CN101351203B - 吡咯并喹啉化合物杀灭临床上潜伏微生物的用途 - Google Patents
吡咯并喹啉化合物杀灭临床上潜伏微生物的用途 Download PDFInfo
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- CN101351203B CN101351203B CN2006800500487A CN200680050048A CN101351203B CN 101351203 B CN101351203 B CN 101351203B CN 2006800500487 A CN2006800500487 A CN 2006800500487A CN 200680050048 A CN200680050048 A CN 200680050048A CN 101351203 B CN101351203 B CN 101351203B
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- quinoline
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GBGB0522715.2A GB0522715D0 (en) | 2005-11-08 | 2005-11-08 | New use |
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PCT/GB2006/004178 WO2007054693A1 (en) | 2005-11-08 | 2006-11-08 | Use of pyrroloquinoline compounds to kill clinically latent microorganisms |
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CN101351203B true CN101351203B (zh) | 2013-12-04 |
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JP (1) | JP5542336B2 (ru) |
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CN (1) | CN101351203B (ru) |
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SI (1) | SI1945211T1 (ru) |
WO (1) | WO2007054693A1 (ru) |
ZA (1) | ZA200804454B (ru) |
Families Citing this family (35)
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GB0522715D0 (en) | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
GB0709513D0 (en) * | 2007-05-17 | 2007-06-27 | Helperby Therapeutics Ltd | Topical formulations |
DK2182950T3 (da) * | 2007-05-17 | 2017-11-06 | Helperby Therapeutics Ltd | Anvendelse af 4-(pyrrolidin-1-yl)quinolinforbindelser til at dræbe klinisk latente mikroorganismer |
US9453042B2 (en) | 2007-10-25 | 2016-09-27 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
WO2010048600A1 (en) | 2008-10-24 | 2010-04-29 | Cempra Pharmaceuticals, Inc. | Methods for treating resistant diseases using triazole containing macrolides |
US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
RU2457208C2 (ru) * | 2009-07-06 | 2012-07-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") | 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ |
WO2011121345A1 (en) * | 2010-03-30 | 2011-10-06 | Helperby Therapeutics Limited | Novel combination and use |
GB201013207D0 (en) * | 2010-08-05 | 2010-09-22 | Helperby Therapeutics Ltd | Novel combination |
DK2600869T3 (da) | 2010-08-05 | 2020-11-16 | Helperby Therapeutics Ltd | Kombination af en pyrroloquinolinforbindelse og et beta-lactam-antimikrobielt middel, mupirocin eller chlorhexidin |
GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
US20130245060A1 (en) * | 2010-10-08 | 2013-09-19 | Helperby Therapeutics Limited | Novel composition |
KR101254038B1 (ko) * | 2011-01-12 | 2013-04-12 | 한국화학연구원 | 퀴놀린올 화합물을 유효성분으로 포함하는 항진균 조성물 |
GB201107755D0 (en) | 2011-05-10 | 2011-06-22 | Helperby Therapeutics Ltd | Novel compounds |
RU2658050C2 (ru) | 2012-03-27 | 2018-06-19 | Семпра Фармасьютикалз, Инк. | Парентеральные составы для введения макролидных антибиотиков |
AU2014239959A1 (en) | 2013-03-14 | 2015-10-01 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
US9751908B2 (en) | 2013-03-15 | 2017-09-05 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
SI3027613T1 (sl) * | 2013-07-25 | 2018-10-30 | Uniwersytet Jagiellonski | Derivati pirolokvinolina kot 5-HT6 antagonisti, postopek priprave in uporabe le-teh |
WO2015192031A1 (en) * | 2014-06-12 | 2015-12-17 | Cem-102 Pharmaceuticals, Inc. | Compositions and methods for treating bone and joint infections |
GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
US20180214440A1 (en) | 2015-04-11 | 2018-08-02 | Helperby Therapeutics Limited | Oral composition |
US10653679B2 (en) * | 2015-05-04 | 2020-05-19 | Board Of Trustees Of Michigan State University | Compositions and methods for inhibiting bacterial growth |
GB201518969D0 (en) | 2015-10-27 | 2015-12-09 | Helperby Therapeutics Ltd | Triple combination |
GB201703898D0 (en) | 2017-03-10 | 2017-04-26 | Helperby Therapeautics Ltd | Method |
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CN109503569B (zh) * | 2019-01-03 | 2021-01-15 | 山东大学 | 噻唑类衍生物及其制备方法和应用 |
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