CN101243130B - 显示具有改善的流动性的组合物 - Google Patents

显示具有改善的流动性的组合物 Download PDF

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Publication number
CN101243130B
CN101243130B CN2006800303578A CN200680030357A CN101243130B CN 101243130 B CN101243130 B CN 101243130B CN 2006800303578 A CN2006800303578 A CN 2006800303578A CN 200680030357 A CN200680030357 A CN 200680030357A CN 101243130 B CN101243130 B CN 101243130B
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CN
China
Prior art keywords
powder
composition
surface modification
nano particle
solid material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2006800303578A
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English (en)
Chinese (zh)
Other versions
CN101243130A (zh
Inventor
小吉米·R·巴兰
史蒂芬·W·斯泰因
詹姆士·S·斯泰费利
马德琳·P·振八
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3M Innovative Properties Co
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3M Innovative Properties Co
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Publication of CN101243130A publication Critical patent/CN101243130A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2006800303578A 2005-08-05 2006-08-04 显示具有改善的流动性的组合物 Expired - Fee Related CN101243130B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70582105P 2005-08-05 2005-08-05
US60/705,821 2005-08-05
PCT/US2006/030278 WO2007019229A1 (en) 2005-08-05 2006-08-04 Compositions exhibiting improved flowability

Publications (2)

Publication Number Publication Date
CN101243130A CN101243130A (zh) 2008-08-13
CN101243130B true CN101243130B (zh) 2011-12-07

Family

ID=37311861

Family Applications (1)

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CN2006800303578A Expired - Fee Related CN101243130B (zh) 2005-08-05 2006-08-04 显示具有改善的流动性的组合物

Country Status (7)

Country Link
US (1) US8062670B2 (https=)
EP (1) EP1917301B1 (https=)
JP (2) JP5694643B2 (https=)
CN (1) CN101243130B (https=)
AU (1) AU2006278571B2 (https=)
CA (1) CA2617909C (https=)
WO (1) WO2007019229A1 (https=)

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Also Published As

Publication number Publication date
CN101243130A (zh) 2008-08-13
CA2617909C (en) 2014-02-04
EP1917301B1 (en) 2014-04-23
JP5694643B2 (ja) 2015-04-01
AU2006278571B2 (en) 2011-11-24
CA2617909A1 (en) 2007-02-15
JP2013100352A (ja) 2013-05-23
JP2009503104A (ja) 2009-01-29
WO2007019229A1 (en) 2007-02-15
US20080286362A1 (en) 2008-11-20
EP1917301A1 (en) 2008-05-07
AU2006278571A1 (en) 2007-02-15
US8062670B2 (en) 2011-11-22

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