CN101155825B - 抗微生物六肽 - Google Patents

抗微生物六肽 Download PDF

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Publication number
CN101155825B
CN101155825B CN200680011180.7A CN200680011180A CN101155825B CN 101155825 B CN101155825 B CN 101155825B CN 200680011180 A CN200680011180 A CN 200680011180A CN 101155825 B CN101155825 B CN 101155825B
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CN
China
Prior art keywords
seq
peptides
hexapeptides
acid
activity
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CN200680011180.7A
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English (en)
Chinese (zh)
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CN101155825A (zh
Inventor
T·J·法拉
张丽娟
S·M·哈里斯
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Helix Biomedix Inc
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Helix Biomedix Inc
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Publication of CN101155825A publication Critical patent/CN101155825A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CN200680011180.7A 2005-02-09 2006-02-07 抗微生物六肽 Active CN101155825B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65127005P 2005-02-09 2005-02-09
US60/651,270 2005-02-09
PCT/US2006/004147 WO2006086321A2 (en) 2005-02-09 2006-02-07 Antimicrobial hexapeptides

Publications (2)

Publication Number Publication Date
CN101155825A CN101155825A (zh) 2008-04-02
CN101155825B true CN101155825B (zh) 2014-11-26

Family

ID=36793611

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200680011180.7A Active CN101155825B (zh) 2005-02-09 2006-02-07 抗微生物六肽

Country Status (13)

Country Link
US (1) US7407940B2 (enExample)
EP (1) EP1853620B1 (enExample)
JP (1) JP5335241B2 (enExample)
KR (1) KR101306643B1 (enExample)
CN (1) CN101155825B (enExample)
AT (1) ATE540969T1 (enExample)
AU (1) AU2006212922B2 (enExample)
CA (1) CA2597191C (enExample)
DK (1) DK1853620T3 (enExample)
ES (1) ES2378242T3 (enExample)
PL (1) PL1853620T3 (enExample)
SI (1) SI1853620T1 (enExample)
WO (1) WO2006086321A2 (enExample)

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US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
US7713937B2 (en) * 2006-11-10 2010-05-11 Cara Therapeutics, Inc. Synthetic peptide amides and dimeric forms thereof
US8906859B2 (en) * 2006-11-10 2014-12-09 Cera Therapeutics, Inc. Uses of kappa opioid synthetic peptide amides
US7842662B2 (en) 2006-11-10 2010-11-30 Cara Therapeutics, Inc. Synthetic peptide amide dimers
ES2394377T3 (es) 2006-11-10 2013-01-31 Cara Therapeutics, Inc. Amidas de péptidos sintéticos
US8236766B2 (en) * 2006-11-10 2012-08-07 Cara Therapeutics, Inc. Uses of synthetic peptide amides
WO2008140834A2 (en) * 2007-01-16 2008-11-20 The Regents Of The University Of California Novel antimicrobial peptides
KR100879220B1 (ko) 2007-11-12 2009-01-19 아주대학교산학협력단 식물병원성 세균에 대한 항미생물 펩티드 ｋｃｍ２１
KR100879221B1 (ko) 2007-11-12 2009-01-19 아주대학교산학협력단 식물병원성 세균에 대한 항미생물 펩티드 ｋｒｓ２２
GB0724951D0 (en) * 2007-12-20 2008-01-30 Lytix Biopharma As Compounds
WO2009146885A2 (en) * 2008-06-02 2009-12-10 Spiderbiotech S.R.L. Lipidated antibacterial peptides
GB0818074D0 (en) * 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
GB0818072D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Compounds
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WO2013086003A1 (en) * 2011-12-05 2013-06-13 The Ohio State University Antimicrobial agent, bacterial strain, biosynthesis, and methods of use
CN104136626B (zh) * 2012-03-01 2017-05-03 诺沃—诺迪斯克有限公司 N‑末端修饰的寡肽及其用途
WO2014012165A1 (en) 2012-07-19 2014-01-23 Alethia Biotherapeutics Inc. Anti-siglec-15 antibodies
FR3002452B1 (fr) * 2013-02-28 2016-02-12 Dermaconcept Jmc Composition dermatologique antimicrobienne topique
TWI577697B (zh) * 2013-11-28 2017-04-11 國立清華大學 耐高鹽及抗蛋白之抗菌胜肽及其製造方法
WO2016114390A1 (ja) 2015-01-16 2016-07-21 株式会社マンダム クレンジングローション、シート化粧料、及び美容方法
US9738684B2 (en) 2015-06-29 2017-08-22 Council Of Scientific & Industrial Research N-terminally modified linear and branched polyamine conjugated peptidomimetics as antimicrobials agents
KR101855170B1 (ko) * 2015-11-18 2018-05-08 (주)노바셀테크놀로지 신규 항균 펩타이드 및 그의 용도
CN109942713A (zh) * 2018-12-28 2019-06-28 广州医科大学 新型抗菌肽及其应用
KR102170236B1 (ko) * 2019-03-19 2020-10-29 (주)노바셀테크놀로지 신규 다중 기능성 펩타이드 및 그의 용도
WO2020225255A1 (en) 2019-05-06 2020-11-12 Université De Genève Antimicrobial tailored chitosan
CN110950932B (zh) * 2020-01-09 2023-04-18 福州大学 一种修饰肽的制备及其应用
KR102220323B1 (ko) * 2020-05-15 2021-02-26 (주)노바셀테크놀로지 신규 다중 기능성 펩타이드 및 그의 용도
KR102429281B1 (ko) * 2020-05-25 2022-08-05 (주)노바셀테크놀로지 신규 안구건조증 치료용 약학적 조성물
KR102486996B1 (ko) * 2020-09-04 2023-01-10 서울대학교병원 펩타이드 및 이를 포함하는 피부 주름 개선용 조성물 및 대사성 질환 치료용 조성물
CN111925422B (zh) * 2020-09-17 2021-05-18 张雪山 抗菌肽及其在制备药物或化妆品中的应用
CN113248572B (zh) * 2021-04-30 2023-04-11 重庆理工大学 一种抗多重耐药菌环肽及其应用
CZ309857B6 (cs) * 2022-03-31 2023-12-20 Contipro A.S. Hexapeptid, kompozice zahrnující tento hexapeptid a jejich topické použití
CN116332777A (zh) * 2023-02-20 2023-06-27 华中科技大学 二芳基苯甲胺类化合物、制备及作为载体合成多肽的应用
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Also Published As

Publication number Publication date
KR20070107748A (ko) 2007-11-07
JP2008537537A (ja) 2008-09-18
ES2378242T3 (es) 2012-04-10
CA2597191A1 (en) 2006-08-17
AU2006212922A1 (en) 2006-08-17
KR101306643B1 (ko) 2013-09-12
JP5335241B2 (ja) 2013-11-06
PL1853620T3 (pl) 2012-07-31
SI1853620T1 (sl) 2012-03-30
CN101155825A (zh) 2008-04-02
EP1853620B1 (en) 2012-01-11
CA2597191C (en) 2014-04-01
ATE540969T1 (de) 2012-01-15
AU2006212922B2 (en) 2011-04-21
US7407940B2 (en) 2008-08-05
WO2006086321A2 (en) 2006-08-17
EP1853620A2 (en) 2007-11-14
US20060229252A1 (en) 2006-10-12
DK1853620T3 (da) 2012-03-26
WO2006086321A3 (en) 2007-02-22

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