CN103611025A - Liquid medicine for treating acne and preparation method thereof - Google Patents

Liquid medicine for treating acne and preparation method thereof Download PDF

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Publication number
CN103611025A
CN103611025A CN201310600119.8A CN201310600119A CN103611025A CN 103611025 A CN103611025 A CN 103611025A CN 201310600119 A CN201310600119 A CN 201310600119A CN 103611025 A CN103611025 A CN 103611025A
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liquid medicine
leaf
fresh
acne
preparation
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CN201310600119.8A
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CN103611025B (en
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张征西
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Abstract

The invention provides a liquid medicine for treating acne and a preparation method thereof. The preparation method comprises the following steps: immersing fresh grosvenor momordica leaf, fresh peach leaf, dried sweet osmanthus, sophora flavescens and stemona in a mixed solution of alcohol and water for 15 days, and filtering by using a filter cloth of over 200 meshes; directly adding borneol and salicylic acid into the filtered liquid medicine, and uniformly stirring to obtain a finished product. The liquid medicine for treating acne has the advantages of no toxic or side effect, reliable curative effect, convenience in use, low in cost, short in course of treatment, no pain, safety and good use effect.

Description

Liquid medicine of a kind of Acne treatment and preparation method thereof
Technical field
The invention belongs to drug world, be specifically related to liquid medicine of a kind of Acne treatment and preparation method thereof.
Background technology
Acne, is commonly called as comedo, acne, skin sore, is dermatology common disease, frequently-occurring disease.For a kind of, betide pilosebaceous chronic dermatosis, be mainly in Head And Face, the abundant positions of sebaceous gland such as cervical region, shirtfront back.
Clinical topmost medicine adopts Western medicine exactly at present, but Western medicine contains hormone, and side effect is large, is easy to allow people produce dependence, and outbreak repeatedly.
Summary of the invention
For the deficiencies in the prior art, the invention provides liquid medicine of a kind of Acne treatment and preparation method thereof, this liquid medicine does not contain hormone, has no side effect, and not only can well control and Acne treatment, and can also suppress the outbreak repeatedly of acne.
Concrete scheme of the present invention is:
A liquid medicine for Acne treatment, is comprised of the following crude drug of meter by weight ratio:
Fresh Fructus Momordicae leaf 5-15
Fresh leaf of Fructus Persicae 5-15
Dried sweet-scented osmanthus 5-10
Radix Sophorae Flavescentis 5-10
Radix Stemonae 5-10
Water 30-50
Borneolum Syntheticum 0.5-2
Ethanol 60-80
Salicylic acid 2.0-6.0.
Preferred weight part proportioning of above-mentioned formula is:
Fresh Fructus Momordicae leaf 10
Fresh leaf of Fructus Persicae 10
Dried sweet-scented osmanthus 5
Radix Sophorae Flavescentis 5
The Radix Stemonae 5
Water 30
Borneolum Syntheticum 0.5
Ethanol 70
Salicylic acid 4.
The preparation method of the liquid medicine of Acne treatment of the present invention, comprises the following steps:
1) by the weighing of above-mentioned weight portion proportioning, the mixed liquor of fresh Fructus Momordicae leaf, fresh leaf of Fructus Persicae, dried sweet-scented osmanthus, Radix Sophorae Flavescentis and the Radix Stemonae being put into ethanol and water soaks, soak time 15 days;
2) use filter-cloth filterings more than 200 orders;
3) Borneolum Syntheticum, salicylic acid are directly added in the medicinal liquid having filtered and mixed thoroughly, get product.
Described in the present invention's formula, each raw material is all on the books on < < Chinese medicine voluminous dictionary > >, wherein:
Folium Momordicae is the leaf of cucurbitaceous plant Fructus Momordicae, contains the types of materials such as flavone, anthraquinone, tannin, steroidal and terpenoid, volatile oil, saponin, alkaloid, lactone and Coumarins, reducing sugar and polysaccharide, has the antipruritic effect of heat-clearing and toxic substances removing;
Leaf of Fructus Persicae is the leaf of Rosaceae Fructus Persicae Subgenus peach tree, contain glucosides, naringenin, quininic acid, tannin and nitrile glycosides, there is victory damp and clearing heat, the effect of killing parasites for relieving itching, the great-hearted skin quality of youth is had to special efficacy, Main Function is the blood circulation that accelerates skin, to dispelling acne, has certain curative effect;
Flos Osmanthi Fragrantis is the flower of oleaceae plant wooden slippers, has repelling foulness with aromatics, deodorization removing toxic substances delicate fragrance refreshing effect.Fragrance is pure and fresh charming, can drive away dampness in body, to antioxidation, has obvious skin maintenance, skin care effect;
Radix Sophorae Flavescentis is the dry root of leguminous plant Radix Sophorae Flavescentis, has the effect of anti-inflammation, heat clearing and damp drying, and Propiobacterium is had to inhibitory action;
The Radix Stemonae is the dried root of Stemonaceae plant Radix Stemonae Radix stemonae japonicae or radix stemonae tuberosae, containing large number of biological alkali, also sugary, lipid, protein and formic acid, acetic acid, malic acid, citric acid, succinic acid, oxalic acid etc.Have antibacterial, parasite killing, the effects such as delousing, cough for new chronic cough; Pulmonary tuberculosis; Pertussis; Enterobiasis; Body louse; Tinea scabies etc.;
Borneolum Syntheticum is that resin and the volatile oil processed goods of Spore density Borneolum Syntheticum extracts the crystallization obtaining, and has the loose poison of heat clearing away, logical all keys, and loose stagnated fire, improving acuity of vision and removing nebula, antibacterial, the effect of reducing swelling and alleviating pain;
Salicylic acid, for for white crystalline powder, is dispelled the effects such as fetid sweat, relieving itching and eliminating swelling, analgesic antiphlogistic; Grain-positive and gram-negative bacteria and saccharomytes are had to bacteriostasis, can help the penetrance of other drug.
Above-mentioned each raw material, after science is extracted, includes flavone, tannin, and chlorophyll, the effective ingredient such as dextro Borneolum Syntheticum, tannin has astriction, can protect skin, prevents bacterial invasion.Other several compositions are to antibacterial especially micrococcus scarlatinae, and staphylococcus aureus, Propiobacterium have inhibition and killing action in various degree, and certain density ethanol has stronger sterilizing power.Therefore this medicine has the effect of obvious anti-acne bacillus.By clinical observation, the present invention is used for the treatment of acne and truly has good effect.
Beneficial effect of the present invention: this product Acne treatment is nontoxic, have no side effect, curative effect is reliable, easy to use, and expense is low, short treating period, no pain, safety, early application better effects if.
Clinical trial, Acne treatment I level (only having acne), II level (acne and struvite pimple) III level (acne, struvite pimple, pustule), used one to three course for the treatment of, and total effective rate reaches 100%, cure rate 99.8%.Acne treatment IV level (except above-mentioned points, going back nodosity, cyst, polymerism infringement or ulcer) use two to four the course for the treatment of effective percentage 100%, cure rate is not less than 80%.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further details, but is not limitation of the present invention.
Embodiment 1:
A liquid medicine for Acne treatment, comprises the following steps:
(1) fresh Fructus Momordicae leaf 5g, fresh leaf of Fructus Persicae 5g, dried sweet-scented osmanthus 5g, Radix Sophorae Flavescentis 5g and Radix Stemonae 5g being put into concentration is that 75% 60ml ethanol and the mixed liquor of 30ml water soak 15 days;
(2) with silks more than 200 orders, filter;
(3) Borneolum Syntheticum, salicylic acid are directly added in the filtrate of having filtered and mixed thoroughly, get product.
Embodiment 2:
By the method step of embodiment 1, undertaken, different: proportioning raw materials is:
Fresh Fructus Momordicae leaf 15g, fresh leaf of Fructus Persicae 15g, dried sweet-scented osmanthus 10 g, Radix Sophorae Flavescentis 10 g, the Radix Stemonae 10 g, water 50ml, Borneolum Syntheticum 2 g, ethanol 80 ml, salicylic acid 6 g.
Embodiment 3:
By the method step of embodiment 1, undertaken, different: proportioning raw materials is:
Fresh Fructus Momordicae leaf 10g, fresh leaf of Fructus Persicae 10g, dried sweet-scented osmanthus 5g, Radix Sophorae Flavescentis 5g, Radix Stemonae 5g, water 30g, Borneolum Syntheticum 0.5g, ethanol 70g, salicylic acid 4g.
Application example:
Case 1: Zhang, man, 17 years old, Senior Two student, the season in annual autumn in summer, face, this plays acne dorsalis that and falls.Once oral antibiotic, externally-applied ointment, DeGrain, through using above-mentioned liquid medicine, is used by explanation, and after the course for the treatment of, (15 days) acne all disappears.After two courses for the treatment of (30 days), spot disappears.
Case 2: beam so-and-so, female, 20 years old, freshman, facial acne is more.Because of with hands extruding, form tuberosity, through using above-mentioned liquid medicine, by explanation, to use, after three courses for the treatment of, (45 days) acne disappears.The spot staying, maintains medication, after three months, disappears.
Case 3: thank so-and-so, female, 28 years old, nursery teacher, there is acne and struvite pimple in face, medication acne 15 days (course for the treatment of) and struvite pimple disappear.Maintain after medication, within 6 months, have no recurrence.
Case 4: deep certain, female, 34 years old, married, Corporate Finance personnel.Face only has acne, and medication acne 15 days (course for the treatment of) disappear, and maintain after medication, within 3 months, have no recurrence.
Using method of the present invention: adopt outer method of wiping affected part, need not any other medicines (without antibiotic and hormone medicine, do not take medicine, do not have an injection) during treatment, alone this product.Every day is early, middle and late, respectively apply medicinal lotion or ointment 1 time before sleeping, and continuous 15 days was 1 course for the treatment of.Can heal for 1 ~ 3 course for the treatment of.
Maintain medication: after acne is removed, for preventing recurrence, use this product to wipe 1 time for every 10 days, be 6-12 month the course for the treatment of.This product does not contain hormone, safety non-toxic, and anti-acne ability is strong, without any side effects.
Operation instruction of the present invention: 1, this product is external preparation, not oral administration.2, this product spirituosity, is cautious use of ethanol allergy sufferers.3, Pregnant and lactant women can not large area be used.4,, accidentally and after eye contact, please with a large amount of clear water, rinse and solicit doctor's suggestion immediately.5, sealing, lucifuge, puts Liang Chu and preserves.

Claims (3)

1. a liquid medicine for Acne treatment, is characterized in that: by the following raw material of meter by weight ratio, made:
Fresh Fructus Momordicae leaf 5-15
Fresh leaf of Fructus Persicae 5-15
Dried sweet-scented osmanthus 5-10
Radix Sophorae Flavescentis 5-10
Radix Stemonae 5-10
Water 30-50
Borneolum Syntheticum 0.5-2
Ethanol 60-80
Salicylic acid 2.0-6.0.
2. liquid medicine according to claim 1, is characterized in that: by the following raw material of meter by weight ratio, made:
Fresh Fructus Momordicae leaf 10
Fresh leaf of Fructus Persicae 10
Dried sweet-scented osmanthus 5
Radix Sophorae Flavescentis 5
The Radix Stemonae 5
Water 30
Borneolum Syntheticum 0.5
Ethanol 70
Salicylic acid 4.
3. a kind of preparation method of liquid medicine of Acne treatment described in claim 1 or 2, is characterized in that: comprise the following steps:
1) weighing by weight ratio, the mixed liquor of fresh Fructus Momordicae leaf, fresh leaf of Fructus Persicae, dried sweet-scented osmanthus, Radix Sophorae Flavescentis and the Radix Stemonae being put into ethanol and water soaks, soak time 15 days;
2) use filter-cloth filterings more than 200 orders;
3) Borneolum Syntheticum, salicylic acid are directly added in the medicinal liquid having filtered and mixed thoroughly, get product.
CN201310600119.8A 2013-09-30 2013-11-25 Liquid medicine of a kind of Acne treatment and preparation method thereof Expired - Fee Related CN103611025B (en)

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CN201310457185 2013-09-30
CN201310457185.4 2013-09-30
CN2013104571854 2013-09-30
CN201310600119.8A CN103611025B (en) 2013-09-30 2013-11-25 Liquid medicine of a kind of Acne treatment and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109715137A (en) * 2016-07-29 2019-05-03 株式会社爱茉莉太平洋 For inhibiting the composition comprising peach bud extract of sebum secretion
EP3458099A4 (en) * 2016-05-18 2020-07-22 Dermala Inc. Compositions and methods for treating acne vulgaris

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1524553A (en) * 2003-02-27 2004-09-01 王长太 Exterior-applied medicine for treating dermatopathy
CN1927286A (en) * 2005-09-11 2007-03-14 陶园 Chinese medicine composition for treating skin disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1524553A (en) * 2003-02-27 2004-09-01 王长太 Exterior-applied medicine for treating dermatopathy
CN1927286A (en) * 2005-09-11 2007-03-14 陶园 Chinese medicine composition for treating skin disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴震西: "痤疮有哪些外治方法?", 《中医杂志》, vol. 44, no. 10, 31 October 2003 (2003-10-31) *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3458099A4 (en) * 2016-05-18 2020-07-22 Dermala Inc. Compositions and methods for treating acne vulgaris
CN109715137A (en) * 2016-07-29 2019-05-03 株式会社爱茉莉太平洋 For inhibiting the composition comprising peach bud extract of sebum secretion
US11389393B2 (en) 2016-07-29 2022-07-19 Amorepacific Corporation Composition for inhibiting sebum secretion comprising peach sprout extract

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