CN101208070B - 离子络合物 - Google Patents

离子络合物 Download PDF

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Publication number
CN101208070B
CN101208070B CN2006800227822A CN200680022782A CN101208070B CN 101208070 B CN101208070 B CN 101208070B CN 2006800227822 A CN2006800227822 A CN 2006800227822A CN 200680022782 A CN200680022782 A CN 200680022782A CN 101208070 B CN101208070 B CN 101208070B
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CN
China
Prior art keywords
complex
calcium
acp
phosphoprotein
calcium phosphate
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CN2006800227822A
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English (en)
Chinese (zh)
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CN101208070A (zh
Inventor
埃里克·查尔斯·雷诺兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
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University of Melbourne
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Publication of CN101208070A publication Critical patent/CN101208070A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dental Preparations (AREA)
CN2006800227822A 2005-06-24 2006-06-23 离子络合物 Active CN101208070B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69401905P 2005-06-24 2005-06-24
US60/694,019 2005-06-24
PCT/AU2006/000885 WO2006135982A1 (en) 2005-06-24 2006-06-23 Ionic complexes

Publications (2)

Publication Number Publication Date
CN101208070A CN101208070A (zh) 2008-06-25
CN101208070B true CN101208070B (zh) 2011-08-31

Family

ID=37570039

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800227822A Active CN101208070B (zh) 2005-06-24 2006-06-23 离子络合物

Country Status (14)

Country Link
US (2) US8603988B2 (https=)
EP (1) EP1901702B1 (https=)
JP (2) JP2008543887A (https=)
CN (1) CN101208070B (https=)
AR (1) AR057402A1 (https=)
AU (1) AU2006261597B2 (https=)
BR (1) BRPI0611976B1 (https=)
CA (1) CA2612172C (https=)
ES (1) ES2530396T3 (https=)
MX (1) MX2007016312A (https=)
NZ (1) NZ564129A (https=)
PL (1) PL1901702T3 (https=)
RU (1) RU2413497C2 (https=)
WO (1) WO2006135982A1 (https=)

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EP3192489A1 (en) 2004-11-25 2017-07-19 The University of Melbourne Stabilized calcium phosphate complexes
RU2413497C2 (ru) * 2005-06-24 2011-03-10 Дзе Юниверсити Оф Мельбурн Ионные комплексы
ES2698824T3 (es) 2006-02-09 2019-02-06 Univ Melbourne Composición dentífrica con fluoruro
US20070237729A1 (en) * 2006-04-05 2007-10-11 Cadbury Adams Usa, Llc. Impact of calcium phosphate complex on dental caries
CA2645763C (en) 2006-04-05 2013-09-10 Cadbury Adams Usa Llc Calcium phosphate complex in acid containing confectionery
CA2648460C (en) * 2006-04-05 2014-09-23 Cadbury Adams Usa Llc Calcium phosphate complex and salts in oral delivery systems
WO2008153725A2 (en) 2007-05-25 2008-12-18 North Carolina State University Viral nanoparticle cell-targeted delivery platform
DE102008014225A1 (de) * 2008-03-16 2009-09-17 MEDERER Süßwarenvertriebs GmbH Remineralisierende Zahnpflegemittel und Verfahren zu deren Herstellung
DE102008014227A1 (de) * 2008-03-16 2009-10-01 Nova Dentalia Zahnpflege Gmbh Remineralisierende Speichelersatzmittel und Verfahren zu deren Herstellung
JP2010047494A (ja) * 2008-08-20 2010-03-04 Gc Corp 歯牙塗布用組成物
US8951505B2 (en) 2008-10-08 2015-02-10 Georgia Health Sciences University Rsearch Institute, Inc. Methods and systems for mineralization of demineralized tissue
GB0908433D0 (en) * 2009-05-15 2009-06-24 Glaxo Group Ltd Movel composition
WO2011125910A1 (ja) * 2010-03-31 2011-10-13 東洋水産株式会社 カルシウム剤およびその製造方法
BR112013004294A2 (pt) 2010-08-24 2016-05-31 Safewhite Llc métodos e materiais para fornecimento de dentes com uma aparência branca.
US9107838B2 (en) 2012-04-25 2015-08-18 Therametrics Technologies, Inc. Fluoride varnish
JP6908998B2 (ja) * 2013-07-05 2021-07-28 ステラー・バイオウム・インコーポレーテッド 口腔組成物
CN105530909A (zh) 2013-07-23 2016-04-27 墨尔本大学 用于牙齿矿化的组合物及方法
ES2959412T3 (es) 2013-12-24 2024-02-26 Univ Melbourne Composiciones estañosas estabilizadas
JP2016102069A (ja) * 2014-11-27 2016-06-02 株式会社ジーシー 歯面清掃方法、歯面清掃用組成物、及びその使用方法
JP2018502099A (ja) * 2014-12-24 2018-01-25 ザ ユニヴァーシティー オブ メルボルン 石灰化フルオリド組成物
ES2971113T3 (es) 2016-05-26 2024-06-03 Solventum Intellectual Properties Company Pastas dentales terapéuticas y su aplicación
CN107811872B (zh) * 2016-09-13 2020-09-15 北京大学 一种快速牙釉质矿化的方法
EP3538053B1 (en) 2016-11-08 2026-04-15 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
KR101772449B1 (ko) * 2016-12-27 2017-08-30 주식회사 하이센스바이오 신규한 펩타이드
JP7142943B2 (ja) 2017-03-14 2022-09-28 ザ ユニバーシティー オブ メルボルン 歯肉炎の処置
JP7138352B2 (ja) 2017-03-14 2022-09-16 ザ ユニバーシティー オブ メルボルン 過敏症を治療するための複合体
CN108524290A (zh) * 2018-06-28 2018-09-14 吉林省登泰克牙科材料有限公司 牙科预防龋齿组合物及其制备方法
US12569417B2 (en) 2019-03-13 2026-03-10 The University Of Melbourne Compositions and methods for promoting mineralization
KR102674595B1 (ko) * 2019-05-27 2024-06-11 가부시키가이샤 지씨 치과용 키트 및 우식 예방 방법
WO2021001529A1 (de) 2019-07-04 2021-01-07 Ferton Holding S.A. Zusammensetzung zur remineralisierung von zähnen
WO2021059215A2 (en) * 2019-09-25 2021-04-01 Church & Dwight Co., Inc. Oral care composition
CN111715408B (zh) * 2020-06-30 2021-07-02 中南大学 一种用于浮选白钨矿中萤石的浮选药剂及其浮选方法
GB202010987D0 (en) 2020-07-16 2020-09-02 Dentherapy Ltd Oral care compositions and methods
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
WO2025008636A1 (en) 2023-07-06 2025-01-09 Dentherapy Ltd Oral care compositions for use in the treatment of dental health conditions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015628A (en) * 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride

Family Cites Families (18)

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US4522805A (en) 1983-06-08 1985-06-11 Norman Gordon Tooth and gum dentifrice
CA1315480C (en) * 1986-06-12 1993-03-30 Eric Charles Reynolds Phosphopeptides
US6056930A (en) 1989-05-24 2000-05-02 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US5227154A (en) 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
EP0651652B1 (en) 1992-06-29 2000-02-09 The University Of Melbourne Treatment for sensitive teeth
JP2975337B2 (ja) * 1997-02-20 1999-11-10 雪印乳業株式会社 カルシウム複合体
JP3742523B2 (ja) * 1998-02-27 2006-02-08 雪印乳業株式会社 高分子型カルシウム・ホスホペプチド複合体
FR2791573B1 (fr) 1999-03-30 2003-04-11 Pf Medicament Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate
US6521215B2 (en) 1999-05-28 2003-02-18 Devin Okay Compositions and methods for tooth treatment
US6685920B2 (en) 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
GB9929919D0 (en) 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
AUPR517701A0 (en) * 2001-05-21 2001-06-14 University Of Melbourne, The Dental restorative materials
CA2469498C (en) 2002-01-03 2009-06-02 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
NZ522071A (en) 2002-10-18 2005-07-29 Patrick Joseph Silcock Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
JP4340069B2 (ja) 2003-01-10 2009-10-07 雪印乳業株式会社 カルシウム複合体の製造法
US20050089481A1 (en) * 2003-10-23 2005-04-28 Gc Corporation Composition for caries prevention
BRPI0610885B1 (pt) 2005-06-07 2018-07-10 The University Of Melbourne Mineralização dental
RU2413497C2 (ru) * 2005-06-24 2011-03-10 Дзе Юниверсити Оф Мельбурн Ионные комплексы

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015628A (en) * 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
WO1998040406A1 (en) * 1997-03-13 1998-09-17 The University Of Melbourne Calcium phosphopeptide complexes
WO2003059304A1 (en) * 2002-01-03 2003-07-24 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and flouride

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
赵琼芝.酪蛋白磷酸多肽钙氟磷复合体对牙釉质缺损再矿化的试验研究.中华口腔医学杂志.2001,36(6),421－423. *
赵琼芝.酪蛋白磷酸肽钙氟磷复合体溶液对牙釉质缺损的再矿化作用.安全预防医学.2001,8(1),6-8. *

Also Published As

Publication number Publication date
PL1901702T3 (pl) 2015-07-31
US8603988B2 (en) 2013-12-10
CA2612172C (en) 2013-05-14
WO2006135982A1 (en) 2006-12-28
BRPI0611976A2 (pt) 2010-10-13
JP2013028644A (ja) 2013-02-07
EP1901702A4 (en) 2012-01-18
RU2413497C2 (ru) 2011-03-10
US20100215593A1 (en) 2010-08-26
MX2007016312A (es) 2008-03-05
CN101208070A (zh) 2008-06-25
ES2530396T3 (es) 2015-03-02
EP1901702A1 (en) 2008-03-26
EP1901702B1 (en) 2014-11-26
JP2008543887A (ja) 2008-12-04
AU2006261597A1 (en) 2006-12-28
US9241883B2 (en) 2016-01-26
NZ564129A (en) 2010-02-26
AU2006261597B2 (en) 2011-06-23
AR057402A1 (es) 2007-12-05
RU2008102637A (ru) 2009-07-27
US20140056824A1 (en) 2014-02-27
CA2612172A1 (en) 2006-12-28
BRPI0611976B1 (pt) 2018-07-10
JP5709818B2 (ja) 2015-04-30

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