CN101297867B - Cigarette for quitting drug and preparation thereof - Google Patents
Cigarette for quitting drug and preparation thereof Download PDFInfo
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- CN101297867B CN101297867B CN2008101240219A CN200810124021A CN101297867B CN 101297867 B CN101297867 B CN 101297867B CN 2008101240219 A CN2008101240219 A CN 2008101240219A CN 200810124021 A CN200810124021 A CN 200810124021A CN 101297867 B CN101297867 B CN 101297867B
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Abstract
The invention discloses a cigarette for detoxification, wherein, tobacco shreds are composed of tobacco and lotus leaves absorbing ingredients of a detoxification drug, and the tobacco accounts for 10 to 50 percent of the total mass of the tobacco shreds. The invention further discloses a preparation method of the cigarette for detoxification. The cigarette for detoxification of the invention can allow drug aerosol to be absorbed by the human inner mucosa in the ionic state with the help of a smoking mode of the cigarette by the people, thus having significant efficacy, rapid effectiveness and facilitating the fine adjustment and control of the dose of the psychotropic drug; furthermore, the preparation method is simple and easy to realize, thus having broad market prospect.
Description
Technical field
The present invention relates to a kind of new anti-additive medicament formulation, be specifically related to a kind of cigarette for rehabilitation.
Background technology
The addicts is at the therapeutic process of quitting drug abuse, giving up, and it is how to determine suitable anti-additive medicament dosage according to patient's symptom that the doctor generally runs into a basic difficult problem.The using dosage of anti-additive medicament and patient's body situation, the time length that patient's drugs are sucked and the drugs stuff quality discrepancy that the patient bought all have close getting in touch.Determine that according to above-mentioned situation appropriate drug dosage itself is not a nothing the matter just, still more in the middle of actual therapeutic, a lot of patients can exaggerate the sense of discomfort and the somatic reaction of health without thinking, to belittle the curative effect of treatment, painful unlimited artificial amplification, to seek sympathy or to refuse treatment, this more clinical withdrawal and treatment has increased artificial difficulty and uncertain factor.And the whether accurate effect that directly has influence on drug rehabilitation, gives up that dosage uses.Therefore, how under existing anti-additive medicament effect, the dosage of anti-additive medicament is done appropriate regulation to satisfy patient self physiological requirements, just become the problem that present drug rehabilitation field of medicaments presses for solution, still blank in world wide aspect this.
In addition, through long clinical observation, the drug addict more than 90% has the custom of smoking, this is just for the invention provides a good idea, if anti-additive medicament is combined with the cigarette form, neither can cause patient's dislike, can reach the effect of good fine setting drug dose again.
Summary of the invention
Technical problem to be solved by this invention provides a kind of cigarette for rehabilitation, can act synergistically with existing anti-additive medicament, and the dosage of anti-additive medicament is made appropriate regulation, in the hope of reaching the anti-additive medicament dosage of the most suitable patient's self-condition, accelerates to give up process.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is as follows:
A kind of cigarette for rehabilitation is characterized in that pipe tobacco wherein is made up of tobacco and the lotus leaf that absorbed the anti-additive medicament composition, and tobacco accounts for 10～50% of pipe tobacco gross mass, preferred 25～30%.
Wherein, described anti-additive medicament comprises following parts by weight of traditional Chinese medicines and western medicine component:
The a traditional Chinese medicinal components:
8～12 parts of Ligusticum wallichiis, 8～15 parts of rhizoma typhoniis, 10～20 parts of datura flowers, 5～10 parts of arisaema cum bile, 10～15 parts of greater celandines, 10～15 parts of decumbent corydalis tubers, windproof 8～15 parts, 8～15 parts of the barks of eucommia, 8～15 parts of saline cistanches;
The b western medicine component:
10～25 parts of maleic acids, 10～25 parts of sodium hydrogens, 15～30 parts of vitamin B6s.
Above-mentioned compound medicine for dropping drug is by the compound that the combines senior behavior reflex district to human brain by the medicine of different performance, effectiveness, different parts, the different tissues function that heroin pharmacology reflection is constituted, carry out the mutual support of efficient functional, make that curative effect is optimized to come collaboratively to finish that analgesia relieves the pain, tranquilizing and allaying excitement, narcohypnosis, the drug addiction reaction of the intermittent excited tic spasm phenomenon of brain tissue when giving up with the control human body.Take a tonic or nourishing food to build up one's health agent vitamin B6, sodium hydrogen immixture mutually with the Chinese medicine of strong filling liver kidney such as the bark of eucommia, saline cistanche with the spirit in the Western medicine, nervous system and brain tissue injury are repaired fast.
Above-mentioned compound medicine for dropping drug is made effect with the combination of Chinese medicine Western medicine and is mended and to taste: as calming the liver to stop the wind, antiallergy antihistaminicum, tranquilizing to relieve muscle spasm calm the nerves, improvement is slept, repair impaired brain tissue and nerve fiber.Carry on frivolous with the efficacy of a drug of Ligusticum wallichii, rhizoma typhonii, top, through mountain peak acts on brain volume page or leaf and hippocampus, nucleus ceruleus, the memory district of brain fold wrinkle deep layer, many target spots of nociceptive reflex threshold are carried out whole control.With arisaema cum bile, windproof elimination nervous system, neutral net and brain tissue, the inflammation in nerve fibre limit week and tissue edema, improve lesion tissue.The symptom of epileptiform cerebral discharges is effectively pacified, and compound medicine for dropping drug of the present invention mainly is the unsound brain tissue electric discharge phenomena of suppression human body.Be that the dispelling pathogenic wind and eliminating phlegm said of the traditional Chinese medical science is calming the liver to stop the wind.Suppress the symptomatic reaction formula of brain deep tissues with greater celandine, decumbent corydalis tuber, the datura flower analgesia anesthesia that relieves the pain, take a tonic or nourishing food to build up one's health nerve cell with sodium hydrogen, vitamin B6 and can reach quick qi-restoratives damage, with maleic acid antiallergy antihistaminicum spasmolysis, the signal of telecommunication of organizing spasm to produce that improves nervous system neutral net, networking is unusual, transmission is obstructed, and makes it unblocked.Spiritual restraint with datura flower, the deep fold of incision brain tissue " memory district ", the pernicious memory of the toxicity reflecting surface in the senior behavior reflex district of control brain tissue, because of the discharge carelessly of focal lesion tissue exception response reaction equation, when the endogenic morphine donor of human body is not enough, accelerate function of organization's reparation of health with the filling liver kidney of bark of eucommia Herba Cistanches and react after the neurotransmission that acknowledgement mechanism caused of interference heroin is obstructed to alleviate drug addiction.
The reaction of the so-called toxicity of human body is exactly conduction behind the nerve fiber brain tissue impairment parerethisis that brain tissue shows that is obstructed, cause nervous tissue edema's electrical signal transfer to be obstructed after, organize spasm generation tic sample to send out the addiction phenomenon.Along with increasing progressively fast of function modulability hormones such as cortex renis hormone, enkephalins, dopamine, abstinence reaction can be gradually disappearance, make the mind spirit of the human body unordered confusing state that causes that loses one's temper, become the health status of controlled orderly easy nature.Constituted the control net of interfering enkephalins, dopamine, cortex hormone of aadrenaline the brain function nervous system to be played the award acknowledgement mechanism by above medicine, make associated hormone secretion, discharge, reply, metabolism, transmission, spend the manic phase of giving up unconsciously reposefully the patient, thereby can reach the steadily quiet withdrawal effect of nature.
Prepare the method for above-mentioned cigarette for rehabilitation, comprise the steps:
1, lotus leaf is dry after distilling;
2, lotus leaf is immersed in the anti-additive medicament solution, dry behind the absorption concoction, repeatable operation 2～5 times;
3, lotus leaf is carried out chopping behind the smooth grinding shaping;
4, the lotus leaf silk that step 3 is obtained mixes with pipe tobacco, makes cigarette.
Wherein, after step 2, can increase following steps before the step 3: add olive oil, sesame oil or palm oil, lotus leaf is carried out the kneading glazing soften, can realize that drug ingedient and air are isolated, prolong the medicinal effects and the memory time of cigarette.
Wherein, can add liquor that quality is an anti-additive medicament solution quality 0.1～10% in the anti-additive medicament solution described in the step 2 or/and 0.1～10% honey or/and 0.1～10% essence, to regulate mouthfeel.
Wherein, described anti-additive medicament solution prepares as follows: anti-additive medicament is the solubility Western medicine, then Western medicine is dissolved into solution with warm water; Or anti-additive medicament is Chinese medicine, then Chinese medicine boiled, and leaches concoction; Or anti-additive medicament is the compound of Chinese medicine and Western medicine, then earlier Chinese medicine boiled and gets juice, then Western medicine dissolved in Chinese medicine juice.Wherein, available ultrasonic extraction of the extraction of described Chinese medicinal ingredients or super critical extraction are replaced and are boiled extraction method.
The preparation method of the preferred a kind of cigarette for rehabilitation of the present invention comprises the steps:
1, lotus leaf is dry after distilling;
2, with 8～12 parts of traditional Chinese medicinal components Ligusticum wallichiis, 8～15 parts of rhizoma typhoniis, 10～20 parts of datura flowers, 5～10 parts of arisaema cum bile, 10～15 parts of greater celandines, 10～15 parts of decumbent corydalis tubers, windproof 8～15 parts, 8～15 parts of the barks of eucommia and saline cistanche are boiled for 8～15 parts, leach concoction, with 10～25 parts of western medicine component maleic acids, 10～25 parts of sodium hydrogens and vitamin B6 dissolve in the Chinese medicine juice for 15～30 parts, get anti-additive medicament solution, can add liquor that quality is an anti-additive medicament solution quality 0.1～10% or/and 0.1～10% honey or/and 0.1～10% essence, to regulate mouthfeel, lotus leaf is immersed in the anti-additive medicament solution, dry behind the absorption concoction, repeatable operation 2～5 times;
3, add olive oil, sesame oil or palm oil, lotus leaf is carried out the kneading glazing soften;
4, lotus leaf is carried out chopping behind the smooth grinding shaping;
5, the lotus leaf silk that step 4 is obtained mixes with pipe tobacco, makes cigarette.
Beneficial effect: cigarette for rehabilitation of the present invention can make the aerosol of medicine be absorbed by the interior mucous membrane of human body with ionic condition by the suction mode of human body to cigarette, and evident in efficacy, effect is quick, is convenient to the control of dosage.The cigarette for rehabilitation of invention can be judged the control pattern to the practical difficulty of control withdrawal and treatment dosage by doctor's subjective analysis, change into by the patient and grasp regulation and control in the mode oneself of smoking, therefore the blindness that has overcome doctor's subjectivity fully is with random, because when the patient does not need the dosage of medicine to take at health, he will naturally refuse himself, stop into medicine and " suck ", this is to quench one's thirst, just need not drink water certainly yearningly as people's drinking-water just.Doctor and patient has been reached curing the fine setting of drug dose between consciously or unconsciously like this.Therefore can get rid of in the process of giving up personality factors, emotional factor fully, etc. the actual interference of human factor because of the patient.Cigarette for rehabilitation of the present invention, its preparation method is simple, is easy to realize that market prospects are wide.
The specific embodiment:
According to following embodiment, the present invention may be better understood.Yet, those skilled in the art will readily understand that the described concrete material proportion of embodiment, process conditions and result thereof only are used to illustrate the present invention, and should also can not limit the present invention described in detail in claims.
Embodiment 1:
After distillation, dry up lotus leaf standby.
Get traditional Chinese medicinal components: 8 parts of Ligusticum wallichiis, 8 parts of rhizoma typhoniis, 12 parts of datura flowers, 8 parts of arisaema cum bile, 10 parts of greater celandines, 10 parts of decumbent corydalis tubers, windproof 10 parts, 10 parts of the barks of eucommia, saline cistanche is boiled for 10 parts, leach concoction, with 12 parts of western medicine component maleic acids, 12 parts of sodium hydrogens, vitamin B6 dissolves in the Chinese medicine juice for 16 parts, add quality and be the liquor (Daqu of 55 degree) of anti-additive medicament solution quality 5% and 2% honey and 0.1% menthol to regulate mouthfeel, must anti-additive medicament solution.Lotus leaf after drying up immersed rubs repeatedly extruding in this anti-additive medicament solution and increase its absorbability, absorb behind the concoction air-dry again, repeatable operation 3 times.
Add an amount of olive oil, lotus leaf is carried out the kneading glazing soften.
Lotus leaf is carried out chopping behind the smooth grinding shaping.
Get 7kg lotus leaf silk and mix, make cigarette with the 3kg pipe tobacco.
Embodiment 2:
After distillation, dry up lotus leaf standby.
Get traditional Chinese medicinal components: 12 parts of Ligusticum wallichiis, 15 parts of rhizoma typhoniis, datura flower l0 part, 10 parts of arisaema cum bile, 15 parts of greater celandines, 15 parts of decumbent corydalis tubers, windproof 15 parts, 15 parts of the barks of eucommia, saline cistanche is boiled for 15 parts, leach concoction, with 25 parts of western medicine component maleic acids, 25 parts of sodium hydrogens, vitamin B6 dissolves in the Chinese medicine juice for 30 parts, add quality and be the liquor (Daqu of 55 degree) of anti-additive medicament solution quality 0.1% and 10% honey and 1% menthol to regulate mouthfeel, must anti-additive medicament solution.Lotus leaf after drying up immersed rubs repeatedly extruding in this anti-additive medicament solution and increase its absorbability, absorb behind the concoction air-dry again, repeatable operation 3 times.
Add an amount of sesame oil, lotus leaf is carried out the kneading glazing soften.
Lotus leaf is carried out chopping behind the smooth grinding shaping.
Get 5kg lotus leaf silk and mix, make cigarette with the 5kg pipe tobacco.
Embodiment 3:
After distillation, dry up lotus leaf standby.
3 parts of peace monarchs are peaceful
Pill is dissolved in 30 parts of water, adds quality and be the liquor (Daqu of 55 degree) of anti-additive medicament solution quality 10% and 5% honey and 0.2% menthol to regulate mouthfeel, must anti-additive medicament solution.Lotus leaf after drying up immersed rubs repeatedly extruding in this anti-additive medicament solution and increase its absorbability, absorb behind the concoction air-dry again, repeatable operation 3 times.
Add an amount of palm oil, lotus leaf is carried out the kneading glazing soften.
Lotus leaf is carried out chopping behind the smooth grinding shaping.
Get 9kg lotus leaf silk and mix, make cigarette with the 1kg pipe tobacco.
Embodiment 4: the clinical practice of cigarette for rehabilitation of the present invention.
Divide 3 groups with 60 people, carry out the strict control treatment.
The preparation of " clear that addiction ": get traditional Chinese medicinal components: 8 parts of Ligusticum wallichiis, 8 parts of rhizoma typhoniis, 12 parts of datura flowers, 8 parts of arisaema cum bile, 10 parts of greater celandines, 10 parts of decumbent corydalis tubers, windproof 10 parts, 10 parts of the barks of eucommia, 10 parts of saline cistanches extract concentrated extract after the mixing.Add western medicine component again: 12 parts of maleic acids, 12 parts of sodium hydrogens, 16 parts of vitamin B6s stir.Be ground into powder after air-dry, can becomes capsule.
Useful respectively " clear that addiction " treats the treatment group of the complementary administration of the cigarette for rehabilitation that appends embodiment 1 preparation simultaneously again, warp " that addiction clearly " is treated but is not obtained the control group of cigarette for rehabilitation and carries out clinical observation on the therapeutic effect with using the control group of " An Junning " merely, rhythm with the repetitive operation of patient in the regular hour shows result of treatment, the results are shown in Table 1.
The asymptomatic center of the few more expression distance of the repetitive operation of patient in giving up process just near more (promptly effective), the fast more expression of the frequent more rhythm of repetitive operation is just far away more apart from asymptomatic center.
The clinical efficacy comparative test result of table 1 cigarette for rehabilitation of the present invention
Annotate: the treatment group compares p＜00.5, p＜0.01 with clear your addiction; Treatment group and An Junning be p＜00.5 relatively, p＜0.01;
Treatment group patient just can control the drug addiction reaction of the phase of giving up more than 90% through 3～5 days, An Junning then needs the drug addiction of the giving up reaction of an ability control 80% in month.React through the drug addiction of giving up of ability control 90% in 3～8 days as not increasing cigarette for rehabilitation drug rehabilitation needs of patients.
Claims (9)
1. cigarette for rehabilitation is characterized in that pipe tobacco wherein is made up of tobacco and the lotus leaf that absorbed the anti-additive medicament composition, and tobacco accounts for 10～50% of pipe tobacco gross mass;
Described anti-additive medicament is made up of following parts by weight of traditional Chinese medicines and western medicine component:
The a traditional Chinese medicinal components:
8～12 parts of Ligusticum wallichiis, 8～15 parts of rhizoma typhoniis, 10～20 parts of datura flowers, 5～10 parts of arisaema cum bile,
10～15 parts of greater celandines, 10～15 parts of decumbent corydalis tubers, windproof 8～15 parts, 8～15 parts of the barks of eucommia,
8～15 parts of saline cistanches;
The b western medicine component:
10～25 parts of maleic acids, 10～25 parts of sodium hydrogens, 15～30 parts of vitamin B6s.
2. cigarette for rehabilitation according to claim 1 is characterized in that tobacco wherein accounts for 25～30% of pipe tobacco gross mass.
3. a method for preparing the described cigarette for rehabilitation of claim 1 is characterized in that it comprises the steps:
(1) lotus leaf is dry after distilling;
(2) lotus leaf is immersed in the anti-additive medicament solution, dry behind the absorption concoction, repeatable operation 2～5 times;
(3) lotus leaf is carried out chopping behind the smooth grinding shaping;
(4) the lotus leaf silk that step (3) is obtained mixes with pipe tobacco, makes cigarette.
4. the preparation method of cigarette for rehabilitation according to claim 3 is characterized in that step (2) afterwards, and step (3) increases following steps before: interpolation olive oil, sesame oil or palm oil carry out the kneading glazing to lotus leaf and soften.
5. according to the preparation method of claim 3 or 4 described cigarette for rehabilitation, it is characterized in that adding in the anti-additive medicament solution described in the step (2) liquor that quality is an anti-additive medicament solution quality 0.1～10% or/and 0.1～10% honey or/and 0.1～10% essence.
6. the preparation method of cigarette for rehabilitation according to claim 3 is characterized in that described anti-additive medicament solution prepares as follows: Chinese medicine is boiled get juice earlier, then Western medicine is dissolved in Chinese medicine juice.
7. the preparation method of cigarette for rehabilitation according to claim 6, it is characterized in that the available ultrasonic extraction of extraction of described Chinese medicinal ingredients or nitrogen dioxide super critical extraction are replaced boils extraction method.
8. according to the preparation method of claim 3 or 6 described cigarette for rehabilitation, it is characterized in that it comprises the steps:
(1) lotus leaf is dry after distilling;
(2) 8～12 parts of traditional Chinese medicinal components Ligusticum wallichiis, 8～15 parts of rhizoma typhoniis, 10～20 parts of datura flowers, 5～10 parts of arisaema cum bile, 10～15 parts of greater celandines, 10～15 parts of decumbent corydalis tubers, windproof 8～15 parts, 8～15 parts of the barks of eucommia and saline cistanche are boiled for 8～15 parts, leach concoction, 10～25 parts of western medicine component maleic acids, 10～25 parts of sodium hydrogens and vitamin B6 are dissolved in the Chinese medicine juice for 15～30 parts, get anti-additive medicament solution, lotus leaf is immersed in the anti-additive medicament solution, dry behind the absorption concoction, repeatable operation 2～5 times;
(3) add olive oil, sesame oil or palm oil, lotus leaf is carried out the kneading glazing soften;
(4) lotus leaf is carried out chopping behind the smooth grinding shaping;
(5) the lotus leaf silk that step (4) is obtained mixes with pipe tobacco, makes cigarette.
9. the preparation method of cigarette for rehabilitation according to claim 8, it is characterized in that adding in the anti-additive medicament solution described in the step (2) liquor that quality is an anti-additive medicament solution quality 0.1～10% or/and 0.1～10% honey or/and 0.1～10% essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101240219A CN101297867B (en) | 2008-06-10 | 2008-06-10 | Cigarette for quitting drug and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101240219A CN101297867B (en) | 2008-06-10 | 2008-06-10 | Cigarette for quitting drug and preparation thereof |
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| Publication Number | Publication Date |
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| CN101297867A CN101297867A (en) | 2008-11-05 |
| CN101297867B true CN101297867B (en) | 2011-05-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101240219A Expired - Fee Related CN101297867B (en) | 2008-06-10 | 2008-06-10 | Cigarette for quitting drug and preparation thereof |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018271B (en) * | 2010-12-06 | 2012-07-25 | 浙江中烟工业有限责任公司 | Tobacco composition in flue-cured type cigarettes |
| CN102907755B (en) * | 2012-09-03 | 2015-07-15 | 上海聚华科技股份有限公司 | Method for homogenizing and mixing tobacco material and backfill liquid |
| CN103284322B (en) * | 2013-04-02 | 2016-07-06 | 徐志强 | A kind of medicated cigarette and other goods and preparation method thereof that can suppress addict that drugs are craved for heart addiction |
| CN104336774A (en) * | 2013-08-05 | 2015-02-11 | 上海世国建设工程有限公司 | Health tobaccos |
| CN103584275B (en) * | 2013-11-14 | 2015-04-01 | 赵秋芝 | Cut tobacco annexing agent for assisting drug treatment |
| CN108208925A (en) * | 2016-12-09 | 2018-06-29 | 金朝晖 | Anti-additive medicament containing anti-additive medicament sucks device, cigarette filter and cigarette |
| CN108713790A (en) * | 2018-04-13 | 2018-10-30 | 孙永德 | Replace traditional tobacco leaf Chinese herbal medicine cigarette preparation method with lotus leaf |
Citations (1)
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| CN1146900A (en) * | 1995-05-13 | 1997-04-09 | 郭恒盛 | Narcotic capsule and its preparing process |
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2008
- 2008-06-10 CN CN2008101240219A patent/CN101297867B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1146900A (en) * | 1995-05-13 | 1997-04-09 | 郭恒盛 | Narcotic capsule and its preparing process |
Non-Patent Citations (2)
| Title |
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| 丁寿根.戒毒品专利技术研究现状.《中国药物滥用防治杂志》.2000,(6),13-17. * |
| 白晓菊等.浅述中医戒毒常用治疗方法.《中国药物滥用防治杂志》.2001,(5),27-29. * |
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