CN101361863B - Mulberry cypress hair growth liniment and preparation method thereof - Google Patents
Mulberry cypress hair growth liniment and preparation method thereof Download PDFInfo
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- CN101361863B CN101361863B CN2008101963152A CN200810196315A CN101361863B CN 101361863 B CN101361863 B CN 101361863B CN 2008101963152 A CN2008101963152 A CN 2008101963152A CN 200810196315 A CN200810196315 A CN 200810196315A CN 101361863 B CN101361863 B CN 101361863B
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Abstract
The invention discloses a mulberry-amboyna bark liniment for hair restore. The main medical compositions of the active ingredient of the raw materials are winter mulberry leaf and phellodendron and therefore the invention is called mulberry-amboyna bark liniment for hair restore; the mulberry-amboyna bark liniment also comprises minor portions of vitex trifolia fruit, rhizoma cimicifugae, herba celiptae, kochia scoparia fruit and other traditional Chinese herbs; the clear and apparent medical liquid which is just the mulberry-amboyna bark liniment is obtained after the soaking in medical alcohol and filtering of the compositions. The mulberry-amboyna bark liniment has the advantages of scientific formula, evident treatment effect, easy usage, low price but no toxic side effect and the like. The liniment can be repeatedly applied to the head part needing hair restore for two to three times per day. Generally the pore applied with the liniment can be observed to arise 4 days after the application and the new hair can grow gradually. In addition, the liniment can eliminate fat, dandruff and itch as well as controlling the hair loss.
Description
Technical field
The present invention relates to a kind of lotion that putting on the skin of alopecia is coated with for the treatment of, particularly a kind of externally-applied liniment that helps hair growth promoting with medical alcohol immersion being used for the treatment of alopecia of Chinese medicine.
Background technology
Alopecia is commonly encountered diseases, the frequently-occurring disease in the department of dermatologry, comprises seborrheic alopecia, alopecia areata, male pattern alopecia etc.Though primary disease is direct life threatening not, the lighter often is the important behaviour of sub-health state, and unusual external reflection takes place weight person's senilism or body physiological index often, has seriously influenced the external attractive in appearance of people.Pursue today of quality of life day by day people, alopecia has brought great psychic pain and mental maladjustment to extensive patients.
Western medical treatment alopecia method commonly used has hormone, contact sensitizing agent, photochemotherapy etc., and these therapies all have effect in various degree, and the figure for taking stopgap measures.
The many from ancient times to the present check weighings of Chinese traditional treatment alopecia nourish in sweet temperature.Once 132 first ancient prescriptions of treatment alopecia before clear had been made statistical analysis, what medicine frequency was the highest is that tonic 87%, 10% is a drug for invigorating blood circulation and eliminating stasis, and all the other are for medicine such as dispeling the wind.To the medicine statistics of 176 prescriptions of nearly 10 years documents treatment alopecia, what medicine frequency was the highest also be tonic 79%, next drug for invigorating blood circulation and eliminating stasis 13%, and antipyretic 5% is the medicine etc. that dispels the wind once more.Common drug ZHANGGUANG 101 hair regenerating tonic, tonifying kidney and hairs ball, YANGXUE SHENGFA JIAONANG, the precious hair tonic of cloud etc. also bias toward sweet temperature nourishing more clinically at present, existing ancient times name side, the new side of self-control is also arranged, though can obtain certain short term effect, but the hair loss patient that causes for causes of disease such as heat stagnation, stagnation of phlegm, worm-eatens is poor effect then, has tangible limitation.
Summary of the invention
Purpose of the present invention mainly is in order to overcome the weak point of said medicine, provide a kind of the cause of disease such as heat stagnation, stagnation of phlegm, worm-eaten is caused hair loss patient have obvious therapeutic effect easy to use, sterilizing ability strong, have no side effect, to the mulberry cypress hair growth liniment of skin vacuum response.
Another object of the present invention provides the preparation method of this liniment.
Liniment of the present invention is mainly selected dispelling wind and heat pathogens for use, the winter folium mori of removing heat from blood long hair; Clearing away heat-fire, the parasiticidal Cortex Phellodendri of dampness removing to stop itchin; Frivolous liter looses, the hot and suffocating Rhizoma Cimicifugae of light saturating the whole body; Dispelling wind and heat pathogens, the Fructus Viticis of clear sharp head's energy long hair; Go into the kidney nourishing YIN and the hair of growing can be gone into blood again, be the Herba Ecliptae of the product of cooling blood for hemostasis; Long-pending heat in the peeling skin is removed the skin exogenous damp and is itched, and dermatophytes is had the Fructus Kochiae of good bacteriostasis.Extract its effective ingredient, make each efficacy of drugs produce synergism, thereby the alopecia that causes because of heat stagnation, stagnation of phlegm, worm-eaten is had notable therapeutic effect.
The consumption that liniment of the present invention is formed draws through groping in a large number to sum up, and the main ingredient in its raw materials of effective components all has curative effect preferably in the following weight parts scope: 10~30 parts of winter folium moris, 10~50 parts of Cortex Phellodendris, 15~40 parts of Fructus Viticises, 5~15 parts of Rhizoma Cimicifugaes, 15~40 parts of Herba Ecliptaes, 10~50 parts of the Fructus Kochiae, medical alcohol are an amount of.
Be preferably: 20~25 parts of winter folium moris, 30~35 parts of Cortex Phellodendris, 25~30 parts of Fructus Viticises, 10~15 parts of Rhizoma Cimicifugaes, 20~35 parts of Herba Ecliptaes, 25~40 parts of the Fructus Kochiae, ethanol are an amount of.
The preferred manufacturing procedure of liniment of the present invention comprises the following steps:
A) take by weighing each crude drug: winter folium mori, Cortex Phellodendri, Fructus Viticis, Rhizoma Cimicifugae, Herba Ecliptae, the Fructus Kochiae, standby;
B) Fructus Viticis, the Fructus Kochiae of described weight proportion are wrapped with the cloth of sterilizing respectively and be placed in first container, add an an amount of alcohol-pickled week;
C) winter folium mori, Cortex Phellodendri, Rhizoma Cimicifugae, the Herba Ecliptae of described weight proportion are cleaned respectively and be placed in second container, add an an amount of alcohol-pickled week;
D) medicinal liquid in above-mentioned two containers and medicinal residues are merged to soak 10 to 20 days again in the container after, with the whole filterings of medicinal residues, a night is left standstill in medicinal liquid cold preservation, filter with 100 mesh sieves, refilter with the medicinal liquid filter paper at last, the as clear as crystal medicinal liquid that obtains is respectively charged into bottle, is mulberry cypress hair growth liniment of the present invention.
Liniment of the present invention, mainly be to have miscellaneous pathological factor at present clinical hair loss patient majority---" hot and suffocating " " worm-eaten " and drafting, clinical effectiveness reacts this side the heat radiation removing heat from blood, effect such as killing parasites for relieving itching, growing and blacking hair, through laboratory observation, can promote local blood circulation, activate hair follicle cell, antiphlogistic antibacterial promotes hair regeneration.Can be used for treating alopecia areata, alopecia totalis, alopecia universalis and withered, also can be used for poliosis, the dandruff scalp pomade increases, and more can prevent alopecia.Have scientific formulation, evident in efficacy, easy to use, low price, advantage such as have no side effect.During use, be stained with liniment with absorbent cotton and put on the skin repeatedly in alopecia place and be coated with, can see the pore projection after general 4 days every day 2~3 times, New Development grows, and the fat that can disappear, dandruff removing, antipruritic, more can control recurrence.
The specific embodiment
Liniment of the present invention can be made with effective component extracting in the following bulk drugs:
1,10 parts of winter folium moris, 10 parts of Cortex Phellodendris, 15 parts of Fructus Viticises, 5 parts of Rhizoma Cimicifugaes, 15 parts of Herba Ecliptaes, 10 parts of the Fructus Kochiae.
2,30 parts of winter folium moris, 50 parts of Cortex Phellodendris, 40 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 40 parts of Herba Ecliptaes, 50 parts of the Fructus Kochiae.
3,20 parts of winter folium moris, 30 parts of Cortex Phellodendris, 25 parts of Fructus Viticises, 10 parts of Rhizoma Cimicifugaes, 30 parts of Herba Ecliptaes, 30 parts of the Fructus Kochiae.
4,25 parts of winter folium moris, 35 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
5,20 parts of winter folium moris, 35 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
6,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
7,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
8,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 25 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
9,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 10 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
10,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 30 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
11,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 30 parts of the Fructus Kochiae.
12,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
13,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 20 parts of Herba Ecliptaes, 40 parts of the Fructus Kochiae.
14,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 20 parts of Herba Ecliptaes, 25 parts of the Fructus Kochiae.
15,25 parts of winter folium moris, 30 parts of Cortex Phellodendris, 30 parts of Fructus Viticises, 15 parts of Rhizoma Cimicifugaes, 35 parts of Herba Ecliptaes, 25 parts of the Fructus Kochiae.
16,20 parts of winter folium moris, 30 parts of Cortex Phellodendris, 25 parts of Fructus Viticises, 10 parts of Rhizoma Cimicifugaes, 30 parts of Herba Ecliptaes, 30 parts of the Fructus Kochiae.
In sum, bulk drugs all is effective between 10~50 parts of 10~30 parts of winter folium moris, 10~50 parts of Cortex Phellodendris, 15~40 parts of Fructus Viticises, 5~15 parts of Rhizoma Cimicifugaes, 15~40 parts of Herba Ecliptaes, the Fructus Kochiae.
The preferable range of above-mentioned weight portion crude drug is: 20~25 parts of winter folium moris, 30~35 parts of Cortex Phellodendris, 25~30 parts of Fructus Viticises, 10~15 parts of Rhizoma Cimicifugaes, 20~35 parts of Herba Ecliptaes, 25~40 parts of the Fructus Kochiae.
After above-mentioned each crude drug weighed up, adding 5-10 concentration doubly by above-mentioned preparation method was that 75% medical alcohol soaks, filters, and the as clear as crystal medicinal liquid branch that obtains installs in the bottle, is mulberry cypress hair growth liniment of the present invention.
Mulberry cypress hair growth liniment of the present invention, trial test and mechanism research have been carried out, animal rat has been made the pharmacodynamic observation of hair growth, this liniment can make the chaeta speed of growth accelerate, and gross weight increases, and dermis thickness is increased, the hair follicle number increases, can promote local blood circulation, activate hair follicle cell, the obvious trichogenous effect of tool.In addition this liniment has been carried out the laboratory observation of antibacterial action, the result shows that this liniment killed staphylococcus aureus, escherichia coli and Pseudomonas aeruginosa fully in 24 hours, points out this liniment external various bacteria to be had stronger bactericidal action.In addition three kinds of common pathomycete trichophyton, alpha fungus and Malassezia furfurs are had certain bacteriostasis, MIC is 31.25mg/ml.
Clinical effectiveness and pharmacological action: to 400 many cases hair loss patients, especially 40 routine hair loss patients have been made detailed curative effect tracing observation through, total effective rate is 86%, shows that clinical effectiveness is remarkable.The alopecia of clinical user obviously reduces, and during use, is stained with liniment with absorbent cotton and puts on the skin repeatedly in alopecia place and be coated with, and can see the pore projection after 4 days every day 2~3 times, and later New Development grows gradually, and the fat that can disappear, dandruff removing, antipruritic, more can control recurrence.
Claims (4)
1. mulberry cypress hair growth liniment is characterized in that making this liniment raw materials of effective components medicine and weight portion thereof and is: 10~30 parts of winter folium moris, 10~50 parts of Cortex Phellodendris, 15~40 parts of Fructus Viticises, 5~15 parts of Rhizoma Cimicifugaes, 15~40 parts of Herba Ecliptaes, 10~50 parts of the Fructus Kochiae.
2. mulberry cypress hair growth liniment as claimed in claim 1 is characterized in that making this liniment raw materials of effective components medicine and weight portion thereof and is: 20~25 parts of winter folium moris, 30~35 parts of Cortex Phellodendris, 25~30 parts of Fructus Viticises, 10~15 parts of Rhizoma Cimicifugaes, 20~35 parts of Herba Ecliptaes, 25~40 parts of the Fructus Kochiae.
3. the preparation method of claim 1 or 2 described liniments is characterized in that comprising the following steps:
A) take by weighing each crude drug: winter folium mori, Cortex Phellodendri, Fructus Viticis, Rhizoma Cimicifugae, Herba Ecliptae, the Fructus Kochiae, standby;
B) Fructus Viticis, the Fructus Kochiae of described weight proportion are wrapped with the cloth of sterilizing respectively and be placed in first container, add an an amount of alcohol-pickled week;
C) winter folium mori, Cortex Phellodendri, Rhizoma Cimicifugae, the Herba Ecliptae of described weight proportion are cleaned respectively and be placed in second container, add an an amount of alcohol-pickled week;
D) medicinal liquid in above-mentioned two containers and medicinal residues are merged to soak 10 to 20 days again in the container after, with the whole filterings of medicinal residues, a night is left standstill in medicinal liquid cold preservation, filter with 100 mesh sieves, refilter with the medicinal liquid filter paper at last, the as clear as crystal medicinal liquid that obtains is respectively charged into bottle, is mulberry cypress hair growth liniment.
4. as the preparation method of liniment as described in the claim 3, it is characterized in that it is 75% medical alcohol that described ethanol is selected concentration for use, the ethanol consumption is 5~10 times of drug weight part.
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CN102028822B (en) * | 2010-12-23 | 2012-01-18 | 南京中医药大学 | Mulberry and tuber fleeceflower root hair growing medicinal tea for treating alopecia and poliosis, and preparation method and application thereof |
CN106214898A (en) * | 2016-08-12 | 2016-12-14 | 重庆顶尚生物制品有限责任公司 | Chinese medicine preparation for the treatment of poliosis and preparation method thereof |
CN112826875A (en) * | 2021-03-15 | 2021-05-25 | 福建广生健康科技有限公司 | Traditional Chinese medicine hair growing cream for treating alopecia and preparation method thereof |
CN115554380B (en) * | 2022-06-13 | 2023-09-26 | 浩溪(海南)生物科技有限公司 | Composition for preventing and treating alopecia by acting on hair follicle tissue and application thereof |
Citations (2)
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CN1500506A (en) * | 2002-11-18 | 2004-06-02 | 郭廷悦 | Hair regenerating formulation and its production method |
CN1857562A (en) * | 2006-04-11 | 2006-11-08 | 北京阜康仁生物制药科技有限公司 | Kidney invigorating hair restorer preparation its preparing process |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1500506A (en) * | 2002-11-18 | 2004-06-02 | 郭廷悦 | Hair regenerating formulation and its production method |
CN1857562A (en) * | 2006-04-11 | 2006-11-08 | 北京阜康仁生物制药科技有限公司 | Kidney invigorating hair restorer preparation its preparing process |
Non-Patent Citations (4)
Title |
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佟书娟 等.桑柏生发方的体外抑菌作用研究.《江苏中医药》.2007,第39卷(第10期),第60-62页. |
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