CN101263908A - Blood fat reducing soft capsule health care food and its preparation - Google Patents

Blood fat reducing soft capsule health care food and its preparation Download PDF

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Publication number
CN101263908A
CN101263908A CN200810105088.8A CN200810105088A CN101263908A CN 101263908 A CN101263908 A CN 101263908A CN 200810105088 A CN200810105088 A CN 200810105088A CN 101263908 A CN101263908 A CN 101263908A
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China
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extract
preparation
soft capsule
weight portions
blood fat
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CN200810105088.8A
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CN101263908B (en
Inventor
姚自奇
李东
温凯
冯霖
梁绍隆
庄艳玲
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Beijing Nutrient Source Research Institute
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BEIJING KEWEIHUA FOOD ENGINEERING AND TECHNOLOGY Co Ltd
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Abstract

The invention discloses a soft-capsule healthcare food for reducing blood lipid and a preparation method, belonging to the technical field of healthcare food, which is characterized in that the preparation method comprises the steps as follows: panax notoginseng extract and ginkgo biloba extract are added in vegetable oil for dissolution; then DHA, EPA, soybean lecithin, beeswax and ethyl cellulose are added and completely evenly mixed with a spiral mixer; and passing a colloid mill, degassing, pressing pills, drying in setting, drying in disk arraying, selecting pills and polishing are conducted to obtain the product; and the formula comprises the following components by weight: 10 to 100 panax notoginseng extract, 10 to 100 ginkgo biloba extract, 1 to 50 DHA, 1 to 50 EPA, 10 to 80 beeswax, 10 to 50 soybean lecithin, 5 to 50 ethyl cellulose and 500 to 1000 vegetable oil. The soft-capsule healthcare food for reducing blood lipid and the preparation method have the advantages that technology is advanced; the product has the healthcare functions such as reducing blood lipid; the effective components of panax notoginseng and ginkgo biloba can be extracted more effectively with the adopted extraction method; dosage is greatly reduced; and therapeutic effect is improved.

Description

A kind of blood fat reducing soft capsule health food and preparation method thereof
Technical field
The invention belongs to the health food technology field, relate to a kind of blood fat reducing soft capsule health food with Notogineng Extract, ginkgo biloba p.e, DHA and EPA primary raw material and preparation method thereof particularly.
Background technology
Along with improving constantly of social progress and people society level, people's diet structure and life style change gradually.Cardiovascular and cerebrovascular disease especially high fat of blood, the blood viscousness incidence of disease rises year by year, and this has become a very serious social concern.Put prevention first, the health food with hypolipemic function more and more is subjected to people's welcome.
The present invention overcomes prior art and supplies, and with Notogineng Extract, ginkgo biloba p.e, DHA and EPA primary raw material, has researched and developed a kind of blood fat reducing soft capsule health food and preparation method thereof.
Summary of the invention
The object of the invention provides a kind of blood fat reducing soft capsule health food and preparation method thereof.
Blood fat reducing soft capsule of the present invention is made with Notogineng Extract, ginkgo biloba p.e, DHA and EPA primary raw material.
The preparation method of blood fat reducing soft capsule of the present invention is, Notogineng Extract, ginkgo biloba p.e added in 60~80 ℃ the vegetable oil and dissolve, add DHA (22 charcoal acid), EPA (20 charcoal pentaene acid), soybean lecithin, beeswax, ethyl cellulose again, fully mix with helical mixer, cross colloid mill, the degassing, pelleting, typing is dry, row is coiled drying, select ball, polishing makes blood fat reducing soft capsule health food of the present invention;
Described Notogineng Extract preparation process is pseudo-ginseng to be selected remove impurity, after the cleaning, adds 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~75 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, 6~12KGY 60The Co irradiation sterilization is preserved standby;
Described ginkgo biloba p.e preparation process is ginkgo leaf to be selected remove impurity, and after the cleaning, the water that adds 5~20 times extracts 1~3 time, each 20~100min extracts 45 ℃~95 ℃ of temperature, merges extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, extract a, filter residue added 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~75 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, get extract b, extract a and extract b are mixed 6~12KGY 60The Co irradiation sterilization is preserved standby;
Described vegetable oil is any one in soybean oil, olive oil, peanut oil, siritch, walnut oil, the bay-oil;
Blood fat reducing soft capsule formula for a product of the present invention is, Notogineng Extract 10~100 weight portions, ginkgo biloba p.e 10~100 weight portions, DHA 1~50 weight portion, EPA 1~50 weight portion, beeswax 10~80 weight portions, soybean lecithin 10~50 weight portions, ethyl cellulose 5~50 weight portions, vegetable oil 500~1000 weight portions;
The main functional component of blood fat reducing soft capsule of the present invention is total saponin, flavones, DHA, EPA.
The present invention is a primary raw material with Notogineng Extract, ginkgo biloba p.e, DHA and EPA, makes by advanced technology technology, and prescription is reasonable, exact efficacy, and effect stability, main functional component is total saponin, flavones, DHA, EPA.Experimental study finds that product of the present invention has the health care of reducing blood lipid, also has effects such as hypotensive, anti-oxidant, antifatigue.The extracting method that the present invention adopts can more effectively be extracted pseudo-ginseng, effective component of ginkgo leaf, goes the rough essence of depositing, and greatly reduces dose, and has improved curative effect, because conventional extracting method.
The specific embodiment
The following examples help those skilled in the art more fully to understand the present invention, but do not limit the present invention in any way.
Embodiment 1
Pseudo-ginseng selected remove impurity, after the cleaning, add 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~95 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, 6~12KGY 60The Co irradiation sterilization is preserved standby;
Ginkgo leaf selected remove impurity, after the cleaning, the water that adds 5~20 times extracts 1~3 time, each 20~100min extracts 45 ℃~75 ℃ of temperature, merges extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, extract a, filter residue added 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~75 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, get extract b, extract a and extract b are mixed 6~12KGY 60The Co irradiation sterilization is preserved standby;
Notogineng Extract, ginkgo biloba p.e added in 60~80 ℃ the vegetable oil and dissolve, add DHA (22 charcoal acid), EPA (20 charcoal pentaene acid), soybean lecithin, beeswax, ethyl cellulose again, fully mix with helical mixer, cross colloid mill, the degassing, pelleting, typing is dry, and row is coiled drying, selects ball, polishing makes blood fat reducing soft capsule health food of the present invention;
Vegetable oil is any one in soybean oil, olive oil, peanut oil, siritch, walnut oil, the bay-oil;
Formula for a product is Notogineng Extract 10~100 weight portions, ginkgo biloba p.e 10~100 weight portions, DHA 1~50 weight portion, EPA 1~50 weight portion, beeswax 10~80 weight portions, soybean lecithin 10~50 weight portions, ethyl cellulose 5~50 weight portions, vegetable oil 500~1000 weight portions.
Embodiment 2
Pseudo-ginseng selected remove impurity, after the cleaning, add 5 times the ultrasonic extraction of 85% ethanol 3 times, each 60min extracts 45 ℃ of temperature, ultrasonic power 100W, supersonic frequency 40kHz merges extracting liquid filtering, concentrates, cross silica gel column chromatography, eluent concentrates, spray-drying, 10KGY 60The Co irradiation sterilization is preserved standby;
Ginkgo leaf selected remove impurity, after the cleaning, the water that adds 5 times extracts 3 times, each 60min extracts 55 ℃ of temperature, merges extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, extract a, filter residue added 10 times the ultrasonic extraction of 80% ethanol 2 times, each 50min, extract 55 ℃ of temperature, ultrasonic power 150W, supersonic frequency 60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, get extract b, extract a and extract b are mixed 10KGY 60The Co irradiation sterilization is preserved standby;
Notogineng Extract, ginkgo biloba p.e added dissolving in 70 ℃ the vegetable oil (any one in soybean oil, olive oil, peanut oil, siritch, walnut oil, the bay-oil), add DHA, EPA, soybean lecithin, beeswax, ethyl cellulose again, fully mix with helical mixer, cross colloid mill, the degassing, pelleting, typing is dry, and row is coiled drying, selects ball, polishing makes blood fat reducing soft capsule health food of the present invention.
Blood fat reducing soft capsule formula for a product of the present invention is Notogineng Extract 80 weight portions, ginkgo biloba p.e 60 weight portions, the DHA25 weight portion, EPA 15 weight portions, beeswax 40 weight portions, soybean lecithin 30 weight portions, ethyl cellulose 15 weight portions, vegetable oil 700 weight portions; Make the soft capsule of 0.5g/ grain.
Embodiment 3
Pseudo-ginseng selected remove impurity, after the cleaning, add 15 times the ultrasonic extraction of 65% ethanol 2 times, each 40min extracts 55 ℃ of temperature, ultrasonic power 120W, supersonic frequency 50kHz merges extracting liquid filtering, concentrates, cross silica gel column chromatography, eluent concentrates, spray-drying, 8KGY 60The Co irradiation sterilization is preserved standby;
Ginkgo leaf selected remove impurity, after the cleaning, the water that adds 15 times extracts 2 times, each 50min extracts 85 ℃ of temperature, merges extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, extract a, filter residue added 20 times the ultrasonic extraction of 65% ethanol 1 time, each 80min, extract 65 ℃ of temperature, ultrasonic power 80W, supersonic frequency 20kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, get extract b, extract a and extract b are mixed 8KGY 60The Co irradiation sterilization is preserved standby;
Notogineng Extract, ginkgo biloba p.e added dissolving in 65 ℃ the vegetable oil (any one in soybean oil, olive oil, peanut oil, siritch, walnut oil, the bay-oil), add DHA, EPA, soybean lecithin, beeswax, ethyl cellulose again, fully mix with helical mixer, cross colloid mill, the degassing, pelleting, typing is dry, and row is coiled drying, selects ball, polishing makes blood fat reducing soft capsule health food of the present invention.
Blood fat reducing soft capsule formula for a product of the present invention is Notogineng Extract 50 weight portions, ginkgo biloba p.e 30 weight portions, the DHA20 weight portion, EPA 10 weight portions, beeswax 25 weight portions, soybean lecithin 15 weight portions, ethyl cellulose 10 weight portions, vegetable oil 500 weight portions; Make the soft capsule of 0.3g/ grain.

Claims (6)

1. blood fat reducing soft capsule health food and preparation method thereof with Notogineng Extract, ginkgo biloba p.e, DHA and EPA primary raw material, is characterized in that, with dissolving in Notogineng Extract, the ginkgo biloba p.e adding vegetable oil, add DHA, EPA, soybean lecithin, beeswax, ethyl cellulose again, fully mix with helical mixer, cross colloid mill, the degassing, pelleting, typing is dry, row is coiled drying, select ball, polishing makes blood fat reducing soft capsule health food of the present invention.
2. a kind of blood fat reducing soft capsule health food according to claim 1 and preparation method thereof is characterized in that, described Notogineng Extract preparation process is pseudo-ginseng to be selected remove impurity, after the cleaning, add 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~75 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, 6~12KGY 60The Co irradiation sterilization is preserved standby.
3. a kind of blood fat reducing soft capsule health food according to claim 1 and preparation method thereof is characterized in that, described ginkgo biloba p.e preparation process is ginkgo leaf to be selected remove impurity, after the cleaning, the water that adds 5~20 times extracts each 20~100min 1~3 time, extract 45 ℃~95 ℃ of temperature, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, extract a, filter residue added 5~20 times the ultrasonic extraction of 60%~90% ethanol 1~3 time, each 20~100min, extract 45 ℃~75 ℃ of temperature, ultrasonic power 80~150W, supersonic frequency 15~60kHz, merge extracting liquid filtering, concentrate, cross silica gel column chromatography, eluent concentrates, spray-drying, get extract b, extract a and extract b are mixed 6~12KGY 60The Co irradiation sterilization is preserved standby.
4. a kind of blood fat reducing soft capsule health food according to claim 1 and preparation method thereof is characterized in that, described vegetable oil is any one in soybean oil, olive oil, peanut oil, siritch, walnut oil, the bay-oil.
5. according to claim 1 or 4 described a kind of blood fat reducing soft capsule health foods and preparation method thereof, it is characterized in that described vegetable oil is heated to 60~80 ℃.
6. according to claim 1 or 4 described a kind of blood fat reducing soft capsule health foods and preparation method thereof, it is characterized in that, described blood fat reducing soft capsule formula for a product is, Notogineng Extract 10~100 weight portions, ginkgo biloba p.e 10~100 weight portions, DHA1~50 weight portions, EPA1~50 weight portions, beeswax 10~80 weight portions, soybean lecithin 10~50 weight portions, ethyl cellulose 5~50 weight portions, vegetable oil 500~1000 weight portions.
CN200810105088.8A 2008-04-25 2008-04-25 Blood fat reducing soft capsule health care food and its preparation Expired - Fee Related CN101263908B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102813683A (en) * 2011-06-09 2012-12-12 北京华夏众芳生物科技有限公司 Gingko leaf extract capable of delaying senescence and preparation method and application thereof
CN103704713A (en) * 2014-01-06 2014-04-09 大连海晏堂生物有限公司 Sea cucumber health-care food with blood fat reducing function and preparation method thereof
CN103989178A (en) * 2014-05-07 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing ginkgo leaf oil
CN103989176A (en) * 2014-05-06 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing radix puerariae extract
CN103989179A (en) * 2014-05-07 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing ginkgo leaf extract
JP5917499B2 (en) * 2011-05-02 2016-05-18 ライオン株式会社 Panaxadiol-containing composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1250244C (en) * 2003-08-09 2006-04-12 朱书和 Composition for preventing and treating hyperlipidemia
CN1331503C (en) * 2004-09-03 2007-08-15 蔡绪旺 Health-care preparation for reducing blood-fat and raising human-body immunity
CN1296061C (en) * 2004-12-29 2007-01-24 庞会心 Health care food for preventing and treating heart brain blood vessel disease and its preparation method

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5917499B2 (en) * 2011-05-02 2016-05-18 ライオン株式会社 Panaxadiol-containing composition
US9510613B2 (en) 2011-05-02 2016-12-06 Lion Corporation Panaxadiol-containing composition
CN102813683A (en) * 2011-06-09 2012-12-12 北京华夏众芳生物科技有限公司 Gingko leaf extract capable of delaying senescence and preparation method and application thereof
CN102813683B (en) * 2011-06-09 2013-12-04 北京华夏众芳生物科技有限公司 Gingko leaf extract capable of delaying senescence and preparation method and application thereof
CN103704713A (en) * 2014-01-06 2014-04-09 大连海晏堂生物有限公司 Sea cucumber health-care food with blood fat reducing function and preparation method thereof
CN103989176A (en) * 2014-05-06 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing radix puerariae extract
CN103989176B (en) * 2014-05-06 2016-02-24 宁波市成大机械研究所 Deep-sea fish oil soft capsules containing kudzu root extract
CN103989178A (en) * 2014-05-07 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing ginkgo leaf oil
CN103989179A (en) * 2014-05-07 2014-08-20 宁波市成大机械研究所 Deep sea fish oil soft capsule containing ginkgo leaf extract

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