 4 oxo butanoico ad attivita antagonista della colecistochinina e procedimento per la loro preparazione |
| WO1992007829A1 (en) | 1990-11-02 | 1992-05-14 | The Upjohn Company | Indole-3-methanamines useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents |
| US5789440A (en) * | 1993-11-19 | 1998-08-04 | Warner-Lambert Company | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
| WO1997035565A1 (en) * | 1996-03-27 | 1997-10-02 | Toray Industries, Inc. | Ketone derivatives and medicinal use thereof |
| CA2406271A1 (en) * | 2000-04-18 | 2001-10-25 | Cytovia, Inc. | Substituted 1,4-thiazepine and analogs and their use as activators of caspases |
| PE20060303A1 (es) | 2004-06-23 | 2006-05-19 | Wyeth Corp | Metabolitos de indolilalquilamina como ligandos de 5-hidroxitriptamina-6 |
| US7834050B2 (en) * | 2006-03-29 | 2010-11-16 | Duke University | Small molecule insulin mimetics absent quinones |
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| CN1352545A (zh) * | 1999-05-27 | 2002-06-05 | 纽里姆药品(1991)有限公司 | 吲哚衍生物 |
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