CN101292044B - 寡核苷酸设计和/或核酸检测的方法和/或装置 - Google Patents

寡核苷酸设计和/或核酸检测的方法和/或装置 Download PDF

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Publication number
CN101292044B
CN101292044B CN2006800369768A CN200680036976A CN101292044B CN 101292044 B CN101292044 B CN 101292044B CN 2006800369768 A CN2006800369768 A CN 2006800369768A CN 200680036976 A CN200680036976 A CN 200680036976A CN 101292044 B CN101292044 B CN 101292044B
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nucleic acid
mrow
target nucleic
oligonucleotide
probes
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CN101292044A (zh
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C·W·C·黄
宋永健
李华星
L·D·米勒
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Agency for Science Technology and Research Singapore
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00Subject matter not provided for in other groups of this subclass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
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  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN2006800369768A 2005-08-12 2006-08-08 寡核苷酸设计和/或核酸检测的方法和/或装置 Expired - Fee Related CN101292044B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/202,023 2005-08-12
US11/202,023 US20070042388A1 (en) 2005-08-12 2005-08-12 Method of probe design and/or of nucleic acids detection
PCT/SG2006/000224 WO2007021250A2 (en) 2005-08-12 2006-08-08 Method and/or apparatus of oligonucleotide design and/or nucleic acid detection

Publications (2)

Publication Number Publication Date
CN101292044A CN101292044A (zh) 2008-10-22
CN101292044B true CN101292044B (zh) 2012-11-07

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CN2006800369768A Expired - Fee Related CN101292044B (zh) 2005-08-12 2006-08-08 寡核苷酸设计和/或核酸检测的方法和/或装置

Country Status (7)

Country Link
US (3) US20070042388A1 (enExample)
EP (1) EP1922418A4 (enExample)
JP (1) JP2009504153A (enExample)
KR (1) KR20080052585A (enExample)
CN (1) CN101292044B (enExample)
AU (1) AU2006280489B2 (enExample)
WO (1) WO2007021250A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101138864B1 (ko) * 2005-03-08 2012-05-14 삼성전자주식회사 프라이머 및 프로브 세트를 설계하는 방법, 그에 의하여 설계된 프라이머 및 프로브 세트, 상기 세트를 포함하는 키트, 상기 방법을 컴퓨터가 수행할 수 있도록 하는 프로그램을기록한 컴퓨터 판독가능한 매체 및 상기 세트를 이용한 표적 서열의 동정 방법
US20070042388A1 (en) * 2005-08-12 2007-02-22 Wong Christopher W Method of probe design and/or of nucleic acids detection
US20100159533A1 (en) * 2008-11-24 2010-06-24 Helicos Biosciences Corporation Simplified sample preparation for rna analysis
WO2011046614A2 (en) * 2009-10-16 2011-04-21 The Regents Of The University Of California Methods and systems for phylogenetic analysis
US20110152109A1 (en) * 2009-12-21 2011-06-23 Gardner Shea N Biological sample target classification, detection and selection methods, and related arrays and oligonucleotide probes
US20140163896A1 (en) * 2011-06-16 2014-06-12 University Of Rochester Hiv incidence assays with high sensitivity and specificity
ES2711156T3 (es) * 2012-05-08 2019-04-30 Adaptive Biotechnologies Corp Método para medir y calibrar el sesgo de amplificación en reacciones de PCR multiplexadas
CN105780129B (zh) * 2014-12-15 2019-06-11 天津华大基因科技有限公司 目标区域测序文库构建方法
US11319602B2 (en) 2017-02-07 2022-05-03 Tcm Biotech Internationl Corp. Probe combination for detection of cancer
US10787699B2 (en) * 2017-02-08 2020-09-29 Microsoft Technology Licensing, Llc Generating pluralities of primer and payload designs for retrieval of stored nucleotides
JP6995604B2 (ja) * 2017-12-15 2022-01-14 東洋鋼鈑株式会社 一塩基多型検出用プローブの設計方法及びプローブセット
CN109097450B (zh) * 2018-08-30 2022-05-13 江苏省疾病预防控制中心 一种核酸序列非依赖的全rna扩增方法
KR102020614B1 (ko) * 2018-09-11 2019-09-11 한국과학기술정보연구원 결핵 진단용 프라이머 세트 및 이의 용도
WO2020054906A1 (ko) * 2018-09-11 2020-03-19 한국과학기술정보연구원 목표 유전자를 검출하기 위한 프라이머의 설계 방법
CN115101128B (zh) * 2022-06-29 2023-09-15 纳昂达(南京)生物科技有限公司 一种杂交捕获探针脱靶危险性评估的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236633A1 (en) * 2000-11-21 2003-12-25 Affymetrix, Inc. Methods for oligonucleotide probe design
US20040259124A1 (en) * 2003-02-19 2004-12-23 Affymetrix, Inc. Methods for oligonucleotide probe design

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000194554A (ja) * 1998-12-25 2000-07-14 Nec Corp 演算処理装置
GB2377017A (en) * 2001-06-28 2002-12-31 Animal Health Inst Detection of foot and mouth disease virus
CN100392097C (zh) * 2002-08-12 2008-06-04 株式会社日立高新技术 使用dna微阵列的核酸检测方法以及核酸检测装置
US20070042388A1 (en) * 2005-08-12 2007-02-22 Wong Christopher W Method of probe design and/or of nucleic acids detection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236633A1 (en) * 2000-11-21 2003-12-25 Affymetrix, Inc. Methods for oligonucleotide probe design
US20040259124A1 (en) * 2003-02-19 2004-12-23 Affymetrix, Inc. Methods for oligonucleotide probe design

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SUNG,W-K. et al..Fast and accurate probe selection algorithm for large genomes.《Proceedings IEEE Computer Society Bioinformatics Conference》.2003,第2卷65-74. *

Also Published As

Publication number Publication date
US20090053708A1 (en) 2009-02-26
CN101292044A (zh) 2008-10-22
AU2006280489B2 (en) 2012-05-24
AU2006280489A1 (en) 2007-02-22
KR20080052585A (ko) 2008-06-11
JP2009504153A (ja) 2009-02-05
US8234079B2 (en) 2012-07-31
WO2007021250A3 (en) 2007-07-05
WO2007021250A2 (en) 2007-02-22
EP1922418A2 (en) 2008-05-21
US20070042388A1 (en) 2007-02-22
US20120309643A1 (en) 2012-12-06
EP1922418A4 (en) 2010-02-03

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